Meslek Yüksekokulları

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Citation - WoS: 0
Citation - Scopus: 0
Abnormal Heart Sound Detection Using Ensemble Classifiers
(Institute of Electrical and Electronics Engineers Inc., 2019) Zan, H.; Yildiz, A.; Zan, Hasan; Department of Computer Engineering / Bilgisayar Mühendisliği Bölümü
Phonocardiogram is used for ambulatory diagnostic to assess health status of heart and detect cardiovascular disease. The goal of this study is to develop automatic classification method of PCG recordings collected from different databases and recorded in a different way. For this purpose, after various time and frequency domain features are extracted from PCG recordings obtained from two databases, recordings are subjected to pre-classification in order determine which database they are obtained from. Before final classification, various time, frequency and time-frequency domain features of classified recordings are extracted. These features are fed into four different classification ensembles trained with training dataset. With final decision rule, proposed algorithm achieved an accuracy of 98.9%, a sensitivity of 93.75% and a specify of 99.5%. © 2018 IEEE.
Citation - WoS: 6
Citation - Scopus: 16
Adsorptive Performance of Magnetic Nano-Biosorbent for Binary Dyes and Investigation of Comparative Biosorption
(Springer Nature, 2019) Tarhan, T.; Tarhan, Tuba; Tural, B.; Boga, K.; Tural, S.; Department of Medical Services and Techniques / Tıbbi Hizmetler ve Teknikleri Bölümü
The individual and competitive biosorption capacities of Metanil Yellow (MY) and Reactive Black 5 (RB5) by glutaraldehyde cross-linked magnetic chitosan nanoparticles (GMCNs) were studied. Competitive biosorption of the MY and RB5 dyes by the GMCNs has never been reported previously. Fourier transform infrared technique has been used to show the biosorbed MY and RB5 dyes onto GMCNs. During the studies, various essential factors influencing the biosorption, like adsorbate concentration, pH of the solution and contact time have been monitored. The equilibrium was achieved within 17 h for single dyes and 3 h for binary mixture at pH 3. The biosorption capacities were 620 mg/g for dye MY and 2549 mg/g for dye RB5 at pH 3, 30 °C. The second-order kinetic model has good compatibility with the dynamical biosorption behavior of a single dye and binary mixture. In order to study the competition biosorption of the RB5 and MY dyes in mixture solutions, the intraparticle diffusion model was used. Competition biosorption through analysis of the intraparticle diffusion model apparently favored the RB5 dye more than the MY dye on the GMCNs in mixture solutions. The biosorbent was regenerated efficiently through the alkaline solution and was then reused ten times for biosorption–desorption cycles. © 2018, Springer Nature Switzerland AG.
Agronomic Characteristics and Yield Values of Sesame (Sesamum Indicum L.) Cultivars at Various Sowing Dates
(2023) Izgı, Mehmet Necat; İzgi, Mehmet Necat; Bulut, Burhan; Department of Medical and Aromatic Plants / Tıbbi ve Aromatik Bitkiler Bölümü
In this study, ten different sesame (Sesamum indicum L.) cultivars registered in Türkiye were investigated for their sowing dates as a second crop in the lowlands of Mardin province, in 2018 and 2019. In this study, ten different sesame cultivars were used; these were Arslanbey, Boydak, Cumhuriyet-99, Hatipoğlu, Muganlı-57, Orhangazi-99, Osmanlı-99, Sarısu, Tan-99, and Tanas. Four different sowing dates (June 5, June 15, June 25, and July 4) were examined for these cultivars. In this study, agricultural parameters such as plant height, number of lateral branches, number of capsules, seed yield, oil ratio, and oil yield of the sesame cultivars were investigated. Different sowing dates were found to have a significant effect on the sesame cultivars. The second sowing date resulted in the highest plant height, number of branches, number of capsules, seed yield, oil content, and oil yield (June 15). In terms of cultivars, the Boydak and Sarısu had the highest seed yield (2184 and 2149 kg ha-1, respectively), the Osmanlı-99 (54.6%) had the highest oil ratio, and the Sarısu and Boydak had the highest oil yield (1075 and 1062 kg ha-1, respectively). The Boydak and Sarısu cultivars are promising for high seed and oil yields in the second crop sowing, and a sowing date of June 15 is advised.
