Evaluation of Analytical Performance Specifications of Routine Clinical Biochemistry Tests with Biological Variation-Based Total Allowable Error (TEa) Criteria

Abstract

Evaluation of analytical performance specifications of routine clinical biochemistry tests with biological variationbased total allowable error criteria T housands of results are produced in clinical laboratories using assay procedures. These results are used for many purposes, such as group screening, diagnosis, monitoring, and differential diagnosis of diseases. Many variations are encountered in total assay procedures in laboratories, including pre-analytical, analytical, and biological variations (BVs). In order to obtain reliable results, clinical laboratories should minimize all sources of variation and manage all the testing process well. This management is applicable for all types of variation except BV