Development of Malaria Diagnosis With Convolutional Neural Network Architectures: a Cnn-Based Software for Accurate Cell Image Analysis

Abstract

This study emphasizes that early diagnosis and treatment of malaria is critical in reducing health problems and mortality from the disease, especially in developing countries where the disease is prevalent. Malaria is a potentially fatal disease transmitted to humans by mosquitoes infected by a blood parasite called Plasmodium. The traditional method of diagnosis relies on experts examining red blood cells under a microscope and is inefficient as it is dependent on expert knowledge and experience. Nowadays, machine learning methods that provide high accuracy are increasingly used in disease detection. In this paper, a Convolutional Neural Network (CNN) architecture is proposed to distinguish between parasitized and non-parasitized cells. In addition, the performance of the proposed CNN architecture is compared to pre-trained CNN models such as VGG-19 and EfficientNetB3. The studies were carried out using the Malaria Dataset supplied by the National Institute of Health (NIH), and our proposed architecture was shown to function with 99.12% accuracy. The results of the study reveal that it is effective in improving the accuracy of cell images containing Plasmodium. In addition, a software that predicts whether cell images are noisy or not has been developed. © 2025 by authors and Galileo Institute of Technology and Education of the Amazon (ITEGAM).