Hemşirelik Bölümü Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12514/222

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Correlation between vitamin D status and Wechsler Adult Intelligence Scale's comprehension subtest in patient with end-stage renal diseases
(WILEY-BLACKWELL, 2016) Karaoğlan, Mehmet; Emre, Memet Hanifi; Demirtaş, Yasemin; Şahin, İdris; Taşkapan, Hülya
Aim: Cognitive decline is an important problem for individuals, as well as for the community. Increasing evidence suggests that vitamin D may play a role in maintaining cognitive function and vitamin D deficiency may accelerate cognitive decline. The aim of this study was to evaluate the status of vitamin D in chronic renal failure (CRF) patients on peritoneal dialysis (PD) and to correlate the findings with cognitive functions. Materials and methods: The study was performed in Inonu University Turgut Ozal Medical Center. Serum 25hydroxyvitamin D (25(OH)D) was measured and cognitive functions (Wechsler Adult Intelligence Scale’s (WAIS) Comprehension Subtest) tested with 51 peritoneal dialysis patients and a control group consisting of 51 healthy individuals have similar conditions with patients. Individuals with other chronic diseases and smoking and alcohol habits which may impair cognitive functions were excluded from the study. Results: Compared to each groups we found negative correlation between 25(OH)D3 levels and WAIS’s Comprehension Subtest in patient and control group. The correlation between data was evaluated with the Spearman’s test (P = 0.597, r = 0.76 and P = 0.010 r = 0.356 respectively). Conclusions: In the literature, there is no consensus on the presence of an association between vitamin D levels and cognition. In this study vitamin D levels were measured as deficiency in both groups. Further studies are needed to investigate for increasing actual knowledge about this association.
Citation - WoS: 3
Citation - Scopus: 3
Discrimination Based on Sexual Orientation “Homophobia in Healthcare Employees”: a Cross-Sectional Study
(Springer, 2025) Deger, Vasfiye Bayram; Kacan, Havva
IntroductionThe study was conducted to examine the attitudes of healthcare employees toward homosexuals and the factors affecting them, while homophobic thoughts and behaviors are based on heteronormative cultural beliefs and gender stereotypes.MethodsThis study was planned as a cross-sectional and completed with 720 healthcare employees. The Demographic Information Form and Hudson and Ricketts Homophobia Scale were used in the study. Data were collected between January 06 and January 10, 2022.ResultsThe mean homophobia total score of the employees was determined as 97,503 +/- 25,807. Homophobia levels of male healthcare employees, those who thought homosexuality is a disease, and those who stated that homosexuality can be caused by taking an example had increasing homophobia levels. The level of homophobia decreases in the presence of homosexual friends, those who can talk freely about homosexuality, and healthcare employees who support same-sex marriage.ConclusionsRecognition of individuals with different sexual orientations by healthcare employees will reduce homophobic attitudes toward these individuals. Examining the level of homophobia in healthcare institutions and ensuring that discriminatory attitudes or behaviors toward individuals from different sexual orientations are determined to be effective on the quality of healthcare and access to healthcare services.Policy ImplicationsThere is a healthcare system in which patients are generally assumed to be heterosexual; healthcare employees are not prepared to work with Lesbian, Gay, Bisexual, and Transsexual patients in general. Studies conducted on this subject indicate that more studies are needed on the subject to implement a healthcare policy focusing on sexual diversity in healthcare services and to discuss healthcare practices for the Lesbian, Gay, Bisexual, and Transsexual population.
Citation - WoS: 4
Citation - Scopus: 4
Editorial: Anxiety, burnout, and stress among healthcare professionals
(Frontiers, 2023) Bayram Değer, Vasfiye
The technology, informatics and social fields are experiencing continuous changes and developments day by day. Such changes and developments influence human life and expand the fields of research. One of these fields is the world of work life. Work life is an area where people spend a significant part of their lives by spending time and effort. The willingness of employees to make quality use of their time and labor significantly affects the efficiency obtained as a result of their work (Burton, 2010). The nature of the work requirements and the quantity of communication with other people in the workplace create challenging situations for employees. In this context, when it comes to health in work life, health workers are seen as an important sample group in terms of researching variables in work life, since their field requires qualified labor force, is vital and is a profession that constantly involves face-to-face interaction with people. The health sector is one of the sectors where employees have the most difficulties due to various factors. The health sector differs from other working environments due to the difficulty of serving patients with severe stress and the fact that employees in this sector often face stressful situations in their daily working environment.
Citation - WoS: 30
Citation - Scopus: 34
Health literacy, health perception and related factors among different ethnic groups: a cross-sectional study in southeastern Turkey
(BMC Health, 2021) Yiğitalp, Gülhan; Bayram Değer, Vasfiye; Çifçi, Sema
Background: Low levels of health literacy are associated with increased hospitalization rates, problems regarding the proper intake of medications, poor general health and increased mortality rates. It is a well-known fact that health literacy differs among ethnic groups and ethnic minorities, in particular, are known to have a low level of health literacy. The present study aimed to reveal the levels of health literacy among different ethnic groups and the affecting factors as well as the relationship between health literacy and health perceptions. Methods: This cross-sectional study was carried out with different ethnic groups (Kurdish, Arab, Turkish and Assyrian origin), between 18 and 65 years old in the province of Mardin in Turkey. The study was conducted with a total of 600 people. The European Health Literacy Scale-Turkish Adaptation (EHLS-TR) and Health Perception Scale (HPS) were used for measurement. Descriptive analysis, Mann Whitney U Test, Kruskal Wallis Test and Spearman correlation were used in the data analysis. Results: It was found that 80.7% of the participants had relatively low levels of health literacy. The lowest levels of health literacy were among those of Kurdish origin. There were correlations between sufficient levels of health literacy and several factors including being of Assyrian origin, being 50–65 years old, living in a nuclear family, being a secondary school graduate, having a high financial status, being retired, evaluating one’s own health status as good, obtaining health information from healthcare professionals, preferring to visit a state hospital to seek medical assistance first, smoking and drinking alcohol. A positive correlation was also identified between the levels of health literacy and health perception. Conclusions: It is essential to develop programs to increase health literacy for the public and, in particular, for the ethnic groups that are disadvantaged in many aspects in the context of health literacy.
