Baran, Mehmet Fırat
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Baran, M. F.
Baran, Mehmet Firat
BARAN, Mehmet Fırat
Baran, M.F.
Baran, Mehmet Firat
BARAN, Mehmet Fırat
Baran, M.F.
Job Title
Doç. Dr.
Email Address
Main Affiliation
Department of Medical Services and Techniques / Tıbbi Hizmetler ve Teknikleri Bölümü
Status
Former Staff
Website
ORCID ID
Scopus Author ID
Turkish CoHE Profile ID
Google Scholar ID
WoS Researcher ID
Sustainable Development Goals
3
GOOD HEALTH AND WELL-BEING
29
Research Products
6
CLEAN WATER AND SANITATION
3
Research Products
9
INDUSTRY, INNOVATION AND INFRASTRUCTURE
4
Research Products
16
PEACE, JUSTICE AND STRONG INSTITUTIONS
0
Research Products
1
NO POVERTY
0
Research Products
5
GENDER EQUALITY
0
Research Products
10
REDUCED INEQUALITIES
0
Research Products
15
LIFE ON LAND
1
Research Products
7
AFFORDABLE AND CLEAN ENERGY
0
Research Products
12
RESPONSIBLE CONSUMPTION AND PRODUCTION
3
Research Products
8
DECENT WORK AND ECONOMIC GROWTH
2
Research Products
14
LIFE BELOW WATER
4
Research Products
17
PARTNERSHIPS FOR THE GOALS
0
Research Products
11
SUSTAINABLE CITIES AND COMMUNITIES
3
Research Products
4
QUALITY EDUCATION
0
Research Products
2
ZERO HUNGER
3
Research Products
13
CLIMATE ACTION
0
Research Products
This researcher does not have a Scopus ID.
This researcher does not have a WoS ID.
Scholarly Output
66
Articles
61
Views / Downloads
5/0
Supervised MSc Theses
1
Supervised PhD Theses
0
WoS Citation Count
841
Scopus Citation Count
958
WoS h-index
18
Scopus h-index
19
Patents
0
Projects
2
WoS Citations per Publication
12.74
Scopus Citations per Publication
14.52
Open Access Source
44
Supervised Theses
1
| Journal | Count |
|---|---|
| Medicine Science | 5 |
| Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi | 4 |
| Applied Ecology and Environmental Research | 3 |
| Dergi | 3 |
| International Journal of Agriculture, Environment and Food Sciences | 3 |
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66 results
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Now showing 1 - 10 of 66
Other Citation - WoS: 28Citation - Scopus: 27Removal of cadmium (II) in the aqueous solutions by biosorption of Bacillus licheniformis isolated from soil in the area of Tigris River(International Journal of Environmental Analytical Chemistry, 2021) Baran, Mehmet Fırat; Duz, Mehmet ZahirBiosorption by dead bacteria is an alternative and effective method for the removal toxic elements from drinking water and waste water. The biosorption of Cd(II) from aqueous solutions was studied in a batch method by using dead bacteria Bacillus licheniformis sp. extracted from soil in the area of Tigris River. The Cd element analysis was determined using ICP-OES and AAS. The maximum adsorption capacity of biosorbent was determined, respectively, 24.51 mg/g for Cd element from Langmuir isotherm constants in the optimum conditions. The characterisation of B. licheniformis to describe behaviour of bacteria was determined such as adsorption isotherm, kinetic and thermodynamic data using FT-IR, TGA, DTA, SEM and EDX. The results suggested that the most equilibrium data of Cd(II) bioadsorption was best represented by the pseudo second-order equation and Langmuir isotherm model at different time-temperatures. The thermodynamic functions and activation energy was found to be ΔG°; −0,984 kJ/mol at 318 K, ΔH°; 15.48 kJ/mol, ΔS°; 39.08 kJ/mol and Ea; 23.24 kJ/mol and due to the ΔG°< 0, ΔH°> 0, ΔS°> 0, the reaction mechanism was determined to be physical adsorption and endothermic. This study shows that B. licheniformis sp. can be used as an effective method for the removal of Cd(II) from aqueous solutions.Article Citation - Scopus: 1The interaction methylene blue and glutathione-S-transferase purified from human erythrocytes(Journal of Planar Chromatography - Modern TLC, 2020) Acay, Hilal; Uzan, Serhat; Baran, Mehmet