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Abu Ubayd’s Understanding Of Naskh;
(Hitit University, 2022) Yaşar, M.A.; Nas, T.
In the period when Islamic sciences were formed, a large number of scholars with absolute ijtihad capacity were trained. One of the scholars mentioned is Abu ‘Ubayd al-Qāsim ibn Sallām al-Khurāsānī al-Harawī who was educated by many famous scholars of the period, had a great influence on both the scientific and political circles. For this reason, he could not be shared by different sect biographers. As a matter of fact, some Shafi’i tabaqat writers counted Ebû Ubeyd as a follower of Imam Shafii. On the other hand, some Hanbali scholars have mentioned Ebû Ubeyd among the class of Hanbali scholars. However, it was concluded that it would be more correct to see Ebû Ubeyd as an independent mujtahid rather than a follower of any madhhab. For, in his own works, the fact that he refers more to Imam Malik rather than Imam Shafii and Ahmad ibn Hanbal and sometimes refers to the views of Abu Hanifa and Imamey indicates this. Ebû Ubeyd, who came to the forefront with his faqih and muhaddis aspects, had a deep knowledge of the subject of naskh, which has a close relationship with these two sciences, and in this regard, he wrote a rare work called en-Nâsiḫ ve’l-mensûḫ fi’l-Ḳurʾâni’lʿazîz ve mâ fîhi mine’l-ferâʾiż ve’s-sünen. While revealing Ebû Ubeyd’s understanding of naskh, his work en-Nâsiḫ ve’l-mensûḫ was used as the main source. In addition to this, his other works related to the subject, especially his work called Kitâbu’l-emvâl, were among the first hand sources that were consulted. It has been tried to determine his approach to naskh based on the statements he made on the subject and the examples he gave in this regard. In this context, Ebû Ubeyd’s approach to the nature and framework of naskh and his views on the evidences that can abrogate each other are examined in this study. Ebû Ubeyd discussed the abrogation in a broader sense as “the modification of a shar’i ruling by a later evidence”, not the established meaning in the methodology as “removal of a shar’i ruling with a later shar’i proof”. In this context, naskh is also used for the allocation of public, the denial of the absolute, the statement of conciseness, the correction of a wrong understanding and the exception made from a general rule. This is known as the understanding of naskh among the companions, tābi‘īn and early convert scholars. However, although Ebû Ubeyd is at the same age as Imam Shafii and has copied and benefited from his works, it is noteworthy that he preferred the predecessor’s approach to the subject rather than the naskh understanding he adopted. It is important to investigate this. He adopted the approach of the public regarding the Shari’a evidences of Ebû Ubeyd that could naskh each other. According to him, the verses of the Qur’an can naskh each other. He gave many examples of this. Another point that draws attention here is to ascribe the concept of naskh used for the verse of the Qur’an by Ebû Ubeyd, from the Lawh-i Mahfuz, in the form of a verse whose recitation is lasting and its meaning is naskhed, and a verse that is removed from people’s hearts by canceling both its recitation and used in different meanings. Ebû Ubeyd stated that sunnah can be naskhed with sunnah, without making any distinction between ahad and mutawatir about sunnah and its naskh. However, despite giving many examples of the naskh of the âhâd sunnah with its own like, no example has been encountered of the naskh of the âhâd sunnah with its own like or with âhâd and the âhâd sunnah with the mutawatir sunnah. As it can be understood from my statements on the subject, Ebû Ubeyd saw that it is permissible to naskh both mutawatir and ahad sunnah with the Qur’an. However, while there is an example for the naskh of the ahad sunnah with the Qur’an in his related works, there is no example for the other. Although there is no clear statement on the issue that the Qur’an can be naskhed with the sunnah, it is understood from some examples that he gives permission for this. © Published by Hitit Ü niversitesi İlahiyat Fakültesi – Hitit University Divinity Faculty, Çorum, Turkey. All rights reserved.
Ahmed Anzavur: Soldier, Governor, and Rebel. a Reevaluation of a Late Ottoman Military Man
(Oriental inst Czech Acad Sci, 2023) Yelbasi, Caner
Following the Russian conquest of the North Caucasus, many Muslims from the region were exiled to the Ottoman Empire from the 1860s onwards. They were settled in different parts of the empire from the Balkans to Anatolia to the Syria and Iraq vilayets. By following this policy, the Ottoman state ensured that many Circassians would become part of the Ottoman army, ruling elites, harems and agricultural workforce. Anzavur Ahmed's family was one of them. Although he did not graduate from military school, he participated in the army during the war in Libya (1911), the Balkan Wars (1912-1913), and the First World War (1914-1918). He was also appointed as the governor of Izmit (1920). Anzavur Ahmet is portrayed as a rebel by Turkish official historiography, but in reality, he was much more than that. He was an Ottoman Governor, and supported by Ottoman administrators such as Damad Ferid and Ali Kemal, who were against the Kuvayi Milliye because they believed that the empire would eventually emerge from the chaotic atmosphere of the post-First World War period and make an agreement with the British. This article argues that although Ahmed Anzavur has been labeled a rebel and a traitor according to the official historiography, it is difficult to use these labels given the circumstances of his time.
