Aktan, Adem

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https://hdl.handle.net/20.500.12514/7397
Name Variants
Aktan, A.
Aktan, Adem
Job Title
Doç. Dr.
Email Address
ademaktan@artuklu.edu.tr
Main Affiliation
Department of Internal Medical Sciences / Dahili Tıp Bilimleri Bölümü
Status
Current Staff
Website
ORCID ID
0000-0003-0505-9784
Scopus Author ID
56783879500
Turkish CoHE Profile ID
189492
Google Scholar ID
m76i1JgAAAAJ
WoS Researcher ID
GMX-2603-2022
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cv_A-1873_ingilizce.pdf (421.69 KB)
cv_A-1873_turkce.pdf (425.76 KB)

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GENDER EQUALITY5
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CLEAN WATER AND SANITATION6
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DECENT WORK AND ECONOMIC GROWTH8
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INDUSTRY, INNOVATION AND INFRASTRUCTURE9
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PEACE, JUSTICE AND STRONG INSTITUTIONS16
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74

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78

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JournalCount
International Journal of Cardiovascular Sciences3
Dicle Tıp Dergisi3
Vascular2
Aging Clinical and Experimental Research2
Annals of Vascular Surgery2
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    KRONİK HASTALIĞI OLAN BİREY VE AİLE İLE İLETİŞİM
    (2023) Aktan, Adem; Karahan, Mehmet Zülkif
    Kronik hastalık, uzun süreli tedavi gerektiren ve hayatı boyunca sürebilecek bir sağlık durumunu ifade eder. Bunlar, diyabet, hipertansiyon, kalp hastalığı, kanser, multipl skleroz gibi bir dizi farklı hastalığı içerebilir. Kronik hastalık tanısı alan bireylerin ve ailelerin yaşamlarında büyük bir etkiye sahip olabilir ve duygusal, sosyal ve fiziksel zorluklara neden olabilir. Bu nedenle, kronik hastalık tanısı almış bireylerle ve aileleriyle iletişim kurarken dikkatli ve duyarlı olmak önemlidir (1). İletişim, bireylerin duygularını ifade etmelerine, endişelerini paylaşmalarına ve birbirleriyle destek sağlamalarına yardımcı olabilir. Kronik hastalıkla ilgili iletişim becerileri, bireylerin sağlıklı bir şekilde başa çıkmalarına ve daha iyi sonuçlar elde etmelerine yardımcı olabilir. Kronik hastalık tanısı almış bireyler ve aileleri arasındaki iletişim, aşağıdaki bazı temel prensiplere dikkat ederek etkili bir şekilde gerçekleştirilebilir: Açık iletişim kurma: Kronik hastalık tanısı almış bir bireyin ve ailesinin duygularını ve deneyimlerini anlamak için empati kurmak önemlidir. Açık iletişim, dürüst, saygılı ve etkili bir iletişim tarzını içerir. Kronik hastalık tanısı almış bir birey ve ailesiyle iletişim kurarken açık ve net olmak önemlidir. VII. Sonuç Kronik hastalık tanısı almış bireyler ve aileleriyle etkili iletişim kurmak önemlidir. Etkili iletişim, hastaların sağlık sonuçlarını, yaşam kalitesini ve memnuniyetini artırabilir. Ailelerin de katılımıyla birlikte, uygun tıbbi bakım sağlanabilir ve sağlıklı bir iyileşme süreci desteklenebilir. Bu nedenle, sağlık profesyonellerive diğer ilgili paydaşlar, hastalarla etkili iletişim kurma becerilerini geliştirmek için yönlendirilmelidir. Kronik hastalık yönetiminde etkili iletişim, hastaların ve ailelerinin gereksinimlerini anlamak ve onları desteklemek için vazgeçilmez bir araçtır.