Fırat; Bilden, Alican; Aygün, HüsamettinIt is known that textile dyes have various risks on human health. Glutathione-S-transferase enzymes play a critical role in the detoxification of xenobiotics in living systems. This study aimed to examine the interaction of methylene blue with human erythrocyte glutathione-S-transferase purified in one step. Human erythrocyte glutathione-S-transferase was purified with approximately 750-fold purification and 30% efficiency by glutathione agarose affinity chromatography. The results showed that the enzyme was inhibited by methylene blue with an IC50 value of 1.40 mmol/L. The Ki constant of methylene blue was 1.17 mmol/L. The Lineweaver–Burk graph of the methylene blue showed that the type of inhibition was compatible with mixed type inhibition. A new third spot was also detected by thin-layer chromatography. Furthermore, the cytotoxicity of methylene blue on human erythrocytes was evaluated and it was found that the haemolysis per cent of methylene blue on erythrocytes was approximately 14%.Article GREEN SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF SILVER NANOPARTICLES (AgNPs) FROM MAIZE (ZEA MAYS L.)(APPLIED ECOLOGY AND ENVIRONMENTAL RESEARCH, 2019) Eren, abdullah; BARAN, Mehmet FıratIn recent years, the biosynthesis (green synthesis) of metal nanoparticles such as silver nanoparticles (AgNPs) have become one of the safest, most cost-effective and environmentally friendly approaches. In this study, AgNPs were synthesized using maize (Zea mays L.) leaves. For the characterization of synthesized AgNPs different techniques were used, such as X-ray diffraction spectroscopy (XRD), Ultraviolet visible (UV-Vis) spectroscopy, transmission electron microscopy (TEM), Energy dispersive X-ray spectroscopy (EDX), Fourier-transformed infrared spectroscopy (FT-IR) and Thermal gravimetric and Differential thermal analysis (TGA-DTA). The XRD results showed that AgNPs had a mean diameter of 12.63 nm and a crystal-like appearance. In addition, antimicrobial activities of synthesized AgNPs were evaluated using 3 different antibiotics against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus bacteria and Candida albicans yeast. Antifungal activity of AgNPs with antibiotics has been observed to be better than the antibiotics against Gram-positive and Gram-negative bacteria. The minimum inhibitory concentrations were found to be 0.084, 0.337 and 0.021 mg mL-1 for Escherichia coli, Staphylococcus aureus, and Candida albicans, respectively. The results revealed that AgNPs synthesized from maize leaf extract have antibacterial activity against Gram-negative Escherichia coli, Gram-positive Staphylococcus aureus and antifungal activity against Candida albicans yeast, and that the produced AgNPs could be used in the production of biomedical products and in the pharmaceutical industry.Article Citation - WoS: 26Citation - Scopus: 30Protection of Mild Steel From Corrosion in Hcl Solution Via Green Rumex Acetosella Extract: Experimental and Theoretical Studies(Elsevier, 2024) Arslanhan, Selim; Sigircik, Gokmen; Yildiz, Resit; Baran, Mehmet FiratThe efficiency and potential of green Rumex acetosella extract (RAE) RAE ) on the inhibition of the mild steel (MS) corrosion were investigated in the acidic environment. The high inhibitive capability of RAE on the mild steel was studied by electrochemical impedance spectroscopy (EIS) and linear polarization resistance (LPR) techniques. In addition, potentiodynamic (PD) polarization measurements were carried out to examine corrosion mechanism. The achieved electrochemical tests showed that RAE has a significant inhibition effect on mild steel corrosion. The results of surface analysis recorded by scanning electron microscopy (SEM), and atomic force microscopy (AFM) depicted that RAE provide strong protective layer on