An Examination of the Effects of Propolis and Quercetin in a Rat Model of Streptozotocin-Induced Diabetic Peripheral Neuropathy
(Mdpi, 2024) Şeker, Uğur; Celik, Hakim; Dagli, Seyda Nur; Taskin, Seyhan; Seker, Ugur; Deniz, Mustafa
The purpose of this study was to reveal the combined effects of propolis (P) and quercetin (Q) against diabetic peripheral neuropathy developing with streptozotocin-induced diabetes in rats. Sixty-four adult male rats were divided into eight equal groups: control, P (100 mg/kg/day), Q (100 mg/kg/day), P + Q (100 mg/day for both), diabetes mellitus (DM) (single-dose 60 mg/kg streptozotocin), DM + P, DM + Q, and DM + P + Q. The rats were sacrificed, and blood and sciatic nerve tissues were collected. Blood glucose and malondialdehyde (MDA) levels increased, while IL-6 and total antioxidant status decreased in the DM group (p = 0.016 and p = 0.047, respectively). Ultrastructural findings showed degeneration of the axon and myelin sheath. The apoptotic index (AI %), TNF-alpha, and IL-1 beta immunopositivity increased significantly in the DM group (p < 0.001). Morphological structures approaching those of the controls were observed in the DM + P, DM + Q, and DM + P + Q groups. Morphometric measurements increased markedly in all treatment groups (p < 0.001), while blood glucose and MDA levels, AI (%), TNF-alpha, and IL-1 beta immunopositivity decreased. In conclusion, the combined effects of propolis and quercetin in diabetic neuropathy may provide optimal morphological protection with neuroprotective effects by reducing hyperglycemia, and these may represent a key alternative supplement in regenerative medicine.
Antioxidant, Ache Inhibitory, and Anticancer Effects of Verbascum Thapsus Extract
(C M B Assoc, 2023) Keskin, Cumali; Baran, Ayse; Valioglu, Ferzane; Teng, Lei; Atalar, Mehmet Nuri; Keskin, Cumali; Beilerli, Aferin
Verbascum thapsus (Mullein) is a medicinal plant used in folk medicine to treat various ailments. For this study, the biological functions of Verbascum thapsus (VT) methanol extract were determined in vitro. The plant's methanol extract was created through the maceration process. The phytochemical composition of plant extracts was investigated using liquid chromatography-electrospray ionization tandem mass spectrometry. The antioxidant capacity of the extract was determined using the 2,2-diphenyl-1-picrylhydrazil (DPPH radical) and 2,2-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS radical). Cell lines Caco-2 (human colorectal adenocarcinoma cells), LNCaP (Lymph Node Carcinoma of Prostate), and HEK293 (Human embryonic kidney 293 cells) were used to model colon, prostate, and non-cancerous cells. The cytotoxic activity of the plant extract on the proliferation of these cells was determined by the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, a tetrazole) assay protocol. VT extract showed moderate DPPH and ABTS radical scavenging activities at 30 mg/ml concentration. With this, VT extract was determined to inhibit acetylcholinesterase (AChE) enzyme and had strong cytotoxic activity on cancerous cell lines. In addition, our findings clearly showed that the plant extract had greater cytotoxic activity on the viability of cancerous cells compared to non-cancerous (Human embryonic kidney cells; HEK293) cells. The current findings showed that V. thapsus might be a promising anti-cancer medication candidate for the treatment of human colorectal adenocarcinoma and colon cancer, as well as a good source antioxidans. Copyright: (c) 2023 by the C.M.B. Association. All rights reserved.
