Synthesis and Characterization of New Magnetic Chitosan Derivative Nanocomposite as Chemotherapy Agent

Abstract

Abstract— The purpose of this study is, suitable for carrying the mentioned therapeutic agents, to have suitable magnetic, chemical and physical properties for use in biomedical applications, magnetic targeting, synthesis and characterization of branched polymeric materials with carboxyl groups .Biocompatible and biodegradable polymers is used as Chitosan. In addition, different derivatives of these polymers were synthesized and characterized by FTIR, TEM, SEM, EDX, DLS, XPS and VSM. As a results obtained that biocompatible and biodegradable magnetic nanocomposites were of the desired size and superparamagnetism, It has been shown that synthesized polymer coated superparamagnetic nanocomposites with these properties can be used in drug targeting studies and it is hoped that this type of work will contribute to future studies.

Keywords—Chemotherapy Agent, Magnetic Nanocomposite, Chitosan Derivative, New Synthesis