the steel surface via adsorptive groups. The inhibition efficiency was calculated as 99.7 %, and 99.6 % from LPR and EIS after 120 h exposure time. Adsorption free energy ( Delta G oads ) value is found as-29.79 kJ mol-1,- 1 , indicating that both physical and chemical adsorptions occur. Furthermore, the obtained experimental findings were supported with quantum chemical calculation results.Article Citation - WoS: 22Citation - Scopus: 25Determination of Antimicrobial and Toxic Metal Removal Activities of Plant-Based Synthesized (capsicum Annuum L. Leaves), Ecofriendly, Gold Nanomaterials(Wiley-v C H verlag Gmbh, 2020) Baran, Mehmet Firat; Acay, Hilal; Keskin, CumaliNanoparticles are valuable materials with widespread use. The fact that these materials are obtained by biological resources with an environmentally friendly method contributes to the development of studies in this field. Gold nanoparticles (AuNPs) from waste vegetable sources (green leaves of Capsicum annum L.) are economically and easily synthesized. The obtained particles are characterized by UV-vis spectroscopy (UV-vis), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and scanning electron microscopy (SEM) analysis. The antimicrobial activity of the particles on the pathogenic microorganisms Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 29213, Bacillus subtilis bacteria, and Candida albicans yeast are found to have a significant suppressive effect. The removal activities of eight toxic metals (Pd, Cd, Fe, Ni, Co, Mn, Zn, Pb) in Diyarbakir drinking water and artificially prepared water within different pHs are investigated. Gold nanoparticles synthesized from Capsicum annuum L. leaves are found to be effective in toxic metal removal in water samples.Article Citation - WoS: 27Citation - Scopus: 33Green Synthesis and Characterization of Silver Nanoparticles Using Anchusa Officinalis: Antimicrobial and Cytotoxic Potential(Dove Medical Press Ltd, 2025) Keskin, Cumali; Aslan, Seyhan; Baran, Mehmet Firat; Baran, Ayse; Eftekhari, Aziz; Adican, Mehmet Tevfik; Mohamed, Ali JimaleObjective: Anchusa officinalis L. (A. officinalis) is a herbaceous traditional medicinal plant used in the treatment of some diseases. The presence of its medicinal properties suggested that A. officinalis (AO) leaf extract could be used as a coating agent for the environmentally friendly production of silver nanoparticles (AgNPs). Methods: The synthesized biogenic silver nanoparticles (AO-AgNPs) were characterized using different techniques. The antimicrobial activity of AgNPs against common bacterial pathogenic strains was determined by the minimum inhibitory concentration (MIC) method. The presence of phytochemicals was determined by LSMS/MS. The MTT assay was used to investigate AO-AgNPs' cytotoxic activity in malignant (LnCap, Caco2, MDA-MB2, A549) and healthy (HEK-293) cell lines. Results: LC-MS/MS analysis detected the presence of rich phytochemicals that may be responsible for reduction reactions. Biogenic AO-AgNPs exhibited effective inhibition of the growth of pathogenic microorganisms at low concentrations. The most effective antimicrobial activity was measured as 0.5 mu g/mL MIC against S. aureus, E. coli, and C. albicans. Moreover, AO-AgNPs showed significant inhibition on the growth of cancerous cell lines, especially at a concentration of 25 mu g/mL. On the contrary, it was determined that the inhibition rate decreased in the growth of healthy cell lines due to the increase in concentration. The lowest EC50 values were determined as 15.15 mu g/mL in A549 cells. Conclusion: The obtained results showed that AO could be an important source for the synthesis of AgNPs. Especially their ability to inhibit the growth of antibiotic-resistant pathogenic bacteria at low concentrations compared to common antibiotics indicates that AOAgNPs can be used as biomedical