Browsing by Author "Dogan, Yusuf"

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Citation - WoS: 5
Citation - Scopus: 7
Activated Carbon-Coated Iron Oxide Magnetic Nanocomposite (ionps@ctac) Loaded With Morin Hydrate for Drug-Delivery Applications
(Frontiers Media Sa, 2024) Dogan, Yusuf; Ozic, Cem; Ertas, Erdal; Baran, Ayse; Rosic, Gvozden; Selakovic, Dragica; Eftekhari, Aziz; Doğan, Yusuf; Baran, Ayşe; 06.02. Department of Plant Protection / Bitki Koruma Bölümü; 06. Faculty of Agricultural Sciences and Technologies in Kızıltepe / Kızıltepe Tarım Bilimleri ve Teknolojileri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Cancer is a major disease that affects millions of people around the world every year. It affects individuals of all ages, races, and backgrounds. Since drugs used to treat cancer cannot distinguish between cancerous and healthy cells, they cause systemic toxicity along with serious side effects. Recently, controlled drug-release systems have been developed to reduce the side effects caused by anticancer drugs used for treatment. Morin is an anticancer drug with a flavonol structure. It has been extensively researched for its antioxidant, anti-inflammatory, antitumoral, and antibacterial properties, especially found in Chinese herbs and fruits, and its multiple positive effects on different diseases. In this study, a nanocomposite with magnetic properties was synthesized by coating biocompatible activated carbon obtained using the fruits of the Celtis tournefortii plant on the surface of iron oxide magnetic nanoparticles. Characterization of the synthesized activated carbon-coated iron oxide magnetic nanocomposite was confirmed by Fourier transform infrared, scanning electron microscopy, energy-dispersive X-ray spectrometry, X-ray diffraction, dynamic light scattering, zeta potential, and vibrating sample magnetometry. The cytotoxic effects of the drug-loaded magnetic nanocomposite were examined in HT-29 (colorectal), T98-G (glioblastoma) cancer cell lines, and human umbilical vein endothelial cell (HUVEC) healthy cell line. The morin loading and release behavior of the activated carbon-coated iron oxide magnetic nanocomposite were studied, and the results showed that up to 60% of the adsorbed morin was released within 4 h. In summary, activated carbon-coated iron oxide magnetic nanocomposite carriers have shown promising results for the delivery of the morin drug.
Effect of Chemical and Organic Fertilizers on the Yield and Quality Attributes and Nutrient Composition in Lentil
(Inst Investigaciones Agropecuarias – Inia, 2025) Doğan, Yusuf; Dogan, Yusuf; Cig, Fatih; 06.02. Department of Plant Protection / Bitki Koruma Bölümü; 06. Faculty of Agricultural Sciences and Technologies in Kızıltepe / Kızıltepe Tarım Bilimleri ve Teknolojileri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
The importance of lentil (Lens culinaris Medik.) as a crop with valuable nutritional content is expected to increase with the growing global population; therefore, this research was conducted in 2019-2020 and 20202021 to evaluate the effects of organic (vermicompost, chicken manure, and farm manure) and inorganic (S and diammonium phosphate [DAP]) fertilizers on the yield and nutrient content of the lentil '& Ccedil;a & gbreve;& imath;l'. The study used no fertilizer control, chemical fertilizer (140 kg ha-1 DAP 18-46), sulfate fertilizer (30 kg S ha-1), and organic fertilizers such as chicken manure (2 t ha-1), farm manure (20 t ha-1), and vermicompost (2 t ha-1). The experiment was designed as a randomized block with three replicates. According to results, S fertilizer was found to significantly improve plant height, 1000-grain weight, grain yield, protein ratio, S and Fe content. It was predicted that farmyard manure significantly improves the grain nutrient properties (P, Cu, K, Mg, Mn, and Zn) of lentil compared to other treatments. The S fertilizer increased plant height (55.1 cm), thousand-grain weight (33.6 g), grain yield (2065 kg ha-1), and protein ratio (33.1%); additionally, farmyard manure application was found to enhance the nutrient content of lentil grains, including P (4056.7 mg kg-1), Cu (16.15 mg kg-1), K (8926.3 mg kg-1), Mg (985.1 mg kg-1), Mn (15.3 mg kg-1), and Zn (35.0 mg kg-1). It is recommended to use a combination of S fertilizer and organic fertilizers such as farmyard manure to enhance environmental sustainability, maintain soil fertility, and improve yield and nutrient content in lentil production.
