Sedigh Maroufi, ShahnamMoradimajd, ParisaMoosavi, Seyed Ali AkbarImani, FarnadSamaee, HamidrezaOguz, Mehmet2021-06-292021-06-292019https://pubmed.ncbi.nlm.nih.gov/31903330/https://doi.org/10.5812/aapm.92072https://hdl.handle.net/20.500.12514/2631Background: Postoperative nausea and vomiting (PONV) is considered a common complication of anesthesia, which, particularly in eye surgery, may exert pressure on stitches and open or leak the surgical wound, leading to bleeding. Objectives: We aimed to study the effect of ginger on PONV and changes in vital signs after eye surgery. Methods: In this triple-blind randomized controlled trial, 120 candidate patients for eye surgery were divided into group A (n = 40) and group B (n = 40). Patients in group A received the capsules of ginger 1 g while patients in group B received a placebo one hour before the procedure with 30 mL water. The incidence of nausea and the frequency of vomiting were evaluated at 0, 15, 30 minutes, and 2 hours after the operation. Also, the vital signs of the participants were recorded at certain times. Results: The results demonstrated a statistically significant difference in the frequency of nausea between group A and group B (P < 0.05). The severity of nausea was lower in group A than in group B immediately and 2 hours after recovery (P < 0.05). The incidence of vomiting was significantly lower in group A than in group B (P < 0.05). The vital signs were not significantly different between group A and group B (P > 0.05). Conclusions: Ginger was effective in the prevention of PONV after eye surgery but had no impact on vital signs. Hence, ginger is proposed to use as a low-cost, prophylactic measure for PONV reduction.en10.5812/aapm.92072info:eu-repo/semantics/openAccessGinger, Nausea, Vomiting, Eye Surgery, PONVArticle95152-s2.0-85075513817