agents in various areas. Moreover, their suppressive effect on cancerous cell lines showed that they have the potential to be used as an anticancer agent, but due to their proliferative effect on healthy cell lines, care should be taken in determining the appropriate dose.Article Citation - WoS: 8Citation - Scopus: 10Determination of Chemical Components of the Endemic Species allium Turcicum L. Plant Extract by Lc-ms/Ms and Evaluation of Medicinal Potentials(Cell Press, 2024) Ipek, Polat; Atalar, Mehmet Nuri; Baran, Ayse; Baran, Mehmet Firat; Ommati, Mohammad Mehdi; Karadag, Musa; Khalilov, RovshanThe Allium turcicum L. (Zuzubak) plant as a cultivated vegetable have various health benefits and consumed as a food. Due to the shortcoming evidence in literature and the importance of this plant in folk medicine, in the present study, for the first time, we evaluated the bioactive profile of components (using LC-MS/MS), cytotoxicity, anticancer, antioxidant, and antibacterial prospectives of Zuzubak methanol extract. Reported results show that the extract is rich in bioactive compounds and has anticancer activity with breast cancer cells (MCF-7), human prostate cancer cells (DU -145), and Human osteosarcoma cancer Cell lines of (IC50) in dose dependent manner in the concentration range of 31.25 mu g/mL and 2000 mu g/mL for 24 and 48 h. Western blotting results determined that the extract significantly suppressed the growth of U2OS, MCF-7, and DU -145 cancer cells by down expression of Ang-1 (angiogenic protein) and Beclin-1 (autophagy protein) and overexpression of Bax (a proapoptotic protein). The oxidative stress indices showed a reduction in RPE-1 and MCF-7 cells and an upsurge in U2OS and DU -145 cells. Additionally, the antimicrobial assay showed suppression of the growth of various pathogenic microorganisms in 4.00 - 8.00 mu g/concentrations of Zuzubak extract using the microdilution method. The phytochemicals identified showed promising anticancer, antioxidant effects, and antimicrobial properties, representing a valuable herbal source for drug development studies.Article Preparation and Characterization of Silver-Loaded Magnetic Activated Carbon Produced From Crataegus Monogyna for Antimicrobial and Antioxidant Applications(Wiley-v C H verlag Gmbh, 2025) Ertas, Erdal; Dogan, Serap; Baran, Ayse; Baran, Mehmet Firat; Evcil, Murat; Kurt, Baris; Aslan, Kadir SinanSecondary metabolites from several plant species have been used to cure various illnesses. Current advances allowed green synthesis nanoparticle manufacturing of metal salts from plant sources. This study involves binding activated carbon obtained from the Crataegus monogyna plant to magnetic nanoparticles and coating the resulting magnetic activated carbon nanocomposite with Ag ions (CMAC/MNPs-Ag) to produce a biomedical nanobiological material. Various techniques such as SEM, EDX, XRD, FTIR, UV-Vis, VSM, DLS, and zeta potential were used to characterize synthesized nanocomposites. CMAC/MNPs-Ag nanocomposite demonstrated activity in several processes of antioxidant activity tests. DPPH and CUPRAC activities of CMAC/MNPs-Ag nanocomposite were measured as 90.21 +/- 0.42 and 46.73 +/- 0.108 mg TE/g, respectively, while total phenolic content was measured as 27.15 +/- 0.381 mg GAE/g. Finally, the antibacterial activity of CMAC/MNPs-Ag nanocomposite was evaluated against Escherichia coli and Staphylococcus aureus by microdilution and disk diffusion techniques. The antimicrobial activity of CMAC/MNPs-Ag nanocomposite was determined using microdilution and disk diffusion techniques. For Escherichia coli, microdilution and disk diffusion were measured as 1.17 mu g mL-1 and 12 mm, respectively, while for Staphylococcus aureus, microdilution and disk diffusion were measured as 2.34 mu g mL-1 and 10 mm, respectively.Article Citation - WoS: 22Citation - Scopus: 28Thorough Examination of Polygonum Aviculare L. Plant Leaf Extract as a Green Corrosion Inhibitor for Mild Steel in 1m Hcl: Synthesis, Characterization, Observations From Surface Analysis, Experimental and Dft Studies(Elsevier, 2025) Kartal, Ahmet; Yildiz, Resit; Doner, Ali; Baran, Mehmet FiratSome industrial applications such as oil well acidification, steel pickling, acid descaling and chemical cleaning are carried out in acid environments. During these processes, corrosion of steel is inevitable. This study focuses on the extraction and corrosion behavior of Polygonum aviculare L. (PA) leaf extract as a novel corrosion inhibitor and developing a highly effective, eco-system friendly corrosion inhibitor for mild steel (MS). Corrosion behavior and mechanism of PA leaf extract are revealed on MS in 1 M HCl by Tafel curves, electrochemical impedance spectroscopy (EIS), linear polarization resistance (LPR), zero charge potential, structural and surface analysis and density functional theory (DFT). According to findings, FT-IR results reflected some groups such as -OH, -CH, C-O, C=C, C=O and ether. LC-ESI-MS/MS detected the phenolic acids, flavonoids, phytosteroids and phenolic aldehyde characterized as phytochemicals. PDP, EIS and LPR underscored that corrosion current densities decreased to 0.06 mA cm-2, polarization resistances increased to 457 ohm cm2 and inhibition efficiency increased to 96 %. In the comparison of the inhibition efficiency with the literature, PA extract exhibited outstanding corrosion inhibition efficiency (96 %). The adsorption property of PA extract matched the Langmuir process. PA extract showed an adsorption layer even at high temperatures. This behavior is confirmed by a high value of Ea (53.04 kJ/mol). Almost smooth, more compact, and homogenous surfaces were revealed by SEM. Molecules of phytochemicals in PA extract showed both physical and chemical adsorption. These interactions reduced the MS deterioration from corrosion. According to quantum chemical calculation, chlorogenic acid had the highest corrosion inhibitor efficiency among the other phytochemicals. The findings obtained from this study have the potential to contribute to the advancement of sustainable corrosion protection strategies and can provide basic guidance for industrial applications.Article The protective effects of different parts of hypericum perforatum extracts on human mononuclear leukocytes in hydrogen peroxide-induced DNA damage and their phenolic contents(Medicine Science, 2022) Aktepe, Necmettin; Keskin, Cumali; Baran, Ayşe; Atalar, Mehmet Nuri; Baran, Mehmet FıratOxidative stress is the state of the formation of some pathophysiological condition with the excessive increase of the normal amount of free radicals in the organism. In this study, the in vivo genotoxic and antigenotoxic effects of methanol and water extract and phenolic content of Hypericum perforatum flower, fruit, and seed methanol extracts were analyzed. HPLC was used to evaluate the quantities of 3,4-Dihydroxybenzoic acid, syringic acid, hydroxycinnamic acid, O-coumaric acid, caffeic acid, and catechin in the methanol extracts. The alkaline comet test was used to assess the DNA damage and protective effects of H. perforatum flower fruit, seed methanol, and water extract on human mononuclear leukocytes. The amounts of catechin and caffeic acid in seed methanol extract were found as quite high when compared to other extracts. The highest protective effects were seen at 10 and 50μg/ml concentrations of seed methanol extract. The optimum doses of fruit, flower, and seed extracts obtained from H. perforatum neutralized the genotoxic effect. This effect is stronger in seed methanol extract than other extracts. We suggest that more research is needed to evaluate the effects of H. perforatum phytochemicals in vitro and in vivo.