Arap Şiirinde Mardin’e Dair Bazı Yansımalar
(2019) Akçay, Halil
Bu çalışmamızda, ulaşılabilen kaynaklardan tespit edilebildiği kadarıyla Mardin’le ilgili yazılan şiirler ele alınmıştır. Mardin, gerek İslam fethinden önce gerek fetihten sonra Arapların yoğun göçü sonrasında Araplar için önemli bir kent haline gelmiştir. Bu husus, Mardin’in Araplarla olan coğrafi ve ticari bağlantısını güçlendirdiği gibi kültürel anlamda da aralarında bir yakınlık oluşturmuştur. Bu ve başka yönleri itibariyle Mardin, Arap şairlerinin dikkatlerini celbetmiştir. Çalışmamızda tarihi, kültürel ve sosyal yönleriyle Mardin hakkında kısaca bilgi verildikten sonra ortaya konan şiirler, Mardin’in tarihî, ilmî, sosyal ve kültürel durumuna ışık tutan hususlar açısından incelenmiş, anlam ve ön plana çıkan edebî sanatlar yönünden değerlendirilmiştir.
Assessment of preoperative anxiety and negative automatic thoughts in patients waiting for corneal transplantation
(Publishing Office of the University of Rzeszow, 2024) Tanrıverdi, Seher; Şen, Mehmet Ali; Genç, Hasan
Introduction and aim. In patients waiting for organ transplantation, increased waiting time can increase anxiety by creating negative automatic thoughts. The aim of this study is to examine the relationship between corneal transplant recipients' negative automatic thoughts and anxiety before organ transplantation. Material and methods. The population of this correlational descriptive study consisted of 108 patients waiting for cornea transplantation in the Eye Bank unit of a hospital in the south east region of Türkiye. The data were obtained from the patients presented to the ophthalmology clinic for transplantation between September and December 2022. A patient information form, the Negative Automatic Thoughts Scale, and the Trait Anxiety Scale were used to collect the data. Percentage distribution, arithmetic mean, logistic regression and correlation analysis were used in the data analysis. Results. It was determined that the mean score of the negative automatic thoughts of the transplant patients participating in the study was 100.69±47.83, and the trait anxiety mean score was 53.06±6.07. There was a positive relationship between negative automatic thoughts and trait anxiety at a moderate level, which was statistically significant (p<0.05, r=0.53). Conclusion. It was determined in the study that the patients' negative automatic thoughts and trait anxiety were high, and their anxiety increased as the negative automatic thoughts increased.
Can Serum Biomarker Values from Second-Trimester Aneuploidy Screening Predict the development of Retinopathy of Prematurity in Premature Infants?
(Kare Publishing, 2024) Savaş, Hasan Basri; Küçük, Mehmet Fatih; Savaş, Hasan Basri; Süren, Elçin; Erol, Muhammet Kazım; Yavuz, And; Sipahioğlu, Haydar
Objectives: This study aimed to evaluate serum biomarker values measured during second-trimester aneuploidy screening in terms of their predictive ability for the development of retinopathy of prematurity (ROP) in premature infants. Methods: This retrospective cohort study evaluated the data of 1985 idiopathic premature infants who underwent ROP screening from 2016 to 2022. The infants were divided into two groups according to the presence of ROP, and those with ROP were further evaluated in two subgroups based on the presence of proliferation. Comparisons were made concerning the serum multiple of the median values of unconjugated estriol (uE3), human chorionic gonadotropin (hCG), and alpha-fetoprotein (AFP) among aneuploidy screening biomarkers. Results: While 1628 premature infants were in the non-ROP group, 357 were in the ROP group. Of the infants with ROP, 72 were in the proliferative ROP group and 285 in the non-proliferative ROP group. There was no significant difference in the multiple of the median values of the evaluated serum biomarkers (uE3, hCG, and AFP) between the ROP and non-ROP groups or between the proliferative ROP, non-proliferative ROP, and non-ROP groups. Conclusion: The multiple of the median values of second-trimester aneuploidy screening serum biomarkers were not able to predict the development of ROP in premature infants. This result may have been caused by the fact that the blood tests were taken only once and in the same weeks.
Effect of Delivery Method on Breastfeeding Status in Primiparous Mothers Within the First 24 Hours
(Springer Publishing Co, 2024) Yeşil, Yeşim; Bay, Habibe; Celik, Gulbiye Dinc; Bay, Habibe; Eksioglu, Aysun; Turfan, Esin Ceber
Objective: This study aims to evaluate the effect of the delivery method on breastfeeding status of primiparous mothers during the first 24 hours. Methods: In this descriptive and analytical study, the sample consisted of 126 primiparous mothers with vaginal (n = 54) and cesarean (n = 72) deliveries. The research data were collected in a hospital through a personal information form and LATCH. Breastfeeding was assessed at the 6th, 12th, and 24th hours within the first 24 -hour period after the delivery. Results: A total of 83.3% of mothers with vaginal delivery started out breastfeeding in the first hour, while the rate was 43.1% for mothers with cesarean delivery. A total of 94.4% of mothers who had vaginal birth gave their babies colostrum, whereas the rate was 80.6% for mothers who had a cesarean birth. While there were no statistically significant differences in Applications 1 and 3 between the LATCH scores of mothers with vaginal and cesarean deliveries, Application 2 produced a significant difference (p < .05). Conclusions: Delivery method influenced the breastfeeding behavior and had an impact particularly on initiation of breastfeeding in the first hour.