Ayvalık Tuzlasının Ağır Metal Düzeyinin Halimione Portulacoides (L.) Bitkisi Kullanılarak Belirlenmesi
(2019) Mungan Kılıç, Fatma; Ay, Güngör; Koçbaş, Fatma; Kılıç, Fatma Mungan; Department of Medical and Aromatic Plants / Tıbbi ve Aromatik Bitkiler Bölümü
Bu çalışmada, Ayvalık tuzlasında yayılış gösteren Halimione portulacoides (L.) Aellen bitkisi kullanılarak, tuzlanın Pb, Zn ve Cd düzeyleri Perkin Elmer Analyst 700 Model Alevli Atomik Absorbsiyon Spektrofotometresi (FAAS) cihazı kullanılarak belirlenmiştir. Tuzla İzmir-Çanakkale karayolunun bitişiğinde yer aldığından dolayı ayrıca karayoluna olan mesafeye bağlı değişimlerde belirlenmiştir. Bitkinin kök, gövde ve yaprak kısımları ile onun yetişme toprağı çalışmanın materyalini oluşturmuştur. Örneklemeler 2009-2010 yılları arasında, tuzlayı çevreleyen toprak set üzerinde belirlenen yedi istasyonda yapılmıştır. Her istasyondan 12 ay boyunca düzenli olarak numuneler alınmıştır. Yapılan tüm analizler sonucunda bitkide; Pb <0.001-0.977 ppm, Zn 0.099-1.650 ppm, Cd <0.001-0.102 ppm, toprakta ise Pb 0.523- 1.599 ppm, Zn 0.143-1.248 ppm ve Cd 0.006-0.432 ppm arasında olduğu belirlenmiştir. Pb ve Zn birikimi yola olan mesafeye bağlı artmış, Cd birikimi ile yola olan mesafe arasında ise net bir ilişki elde edilememiştir. Analizlerde sonuçların sınır değerlerin altında olmasının en önemli nedeni, hakim rüzgâr yönünün kuzeybatı (tuzladan karayoluna doğru) olması, tuzlanın güneyi boyunca uzanan karayolu üzerinde herhangi bir kavşak ve sinyalizasyonun bulunmaması ve yakınında kirletici özelliği olabilecek endüstri ve sanayi tesislerinin olmamasıdır.
Citation - WoS: 8
Citation - Scopus: 3
Cardioprotectiveeffectsof Hypericumtriquetrifoliumturra. Against Cyclophosphamide Related Cardiotoxicity in Rats
(2018) Çetik Yıldız, Songül; Keskin, Cumali; Ayhanci, Adnan; Şahintürk, Varol; Yıldız, Songul Cetık; Keskin, Cumali; Department of Medical Services and Techniques / Tıbbi Hizmetler ve Teknikleri Bölümü
Cyclophosphamide (CYP) is commonly used as anticancer agent but its usage is limited by cardiotoxic side effects such as dose-dependent cardiac damage, morphologically defined necrosis and bleeding. Hypericum triquetrifoliumTurra. (HT) shows anti-oxidative and anticarciogenic properties with its rich phenolic contents. The current study was designed to investigate the possible protective effect of HT on CYP-induced cardiotoxicity. Albino ratswererandomlydividedinto9groups,eachincluded7animals.Serumcreatinekinase-MB(CK-MB), malondialdehyde (MDA), aspartate transaminase (AST), glutathione (GSH), total antioxidant (TAC) and total oxidant capacity (TOC) levels were investigated. Furthermore, the cardiac tissue samples were investigated histopatologically. While the levels of serum CK-MB, MDA, AST and TOC were high, the levels of serum GSH and TAC levels were low in the CYP groups. It was also observed that CYP-induced cardiotoxicity was dose dependent. In the treatment with CYP plus HT doses there was observed an essential decrease in the CYP cardiotoxicity; decreased cell damage and oxidative stress parameters and also increased GSH and TAC levels. Based on our findings, it can be proposed that HT seed methanol extract was a strong candidate in preventing the CYP-induced cardiotoxicity.
