Sağlık Bilimleri Fakültesi

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Citation - WoS: 8
Citation - Scopus: 8
Analysis of bioactive compounds using LC-ESI-MS/MS, cytotoxic, antimicrobial effects, and enzyme activities from Cyclotrichium origanifolium
(Wiley Online Library, 2022) Aktepe, Necmettin; Baran, Ayşe; Atalar, Mehmet Nuri; Baran, Mehmet Fırat; Keskin, Cumali; Taşkin, Abdullah; Yavuz, Ömer; Demirtaş, İbrahim; Oğuz, Ercan; Jahan, Israt
Cyclotrichium origanifolium is a medicinal plant belonging to the Lamiaceae family. In this study, phenolic content analysis, antimicrobial effects, and cytotoxic effects of extracts of C. origanifolium were investigated. In the extracts, phenolic compound analysis by the liquid chromatography–electrospray ionization– tandem mass spectrometry method, antimicrobial effect by the minimum inhibition concentration method, and cytotoxic effect on human dermal fibroblasts (HDF), glioblastoma cell (U87), ovarian adenocarcinoma cell (Skov-3), and human colorectal adenocarcinoma cell (CaCo-2) cancer cell lines were investigated. Cytotoxicity analyses were performed by the MTT method. In addition, the GST and AChE enzyme activities of the extracts were also measured. Around 18 compounds were detected in both the methanol and ethanol extract. It was found that the best antimicrobial effect on Gram-negative Pseudomonas aeruginosa was on methanol extract, while the ethanol extract was on Candida albicans fungus (respectively, 2.50mg/ml, 5.0 μg/ml). A 500μg/ml of methanol extract has been shown to have cytotoxic activity high effect on HDF cells. GST and AChE activity were found to decrease in a concentration-dependent manner.
Citation - WoS: 26
Citation - Scopus: 25
Characterization and Comparison of Extra Virgin Olive Oils of Turkish Olive Cultivars
(Molecules, 2023) Korkmaz, Aziz
Extra virgin olive oils (EVOOs) obtained from five Turkish olive cultivars widely produced in the Aegean and Marmara regions were investigated based on their total antioxidant capacity (TAC), total phenolic content (TPC), pigment contents, fatty acid (FA) profiles, phenolic compounds (PC), volatile compounds (VC), and sensory properties. The results showed that all properties of EVOO samples were significantly affected by the olive cultivar used. The pigment contents in Ayvalık (9.90 mg·kg−1) and Uslu (9.00 mg·kg−1) oils were higher than the others (p < 0.05). The greatest values for oleic acid (74.13%) and TPC (350.6 mg·kg−1) were observed in Gemlik and Domat oils, respectively (p < 0.05). Edincik oil showed the maximum hydroxytyrosol content (48.022 mg·kg−1) and TAC value (515.36 mg TE·kg−1) (p < 0.05). The Edincik, Domat, and Uslu oils were significantly not different for the total content of C6 compounds derived by lipoxygenase, which are the main volatiles responsible for the typical aroma of EVOOs (p > 0.05). Domat oil also exhibited the highest scores for bitterness and pungency perceptions (p < 0.05). The fruitiness scores of the oil samples (except for Ayvalık oil) were close to each other, even if they were statistically different (p < 0.05). Principal component analysis (PCA) indicated that the Ayvalık oil was separated from the others due to its poor-quality characteristics. As a result, it can be stated that Domat olive oil has better quality than the others
Citation - WoS: 3
Citation - Scopus: 6
Chronic effects of maternal tobacco-smoke exposure and/or α-lipoic acid treatment on reproductive parameters in female rat offspring
(Taylor & Francis Online, 2020) Erdem Güzel, Elif; Nalan Kaya, Ahmet Tektemur, Nazife Ulker, Ahmet Yardimci, Ramazan Fazil Akkoc, Sinan Canpolat & Ibrahim Enver
