Yılmaz, Mehmet

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https://hdl.handle.net/20.500.12514/7725
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Dr. Öğr. Üyesi
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Department of Surgical Medical Sciences / Cerrahi Tıp Bilimleri Bölümü
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Scholarly Output

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Annals of Medical Research1
Eastern Journal of Medicine1
GORM:Gynecology Obstetrics & Reproductive Medicine1
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Now showing 1 - 4 of 4
  • Thumbnail Image
    Article
    Comparison of Early Term Results of Umbilical Arterial Blood Gas Measurement Among Uncomplicated Primiparous and Multiparous Vaginal Deliveries and Elective Cesarean Section
    (2024) Yılmaz, Mehmet; Bozbay, Nizamettin; Aboalhasan, Yasmin; Aksın, Serif; Adıguzel, Taner; Avcı, Fazil
    Aim: This study aims to investigate the early effects of the mode of delivery on the newborn in cases of non-complicated primiparous and multiparous vaginal deliveries who were admitted to the clinic in active labor, and elective cesarean section by analyzing fetal umbilical cord blood gas. Materials and Methods: In this retrospective study, 120 cases were enrolled in the study, including 40 primiparous cases, 40 multiparous cases, and 40 elective cesarean section cases. Age, pregnancy history, medical history, age of gestation at birth, delivery type, fetal Weight, APGAR score, baby gender and fetal blood gas values were statistically analyzed. Results: Statistically significant differences were found between the primiparous vaginal delivery group and the cesarean section and multiparous vaginal delivery groups in the parameters of age, gravidity, parity, and fetal Weight, with primiparous vaginal delivery showing significantly lower parameters. When compared with multiparous and primiparous vaginal delivery, a statistically significant difference was observed in APGAR 1 score, with C/S births having lower scores. In primiparous vaginal delivery, it was found that pH, pH(T), Base(Ecf)c, cHCO3(P)c, cHCO3(p,st)c, cBase(B,ox)c, and cBase(Ecf,ox)c were significantly lower compared to other groups, while only higher levels of pCO2 and mOsmc were observed. In the cesarean section group, lower levels of ctHb, Hctc, cCa, cGlu, and cLac parameters were observed compared to other groups, while the cNa level was significantly higher. Significant differences were found only between primiparous vaginal delivery and cesarean section groups in the parameter cK, with a significantly lower cK value in the C/S group. Conclusion: Primiparous pregnant women exhibited lower birth weight, lower pH in umbilical cord blood, and higher levels of pCO2, while in the cesarean group, lower APGAR score at 1 minute, lower levels of hemoglobin, calcium, glucose, lactate, and potassium were observed.
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    Master Thesis
    Birinci Haçlı Seferi ve Eyyûbî Fethinin Kudüs'teki Uygulamaları Bağlamında Kutsal Savaş ve Cihad Kavramlarının Karşılaştırılması
    (2024) Yılmaz, Mehmet; Polat, Ziya
    Dünya tarihine göz atıldığında savaşların bir nedeninin de dini hassasiyetler olduğu görülür. Savaşın müteharrik gücü olarak görülebilen din, aynı zamanda onun kimlere karşı, neden ve nasıl yapılacağını ortaya koyma noktasında da referans olmuştur. Bu bağlamda, motivasyonunu dinden alan savaşlar bazen doğrudan kutsal metinlerden referansla bazen de onun takipçileri tarafından yapılan yorumlardan hareketle belli bir yön bulmuştur. Bu tezde I. Haçlı seferi özelinde, Hristiyanların kutsal savaş algısı ile Müslümanların cihad anlayışı karşılaştırılmaya çalışılmıştır. Bu kapsamda önce kutsal savaş ve cihadın kavramsal çerçevesi çizilmiş, kavramların ve kapsamlarının yansımaları ele alınmıştır. Kavramlar açıklanırken dinlerin kutsal metinlerine, bu metinlerin yorumlarına ve ilgili din müntesiplerinin savaş tarihlerine göz atılıp konu temellendirilmeye gayret edilmiştir. Ayrıca kutsal savaşla bağlantılı bir kavram olan haklı savaş ile ilgili kavramsal ve kronolojik bir değerlendirme de yapılmıştır. Ardından önce Haçlıların Kudüs'ü ele geçirmeleri, sonrasında Eyyûbilerin şehri fethetmeleri gibi somut örnekler üzerinden bu kavramların pratikteki yansımaları ele alınmıştır. Ayrıca kutsal savaş tabirinin anlamlandırılması adına ve Haçlı seferlerinin öncülü olmasından dolayı İspanya ve çevresinin Müslümanlardan tekrar alınmasını ifade eden ve yeniden fetih anlamına gelen Reconquista, onun sebepleri ve sonuçları üzerinde de durulmuştur. Kavramların pratiğe yansımasında etkili olan ve din müntesiplerinin diğerlerine bakışını ifade eden algı da Kudüs ve Reconquista çerçevesinde tartışılmıştır. Anahtar Kelimeler: Cihad, Haçlı Seferleri, Kudüs, Kutsal Savaş, Reconquista, Selâhaddin Eyyûbî