Citation - WoS: 27
Citation - Scopus: 28
Novel thiadiazole-thiazole hybrids: synthesis, molecular docking, and cytotoxicity evaluation against liver cancer cell lines
(Taylor & Francis Online, 2022) Aljohani, Ghadah F.; Abolibda, Tariq Z.; Alhilal, Mohammad; Al-Humaidi, Jehan Y.; Alhilal, Suzan; Ahmed, Hoda A.; Gomha, Sobhi M.
One of the worst diseases, cancer claims millions of lives each year throughout the world, necessitating the creation of novel treatments. In this study, we designed a novel series of 1,3,4-thiadiazoles through the reaction of 2-(4-methyl-2-(2-(1-phenylethylidene)hydrazineyl)thiazole-5-carbonyl)-N-phenylhydrazine-1-carbothioamide (3) with the proper hydrazonoyl halides. Using the MTT assay, the newly synthesized thiadiazoles' growth-inhibitory potential against the liver cancer cell line HepG2-1 was assessed. In comparison to the standard drug doxorubicin (IC50 = 0.72 ± 0.52 µM), the results showed that two compounds, 16b and 21 (IC50 = 0.69 ± 0.41 and 1.82 ± 0.94 µM, respectively) had promising anticancer activity. The structural activity relationship (SAR) was investigated. In addition, molecular docking analysis onto quinone oxidoreductase2 (NQO2) receptor (PDB: 4ZVM) was investigated against the potent compounds to examine the reliability of the in vitro results. The newly prepared thiadiazole-thiazole hybrids are therefore regarded as potent anticancer drugs.
Citation - WoS: 9
Citation - Scopus: 8
Osajin from Maclura pomifera alleviates sepsis-induced liver injury in rats: biochemical, histopathological and immunohistochemical estimation
(Taylor & Francis Online, 2023) Alhilal, Mohammad; Huseyin Serkan Erol, Serkan Yildirim, Ahmet Cakir, Murat Koc, Demet Celebi, Mesut Bunyami Halici
This paper aimed to examine the impact of flavonoid osajin (OSJ) on liver damage induced by sepsis. A total of 30 male rats were divided into 5 groups (Sham, sepsis, OSJ 150, OSJ 300 and reference). During sepsis, elevated lipid peroxidation (LPO) level and catalase activity (CAT) and decreased glutathione (GSH) level and superoxide dismutase (SOD) activity were observed in hepatic tissues of sepsis group in comparison with Sham group. A strong interleukin-33 and caspase-3 expressions were detected in hepatic tissues of sepsis group. On the contrary, OSJ administration to OSJ 300 group showed a significant decrease (P < 0.001) in LPO level (176±2.926) and significant increase (P < 0.001) in GSH level (10.586±0.083) and SOD activity (29.152±0.094) in comparison with sepsis group (185.777±1.735, 8.246±0.124, 24.307±0.379 respectively). In addition, the consumption of OSJ reduced expressions of interleukin-33 and caspase-3 and improved histopathological integrity. In conclusions, OSJ has hepatoprotective effect against sepsis-induced liver injury.
Randomized controlled study:investigation of the effcet of exercise on liver function tests, fatigue and quality of life in patients with liver cirrhosis
(JOURNAL OF HEPATOLOGY, 2021) Keskin, Hülya; Türeyen, Aynur; Akarca, Ulus
Background and aims: This randomized controlled study aimed to determine the effect of the exercise program to be applied in patients with cirrhosis on the patient’s biochemistry parameters, quality of life, fatigue level, depression, and quality of sleep. Method: The study population consisted of 84 patients, including the physical exercise group (PE, n = 27), the breathing exercise group (BE, n = 29), and the no intervention group (NI, n = 28).An exercise program (5 minutes warm-up, 30 minutes walking, 5 minutes cooldown) and a 10-minute breathing exercise were requested 7days a week for 3 months in PE and BE patients, respectively. The patients were trained on how to perform the exercises and all the patients were followed up by phone calls on the exercise days and on the same days for the NI group to motivate the patients. Personal Information Form, 6-Minute Walking Test, Body Mass Index (BMI) Assessment Form, SF-36 Quality of Life Scale, Biochemistry Parameters Assessment Form, Child-Pugh Score Assessment Form, Beck’s Depression Inventory, Fatigue Severity Scale, Pittsburgh Sleep Quality Index (PSQI) were completed by face-to-face interviews at the beginning and the end of the study period. Differences between the data at the onset and at the end within the groups were tested by the Wilcoxon test. Comparisons of the differences of the groups were performed with GLM repeated measures. SPSS (IBM SPSS Statistics for Windows, Version 25.0. Armonk, NY: IBM Corp.) and R 4.0.2 software (R software, version 4.0.2, package: nparLD, R Foundation for Statistical Computing, Vienna, A

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