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    Citation - WoS: 1
    Citation - Scopus: 1
    Ability of Cha2ds2-vasc/R2cha2ds2-vasc Scores To Predict Complications Related To Cardiac Implantable Electronic Devices
    (Wiley, 2025) Aktan, Adem; Kilic, Raif; Guzel, Hamdullah; Tastan, Ercan; Oksul, Metin; Guzel, Tuncay; Soner, Serdar
    BackgroundGlobally, the number of cardiac implantable electronic devices (CIEDs) is increasing. In our study, we aimed to investigate whether CHA(2)DS(2)-VASc and R(2)CHA(2)DS(2)-VASc scores are predictive of CIED-related complications. MethodsOur investigation was carried out with a multicenter retrospective design. Patients who underwent CIED surgery at two cardiac centers in Turkey between January 2011 and May 2023, 1676, were evaluated. The patients were divided into two groups according to their R(2)CHA(2)DS(2)-VASc scores. Patients with R(2)CHA(2)DS(2)-VASc >= 5 were included in group 1 (380 patients), and patients with R(2)CHA(2)DS(2)-VASc < 5 (1296 patients) were included in group 2. The primary outcome was defined as the cumulative events. Each component of cumulative events, such as hematoma, pericardial effusion, pneumothorax, and infection, was also defined as a secondary outcome. ResultsThe study's patient population had an average age of 62.9 +/- 14 years. Pneumothorax (1.8% vs. 1.3%, p = 0.444), pericardial effusion or tamponade (0.35% vs. 0.2%, p = 0.659), and clinically significant hematoma (1.1% vs. 0.6%, p = 0.376) were comparable between the groups. Infection-related devices and cumulative events classified as primary outcomes were higher in the R(2)CHA(2)DS(2)-VASc >= 5 group (6.1% vs. 1.2%, p < 0.001; 7.6% vs. 3.2%, p < 0.001, respectively). Modeling analyses showed that the CHA(2)DS(2)-VASc score and HT were also independent predictors of device-related infection and cumulative events. ConclusionIn the R(2)CHA(2)DS(2)-VASc >= 5 groups, infection related to the device system and cumulative events were higher. Patients with an R(2)CHA(2)DS(2)-VASc score of 5 or more and a high CHA(2)DS(2)-VASc score should be evaluated more carefully regarding infection and cumulative events before and after the operation.
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    Citation - WoS: 11
    Citation - Scopus: 12
    The Effectiveness of HALP Score in Predicting Mortality in Non-ST Myocardial Infarction Patients
    (Lippincott Williams and Wilkins, 2025) Kiliç, R.; Guzel, T.; Aktan, A.; Güzel, H.; Kaya, A.F.; Çankaya, Y.
    Background: The HALP score, measured based on hemoglobin, albumin, lymphocyte, and platelet levels, is regarded as a novel scoring system that indicates the status of systemic inflammation and nutritional health. Our study aimed to evaluate the relationship between HALP score and prognosis in non-ST-elevation myocardial infarction (NSTEMI) patients. Methods Between 1 January 2020 and 1 January 2022, 568 consecutive patients diagnosed with NSTEMI from a single center were included in the study retrospectively. The patients were divided into two equal groups according to the median HALP cutoff value of 44.05. Patients were followed for at least 1 year from the date of admission. Results The average age of the patients was 62.3±10.6 years and 43.7% were female. In-hospital and 1-year mortality were found to be significantly higher in the group with low HALP scores (6.0 vs. 2.1%, P=0.019 and 22.5 vs. 9.9%, P<0.001, respectively). In receiver operating characteristic curve analysis, a cutoff level of 34.6 of the HALP score predicted 1-year mortality with 71% sensitivity and 65% specificity (area under the curve: 0.707, 95% confidence interval: 0.651-0.762, P<0.001). In Kaplan-Meier analysis, higher mortality rates were observed over time in the group with lower HALP scores (log-rank test=16.767, P<0.001). In Cox regression analysis, the HALP score was found to be an independent predictor of 1-year mortality (odds ratio: 0.969, 95% confidence interval: 0.958-0.981, P<0.001). Conclusion We found that a low HALP score could predict in-hospital and 1-year mortality in patients admitted to the hospital with a diagnosis of NSTEMI. © © 2024 Wolters Kluwer Health, Inc. All rights reserved.