The Effect of N-acetylcysteine on Amylase, Electrolytes, Vitamins and Nitrosative Stress Levels in Rats Treated with Maras Powder
(Eastern Journal of Medicine, 2020) Unsal, Velid; Belge Kurutaş, Ergül
The aim of this study is to investigate the effects of N-acetylcysteine (NAC) on amylase, electrolytes, vitamins and nitrosative stress levels in the plasma of rats treated with smokeless tobacco "maras powder". Our study consisted of three groups. Control (n = 10), the group using maras powder (n = 10), maras powder+ NAC group. To the Maras powder group, 200 mg maras powder was placed in the sublingual area under general anesthesia. It was waited for 15 minutes for Maras powder to be absorbed through mucosa. This procedure was repeated once a day and for 7 days. To the NAC group, 200 mg of Maras powder was given as in the Maras powder group and NAC was injected intraperitoneally with a dose of 100 mg / kg / day. On the 8th day, the levels of amylase, vitamins (A, C and E), electrolytes (Na+, K+, Cl- ) and, as the biomarkers of nitrosative stress, nitric oxide (NO) and nitrotyrosine (3-NTx) in the plasma of all three groups were measured by the methods of ELISA. It was determined that amylase, 3-NTx, NO, electrolyte levels increased in the group using Maras powder compared to the control and NAC groups, but vitamin levels decreased. (p <0.05). It was detected that the levels of amylase, 3-NTx, NO, electrolyte in the group treated with NAC decreased compared to the group using Maras powder, whereas vitamin levels significantly increased and approached to the values of the control group. Smokeless tobacco 'Maras powder' increases nitrosative stress and distorts the levels of vitamin A, E, C and electrolyte in the plasma. NAC has a positive function in reducing the damage caused by Maras powder.
Effects of Concomitant Use of N-acetylcysteine and Cyclosporine A on Acetaminophen-induced Acute Kidney Injury in Mice
(Agricultural Research Communication Centre, 2024) Erdem Güzel, Elif; Tektemur, Nalan Kaya; Guzel, Elif Erdem; Tektemur, Ahmet; Ozan, Ibrahim Enver
Background: Acetaminophen (APAP), a commonly used analgesic, causes acute kidney injury (AKI) in overdose although it is rare. Mitochondrial dysfunction plays a major role in the pathophysiology of renal damage, although the exact molecular mechanism is unknown. This study aimed to evaluate the potential therapeutic effect of cyclosporin A (CsA), a mitochondrial membrane permeability Methods: Male BALB/c mice were divided into Control, APAP, APAP+NAC, APAP+CsA and APAP+NAC+CsA groups (n=6). A single dose of APAP (400 mg/kg) was administered intraperitoneally. All other treatments (1200 mg/kg NAC, 50 mg/kg CsA) were performed intraperitoneally 3 h after APAP administration. All animals were decapitated and blood samples and kidney tissue samples were collected for evaluation. Serum creatinine (Cr) and blood urea nitrogen (BUN) levels were measured. The kidney tissue 8-hydroxydeoxyguanosine (8-OHdG), cytochrome c (Cytc) and 3-nitrotyrosine (3-NT) levels and cytochrome c (Cytc) expressions were determined. Result: Increased Cr and BUN levels, histopathological examinations and expressions of 8-OHdG, 3-NT and Cytc were detected in the APAP group. Combined NAC+CsA treatment sufficiently reversed oxidative stress, serum Cr and BUN levels and histopathological alterations induced by APAP. Moreover, cytc levels and renal tubular injury were remarkably reduced by combined drug treatment compared to the APAP+NAC group. These data suggest that the therapeutic effect of combined NAC+CsA treatment in mice with APAP-induced nephrotoxicity can be related to the combination of the antioxidant effect of NAC and the mitochondrial MPTP inhibitor effect of CsA.
