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Sağlık ve Bakım Hizmetleri Bölümü Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12514/160

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Browsing Sağlık ve Bakım Hizmetleri Bölümü Koleksiyonu by Author "Jahan, Israt"

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    Book Part
    Advances and applications of nanomaterial-assisted phytoremediation
    (CRC Press, 2023) Jahan, Israt
    Nanotechnology has the potential to drastically transform the agri-food sector with its significant applications to improve agricultural productivity and the efficiency of agrochemicals. The food sector has benefitted from the inclusion of nanoparticles in food matrixes and the nanoencapsulation of nutraceuticals. Smart packaging mate rials designed with the help of nanotechnology have been used for increasing the shelf life of stored food products. Nanomaterials have been extensively used for the delivery of important agrochemicals to enhance their bioefficacy, prevent their deg radation, and control their release. Various nanomaterials have been explored for remediation of arising environmental issues. Nanotechnology has also made a useful contribution to the utilization of huge agricultural and food wastes for production of valuable products. The existing and emerging applications of nanotechnology will contribute to environmental sustainability
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    Article
    The Effects of Silver Nanoparticles (AgNPs) on Thermophilic Bacteria: Antibacterial, Morphological, Physiological and Biochemical Investigations
    (MDPI, 2024) Jahan, Israt; Matpan Bekler, Fatma; Tunç, Ahmed; Güven, Kemal
    Since thermophilic microorganisms are valuable sources of thermostable enzymes, it is essential to recognize the potential toxicity of silver nanoparticles used in diverse industrial sectors. Thermophilic bacteria Geobacillus vulcani 2Cx, Bacillus licheniformis 3CA, Paenibacillus macerans 3CA1, Anoxybacillus ayderensis FMB1, and Bacillus paralicheniformis FMB2-1 were selected, and their MIC and MBC values were assessed by treatment with AgNPs in a range of 62.5-1500 μg mL-1. The growth inhibition curves showed that the G. vulcani 2Cx, and B. paralicheniformis FMB2-1 strains were more sensitive to AgNPs, demonstrating a reduction in population by 71.1% and 31.7% at 62.5 μg mL-1 and by 82.9% and 72.8% at 250 μg mL-1, respectively. TEM and FT-IR analysis revealed that AgNPs caused structural damage, cytoplasmic leakage, and disruption of cellular integrity. Furthermore, cell viability showed a significant decrease alongside an increase in superoxide radical (SOR; O2-) production. β-galactosidase biosynthesis decreased to 28.8% level at 500 μg mL-1 AgNPs for G. vulcani 2Cx, 32.2% at 250 μg mL-1 for A. ayderensis FMB1, and 38.8% only at 62.5 μg mL-1, but it was completely inhibited at 500 μg mL-1 for B. licheniformis 3CA. Moreover, B. paralicheniformis FMB2-1 showed a significant decrease to 11.2% at 125 μg mL-1. This study is the first to reveal the toxic effects of AgNPs on thermophilic bacteria.