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    Impact of Iron Deficiency Anemia on Electrocardiographic Markers in Pediatric Patients
    (Wiley, 2025) Orhan, Ozhan; Aktan, Adem
    Background Iron deficiency anemia (IDA) is a condition in which healthy red blood cells are inadequately produced in children and, if left untreated, can lead to serious health problems. The impact of IDA on electrocardiographic (ECG) markers in children has not been sufficiently investigated, emphasizing the need for more comprehensive studies in this regard.Methods This study, conducted in our clinic, includes 75 children diagnosed with anemia and a control group of 77 healthy children. ECG analysis was employed to assess depolarization and repolarization parameters, including measurements such as QT interval, Tp-e interval (Tp-e), cardiac electrophysiological balance index (iCEB), and frontal QRS-T angle.Results The ECG parameters of children with IDA and ferritin levels below 15 ng/mL were contrasted with those of healthy children having ferritin levels exceeding 25 ng/mL. The anemic group exhibited significantly higher values for QT interval, corrected QT (QTc), Tp-e, P-wave dispersion (PWd), QT dispersion (QTd), corrected QTd, Tp-e dispersion, iCEB, and corrected iCEB compared to the control group. In the Pearson correlation analysis, a weak and negative correlation was found between ferritin levels and QT dispersion (p = 0.002) and QTc dispersion (p = 0.039). No significant relationship was detected between other parameters. These observations imply that IDA in children might induce alterations in depolarization and repolarization, potentially elevating the susceptibility to arrhythmias.Conclusions Our study demonstrated significant alterations in certain electrocardiographic parameters in children with IDA. These findings suggest that iron deficiency may influence cardiac repolarization and highlight the potential role of ECG monitoring in the early stages.
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    Citation - WoS: 2
    Citation - Scopus: 2
    The Effect of Aortic Angulation on Clinical Outcomes of Patients Undergoing Transcatheter Aortic Valve Replacement
    (Soc Brasil Cirurgia Cardiovasc, 2024) Aktan, Adem; Demir, Muhammed; Aslan, Burhan; Guzel, Tuncay; Karahan, Mehmet Zulkuf; Kilic, Raif; Ertas, Faruk
    Introduction: The aim of this study was to assess the impact of aortic angulation (AA) on periprocedural and in -hospital complications as well as mortality of patients undergoing Evolut (TM) R valve implantation. Methods: A retrospective study was conducted on 264 patients who underwent transfemoral-approach transcatheter aortic valve replacement with self-expandable valve at our hospital between August 2015 and August 2022. These patients underwent multislice computer tomography scans to evaluate AA. Transcatheter aortic valve replacement endpoints, device success, and clinical events were assessed according to the definitions provided by the Valve Academic Research Consortium -3. Cumulative events included paravalvular leak, permanent pacemaker implantation, new-onset stroke, and in -hospital mortality. Patients were divided into two groups, AA <= 48(degrees) and AA > 48(degrees), based on the mean AA measurement (48.3 +/- 8.8) on multislice computer tomography. Results: Multivariable logistic regression analysis was performed to identify predictors of cumulative events, utilizing variables with a P-value < 0.2 obtained from univariable logistic regression analysis, including AA, age, hypertension, chronic renal failure, and heart failure. AA (odds ratio [OR]: 1.73, 95% confidence interval [CI]: 0.89-3.38, P=0.104), age (OR: 1.04, 95% CI: 0.99-1.10, P=0.099), hypertension (OR: 1.66, 95% CI: 0.82-3.33, P=0.155), chronic renal failure (OR: 1.82, 95% CI: 0.92-3.61, P=0.084), and heart failure (OR: 0.57, 95% CI: 0.27-1.21, P=0.145) were not found to be significantly associated with cumulative events in the multivariable logistic regression analysis. Conclusion: This study demonstrated that increased AA does not have a significant impact on intraprocedural and periprocedural complications of patients with new generation self-expandable valves implanted.