Experimental and theoretical investigation of adsorption and inhibition properties of 2-Amino-1,3,5-triazine-4,6-dithiol against corrosion in hydrochloric acid solution on mild steel
(Elsevier, 2023) Arslanhan, Selim; Yıldız, Reşit; Döner, Ali; Yıldız, Reşit
In this work, 2-Amino-1,3,5-triazine-4,6-dithiol (2-ATD) as novel and high efficiency corrosion inhibitor has been investigated for mild steel (MS) corrosion in 0.5 M HCl solution using electrochemical methods, scanning electron microscopy (SEM), energy disperse X-ray spectroscopy (EDX), atomic force microscopy (AFM) and quantum chemical calculation methods. Potentiodynamic polarization (PDP) curves indicate that 2-ATD is mixed type inhibitor, corrosion inhibition efficiency increased with increasing inhibitor concentration and reached its value of 96.5%. Evolution of exposure time versus corrosion behavior of 2-ATD is examined in corrosive medium. While corrosion potential (Ecorr) shifted more negative values, polarization resistances (Rp) decreased after 120 h exposure time due to the corrosion process. H2 volume is measured in uninhibited and inhibited solutions (10 mM 2-ATD) after 120 h exposure time. Very low volume (3.6 mL cm-2) of H2 is obtained on MS electrode in inhibited solution after 120 h of exposure, indicating that 2-ATD covers the entire surface against aggressive attack and retards the both anodic dissolution of MS and cathodic hydrogen evolution reactions. The adsorption process proposal is the Langmuir isotherm which is most suitable. Adsorption and thermodynamic parameters show that 2-ATD has a strong adsorption effect onto MS surface and includes mixed adsorption style (physical and chemical). Corrosion current density increases with increasing temperature and high activation energy (Ea) proves the strong adsorption of 2-ATD on the MS surface. Anti-corrosion mechanism of 2-ATD is described more detail with the potential of zero charge method. SEM, EDX and AFM analysis support the obtained results of electrochemical methods and confirm the existence of protective layer and strong adsorption of 2-ATD on the MS surface. Chronoamperometry test shows that current densities are almost constant whole experiment in the presence of organic film. Finally, quantum chemical calculation method of 2-ATD in blank solution is performed to investigate the active sites for possible attachment with MS surface.
Investigation of the effects of Alfa lipoic acid on changes in maternal rat kidney caused by tobacco smoke exposure in pregnancy [Gebelikte Tütün Dumani Maruziyetinin Anne Siçan Böbrek Dokusunda Meydana Getirdigi Degişiklikler Üzerine Alfa Lipoik Asitin Etkilerinin İncelenmesi]
(Ataturk Universitesi, 2019) Erdem Güzel E.; Kaya N.; Ozan Kocamüftüoglu G.; Dabak D.Ö.; Temizer Ozan P.S.; Ozan I.E.
Çalışmada gebelikte tütün dumanına maruz kalan anne sıçanların böbrek dokusunda meydana gelen histopatolojik sonuçlar üzerine Alfa lipoik asitin etkilerinin deneysel olarak araştırılması amaçlandı. 28 adet dişi Sprague-Dawley cinsi sıçan kullanıldı. Gebe sıçanlar; Kontrol grubu, Tütün dumanı (TD) grubu, Tütün dumanı + Alfa lipoik asit (TD+ALA) grubu ve Alfa lipoik asit (ALA) grubu olmak üzere rastgele dört eşit gruba ayrıldı. TD ve TD+ALA grubundaki sıçanlar çiftleşmeden önce sekiz hafta ve gebelik süresince günde iki saat tütün dumanına maruz bırakıldı. TD+ALA ve ALA grubundaki sıçanlara ise çiftleşmeden önce sekiz hafta ve gebelik süresince gün aşırı gavaj yolu ile 20 mg/kg ALA verildi. Deney sonunda çıkarılan böbrek dokuları histolojik, immünohistokimyasal ve MDA düzeyi tayini metotları kullanılarak incelendi. TD grubuna ait böbrek kesitlerinde inflamatuar hücre artışı, Bowman boşluğunda artış, tübül lümeninde hiyalin birikimi gibi histopatolojik bulgulara rastlandı. ALA uygulaması ile histopatalojik bulguların büyük bir çoğunluğunda azalma gözlendi. TD grubunda VEGF immünreaktivitesinin kontrol grubuna göre anlamlı artış gösterdiği, TD+ALA grubunda ise TD grubuna göre anlamlı derecede azaldığı belirlendi. MDA seviyelerinde ise TD grubunda, kontrol grubuna göre anlamlı artış olduğu tespit edildi. Sonuç olarak, gebelik boyunca tütün dumanı maruziyetinin böbrek dokularında histopatolojik hasara ve damarlanmada artışa neden olduğu, ALA’nın ise bu etkilere karşı kısmen koruma sağladığı belirlendi.
Investigation of the Relationship Cellular and Physiological Degeneration in the Mandible With Aqp1 and Aqp3 Membrane Proteins
(De Gruyter Open Ltd, 2020) Çiçek, M.; Unsal, V.; Tümer, M.K.
