Browsing by Author "Gunlu, Serhat"

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Comparison of Evolut-R 34 Mm Valve and Smaller Evolut-R Valves in Patients Undergoing Transcatheter Aortic Valve Implantation and Determination of Mild Paravalvular Leak Predictors
(Kare Publ, 2024) Demir, Muhammed; Gunlu, Serhat; Arslan, Bayram; Ertas, Faruk; Kilic, Raif; Guzel, Tuncay; Aktan, Adem
Objective: The main purpose of this study was to evaluate and compare the in -hospital, 1 -month and 1 -year post -procedure outcomes of patients treated with Evolut-R 34 mm and Evolut-R 23/26/29 mm devices. Additionally, the study aimed to identify factors that could predict the occurrence of >= mild paravalvular leaks (PVL). Methods: Between April 2015 and May 2022, 269 consecutive patients who underwent transcatheter aortic valve implantation (TAVI) with Evolut-R 34 mm (n = 66, 24.5%) and Evolut-R 23/26/29 mm (n = 203, 75.5%) devices in a single center were retrospectively analyzed. Results: Patients in the Evolut-R 34 mm group had a lower female sex ratio (16.7% vs. 66.5%, P < .001, respectively), ejection fraction (50.7 +/- 10.1% vs. 54.5 +/- 9.3%, P = .016, respectively), and mean aortic gradient (7.4 +/- 3.3 vs. 9.2 +/- 5.0, P = .026, respectively) compared to the Evolut-R 23/26/29 mm group. The groups did not exhibit any statistically significant distinctions with regard to technical success, the need for a permanent pacemaker, occurrences of stroke, major vascular complications, PVL, major adverse cardiovascular and cerebrovascular events, or mortality. Peak velocity was confirmed as a significant pre- dictor of >= mild PVL in both patient groups in the receiver operating characteristic curve analysis. In logistic regression analysis; In patients with Evolut-R 34 mm valve, pre-TAVI aortic valve peak velocity (odds ratio (OR) = 23.202; P = .019) and calcium volume 800 Hounsfield Units (mm(3)) (OR = 1.017; P < .001) were independent predictors of >= mild PVL. Conclusion: The Evolut-R 34 mm valve has shown comparable in -hospital results with smaller valve sizes. Pre-TAVI aortic valve peak velocity and calcium volume predicted >= mild PVL in Evolut-R 34 mm patients.
Comparison of Pain Levels of Traditional Radial, Distal Radial, and Transfemoral Coronary Catheterization
(Assoc Medica Brasileira, 2023) Aslan, Muzaffer; Gunlu, Serhat; Karahan, Mehmet Zulkuf; Kilic, Raif; Guzel, Tuncay; Aktan, Adem; Arslan, Bayram
OBJECTIVE: The aim of our study was to compare the traditional radial artery, distal radial artery, and transfemoral artery, which are vascular access sites for coronary angiography, in terms of pain level using the visual analog scale.METHODS: Between April 2021 and May 2022, consecutive patients from three centers were included in our study. A total of 540 patients, 180 from each of the traditional radial artery, distal radial artery , and transfemoral artery groups, were included. The visual analog scale was applied to the patients as soon as they were taken to bed. RESULTS: When the visual analog scale was compared between the groups, it was found to be significantly different (transfemoral artery: 2.7 & PLUSMN;1.6, traditional radial artery: 3.9 & PLUSMN;1.9, and distal radial artery: 4.9 & PLUSMN;2.1, respectively, p<0.001). When the patients were classified as mild, moderate, and severe based on the visual analog scale score, a significant difference was found between the groups in terms of body mass index, process time, access time, and number of punctures (p<0.001). Based on the receiver operating characteristic analysis, body mass index>29.8 kg/m2 predicted severe pain with 72.5% sensitivity and 73.2% specificity [(area under the curve: 0.770, 95%CI: 0.724-0.815, p<0.0001)].CONCLUSION: In our study, we found that the femoral approach caused less access site pain and a high body mass index predicts severe pain.
The Leuko-Glycemic Index Can Predict Ischemia in Myocardial Perfusion Scintigraphy
(AME Publishing Company, 2025) Vicdan, Şule Kılınç; Gunlu, Serhat
Background: Ischemic heart disease is frequently diagnosed with myocardial perfusion scintigraphy (MPS). The leuko-glycemic index (LGI) has also been shown to estimate myocardial ischemia (MI). The purpose of this research was to evaluate the diagnostic utility of LGI in determining MI by contrasting it with MPS. Methods: A retrospective study was performed involving patients who presented with chest pain and were referred for MPS by cardiology outpatient clinics. The study included 143 patients after applying exclusion criteria and measuring LGI. According to MPS, patients were classified into two as ischemic and non-ischemic groups. Results: The study consisted of 99 (69.2%) men and 44 women (30.8%) with a mean age of 60.33±13.83 years. Individuals were split into two categories: ischemic (n=56) and non-ischemic (n=87). No statistically significant difference exists between the groups regarding dyslipidemia (P=0.11), smoking (P=0.17), and gender (P=0.20). There were no substantial differences across the groups including laboratory parameters (P>0.05). LGI values were substantially higher in the ischemic group (P<0.001). The area under the curve (AUC) of the LGI to predict ischemic patients in the MPS was 0.752 [95% confidence interval (CI): 0.67 to 0.88; P<0.001]. The optimal cut-off value of LGI was 1,873 mg/dL·mm3 with 72% sensitivity and 70% specificity. Conclusions: LGI was an independent predictor of MI in patients with chest pain. © 2025 Elsevier B.V., All rights reserved.