Dahili Tıp Bilimleri Bölümü
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Article Citation - WoS: 7Citation - Scopus: 5Sağlam çocuk polikliniğine başvuran 0-1 yaş bebeği olan annelerde depresyon taraması ve depresyonda etkili risk faktörlerini belirleme(2012) Battaloğlu İnanç, Betül; Aydemir, Nurcihan; Hatipoğlu, SamiSağlam çocuk polikliniğine başvuran 0-1 yaş bebeği olan annelerde Edinburgh Postnatal Depresyon Skalası (EPDS) ölçeğini kullanarak, depresyon oranlarını saptamayı ve etkili olan sosyodemografik faktörleri belirleyerek, elde edilen sonuçların diğer çalışmalarla korelasyonunu değerlendirmeyi amaçladık. Gereç ve Yöntem: 20 Temmuz- 20 Eylül 2007 tarihleri arasında, 0-1 yaş arası bebeği olan anneler çalışmaya dâhil edildi. 211 anne çalışmaya katıldı, postpartum sosyodemografik veri formu ile EPDS kullanıldı. Çalışmaya katılmayı kabul etmeyen 28 annenin, 7’sinde EPDS puanlaması depresyon için anlamlı değerlerde idi. Toplam 183 annenin verileri değerlendirmeye alındı. Annelerin sosyodemografik özelliklerini belirlemek için toplam 51 sorudan oluşan postpartum sosyodemografik veri formu kullanıldı. Depresyon yaygınlığını saptamak amacıyla annelere 10 sorudan oluşan EPDS ölçeği uygulandı. Değerlendirme 30 puan üzerinden yapıldı ve kesme puanı 13 ve üzeri ( ?13) olarak alındı. Bulgular: EPDS kesme puanı ?13 alınarak hesaplanan depresyon semptomatoloji skoru %30.6’dır. Çalışmaya katılan kadınların yaş ortalaması 27.5±5.45, yaş dağılımı 18 ile 43 arasında değişmektedir. EPDS puanı yüksek olanlarda evlilikten memnuniyet düzeyinin iyi olma oranı anlamlı düzeyde düşük; evlilikten memnuniyetleri orta ve kötü düzeyde olanlarda, psikiyatrik özgeçmişi olan annelerde ise EPDS puanları anlamlı düzeyde yüksek olarak saptanmıştır (p<0.01). Eşi çalışmayan, planlanmamış gebeliği olan, doğumda annede sağlık sorunu olan,gece doğum yapan annelerde EPDS puanlaması yüksek olarak görülmektedir (p<0.05). Bebekte sağlık sorunu olduğunu belirten, bebek bakımını güç olarak tarifleyenlerde, bebeğini emzirmeyen kadınlarda EPDS puanlaması istatistiksel olarak anlamlı düzeyde yüksek olarak saptanmıştır (p<0.01). Sonuç: Doğum sonrası depresyon birçok anneyi ve bebeği olumsuz etkileyen ciddi bir sorundur. Etkin bir tedavinin mümkün olmasına rağmen, olguların yarısından azı fark edilebilmektedir. Kitlelerin taranması, antenatal dönem, doğum sonrası erken dönem ve normal sağlam çocuk izlemleri döneminde, doğum sonrası depresyon tanısı koyabilme imkanını mümkündür. Toplumu temsil eden, büyük kitlelere yapılacak topluma dayalı çalışmalar ile geçerli, etkin bir doğum sonrası depresyon taramasının tanımlanmasına ve bu tip bir taramanın klinik olarak anne -bebek açısından hizmetin artırılmasına, olan etkisinin belirlenmesine gereksinim vardır.Article Evaluation of Frontal QRS-T Angle in Patients with Coronary Artery Ectasia(Sociedade Brasileira de Cardiologia – SBC, 2023) Karahan, Mehmet Zülkif; Aktan, Adem; Güzel, Tuncay; Kayan, Fethullah; Günlü, SerhatBackground: Coronary artery ectasia (CAE) is defined by focal enlargement of the coronary artery exceeding 1.5 times the adjacent normal segment. CAE can often cause arrhythmias, heart failure, sudden death, and myocardial ischemia. Ischemia due to microvascular dysfunction may be responsible for the ventricular heterogeneity in CAE. Objectives: The aim of our study was to evaluate the frontal QRS-T angle in patients with CAE. Methods: Our study included 55 patients with CAE and 50 individuals in the control group. Demographic characteristics and electrocardiographic parameters were compared between the two groups. Categorical variables were compared using the chi-square test. Continuous variables were compared using unpaired Student’s t-test. P values < 0.05 were considered statistically significant. The frontal QRS-T angle was calculated from 12-lead electrocardiograms (ECGs) using the automatic report from the electrocardiography machine. Results: The average age of patients with CAE was 63.2 ± 3.4 years, with 18 women among them. The control group had an average age of 61.1 ± 3.2 years, with 28 women included. There was no significant difference in demographic parameters between the two groups. Compared to the control