Atalar, Mehmet NuriBaran, AyşeBaran, Mehmet FıratKeskin, CumaliAktepe, NecmettinYavuz, Ömerİrtegun Kandemir, Sevgi21.02. Department of Medical Services and Techniques / Tıbbi Hizmetler ve Teknikleri Bölümü09.01. Department of Nursing / Hemşirelik Bölümü9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi21. Vocational School of Health Services / Sağlık Hizmetleri Meslek Yüksekokulu01. Mardin Artuklu University / Mardin Artuklu Üniversitesi2021-10-252021-10-252021Atalar, M. N., Baran, A., Baran, M. F., Keskin, C., Aktepe, N., Yavuz, Ö., & İrtegun Kandemir, S. (2021). Economic fast synthesis of olive leaf extract and silver nanoparticles and biomedical applications. In Particulate Science and Technology (pp. 1–9). Informa UK Limited. https://doi.org/10.1080/02726351.2021.1977443https://www.webofscience.com/wos/woscc/full-record/WOS:000698911200001?AlertId=d383397b-4355-449e-9419-70f9e0e77c15&SID=F1vcqQId99jRM5IHv6Zhttps://www.scopus.com/record/display.uri?eid=2-s2.0-85115608143&origin=resultslist&sort=plf-f&src=s&sid=2fea2c7dd67ef0f6c5ca731c097e9f7a&sot=b&sdt=b&sl=34&s=DOI%2810.1080%2f02726351.2021.1977443%29&relpos=0&citeCnt=0&searchTerm=https://doi.org/10.1080/02726351.2021.1977443https://hdl.handle.net/20.500.12514/2900In this study, silver nanoparticles (AgNPs) were synthesized economically and simply using an environmentally friendly method with the extract obtained from agricultural waste olive leaves. AgNPs synthesized according to the analysis data were determined to have maximum absorbance at 433.5 nm wavelength, spherical appearance, 7.2 nm crystal nano size and -19.9 mV zeta potential. It was determined by the microdilution method with Minimum Inhibition Concentration (MIC) that AgNPs exert a suppressive effect on the growth of pathogen gram-negative, positive bacteria and yeast at very low concentrations. The cytotoxic effects of the particles were investigated on healthy cell lines (HDF) and cancerous cell lines (U118, CaCo-2, Skov-3). AgNPs showed up to 70% suppression in cancer cell lines.en10.1080/02726351.2021.1977443info:eu-repo/semantics/closedAccessCytotoxic, effect, biocompatible, extract, MIC, zeta potentialArticle2-s2.0-85115608143