Prenatal tobacco-smoke exposure negatively affects the reproductive functions of female offspring and oxidative stress plays a major role at this point. Alpha-lipoic acid (ALA), well known as a biological antioxidant, has been used as a nutritional supplement and as a therapeutic agent in the treatment of certain complications during pregnancy. We aimed to investigate the effects of maternal tobacco-smoke exposure and/or ALA administration on puberty onset, sexual behavior, gonadotrophin levels, apoptosis-related genes, apoptotic cell numbers and oxidative stress markers in the adult female rat offspring. Sprague-Dawley rats were divided into four groups; control, tobacco smoke (TS), TS+ALA and ALA groups. Animals were exposed to TS and/or ALA for 8 weeks before pregnancy and throughout pregnancy. All treatments ended with birth and later newborn female rats were selected for each experimental group. The experiment ended at postnatal day 74-77. Maternal tobacco smoke advanced the onset of puberty in the female offspring of the TS group (p < 0.05). In all treatment groups; the mean number of anogenital investigations and lordosis quality scores showed a decline, serum luteinizing hormone levels significantly increased (p < 0.05) and several histopathological changes in ovaries were observed compared to the control group. In addition, an increase in apoptotic marker levels and apoptotic cell numbers was detected in the ovaries of all treatment groups. Decreased TAS and increased TOS levels were detected in all treatment groups compared to control. These findings suggested that maternal tobacco smoke and/or ALA administration may be leading to the impaired reproductive health of female offspring. Abbreviations: ALA: alpha-lipoic acid; LH: luteinizing hormone; FSH: follicle-stimulating hormone; TAS: total antioxidant status; TOS: total oxidant status; Apaf1: apoptotic protease-activating factor 1; Casp3: caspase 3; Casp9: caspase 9; CF: cyst follicles; 4-HNE: 4-Hidroxynonenal; 8-OHdG: 8-hydroxydeoxyguanosine; TUNEL: terminal deoxynucleotidyl transferase-mediated deoxyuridine-biotin nick end labeling; ROS: reactive oxygen species; GnRHR: gonadotropin-releasing hormone receptor; HPG: hypothalamic-pituitary-gonadal; AMPK: AMP-activated protein kinase; ELISA: enzyme-linked immunosorbent assay; cDNA: complementary DNA; qPCR: quantitative real-time PCR; FC: follicular cysts; PF: primary follicle; SF: secondary follicle; GF: graafian follicle; CL: corpus luteum; DF: degenerated follicle; AF: atretic follicle.
Citation - WoS: 1
Clinical and Cytokine Profile of Children With COVID-19: A Report From Turkey
(Cureus, 2023) Unsal, Velid; Tahir Dalkıran, Emine M Kara, Velid Ünsal, Sadık Yurttutan, Sevcan İpek, Besra Dağoğlu, Yaşar Kandur
Background We aimed to analyze the expression of infection-related biomarkers and inflammatory cytokines in laboratory-confirmed cases and compare the differences between clinically severe and non-severe ones. Method We randomly selected 35 patients who were hospitalized with the diagnosis of coronavirus disease 2019 (COVID-19). Blood serum was obtained at the time of admission to the hospital, on the third to the fifth day, and at the time of discharge. Result The median age of our patients was 56.5±69.7 months (range: 1-205 months). The mean pro-B-type natriuretic peptide (pro-BNP) was significantly higher at the time of admission than on the third to the fifth day of illness. The mean pro-B-type natriuretic peptide levels at three time points were significantly higher in patients with severe cases than in mild-moderate cases. However, there was no significant difference between the clinical severity with regard to the cytokine levels at disease onset and recovery. Conclusion In the study, it was shown that cytokines play an important role in the pathogenesis of COVID-19. Therefore, it may be beneficial to use agents such as tocilizumab in the treatment.