Citation - WoS: 0
Diyarbakır Yöresindeki Bazı Tarım Topraklarının Hümik Asit İçerikleri ile Eser Elementler Arasındaki İlişkinin Çok Değişkenli İstatistiksel Yöntemlerle Değerlendirilmesi
(Kahramanmaraş Sütçü İmam Üniversitesi, 2024) Eren, Abdullah; Eren, Abdullah; Bilge, Uğur; Ceylan, Ramazan; Selçuk, Ramazan; Düz, M. Zahir; Department of Organic Agriculture / Organik Tarım Bölümü
Hümik asit (HA) ile topraktaki iz elementlerin biyoyarayışlılığı, reaksiyonları ve hareketliliği arasında önemli ilişkiler bulunmaktadır. Bu nedenle topraklar, HA uygulamalarıyla kimyasal, biyolojik ve fiziksel yönden iyileştirilmeye çalışılmaktadır. Bu çalışmada, Diyarbakır yöresinden 118 adet tarımsal toprak örneklerinin hümik asit içeriklerinin bazı iz elementlerle (Al, As, Ba, Be, Cd, Fe, Mn, Pb, Sb, Sn, Se, V ve P) olan ilişkisi çok değişkenli istatistiksel analizlerle değerlendirilmiştir. Toprak örnekleri mikrodalga yaş yakma yöntemiyle çözünürleştirildikten sonra element içerikleri ICP OES (Inductively Coupled Plasma Optical Emission Spectrometer) cihazı ile belirlenmiştir. Yöntemin doğruluğu için SRM (Standard Reference Material) olarak SRM NIST 2586 kullanılmıştır. Yapılan analiz sonucunda geri kazanım değerleri %91.6 ile %105.9 arasında bulunmuştur. Hümik asit topraklardan International Society for Humic Substances (IHSS) yöntemiyle ekstrakte edilmiş, çalkalayıcı ve santifrüj cihazı kullanılarak belirlenmiştir. Yöntemin doğruluğu için Hümik Asit Sodyum Tuzu (HA-Na) ile test edilmiştir. Elde edilen veri setine Pearson korelasyonu ve kısmi korelasyon analizi uygulanmıştır. Ayrıca çoklu regresyon, HCA (Hiyerarşik Küme Analizi) ve PCA (Principal Component Analysis) gibi çok değişkenli istatistiksel analizler uygulanmıştır. Çoklu regresyon analizi Step-wise yöntemine göre yapılmıştır. Manganese ve P (p< 0.01), HA bağımlı değişken olarak alındığında önemli bulunmuştur. Pearson korelasyon katsayısına göre toprakta HA ile As (r = -0.282**) arasındaki ilişki negatif ve anlamlı iken, Fe (r = 0.185*), Mn (r =0.273**)), Sn (r = 0.242*), Se (r = 0.325**) ve P ( r = 0.315**) gibi diğer elementlerle pozitif ve anlamlı olarak belirlenmiştir. Kümeleme ve PCA analizinde HA, P Mn ve Fe’nin aynı grupta olduğu saptanmıştır. Yapılan analizler HA’in toprağın bitki besin elementleri lehinde pozitif etki yaptığını göstermiştir.