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    Citation - WoS: 1
    Citation - Scopus: 2
    Association Between the Triglyceride-Glucose Index and Contrast-Induced Nephropathy in Chronic Total Occlusion Patients Undergoing Percutaneous Coronary Intervention
    (Bmc, 2025) Soner, Serdar; Aktan, Adem; Kilic, Raif; Guzel, Hamdullah; Tastan, Ercan; Oksul, Metin; Guzel, Tuncay
    Objective The triglyceride glucose (TyG) index is a biomarker of insulin resistance and is associated with an increased risk of cardiovascular events. Contrast-induced nephropathy (CIN) is an important complication that causes poor outcomes in patients undergoing percutaneous coronary intervention (PCI). In this study, we aimed to investigate the relationship between the TyG index and CIN and mortality in patients who underwent PCI due to chronic total coronary occlusion (CTO). Methods Two hundred eighteen individuals from three separate medical centers who underwent procedural PCI between February 2010 and April 2012 and had a CTO lesion in at least one coronary artery were recruited. According to the TyG index, patients were divided into two groups. Patients with a TyG index >= 8.65 were included in Group 1, and patients with a TyG index < 8.65 were included in Group 2. Patients were followed up for 96 months. The main outcome was the development of CIN and mortality. Results The mean age of the patients (65.8 +/- 10.94 vs. 61.68 +/- 11.4, P = 0.009), diabetes mellitus (60 [44.8%] vs. 11 [13.1%], P < 0.001), and dyslipidemia rates (52 [38.8%] vs. 21 [25%], P = 0.036) were higher in group 1. In multivariable logistic regression analysis, it was seen that age (OR = 1.04, 95% CI = 1.01-1.08, P = 0.020), chronic kidney disease (OR = 2.34, 95% CI = 1.02-5.33, P = 0.044), peripheral artery disease (OR = 5.66, 95% CI = 1.24-25.91, p = 0.026), LVEF (OR = 0.95, 95% CI = 0.92-0.99, P = 0.005), LDL cholesterol levels (OR = 1.00, 95%CI = 1.00-1.02, P = 0.024) and TyG index (OR = 2.17, 95% CI = 1.21-3.89, P = 0.009) were independent predictors of the development of CIN. Conclusion Our study demonstrates a correlation between the TyG index and the prevalence of CIN in patients with CTO undergoing PCI. Adding the TyG index to the routine clinical evaluation of patients with CTO undergoing PCI may help protect patients from the development of CIN.
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    Citation - WoS: 1
    Citation - Scopus: 1
    A Novel Determinant of Prognosis in Acute Pulmonary Edema: Intermountain Risk Score
    (Kare Publ, 2024) Kilic, Raif; Aktan, Adem; Guzel, Tuncay; Kaya, Ahmet Ferhat; Guzel, Hamdullah; Arslan, Bayram; Cankaya, Yusuf; Işık, Mehmet Ali
    Objective: The Intermountain Risk Score (IMRS), calculated using age, gender, complete blood count (CBC), and simple laboratory analyses, is an easy-to-use and cost-effective tool developed to predict mortality. In our study, we aimed to determine whether the IMRS could predict mortality in patients admitted to the hospital with a diagnosis of acute pulmonary edema. Methods: A total of 371 patients who were admitted with a diagnosis of pulmonary edema, were included in our study. The IMRS of the patients was determined using a calculation tool, and the patients were divided into three groups based on the determined value: low, moderate, and high IMRS. Results: The patients included in our study comprised 208 women and 163 men, with an average age of 68.7 years. There was a statistically significant difference between the patient groups concerning both 1-month and 1-year mortality rates. Additionally, there was a significant difference in IMRS between patients who developed in-hospital, 1-month, and 1-year mortality and those who survived. In the Receiver Operating Characteristic (ROC) analysis, a cutoff value of 15.5 for the IMRS predicted both 1-year and 1-month mortality. In the Kaplan-Meier analysis, the highest mortality risk was observed in the high IMRS group and the lowest mortality risk in the low IMRS group. Conclusion: Our research results show that the IMRS strongly predicts both short-term and long-term mortality in patients hospitalized with a diagnosis of acute pulmonary edema.