Objective: In this study, we aimed to investigate the changes in the levels of oxidative stress and antioxidant enzymes on the mandibular bone caused by the expression of aquaporin-1 and aquaporin-3 proteins. Material and method: 14 Balb/C white mice were divided into two groups of seven, based on whether they are young or old. Mandibular tissue samples were taken for biochemical and histological analysis. Results: Findings of our study has shown that, AQP-1 and AQP-3 immunoreactivity significantly decreased in mandibular bone tissues of aged mice in comparison to younger mice (p < 0.05). MDA and AOPP levels, which are the indicators of oxidative stress, increased in elderly mice and antioxidant defense system SOD enzyme activity was decreased (p < 0.05). The TNF-α cytokine level, which is the indicator for inflammations, was found to be higher in older mice than in young mice (p < 0.05). Conclusion: As a result, it was observed that cellular damage, disruption in water – electrolyte balance and increased inflammation that occur during the natural process of aging had caused serious and irreversible disturbances. © 2020 De Gruyter. All rights reserved.
Market power in the poultry sector in Turkey
(Bogazici Universitesi, 2014) Tekgüç, Hasan; Saghaian Sayed; Tekgüç, Hasan
Rekabet Kurumu (RK), 2009 yılında 27 etlik piliç üreticisini arzı kısma ve fiyatları kontrol etme üzerinde anlaşarak kartel oluşturmaları sebebiyle cezalandırmıştır. RK, ceza kararını belli başlı etlik piliç üreticilerinin aralarında yapmış oldukları görüşme kayıtlarına ve ham fiyat verilerine istinaden vermiş olup herhangi bir istatistiksel ya da ekonometrik analizden faydalanmamıştır. Bu araştırmada, zaman serisi yöntemleri kullanılarak etlik piliç sektörü arz zincirinde piyasa gücü hem arz hem de talep açılarından test edilmiştir. Sonuçlar, etlik piliç arz zincirindeki perakende fiyat davranışlarının oligopolistik piyasa yapısı ile tutarlı olduğunu göstermektedir.
MELISSOPALNOLOGICAL ANALYSIS OF HONEY SAMPLES COLLECTED FROM ŞIRNAK CITY
(2019) Gürbüz, Semra; Gençay Çelimli, Ömür; Özenirler, Çiğdem; Mayda, Nazlı; Özkök, Aslı; Sorkun, Kadriye
Bu çalışma ile Türkiye’nin Güneydoğu Anadolu Bölgesi’nden 23 adet bal örneği toplanılmış ve bitkisel kökenleri tanımlanmak üzere araştırılmıştır. Mikroskobik analiz sonuçlarına göre, 27 bitki familyasına ait 24 taksonun polenleri teşhis edilmiştir. Melissopalinolojik analiz sonucunda; 21 bal örneği multifloral (karışık çiçek balı) ve iki tanesi ise unifloral (Myosotis balı) olarak tanımlanmıştır. Mikroskobik analizin ikinci basamağı olarak, örneklerin 10 gram baldaki toplam polen sayıları (TPS10) hesaplanmış ve bu değerlerin 1 117 ile 82 005 arasında olduğu tespit edilmiştir.
Perception of Islam in Zoroastrian Zand Literature
(Bursa IlahIyat Foundation, 2017) Alici, M.
This study analyses the perception of Islam presented in Zand literature, namely, the exegetical literature of the Zoroastrian tradition that gradually lost power as a result of Muslim conquests. Zand texts, which grew during the Sasanian era and indicate a lively theological discourse, were codified and took their final form after the Muslim conquests. Zand literature talks about Islam and Muslims in an implicit manner by means of concepts such as Tāzīg (Arab) Ag-dēnīh (evil/superstitious religion). Written for guiding Zoroastrian clergy in every subject, including theology and morals, these texts have a biased and negative attitude towards Islam and Muslims. Zands initially interpret Muslim conquests in an apocalyptic sense and emphasize that the end of world is near and consequently that evil reigns now. On the other hand, due to the obligation of living together with Muslims, Zands advise minimizing relations with Muslims in daily life. They present objections to the doctrinal attitude of Islam and aim at preserving the religious status of Zoroastrians. This paper stresses the view of the Zoroastrian tradition regarding Muslim conquests, the eventual coexistence experience and Islamic theology within the framework of Zands. © 2017 Bursa I˙lahiyat Foundation.