Citation - WoS: 4
Evolotion Barley Genotypes in Multi-Environment Trials by Ammi Model and Gge Biplot Analysis
(Parlar Scientific Publications (p S P), 2019) Oral, Erol; Kendal, Enver; Kilic, Hasan; Dogan, Yusuf; Doğan, Yusuf; Oral, Erol; Kendal, Enver; Department of Plant Protection / Bitki Koruma Bölümü; Department of Seed Production / Tohumculuk Teknolojisi Bölümü
The uniformity of genotypes are significant for crop breeding program decisions to improve new varieties. The AMMI (Additive main effects and multiplicative interaction) analysis and Genotype x Environment Interaction (GEI) is make to estimation grain yield and understands GxE interaction patterns by researches as differential ranking of variety yields in multi-environment trials. Therefore, fifteen barley advanced line and six national cultivars and four foreign varieties (registered in abroad) were used in the study. The experiments were performed according to a complete randomized block design with four replications at five environments during two years. The stability and superiority of genotypes for yield and other traits were determined using AMMI and GGE biplot analysis. Factors (G, GE, and GEI) were found to be highly significant (P < 0.01) for grain yield. AMMI analysis indicated that the major contributions to treatment sum of squares were environments (98.52%), GE (0.45%) and genotypes (1.02%), respectively, suggesting that grain yield of genotypes were effected environmental conditions. The GGE biplot indicated that PCA 1 axes (Principal component) was significant as P<0.01 and supplied to 49.36% of complete GxE interaction. The AMMI indicated that G8 and G23 desirable and stabile genotypes for grain yield in multi-environment. Moreover, E2 and E5 (irrigated environments) were high yielding, while E3 (drought stress) low yielding as forecast. On the other hand, GGE biplot indicated that three group were occurred among traits, first group (GY: grain yield, CC: crude cellulose, CD: cold damage), second group (PC:, HVV: hectoliter weight, TGW: thousand grain weight, SH: seed humidity), third group (LOD: lodging, PH: plant height, HT: heading time). Moreover: the study showed that G3, G6, G7, G8, G13 and G21 were the best genotypes both grain yield and other traits. The results of AMMI model and GGE biplot indicated that G8 is suitable to recommend for release and G23 desirable origin for yield stability and G7 valuable source for quality to use in barley breeding program.
Citation - WoS: 11
Citation - Scopus: 13
Growth and Physiological Traits of Five Bread Wheat (Triticum Aestivum L.) Genotypes Are Influenced by Different Levels of Salinity and Drought Stress
(Parlar Scientific Publications (p S P), 2020) Kizilgeci, Ferhat; Kızılgeçi, Ferhat; Mokhtari, Negar Ebrahim Pour; Hossain, Akbar; Department of Seed Production / Tohumculuk Teknolojisi Bölümü
Turgor maintenance through osmotic adjustment can play a vital role in plant tolerance to drought and salinity. As per the evidence of the previous study, chemical polyethylene glycol (PEG) can create physiological drought under both salinity and water deficit conditions. Therefore, PEG is used for forcefully create osmotic stress to find out drought and salinity resistant crop cultivars at the early stage. Considering the essential role of PEG, the current observation was undertaken for understanding the effects of drought and salinity stress on several bread wheat genotypes at early developmental stage particularly during the seedling stage. Five bread wheat genotypes including four varieties such as 'Tekirdag', 'Ceyhan 99', 'Dine', 'Empire Plus' and a line 'DZ17-1' were used as seed material. To find out the genotypes which are tolerant to drought and salinity, all wheat genotypes were evaluated in four different concentration of NaCI for salinity stress (i.e., 0, 4, 8 and 12 dS/m) and four different concentration of PEG 6000 (i.e., 0, -0.2, -0.4, -0.6 MPa) for drought stress. All treatments were organised in a completely randomized design (CRD) and repeated three times. After observation, it is revealed that bread wheat cultivars 'Dine' and 'Ceyhan 99' were found tolerant of both drought and salinity stress at the seedling stage. The study also noticed that understanding of seedlings growth such as mean germination time (MGT), coleoptile length, seedling height, root length and relative water content (RWC) allow the selection of genotypes tolerance to drought and salinity. The information from the study will be helpful for examination of wheat genotypes which are suitable to cultivate under osmotic stress of both drought and salinity stress condition.
