Browsing by Author "Dundar, A."

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Determination of Cytotoxic, Anticholinesterase, Antioxidant and Antimicrobial Activities of Some Wild Mushroom Species
(Informa Healthcare, 2016) Dundar, A.; Okumus, V.; Ozdemir, S.; Celik, K.S.; Boğa, M.; Ozcagli, E.
In the performed study of methanol extraction of wild edible mushroom species; Agaricus arvensis, Agaricus campestris, Armillaria mellea, Fomes fomentarius, Coprinus micaceus, Coriolus versicolor and Lactarius deliciosus were examined for screening their cytotoxic, anticholinesterase, antioxidant and antimicrobial capacity. Phenolic acid composition of mushrooms was also analysed. L. deliciosus and F. fomentarius were generally showed the highest activities at antioxidant test systems (metal chelating, superoxide anion radical scavenging, total antioxidant, 2,2-diphenyl-1-picrylhydrazyl radical scavenging and reducing power activity tests). The highest activities at antimicrobial activity displayed by A. arvensis and as 18 ± 0.8 against to Staphylococcus aureus. The best IC50 values of mushroom methanol extracts at anticancer activities on HeLa and NRK-52E were 7.09 and 18.23 mg/mL exhibited by C. micaceus and A. campestris, respectively. The highest butyrylcholinesterase activity exhibited by L. deliciosus. Total amount of phenolic acids were found as 1,224.70 mg/kg at L. deliciosus. © 2016 The Author(s). This open access article is distributed under a Creative Commons Attribution (CC-BY) 4.0 license.
Different peripheral substituted phthalocyanines: Synthesis, characterization, aggregation behavior, antioxidant and antibacterial activity
(PLEIADES PUBLISHING INC, 2015) Celebi, M.; Agirtas, M. S.; Dundar, A.
In this study, a novel phthalonitrile, 4-chloro-5-(2-((2-hydroxyethyl)(p-tolyl)amino)ethoxy)phthalonitrile (3), and its metallophthalocyanine derivatives (4-6) are prepared by cyclotetramerization with appropriate metal salts in dimethylformamide. The newly prepared compounds have been characterized by several spectroscopic techniques. All compounds are evaluated for their antioxidant and antibacterial potential. For the antioxidant studies, three tests are applied; DPPH (2,2-diphenyl-1-picrylhydrazylradical) scavenging, metal chelating and reducing power activity. Compound 4 exhibits the best DPPH scavenging activity as 35.2% at 100 mg/L concentration. The metal chelating activities of compounds 3 and 4 are 69.7% and 56.4%, respectively. Reducing power activities of compounds 3 and 4 are higher than alpha-tocopherol which is used as positive control. All compounds show moderate antibacterial activity when compared to the standard antibiotics, amikacin and tetracycline.
Preparation, spectral studies, theoretical, electrochemical and antibacterial investigation of a new Schiff base and its some metal complexes
(ELSEVIER SCIENCE BV, 2014) Ilhan, S.; Baykara, H.; Seyitoglu, M. S.; Levent, A.; Ozdemir, S.; Dundar, A.; Oztomsuk, A.; Cornejo, M. H.
A new Schiff base ligand, 1,6-Bis(2-(5-bromo-2-hydroxybenzylideneamino)-4-chlorophenoxy)hexane was synthesized. Some Schiff metal complexes of the new Schiff base were prepared by the reaction of some metal salts and the Schiff base. The complexes are non-electrolytes as shown by their molar conductivities (Lambda M). The structures of metal complexes are proposed from elemental analysis, FT-IR, UV-vis, magnetic susceptibility measurements, molar conductivity measurements, mass spectra and thermal gravimetric analysis. In addition theoretical H-1 NMR, HOMO-LUMO studies of the ligand; antimicrobial and cyclic voltammetric studies of the compounds were also carried out. In this study antioxidant and antibacterial activities of the compounds were examined via in vitro methods. (C) 2014 Elsevier B.V. All rights reserved.