Citation - WoS: 14
Citation - Scopus: 16
Comparison of the Breastfeeding Practices of Refugee Syrian Mothers and Native Turkish Mothers
(Mary Ann Liebert, Inc, 2020) Ertem, Meliksah; Cifci, Sema; Deger, Vasfiye Bayram
Background: The World Health Organization recommends that babies be breastfed within the first hour of delivery and that they should exclusively be given breast milk in the first 6 months. The aim of this study was to ascertain the breastfeeding behaviors of refugee Syrian women and to compare their practices with those of the native mothers of the local community. Materials and Methods: This study is a cross-sectional study. The study was conducted in a Southern city in Turkey. The questionnaire was filled by face-to-face interviews. A total of 381 refugee Syrian mothers were compared with 381 native women living in the same community. Results: A significant difference was found between the two groups regarding breastfeeding. The rate of those who initiated breastfeeding within 1 hour after delivery was 61.4% for the Syrians and 71.1% for the Turkish mothers. In addition, the rates of exclusive breastfeeding (28.1 versus 34.1) and continuing breastfeeding for 12 months (55.0 versus 63.8) were lower in the Syrian refugee mothers. Maternal age and educational level were not correlated to the breastfeeding rates. Conclusions: This study is a rare study in which refugee mothers and local mothers were compared. Forced migration and refugee status are negatively associated with breastfeeding behavior.
Citation - WoS: 46
Citation - Scopus: 52
Corrosion behavior of mild steel in 1 M HCl with Cyclotrichium niveum as a green inhibitor
(Elsevier, 2024) Yıldız, Reşit; Arslanhan, Selim; Döner, Ali; Baran, Mehmet Fırat
Recently, green inhibitors are replacing classical inhibitors in the acid cleaning industry due to very low cost, environmentally friendly and none toxic. In this study, Cyclotrichium niveum is used as a potential green corrosion inhibitor to investigate the corrosion behavior of mild steel (MS) in chloride solution using electrochemical, morphological, structural and quantum chemical methods. Fifty-three flavonoids are detected in methanol extract of cyclotrichium niveum by LC/ESI-MS/MS. While icorr values decreased, Rp and inhibition efficiencies values derived from electrochemical impedance spectroscopy (EIS) and linear polarization resistance (LPR) increased in increasing inhibitor concentrations. Maximum inhibition efficiency is found to be 97.3%, that is the almost highest value, when compared to previous studies and plant extract is classified as a mixed type inhibitor with respect to the potentiodynamic polarization (PDP). The model that best fits the experimental values is the Langmuir isotherm. The temperature effect is also studied in the range of 25–55 ○C. Higher activation energy is obtained in the presence of inhibitor, suggesting that it acts as an efficient inhibitor by forming a physical barrier to the charge and mass transfer reaction, leading to reduction in corrosion rate. Scanning electron and atomic force microscopies showed the more uniform, crack and pits free structure, confirming that there is a protective film over the MS surface for inhibited solution. XPS analysis showed the existence of C, O, and Fe atoms on the MS surface. Quantum chemical calculation manifested the adsorption mechanism associated with the electronic structure of the molecules. The findings of this work can be applicable in chemical cleaning process with acid treatment.
Citation - WoS: 5
Citation - Scopus: 5
Diagnostic Performance of Erythropoietin and Erythropoietin Receptors Levels in Children with Attention Deficit Hyperactivity Disorder
(Clinical Psychopharmacology and Neuroscience, 2021) Güngör, Meltem; Ergul Belge Kurutas, Erkan Oner, Velid Unsal, Hatice Altun, Ali Erdinc Yalin, Serap Yalin, Ozlem Bozkus, Nilfer Sahin
Objective: Attention deficit hyperactivity disorder (ADHD) is a heterogeneous, highly heritable, a common childhood neurobehavioural disorder resulting from complex gene-gene and gene-environment interactions. The erythropoietin (Epo)/erythropoietin receptors (EpoR) system turned out to have additional important functions in nonhematopoietic tissue. In this study, we aimed to investigate the levels of Epo and and EpoR, and also their diagnostic values in children with ADHD. Methods: A total of 70 children were included in the study, 35 drug-naive patients with ADHD (age: 6−12 years; male/female: 20/15) and 35 healthy controls (age: 6−12 years; male/female: 22/13). Serum Epo and EpoR levels was determined using a commercial sandwich enzyme-linked immunosorbent assay kit. Results: The results indicated that the levels of Epo decreased in patients with ADHD compared to control (p < 0.05). On the other hand, EpoR levels increased in these patients (p < 0.05). Furthermore, the ratio of Epo/EpoR was significantly lower in ADHD patients than controls (p < 0.05). Receiver operator characteristic curve analysis showed high diagnostic performance for Epo and EpoR, areas under curve were 0.980 and 1.000, respectively. Conclusion: This is the first report to investigate the association between serum Epo and EpoR levels in ADHD patients. Our results indicated that Epo may play a role in the etiology of ADHD, and Epo therapy may be beneficial in these disorders if given in addition to the routine treatment of children with ADHD. Furthermore, our results reveal possible diagnostic value of Epo and EpoR.