group, patients with CAE had significantly wider frontal QRS-T angle (p < 0.001), as well as longer QTmax duration, p = 0.002; Tp-Te interval, p = 0.02; and QT dispersion (QTd), p = 0.04. Conclusion: The frontal QRS-T angle can be calculated easily and time-efficiently using surface electrocardiography. In this study, we showed for the first time that the frontal QRS-T angle was significantly increased in patients with CAE.Article Citation - Scopus: 3Evaluation of Frontal QRS-T Angle in Patients with Coronary Artery Ectasia(Sociedade Brasileira de Cardiologia, 2023) Karahan, Mehmet Zülkif; Aktan, Adem; Güzel, Tuncay; Kayan, Fethullah; Günlü, SerhatBackground: Coronary artery ectasia (CAE) is defined by focal enlargement of the coronary artery exceeding 1.5 times the adjacent normal segment. CAE can often cause arrhythmias, heart failure, sudden death, and myocardial ischemia. Ischemia due to microvascular dysfunction may be responsible for the ventricular heterogeneity in CAE. Objectives: The aim of our study was to evaluate the frontal QRS-T angle in patients with CAE. Methods: Our study included 55 patients with CAE and 50 individuals in the control group. Demographic characteristics and electrocardiographic parameters were compared between the two groups. Categorical variables were compared using the chi-square test. Continuous variables were compared using unpaired Student’s t-test. P values < 0.05 were considered statistically significant. The frontal QRS-T angle was calculated from 12-lead electrocardiograms (ECGs) using the automatic report from the electrocardiography machine. Results: The average age of patients with CAE was 63.2 ± 3.4 years, with 18 women among them. The control group had an average age of 61.1 ± 3.2 years, with 28 women included. There was no significant difference in demographic parameters between the two groups. Compared to the control group, patients with CAE had significantly wider frontal QRS-T angle (p < 0.001), as well as longer QTmax duration, p = 0.002; Tp-Te interval, p = 0.02; and QT dispersion (QTd), p = 0.04. Conclusion: The frontal QRS-T angle can be calculated easily and time-efficiently using surface electrocardiography. In this study, we showed for the first time that the frontal QRS-T angle was significantly increased in patients with CAEArticle Citation - Scopus: 1Investigation of the effect of comorbid psychopathologies on glycemic control in children and adolescents with type 1 diabetes mellitus(Turkish J Clinical Psychiatry, 2022) Kardaş, Burcu; Kardaş, Ömer; Demiral, Meliha; Özbek, Mehmet NuriObjective: The presence of comorbid psychiatric conditions in chronic diseases makes the management of the disease difficult. Our study, we aimed to examine the relationship between psychiatric comorbid conditions and glycemic control in children and adolescents with Type 1 Diabetes. Method: In our study, depending on the number of patients, good and moderate controls were evaluated as a single group, and HbA1c levels of 8.5 and below were included in this group. Children for Depression Inventory (CDI), Screen for Child Anxiety-Related Emotional Disorders (SCARED), Turgay Child and Adolescent Behavioral Disorders Based on DSM-IV Screening and Evaluation Scale were applied. The case and parents were evaluated with K-SADS-PL.Among 778 diabetic patients who were followed up in the pediatric endocrinology clinic, 73 cases between the ages of 8 and 17 who were followed up regularly, who did not have any comorbidities and who accepted to participate in the study were evaluated psychiatrically. Results: Of the 73 cases included in the study, 29 were accepted as the patients with good glycemic control (HbA1c <= 8.5 mg / dl), and 44 as with poor glycemic control (HbA1c>8.5mg / dl). In cases with poor glycemic control, parents' education level and income level were significantly lower, while the rate of attention deficit and hyperactivity disorder, major depressive disorder, social anxiety disorder and psychopathology was significantly higher. Discussion: The findings of this study revealed that there are many factors affecting glycemic control and there is a strong relationship between glycemic control and psychopathologies.