Citation - WoS: 4
Evolotion Barley Genotypes in Multi-Environment Trials by Ammi Model and Gge Biplot Analysis
(Parlar Scientific Publications (p S P), 2019) Oral, Erol; Kendal, Enver; Kilic, Hasan; Dogan, Yusuf; Doğan, Yusuf; Oral, Erol; Kendal, Enver; 06.02. Department of Plant Protection / Bitki Koruma Bölümü; 16.02. Department of Seed Production / Tohumculuk Teknolojisi Bölümü; 06. Faculty of Agricultural Sciences and Technologies in Kızıltepe / Kızıltepe Tarım Bilimleri ve Teknolojileri Fakültesi; 16. School of Vocational Higher School of Kızıltepe/ Kızıltepe Meslek Yüksekokulu; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
The uniformity of genotypes are significant for crop breeding program decisions to improve new varieties. The AMMI (Additive main effects and multiplicative interaction) analysis and Genotype x Environment Interaction (GEI) is make to estimation grain yield and understands GxE interaction patterns by researches as differential ranking of variety yields in multi-environment trials. Therefore, fifteen barley advanced line and six national cultivars and four foreign varieties (registered in abroad) were used in the study. The experiments were performed according to a complete randomized block design with four replications at five environments during two years. The stability and superiority of genotypes for yield and other traits were determined using AMMI and GGE biplot analysis. Factors (G, GE, and GEI) were found to be highly significant (P < 0.01) for grain yield. AMMI analysis indicated that the major contributions to treatment sum of squares were environments (98.52%), GE (0.45%) and genotypes (1.02%), respectively, suggesting that grain yield of genotypes were effected environmental conditions. The GGE biplot indicated that PCA 1 axes (Principal component) was significant as P<0.01 and supplied to 49.36% of complete GxE interaction. The AMMI indicated that G8 and G23 desirable and stabile genotypes for grain yield in multi-environment. Moreover, E2 and E5 (irrigated environments) were high yielding, while E3 (drought stress) low yielding as forecast. On the other hand, GGE biplot indicated that three group were occurred among traits, first group (GY: grain yield, CC: crude cellulose, CD: cold damage), second group (PC:, HVV: hectoliter weight, TGW: thousand grain weight, SH: seed humidity), third group (LOD: lodging, PH: plant height, HT: heading time). Moreover: the study showed that G3, G6, G7, G8, G13 and G21 were the best genotypes both grain yield and other traits. The results of AMMI model and GGE biplot indicated that G8 is suitable to recommend for release and G23 desirable origin for yield stability and G7 valuable source for quality to use in barley breeding program.
Citation - WoS: 1
Problems Facing Teaching of Arabic in Turkey
(Cumhuriyet Univ, Fac theology, 2013) Doğan, Yusuf; Aydın, Tahirhan; 06.02. Department of Plant Protection / Bitki Koruma Bölümü; 02.02. Department of Arabic Language and Literature / Arap Dili ve Edebiyatı Bölümü; 02. Faculty of Letters / Edebiyat Fakültesi; 06. Faculty of Agricultural Sciences and Technologies in Kızıltepe / Kızıltepe Tarım Bilimleri ve Teknolojileri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
This article deals with problems encountered in teaching of Arabic language in Turkey. The problems are discussed in different categories after detailing on the importance of Arabic, the goals in teaching of Arabic, and the institutions where Arabic is taught. The problems are sometimes caused by the perspective Arabic is viewed from and sometimes by the inadequacy and unsuitability of method(s) employed by instructors. Structural differences between Arabic and Turkish languages, lack of tools-equipment, misquotation of Arabic words borrowed into Turkish, lack of proficiency of grammar in the first language, planning problems with curriculum, and unsuitability of learning environment are the problems discussed in this article.