Citation - WoS: 5
Citation - Scopus: 6
Eating Behavior Changes of People With Obesity During the Covid-19 Pandemic
(Dove Medical Press Ltd, 2021) Deger, Vasfiye Bayram
Objective: The precautions taken during the pandemic period may cause stress-related eating behavior disorders. It was aimed to test this hypothesis, and the study was carried out to examine pandemic measures the effect of on the nutritional, depression and stress conditions of people with obesity. Methods: The individuals who participated in the study were people with obesity who received follow-up dietary therapy in a private hospital. Three separate scales were applied to the individuals, which measured the desire to overeating request, depression status and stress-fighting status. Results: This study was conducted on 368 individuals. Women had lower values of BMI (28.57 +/- 3.89 kg/cm(2)) than men ( 30.64 +/- 2.87 kg/cm(2)). When the scores of the excessive eating request scale mean scores before and during the pandemic were examined, it was seen that the scores of the individuals increased during the pandemic. In the multivariate regression model, it was seen that the increase of stress and BMI increased the FCQ score (p<0.001). Multiple regression models were created by taking into account the criteria that caused the score increase. Each variable can predict the FCQ score separately. The predictor significance order of variants on FCQ score beta values is as follows: the Patient Health Questionnaire-9 (PHQ-9) (beta=0.774), before pandemic FCQ (beta = 0.601), the Perceived Stress Scale ( PSS) (beta=-0.268), before pandemic BMIa (beta=-0.223), during pandemic BMIb (beta=0.073), and age (beta=-0.013). Conclusion: COVID-19 pandemic, making applications such as quarantine in pandemic processes has successful results in being able to combat its. However, undesirable conditions such as stress can have serious negative consequences on other health measurements. It was observed in the results of this study that excessive eating food desire developed in people with obesity.
The effect of acupressure on postoperative pain of lumbar disc hernia: A quasi-experimental study
(ELSEVIER, 2018) Tanrıverdi, Seher; Sarıtaş, Serdar
The effect of acupressure on postoperative pain of lumbar disc hernia Background: This study has been conducted for the purpose of examining the effect of acupressure on postoperatıve paın of lumbar disc hernia. Methods: This research was conducted between January 2015- July 2016 at the Neurosurgery Clinics of Turgut Özal İnönü University and Malatya State Hospital as a quasi-experimental research with pretest-posttest designs. The study population consisted of patients who were hospitalized in these clinics after operation of lumbar disc hernia. The sample group consisted of 112 patients selected with random sampling and stayed in these clinics after the power analysis (56 test, 56 control). This research data was collected between January 2016 - March 2016. Patient identification forms and visual analog scales (VAS) were used for data collection. Patient identification form was applied to the patients in the experimental group, after acupressure was applied to patients for 15-20 minutes, their level was determined with the VAS. When the acupressure was stopped, their pain was determined with the VAS. Whereas in the control group, their pain was determined with the VAS and taking the end of the time during which acupressure was applied to experimental group into consideration, their pain level was reevaluated in the 20th minute. Data were evaluated with percentage, arithmetic average, chi-square test and independent groups t test. Results: The research result showed that owing to the effect of acupressure the pain level of the experimental group decreased from 7.75±1.67 to 2.58±1.18. (p= .00). Conclusions: Hence this result suggests the effectiveness of acupressure on postoperatıve paın of lumbar disc hernia.