The predictive effect of shock index on mortality in patients with acute heart failure
(AME Publishing, 2023) Günlü, Serhat; Kayan, Fethullah; Karahan, Mehmet Zülkif
Background: The predictive usefulness of the shock index (SI), which is determined as a proportion of heart rate (HR) to systolic blood pressure (SBP), and age-adjusted SI (SI × age) for clinical outcomes other than mortality in acute heart failure (AHF) is not well established. This research aimed to examine whether SI and SI × age measured non-invasively at a patient’s bedside can identify mortality risk in patients admitted to the coronary care unit (CCU) with AHF. Methods: This research was carried out as a retrospective case-control study. Indices were calculated. The receiving operating characteristic (ROC) and Youden index were applied to calculate the optimal SI and SI × age cut-off for estimating mortality. Using multivariate analysis to determine independent indicators of mortality in patients with AHF. Results: A total of 1,468 patients who were hospitalized at the CCU with AHF were included. The population’s median age was 81 (73–91) years and 53.7% were male. In the survivor group, the median SI was 0.6 (0.5–0.75), and the median SI × age was 46 (38–58). In the non-survivor group, the median SI was 0.62 (0.55–0.81) and the median SI × age was 53 (44–66). According to the Youden index, the best value of SI was 0.56 with a specificity of 46% and a sensitivity of 70%, and the best value of SI × age was 44.8 with a specificity of 48% and a sensitivity of 76%. In the multivariate analysis, the power of SI × age to predict mortality was 2.39 times greater than other independent predictors. Conclusions: SI and SI × age calculated in the CCU may be valuable prognostic markers for identifying AHF patients at high risk for adverse outcomes.
Sağlam çocuk polikliniğine başvuran 0-1 yaş bebeği olan annelerde depresyon taraması ve depresyonda etkili risk faktörlerini belirleme
(2012) Battaloğlu İnanç, Betül; Aydemir, Nurcihan; Hatipoğlu, Sami
Sağlam çocuk polikliniğine başvuran 0-1 yaş bebeği olan annelerde Edinburgh Postnatal Depresyon Skalası (EPDS) ölçeğini kullanarak, depresyon oranlarını saptamayı ve etkili olan sosyodemografik faktörleri belirleyerek, elde edilen sonuçların diğer çalışmalarla korelasyonunu değerlendirmeyi amaçladık. Gereç ve Yöntem: 20 Temmuz- 20 Eylül 2007 tarihleri arasında, 0-1 yaş arası bebeği olan anneler çalışmaya dâhil edildi. 211 anne çalışmaya katıldı, postpartum sosyodemografik veri formu ile EPDS kullanıldı. Çalışmaya katılmayı kabul etmeyen 28 annenin, 7’sinde EPDS puanlaması depresyon için anlamlı değerlerde idi. Toplam 183 annenin verileri değerlendirmeye alındı. Annelerin sosyodemografik özelliklerini belirlemek için toplam 51 sorudan oluşan postpartum sosyodemografik veri formu kullanıldı. Depresyon yaygınlığını saptamak amacıyla annelere 10 sorudan oluşan EPDS ölçeği uygulandı. Değerlendirme 30 puan üzerinden yapıldı ve kesme puanı 13 ve üzeri ( ?13) olarak alındı. Bulgular: EPDS kesme puanı ?13 alınarak hesaplanan depresyon semptomatoloji skoru %30.6’dır. Çalışmaya katılan kadınların yaş ortalaması 27.5±5.45, yaş dağılımı 18 ile 43 arasında değişmektedir. EPDS puanı yüksek olanlarda evlilikten memnuniyet düzeyinin iyi olma oranı anlamlı düzeyde düşük; evlilikten memnuniyetleri orta ve kötü düzeyde olanlarda, psikiyatrik özgeçmişi olan annelerde ise EPDS puanları anlamlı düzeyde yüksek olarak saptanmıştır (p<0.01). Eşi çalışmayan, planlanmamış gebeliği olan, doğumda annede sağlık sorunu olan,gece doğum yapan annelerde EPDS puanlaması yüksek olarak görülmektedir (p<0.05). Bebekte sağlık sorunu olduğunu belirten, bebek bakımını güç olarak tarifleyenlerde, bebeğini emzirmeyen kadınlarda EPDS puanlaması istatistiksel olarak anlamlı düzeyde yüksek olarak saptanmıştır (p<0.01). Sonuç: Doğum sonrası depresyon birçok anneyi ve bebeği olumsuz etkileyen ciddi bir sorundur. Etkin bir tedavinin mümkün olmasına rağmen, olguların yarısından azı fark edilebilmektedir. Kitlelerin taranması, antenatal dönem, doğum sonrası erken dönem ve normal sağlam çocuk izlemleri döneminde, doğum sonrası depresyon tanısı koyabilme imkanını mümkündür. Toplumu temsil eden, büyük kitlelere yapılacak topluma dayalı çalışmalar ile geçerli, etkin bir doğum sonrası depresyon taramasının tanımlanmasına ve bu tip bir taramanın klinik olarak anne -bebek açısından hizmetin artırılmasına, olan etkisinin belirlenmesine gereksinim vardır.