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    Article
    Placental Vimentin Expression in Preeclampsia and Gestational Diabetes Mellitus
    (2024) Asır, Fırat; Oglak, Suleyman Cemil; Korak, Tugcan; Tas, Fatih; Yılmaz, Mehmet; Erdemcı, Fikri; Bolluk, Gokhan
    OBJECTIVE: This study investigated vimentin expression in placentas of patients with preeclampsia and gestational diabetes mellitus (GDM). STUDY DESIGN: Placentas of preeclamptic women (n=25), women with GDM (n=25), and control cases (n=25) were enrolled in this study. Placental samples were fixed in zinc-formalin and further processed for paraffin wax tissue embedding. Demographic and laboratory parameters of patients were recorded. Vimentin immune activity was analyzed in the placental sections with immunohistochemistry. Sections were imaged and analyzed under a light microscope. A semiquantitative measurement was done be- tween groups by comparing the Vimentin signal and significance was calculated. Network construction and pathway enrichment analysis were conducted using Cytoscape (v3.10.1) and ShinyGO, respectively. RESULTS: Vimentin expression was high in the placental sections of the control group. The preeclamp- sia group showed positive Vimentin expression in cytotrophoblast and syncytiotrophoblast cells and con- nective tissue of placental villi in the preeclampsia group. Vimentin expression was generally recorded as negative in placental villi, fibrinoid substances, and connective tissue cells in the GDM group. Bioinformatic analysis showed that the AGE-RAGE signaling pathway and cancer-related pathways were mainly observed in Vimentin-associated pathways, which finally activate inflammatory pathways in both preeclampsia and GDM. CONCLUSION: Vimentin expression patterns in placental tissue sections reveal nuanced regulatory mechanisms, emphasizing the need for further exploration into the functional roles of vimentin in pla- cental physiology and pathology.
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    Article
    Thyroid Function Tests and Thyroid Antibody Tests in Ectopic Pregnancies: a Prospective Cohort Study
    (Yuzuncu Yil Universitesi Tip Fakultesi, 2024) Yoldas, Adem; Batmaz, İbrahim; Balsak, Deniz; Aksin, Şerif; Yılmaz, Mehmet; Aboalhasan, Yasmin
    Thyroid hormone levels have been observed to induce structural changes in different regions of the fallopian tube. This study aimed to investigate the impact of thyroid hormones on ectopic pregnancy. In pursuit of this objective, 31 patients with ectopic pregnancy were monitored at Siirt University Training and Research Hospital between July 2022 and December 2022. Additionally, a total of 31 patients with normal first -trimester pregnancies, matched for age, parity, and gestational week, were included i n the control group. Various parameters, including patient age, pregnancy history, medical history, treatment methods, clinical and demographic data, TSH, fT3, fT4, TT3, TT4, Thyroglobulin, Anti-thyroglobulin Antibody, TSH receptor antibody (TrAB), Anti -Peroxidase Antibody, Anti-Tyroglobulin Antibody, hemogram, biochemistry, CRP, and sedimentation values, were compared.Clinical Trials no: NCT05446012 Statistically significant differences were noted in Free T3 (p = 0.011) and thyroglobulin (p = 0.018) values between the ectopic pregnancy and control groups. Subsequent ROC analysis was conducted for the significant parameters, determining the AUC (Lower and Upper Bound), sensitivity, specificity, and cut -off values for each parameter. Multivariate logistic regression analysis followed, wherein the \"backward stepwise model\" was applied to the Free T3 parameter. The apparent parameter indicating an increased risk in the disease was Free T3, with a 4.2 -fold increase and a 95% CI of [1.3-13.5]. Lower Free T3 levels were associated with an elevated risk of ectopic pregnancy. The assessment of Free T3 levels during pre-pregnancy counseling may aid in identifying pregnant women at risk of ectopic pregnancy.