Citation - WoS: 5
Citation - Scopus: 7
The effect of acupressure on postoperative pain of lumbar disc hernia: A quasi-experimental study
(ELSEVIER SCI LTD, 2018) Tanrıverdi, Seher; Sarıtaş, Serdar
Lumbar disc herniation (LDH) is a disease characterized by lumbar and leg pain that occurs as a result of compression of the lumbar spinal root by the degenerated disc. The results of the study showed that 80% of humans experienced lumbar pain in any period of their lives [[1], [2], [3]]. Comprising an important part of lumbar pain; lumbar disc herniation (LDH) has an prevalence of approximately 15–56% per year [4,5]. One of the treatment methods preferred for patients diagnosed with lumbar disc herniation is surgery. Patients, who undergo surgery, experience intense pain in the early postoperative period [6]. It is known that medications are commonly used in pain control. Analgesic treatment used for pain control is the most preferred treatment method for pain relief as it has a rapid action and is administered easily [7,8]. Damages in both individual and national economy due to preferring carelessly and frequently analgesics affect negatively some physiological functionings and have negative effects such as development of addiction with the increase of dosages every time especially in cases where narcotics are preferred [9]. Thus, it is indicated that the administration of non-pharmaceutical methods by nurses to relieve the postoperative pain in patients in addition to medications increases the action of medications [8]. It is anticipated that there are numerous non-pharmaceutical methods which are efficient in pain management, such as distraction, relaxation, therapeutic touch, transcutaneous nerve stimulation (TENS), informing, hypnotherapy, acupuncture, massage, aromatherapy, music and meditation, yoga, attention-grabbing, imagination, cognitive-behavioral techniques. But, it is known that nurses do not use these methods adequately to relieve pain [10]. It may be asserted that non-pharmaceutical treatments are among independent nursing roles of professional nurses who have theoretical knowledge and problem solving ability. Nurses are required to take a role in non-pharmaceutical interventions in order to meet the health needs of individuals, families and society [11]. One of the non-pharmaceutical treatment methods used in pain relief is acupressure. Applied with touch pressuring on the acupuncture points using hands, fingers, thumbs or small beads according to the traditional Chinese medicine; acupressure is a non-pharmaceutical pain relief example that balances energy in the body [[12], [13], [14]]. Advantages of acupressure include low cost, learning convenience and non-invasive characteristics [14]. Besides, randomized clinical studies conducted to compare physiotherapy and acupressure in decreasing lumbar pain (LBP) have reveal that acupressure might be effective [[15], [16], [17]]. The use of acupressure in nursing practices by taking all its positive effects into consideration will contribute to the establishment of qualified nursing care standards.
Citation - WoS: 7
Citation - Scopus: 6
Effect of Foot Massages on Postpartum Comfort and Pain Level of Mothers after Vaginal Delivery: A Randomized Trial
(Holistic Nursing Practice, 2021) İçke, Sibel; Genç, Rabia
This study conducted on 66 mothers aimed to investigate the effect of foot massages postpartum using an introductory information form, the Postpartum Comfort Scale, the visual analog scale, and a drug follow-up card. It was concluded that foot massages positively improved comfort, reduced pain levels, and reduced unnecessary medications.