A Stylistic Approach To Thomas Campion's there is a Garden in Her Face
(Rector Ciu Cyprus int Univ, 2023) Alkan, Halit
Literary works come into existence through authors' use of language units in particular ways. Style is considered as the choice of linguistic characteristics from all the probabilities in language. Stylistics attempts to create an interaction of readers with the language of a literary text to clarify how a reader understands the text. This study examines how Thomas Campion manipulated basic linguistic features to form stylistic effects in order to produce meaning in There Is a Garden in Her Face. The analysis involves lexical, semantic, grammatical (syntactic), graphological, and phonological (sound pattern) levels. It helps to clarify the context of the poem. The stylistic analysis shows that the poem is very carefully constructed. All three stanzas in the poem are grammatically parallel to each other and deal with the lady's beauty whose face is compared to a garden of heavenly paradise where every kind of delicious fruit grows there. The unity of the poem is secured by the refrain describing a beautiful lady's lips. The graphological deviation shows a system of capitalization to foreground important words such as "Roses" and "white Lilies" in the poem to represent love/passion, and innocence/purity. The phonetic parallelism reinforces the system of parallel meaning in terms of alliteration and assonance. The poem is based mostly on similes and metaphors to make the imagery of the flowers and fruit growing in a garden much more vivid. With this, the lady's physical features are portrayed. The noun cherry is used with the adjective sacred which portrays that the lady's lips have not been touched or kissed by anyone. The same line which is repeated at the end of each stanza foregrounds that this beautiful lady is unattainable unless if she says her lips are fully ripe to become most valuable. Here, female beauty signals the ideals of Elizabethan beauty: white skin, blushing cheeks, and red lips. This study shows how Campion has been able to manipulate language which is an integral part of a literary work. Campion has created changes through a systemic use of language to get his message across to readers. This study may help researchers understand how Campion used stylistic tools in his poem.
Tek Akciğer Ventilasyonun Kognitif Fonksiyonlar Üzerine Etkisi: Kesitsel Araştırma
(Türkiye Klinikleri, 2023) Çelik, Enes; Çelik, Enes; Yıldırım, Zeynep Baysal; Kuyumcu, Mahır
Amaç: Postoperatif kognitif disfonksiyon (POKD), majör cer- rahi sonrası özellikle ileri ya ş olmak üzere tüm ya ş grubu hastalarda sıkça görülür ve aylarca sebat edebilir. Etiyolojisi multifaktöriyel ol- makla birlikte, serebral oksijen sunum ve tüketim dengesini etkileyen faktörler suçlanmaktadır. Bu nedenle hipoksi gibi ciddi komplikas- yonlarla seyredebilen tek akciğer ventilasyonu (TAV) uygulanan tora- sik cerrahi hastalar ında POKD’yi mini-mental durum testi ile değerlendirerek hastalarda POKD’nin de ğerlendirilmesi amaçlandı. Gereç ve Yöntemler: Bu çalışmaya 20 yaş ve 72 yaş arası, torasik cer- rahide TAV adayı hastalar dâhil edildi. Anestezi protokolü tüm hasta- larda aynı şekilde uygulandı. Kognitif değerlendirme operasyondan 1 gün önce, operasyondan 1 ve 3 gün sonra yap ıldı. Bu amaçla Mini- Mental Durum De ğerlendirme Testi kullan ıldı. Bulgular: Çalışmaya 30 hasta dâhil edildi. TAV uygulanan hastalar ın %26,6’sında POKD tespit edildi. Hastaların yapılan mini-mental durum değerlendirme testi, ameliyat öncesi ile ameliyat sonrası 1. gün ile 3. gün arasında kognitif disfonksiyon açısından fark tespit edildi. Ameliyat sonras ı 1. gün ile ameliyat sonrası 3. gün arasında fark tespit edilmemiştir. Sonuç: Toraks cerrahisinde TAV uygulanan hastalarda erken dönem kognitif dis- fonksiyon görülmektedir. Bunda cerrahi süre, anestetik ilaçlar, hastayla ilgili parametreler etkili olmakta olup, hastalar intaroperatif yakın takip edilmeli ve ameliyat sonrasında da hastalar kognitif fonksiyonları açı- sından yakından izlenmelidir.

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