Yarı Kurak İklim Şartlarında Ekmeklik Buğday (Triticum Aestivum L.) Çeşitlerinde Verim ve Bazı Kalite Unsurlarının Belirlenmesi
(2023) Doğan, Yusuf; Doğan, Serap; Dogan, Serap; Dogan, Yusuf; 06.02. Department of Plant Protection / Bitki Koruma Bölümü; 16.04. Department of Irrigation / Sulama Bölümü; 06. Faculty of Agricultural Sciences and Technologies in Kızıltepe / Kızıltepe Tarım Bilimleri ve Teknolojileri Fakültesi; 16. School of Vocational Higher School of Kızıltepe/ Kızıltepe Meslek Yüksekokulu; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Bu araştırma, Mardin ili ve çevresinde yaygın olarak yetiştirilen 10 ekmeklik buğday çeşidinin verim unsurları, tane verimi ve bazı kalite faktörlerinin ortaya konulması amacıyla yapılmıştır. Çalışma, Mardin-Kızıltepe koşullarında 2019-20 ve 2020-21 yetiştirme sezonlarında yağışa dayalı şartlarda Tesadüf Blokları Deneme Desenine göre 3 tekerrürlü olarak yürütülmüştür. Varyans analiz sonuçlarına göre; bitki boyu 83.7-102.0 cm; başak uzunluğu 11.0-14.2 cm; başakta tane sayısı; yüz tane ağırlığı 30.5-38.8 g; biyolojik verim 582.5-644.1; hasat indeksi %30.1-38.9; hektolitre 72.2-80.4 kg/hl; protein oranı %13.1-15.8 ve tane verimi 176.9-247.7 kg da-1 arasında değiştiği tespit edilmiştir. Çeşitlerin incelen özellikleri bakımından önemli farklılıklar ortaya çıkmıştır. Tane verimi ve yüz tane ağırlığı bakımından en yüksek değerler Ceyhan-99 çeşidinde elde edilirken, protein oranı ve hektolitre değerleri bakımından Dinç çeşidi üstün çıkmıştır. Bu çalışmada Ceyhan 99, Pehlivan ve Sgittario çeşitleri tane verimi için Mardin ili ve çevresine önerilebilir.
Citation - WoS: 7
Citation - Scopus: 7
Zinc Oxide Nanoparticles for Sustainable Agriculture: a Tool To Combat Salinity Stress in Rice ( Oryza Sativa) by Modulating the Nutritional Profile and Redox Homeostasis Mechanisms
(Elsevier, 2025) Dogan, Yusuf; Alam, Pravej; Sultan, Haider; Sharma, Renuka; Soysal, Sipan; Baran, Mehmet Firat; Faizan, Mohammad; Doğan, Yusuf; Baran, Mehmet Fırat; 06.02. Department of Plant Protection / Bitki Koruma Bölümü; 21.02. Department of Medical Services and Techniques / Tıbbi Hizmetler ve Teknikleri Bölümü; 06. Faculty of Agricultural Sciences and Technologies in Kızıltepe / Kızıltepe Tarım Bilimleri ve Teknolojileri Fakültesi; 21. Vocational School of Health Services / Sağlık Hizmetleri Meslek Yüksekokulu; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
The use of nanoparticles (NPs) as an amendment to reduce salt toxicity has gained much attention. Keeping in mind, this research work was done to evaluate the effect of zinc oxide NPs (ZnO-NPs) to mitigate the salt stress in rice (Oryza sativa) plant. Rice plants were subjected to salt stress (150 mM of NaCl) at 15 days of sowing through the soil. ZnO-NPs were characterized by Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), X-ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FTIR) and were applied foliar at concentration of 100 mg/L for five consecutive days (26-30 DAS). The results confirmed the salt toxicity and reduced shoot length (27 %), root fresh weight (31 %), SPAD chlorophyll (29 %), net photosynthetic rate (24 %), and nitrogen (N), phosphorus (P), potassium (K) and zinc (Zn) uptake by 9 %, 11 %, 13 % and 17 % respectively, while salinity increased the activity of antioxidant enzymes, proline, hydrogen peroxide (H2O2), and malondialdehyde (MDA) content in rice plants. However, in plants grown under salt stress, foliar application of ZnONPs significantly improved growth, photosynthesis, nutrient uptake and antioxidant enzymes activity. Beside, ZnO-NPs reduced salinity-induced oxidative stress by lowering H2O2 and MDA content. Therefore, our research showed that ZnO-NPs is useful and efficient in encouraging growth and lessening salinity stress in rice plants.