Citation - WoS: 7
Citation - Scopus: 6
Effect of Individual Psychoeducation for Primary Caregivers of Children With Autism on Internalized Stigma and Care Burden: a Randomized Controlled Trial
(Taylor & Francis Ltd, 2025) Kacan, Havva; Gumus, Funda; Deger, Vasfiye Bayram
This study aims to determine the effects of a six-week individual psychoeducation program provided to primary caregivers of children with autism on stigma and care burden. The study was conducted with 88 primary caregivers (experimental group n = 45, control group n = 43) of children diagnosed with autism. The study, prepared in an experimental design with a pretest, posttest, and control group, was performed between 17 June 2021 and 17 January 2022. In the study, a six-week individual psychoeducation was given to the experimental group. Study data were collected using a personal information form, the Internalized Stigma of Parents in Mental Illness Scale (ISPMIS), and the Caregiver Burden Scale (CBS).The mean pretest ISPMIS total score of the experimental group was X- =105.756 and the posttest total score after the psychoeducation was X- =66.489,which was a significant decrease (t = 25.571; p < 0.05). The mean CBS pretest total score of the experimental group was X- =61.067 and the posttest total score was X over bar =31.667, which was a significant decrease (t = 17.499;p < 0.05). The study revealed that the six-week individual psycho education provided to primary caregivers of children with autism decreased the participants' internalized stigma and perceived care burden.
Citation - WoS: 6
Citation - Scopus: 7
The Effect of Progressive Muscle Relaxation on Abdominal Pain and Distension in Colonoscopy Patients
(ScienceDirect, 2022) Tanrıverdi, Seher; Parlar Kılıc, Serap
Abstract Purpose This study was conducted to examine the effect of progressive muscle relaxation on abdominal pain and distension in colonoscopy patients. Design A randomized controlled experimental design. Methods The experimental group was informed about progressive muscle relaxation (PMR) and an audio recording was provided. After the colonoscopy, abdominal pain (Visual Analogue Scale (VAS) pain) and distension (VAS distension) scores were assessed, then PMR was applied for 30 minutes and pain scores were determined again. VAS pain and VAS distension scores of the control group were determined after colonoscopy and 30 minutes later. VAS abdominal pain and VAS distension scores were evaluated at the 2nd, 4th, 8th, 12th, 16th, and 24th hour after the procedure on all patients. The day after the colonoscopy, post-test data were collected. Findings The pretest VAS pain and VAS distension mean scores were similar in the intervention and control groups (P > .05). The mean VAS pain and VAS distension scores decreased significantly in the intervention group post procedure (P < .05). Conclusions PMR was determined to be effective in reducing abdominal pain and distension after colonoscopy.
Citation - Scopus: 7
The Effect of Progressive Muscle Relaxation on Abdominal Pain and Distension in Colonoscopy Patients
(ELSEVIER, 2023)
Purpose:This study was conducted to examine the effect of progressive muscle relaxation on abdominal pain and distension in colonoscopy patients. Design:A randomized controlled experimental design. Methods:The experimental group was informed about progressive muscle relaxation(PMR) and anaudio recording was provided. After the colonoscopy,abdominal pain(VisualAnalogueScale(VAS)pain) and distension (VAS distension) scores were assessed, then PMR was applied for 30 minutes and pain scores were determined again.VAS pain and VAS distension scores of the control group were determined after colonoscopy and 30 minutes later.VAS abdominal pain and VAS distension scores were evaluated at the 2nd,4th, 8th,12th,16th,and 24th hour after the procedure on all patients.The day after thec olonoscopy, post-test data were collected. Findings:The pretest VAS pain and VAS distension mean scores were similar in thei ntervention and control groups(P>.05). The mean VAS pain and VAS distension scores decreased significantly in thei ntervention group post procedure(P<.05). Conclusions:PMR was determined to be effective in reducing abdominal pain and distension after colonoscopy.