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    Citation - WoS: 7
    Citation - Scopus: 7
    The Performance of the Naples Prognostic Score in Predicting One-Year Mortality and Major Adverse Cardiovascular Events After Transcatheter Aortic Valve Implantation in Patients With Severe Aortic Stenosis
    (Polish Cardiac Soc, 2025) Gitmez, Mesut; Guzel, Tuncay; Kis, Mehmet; Coskun, Ferhat; Isik, Mehmet Ali; Aktan, Adem; Ertas, Faruk
    Background: Existing risk scores for transcatheter aortic valve implantation (TAVI) may not fully capture patient complexity. Combining nutritional and inflammatory markers, the NPS (the NAPLES prognostic score) might improve outcome prediction. Aims: This study investigated the associations of the NPS with one-year mortality and major adverse cardiovascular events (MACEs) in TAVI patients. Material and methods:This retrospective analysis included 222 patients with severe aortic stenosis who underwent TAVI. The NPS was calculated based on the serum alb & uuml;min concentration, cholesterol concentration, lymphocyte/monocyte ratio, and neutrophil/lymphocyte ratio. The patients were subsequently categorized into two groups: the low-NPS group (NPS 0-2) and the high-NPS group (NPS 3-4). Results: A high NPS was significantly associated with increased one-year mortality (4.8% vs. 23.7%; P <0.001) and MACE rates (7.2% vs. 35.9%; P <0.001). Cox regression analysis demonstrated that a high NPS was an independent predictor of both mortality (HR, 5.94; 95% CI, 2.03-17.37; P = 0.001) and MACEs (HR, 5.09; 95% CI, 2.15-12.02; P <0.001). Conclusions: The NPS emerged as a potential predictor of long-term mortality and MACEs in TAVI patients. Further validation through larger, multicenter, studies is warranted.This research contributes valuable data on the role of the NPS in TAVI risk stratification.
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    Citation - WoS: 12
    Citation - Scopus: 12
    Comparison of Pain Levels of Traditional Radial, Distal Radial, and Transfemoral Coronary Catheterization
    (Assoc Medica Brasileira, 2023) Aslan, Muzaffer; Gunlu, Serhat; Karahan, Mehmet Zulkuf; Kilic, Raif; Guzel, Tuncay; Aktan, Adem; Arslan, Bayram
    OBJECTIVE: The aim of our study was to compare the traditional radial artery, distal radial artery, and transfemoral artery, which are vascular access sites for coronary angiography, in terms of pain level using the visual analog scale.METHODS: Between April 2021 and May 2022, consecutive patients from three centers were included in our study. A total of 540 patients, 180 from each of the traditional radial artery, distal radial artery , and transfemoral artery groups, were included. The visual analog scale was applied to the patients as soon as they were taken to bed. RESULTS: When the visual analog scale was compared between the groups, it was found to be significantly different (transfemoral artery: 2.7 & PLUSMN;1.6, traditional radial artery: 3.9 & PLUSMN;1.9, and distal radial artery: 4.9 & PLUSMN;2.1, respectively, p<0.001). When the patients were classified as mild, moderate, and severe based on the visual analog scale score, a significant difference was found between the groups in terms of body mass index, process time, access time, and number of punctures (p<0.001). Based on the receiver operating characteristic analysis, body mass index>29.8 kg/m2 predicted severe pain with 72.5% sensitivity and 73.2% specificity [(area under the curve: 0.770, 95%CI: 0.724-0.815, p<0.0001)].CONCLUSION: In our study, we found that the femoral approach caused less access site pain and a high body mass index predicts severe pain.