Citation - WoS: 1
Citation - Scopus: 1
Investigate Nasal Colonize Staphylococcus Species Biofilm Produced
(Journal of Clinical and Analytical Medicine, 2015) Demir, Cemil; İnanç, B.B.; Department of Medical Services and Techniques / Tıbbi Hizmetler ve Teknikleri Bölümü
Aim: 127 S.aureus and 65 CoNS strains were isolated from patients noses’. To produce a biofilm ability was investigated using three different methods. Slime-positive and negative staphylococcies’ resistance were evaluated against different antibiotics. Material and Method: Swap samples puted 7% blood agar. Staphylococcus aureus and coagulase-negative staphylococci (CoNS) isolates biofilm produced ability were investigated using Congo Red Agar (CRA), microplates (MP) and Standard Tube (ST) methods. In addition to that, presence of antibiotic resistance of the staphylococcal isolates are determined agar disc diffusion method. Results: The rate of biofilm produc-ing Staphylococcus spp strains was found to be 72.4%, 67.7%, and 62.9%, respectively with CRA, MP, and ST tests. There was no significant relationship among the tests (p>0.05). In addition, antibiotic resistance of Staphylococcus spp. against various antibiotics was also determined by the agar disk dif-fusion method. Resistance rates of biofilm positive (BP) Staphylococcus spp for penicilin G, ampicilin, amocycilin/clavulanic acid, tetracyclin, eritromycin, gentamycin, and enrofloxacin 71.7%, 69.7%, 6.2%, 20.7%, 21.4%, 1.4%, and 0.7%, respectively. Resistance rates of biofilm negative (BN) spp for 42.6%, 23.4%, 4.3%, 14.9%, 19.1%, 0.0%, 0.0% respectively. All Staphylococcus isolates were found to be susceptible to vancomycin and teicaplonin. Although BP strains antibiotic resistance rates were observed higher than BN strains. But resistance rates were not found statistically significant (p>0.05). Discus-sion: CRA is the reliablity and specifity method to determine Staphylococcus spp. biofilm produce ability. © 2015, Journal of Clinical and Analytical Medicine. All rights reserved.
Citation - WoS: 3
Investigation of Uroprotective Effects of Seed Methanol Extracts of Hypericum Triquetrifolium Turra. on Cyclophosphamide-Induced Bladder Hemorrhagic Cystitis and Nephrotoxicity in Wistar Albino Rats
(Cukurova Univ, Fac Medicine, 2020) Keskin, Cumali; Çetik Yıldız, Songül; Sahinturk, Varol; Ayhanci, Adnan; Department of Medical Services and Techniques / Tıbbi Hizmetler ve Teknikleri Bölümü
Purpose: This study investigated the possible uroprotective effects of Hypericum triquetrifolium Turra. (HT) seed methanol extracts (25,50,100 mg/kg, i.p., for 6 days) against cyclophosphamide (CYP)-induced (150 mg/kg, single dose, i.p.) acute bladder hemorrhagic cystitis (HC) and nephrotoxicity in rats. Materials and Methods: Wistar albino rats used in this study were divided into nine groups, each including seven rats. Group 1 (control) was treated with 0.5ml saline (SF) and Group 2 was treated with CYP (150 mg/kg). Groups 3, 4, 5 were treated with 25, 50, 100 mg/kg HT, respectively while groups 6, 7, 8 were treated with 25, 50, 100 mg/kg CYP + HT, respectively. Finally, Group 9 (control-2) was treated with 0.5ml-%0.2 dimethyl sulfoxide (DMSO). The serum creatinine, blood urea nitrogen (BUN), superoxide dismutase (SOD) and catalase (CAT) levels were measured in blood serum. Results: The CYP-treated rats histopathologically had mild-moderate bladder and renal injuries. The serum creatinine and BUN levels, which are the biochemical markers of renal injury, significantly increased compared to the control group. Conclusion: HT showed a protective effect on CYPrelated bladder HC and nephrotoxicity in rats by inhibiting inflammation and apoptosis.