Citation - WoS: 23
Citation - Scopus: 30
Effect of seasonal variation on lipid and fatty acid profile in muscle tissue of male and female Silurus triostegus
(SPRINGER INDIA, 2016) Kacar, Semra; Bashan, Mehmet; Oymak, Seyit Ahmet
Fatty acid (FA) compositions of total lipid, phospholipid (PL) and triacylglycerol (TAG) fractions have been determined in muscle tissues of Silurus triostegus. The distributions of saturated fatty acid (SFA), monounsaturated fatty acid (MUFA) and polyunsaturated fatty acid (PUFA) proportions were found to be different among total lipid, PL and TAG fractions from lipids in muscle tissues of the male and female S. triostegus in all seasons. Triacylglycerol contained a lower proportion of PUFA and a higher proportion of MUFA and SFA than PL while PL contained higher proportion of PUFA than proportion of MUFA and SFA compared to TAG. Triacylglycerol and PL fatty acid compositions in muscle tissues of the male and female fish species were found different. The most abundant fatty acids in the investigated seasons were palmitic acid (C16:0), stearic acid (C18:0), oleic acid (C18:1 n-9), palmitoleic acid (C16:1 n-7) and docosahexaenoic acid (C22:6 n-3). It was shown that the total lipid content and FA compositions in muscle tissues of the male and female S. triostegus were influenced by reproduction period and season.
Citation - WoS: 17
Citation - Scopus: 17
Effect of therapeutic touch on daytime sleepiness, stress and fatigue among students of nursing and midwifery: A randomized sham-controlled trial
(Complementary Therapies in Clinical Practice, 2021) Utli, Hediye; Vural Doğru, Birgül; Şenuzun Aykar, Fisun
Objectives: This study was conducted to assess the effect of therapeutic touch on stress, daytime sleepiness, sleep quality and fatigue among students of nursing and midwifery. Methods: 96 students were randomized into three groups: the therapeutic touch (TT) group, the sham therapeutic touch (STT) group, and the control group. In this randomized sham-controlled study, the TT group was subjected to therapeutic touch twice a week for four weeks with each session lasting 20 min. Results: When the TT group was compared to the STT and control groups following the intervention, the decrease in the levels of stress (p < 0.001), fatigue (p < 0.001) and daytime sleepiness (p < 0.001), and the increase in the sleep quality (p < 0.001) were found to be significant. Conclusion: It was found that TT, which is one form of complementary therapy, was relatively effective in decreasing the levels of stress, fatigue and daytime sleepiness, and in increasing the sleep quality of university students of nursing and midwifery.
Citation - WoS: 4
Citation - Scopus: 6
The Effect of Virtual Rainforest and a White Noise Mobile Application on Satisfaction, Tolerance, Comfort, and Vital Signs During Arthroscopy
(Elsevier Sci Ltd, 2024) Genc, Hasan; Tanriverdi, Seher; Akar, Mehmet Sait
Background and purpose: This study was conducted to investigate the effect of Virtual Rainforest (VRF) and a White Noise (WN) mobile applications on patient satisfaction, tolerance, comfort, and vital signs during arthroscopic knee surgery. Methods: This is a randomized, controlled, interventional study. The study was completed with a total of 93 participants, 31 in the VRF group, 31 in the WN group, and 31 in the control group. Data were collected using a Patient Information Form and a Visual Analog Scale for satisfaction, tolerance, and comfort. Results: The results of study showed that there were significant increases in tolerance, satisfaction, comfort, respiratory rate, and oxygen saturation levels and significant decreases in heart rate, systolic and diastolic blood pressures in both VRF and WN groups (p < .05). In the control group, no significant difference was found between the means of the variables before and after the procedure (p > .05). Conclusion: According to the results of the study, VRF and WN applied during the arthroscopy procedure increased satisfaction, tolerance, and comfort in patients and had a positive effect on vital signs. Trial and protocol registration: ClinicalTrials.gov, NCT05992714.
