Baran, AyseBaran, Mehmet FiratYildiz, ResitEftekhari, AzizOzkan, Ahmet IsmailKesharwani, Prashant2026-02-022026-02-0220260026-265X1095-9149https://doi.org/10.1016/j.microc.2026.117015Selenium nanoparticles are highly valuable materials. A multitude of methods is available for obtaining these items. Green synthesis methods are attracting significant attention, and due to the therapeutic characteristics of selenium, these advantageous compounds will become more prominent. This study entailed the rapid, uncomplicated, and cost-effective production of selenium nanoparticles (Se NPs) employing the herb "evelik" from Eastern Anatolia. The properties of the synthesized Se NPs were examined using Ultraviolet-Visible Spectroscopy (UV-Vis), Fourier-transform Infrared Spectroscopy (FTIR), Transmission Electron Microscopy (TEM), Scanning Transmission Electron Microscopy (STEM), X-ray Diffraction (XRD), and Energy-Dispersive X-ray Spectroscopy (EDX). Se nanoparticles, mostly spherical in shape, demonstrated a peak absorbance wavelength of 230 nm and a crystalline dimension of 62.7 nm. Their antibacterial effectiveness against pathogenic strains was evaluated using microdilution methods. The application demonstrated efficacy against Candida albicans ATCC 10231, Staphylococcus aureus ATCC 25923, and Escherichia coli ATCC 11229 within a dose range of 2.00-8.00 mu g mL- 1. Se NPs were analyzed on Prostate Carcinoma cells and Retinal Pigment Epithelial cells via the Methylthiazol Tetrazolium assay. The anticancer impact was shown to be substantial at a concentration of 62.5 mu g mL- 1, exhibiting a rate of 79.78%.en10.1016/j.microc.2026.117015info:eu-repo/semantics/closedAccessAntimicrobialAnticancerEnvironmentally FriendlyRumex Acetosella L.Selenium Nanoparticles (Se NPs)Article2-s2.0-105028414201