Citation - WoS: 2
Citation - Scopus: 10
Study of Endogenous Paramagnetic Centers in Biological Systems From Different Areas
(John Wiley and Sons Inc, 2021) Keskin, Cumali; Khalilov, R.; Abiyev, H.; Kavetskyy, T.; Trubitsin, B.; Keskin, C.; Eftekhari, A.; Department of Medical Services and Techniques / Tıbbi Hizmetler ve Teknikleri Bölümü
Plant leaves (Eldar pine (Pinus eldarica M.), fig (Ficus carica L.), and olive (Olea europaea L.)), collected in territories with different ecological conditions, of the Absheron Peninsula (Azerbaijan Republic) were studied by electron paramagnetic resonance spectroscopy (EPR). The generation of nanophase iron oxide magnetic particles in biological systems under the influence of stress factors was revealed. It was found that the process of biomineralization plays a role in the formation of biogenic iron oxide magnetic nanoparticles in plants and the generation of magnetite crystals in biological tissues, and stress factors have a stimulating effect on this phenomenon. Copyright © 2021 Aygun Nasibova et al.
Citation - Scopus: 1
Synthesis and Characterization of Boron Nitride Nanotubes (Bnnts) With a New Method and Precursor Materials
(Gumushane University, 2021) Tarhan, T.; Tarhan, Tuba; Department of Medical Services and Techniques / Tıbbi Hizmetler ve Teknikleri Bölümü
Boron nitride nanotubes (BNNTs) have many application areas thanks to their superior properties such as thermal and electrical insulation, resistance to oxidation, high hydrophobicity, and high hydrogen storage capacity, as well as biocompatible properties. Therefore, new synthesis methods are being searched for BNNT with increasing interest in recent years. In this study, high purity and yield BNNTs were synthesized using precursor materials and methods that were not previously tried in the literature. A chemical vapor storage (CVD) furnace was used for the synthesis, and various parameters were changed to achieve optimum conditions. The structure of the obtained BNNTs was characterized by Fourier conversion infrared spectroscopy (FTIR), Raman spectroscopy, and a UV-visible spectrophotometer. In addition, surface morphologies were illuminated using transmission electron microscopy (TEM) and scanning electron microscopy (SEM). However, it has been observed that BNNTs obtained as a result of HR-TEM (high-resolution transmission electron microscope) analysis have a single-walled structure that is difficult to synthesize. This increases the importance and quality of synthesized BNNTs. © 2021, Gumushane University. All rights reserved.
Türkiye’nin Ekonomik Büyümesinde Sağlık Harcamalarının Etkisi: Fourier Birim Kök ve Eşbütünleşme Testinden Kanıtlar
(2023) Bayar, İlyas; Bayar, İlyas; Department of Office Services and Secreteriat / Büro Hizmetleri ve Sekreterlik Bölümü
Beşerî sermayenin ana unsurlarından biri olan sağlığın ekonomik büyüme üzerindeki etkisine ilişkin çalışmalar önemini korumaktadır. Bu çalışmada, Türkiye’de 1975-2021 dönemi esas alınarak sağlık harcamaları ve sağlık personeli sayısının ekonomik büyüme üzerindeki etkisi belirlenmeye çalışılmıştır. Çalışmada öncelikle değişkenlerin durağanlığını test etmek amacıyla amacıyla yumuşak geçişleri dikkate alan Fourier KPSS ile standart KPSS durağanlık testleri kullanılmıştır. Serilerin birinci farkları alındıktan sonra durağanlıkları sağlanmış ve ardından Fourier SHIN ve SHIN testleri ile eşbütünleşme ilişkisinin varlığı sınanmıştır. Uzun dönem katsayı tahmini için DOLS eşbütünleşme katsayı tahmincisi kullanılmıştır. Analizin son kısmında değişkenler arasındaki nedensellik ilişkisinin tespit edilmesi amacıyla Toda-Yamamoto (1995) nedensellik tespiti yapılmıştır. Analizde dâhil edilen sağlık göstergelerinin ekonomik büyümeyi pozitif etkilediği tespit edilmiştir. Ayrıca, ekonomik büyüme ile sağlık harcamaları arasında çift yönlü bir nedensellik bulgusuna ulaşılmıştır. Büyüme ve kalkınma hedeflerine ulaşmayı sağlayan sağlık alanındaki yatırımların politika yapıcılar tarafından artırılması önerilmektedir.

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