Citation - WoS: 1
Citation - Scopus: 2
Effects of clinical practicum on nursing students' self-efficacy: Example of internal medicine wards
(Wiley, 2021) Kankaya, Hülya; Keskin, Hülya; Akyol, Asiye
Purpose: To evaluate the effects of clinical practicum on nursing students' self-efficacy (perceptions of confidence and importance) in internal medicine wards and the factors affecting it. Design and Methods: The single group pre-post descriptive study was conducted with 134 final-year nursing students practicing in internal medicine wards. Findings: At the beginning of the practicum, the mean score of confidence and importance subscales were 3.72 ± 0.77 and 4.25 ± 0.57, respectively. At the end of the practicum, the mean score of confidence and importance subscales were 3.91 ± 0.70 and 4.81 ± 0.76, respectively. We found that there was a significant improvement in both subscales at the end of the practicum (p < 0.05). Practice Implications: Clinical practicum positively affects students' self-efficacy in internal medicine wards
Citation - WoS: 5
Citation - Scopus: 5
The effects of different concentration methods on the chemical composition, functional and sensory attributes of molasses produced from grape (Vitis vinifera L.) juice
(SpringerLink, 2023) Korkmaz, Aziz
The efects of concentration by outdoor (OCM) and vacuum (VCM) and traditional (TCM) methods for the production of molasses from fresh grape juice (FGJ) were evaluated concerning volatile compounds, sugars, organic acids, hydroxymethylfurfural (HMF), total phenolic (TPC), total favonoid (TFC) contents, and antioxidant capacity (TAC), and sensory properties. Compared to FGJ, its molasses had lower TPC, TFC, TAC, and total organic acids and total sugars (except for the OCM) in total soluble solids (TSS). Additionally, the most of (60.7%) volatile compounds in FGJ disappeared with the production of the molasses. Moreover, all investigated features were signifcantly infuenced by the concentration method used. The TCMconcentration method markedly increased the amounts of both HMF (~ 180- and 50-fold greater than of the OCM and TCM, respectively) and total volatile furans (~20- and 3.6-fold greater than that of OCM and TCM, respectively). Additionally, this method presented the best antioxidant properties in terms of greater TPC, TFC, and TAC, whereas both TPC and TFC in the molasses produced by the OCM-method were not signifcantly diferent from those they obtained by the VCM-method. The principal component analysis (PCA) based on the chemical characteristics revealed close similarity between the OCM and VCM, even though the OCM had higher contents for sugars and organic acids. According to the sensory evaluation, there were no signifcant diferences between the scores of favor and overall acceptability for the TCM and OCM. In conclusion, an adapted the OCM-concentrating method to industrial-type can be proposed to produce high-quality molasses.
Electrocatalysis property of CuZn electrode with Pt and Ru decoration
(2021) Toprak Döşlü, Serap; DÖNER, ALİ; Yıldız, Reşit
Electrocatalysis properties strongly depend on the interaction of metallic particles and this interaction enables to change the electronic structure of alloys which enhances the catalytic activity. This property is the key factor in the developing of cost-effective and efficient Hydrogen Evolution Reaction (HER) electrocatalysts for sustainable hydrogen production. In this study, novel electrocatalysts which are decorated with Pt and Ru have been developed for HER electrocatalysis. Microscopic analysis such as scanning electron microscopy (SEM), energy dispersive X-ray (EDX), X-ray diffraction (XRD) and atomic force microscopy (AFM) are performed to determine the morphological and compositional structures. Electrocatalysis properties are evaluated by cathodic current-potential curves, electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV) in 1.0 M KOH solution. Chronoamperometry (CA) and cycle tests are used for stability/durability of electrocatalysts. Results show that a small onset potential of the porous Cu/Ni/CuZnePt is obtained for HER. Exchange current density and polarization resistance are found to be 5.39 mA cm2 and 2.0 U cm2 at overpotential of 100 mV for porous Cu/Ni/CuZnePt, respectively, indicating that Cu/Ni/CuZnePt is higher electrocatalytic properties than the others. Moreover, very low overpotentials at 10 and 40 mA cm2 are obtained on porous Cu/ Ni/CuZnePt compared with porous Cu/Ni/CuZneRu and Cu/Ni/CuZn. Porous Cu/Ni/CuZn ePt also displays excellent stability/durability in test solution. The remarkable electrocatalysis properties of porous Cu/Ni/CuZnePt can be explained due to high porous structure, leaching of Zn from the deposit, intrinsic activity of Pt as well as changing in the electronic structure. It should be considered that porous Cu/Ni/CuZnePt is of high corrosion resistance in test solution for 120 h, which makes it good candidate for HER.

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