Polymorphous Low Grade Adenocarcinoma of Hard Plate

Abstract

Polymorphous low-grade adenocarcinoma (PLGA) is a rare malignancy which could usually be seen in minor salivary glands. The incidence of PGLA in all minor salivary gland tumor are 10% and 25% in all malignant minor salivary gland tumor. Salivary gland adenocarcinomas have been known as aggressive however progress of PLGA is silent and non-aggressive. Pathologic diagnosis of this tumor is so difficult because of multiple cytological variations. Besides this, treatment options and prognosis of disease is not clear and controversial. In this case diagnosis, management and treatment of PLGA of hard plate is presented with recent literature review.