Rektörlüğe Bağlı Bölümler

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Antioxidant and Antimicrobial Capacity of Quinic Acid
(Bitlis Eren Üniversitesi Fen Bilimleri Dergisi, 2022) Ercan, Leyla; Doğru, Mehmet
Recently, agents with natural antioxidant and antimicrobial properties have been popularly studied. For this purpose, phenolic compounds, terpenes, and organic acids are examined for their antioxidant and antimicrobial properties. Of these, organic acids are increasingly being used in pharmacology, medicine, food, and industry. Quinic acid is a natural organic compound found in many edible fruits and plants. In this study, the antioxidant effect of quinic acid, which has the structure of cyclohexane carboxylic acid, was determined in vitro using seven different methods (DPPH, ABTS, CUPRAC, DMPD, FRAP, Fe3+ reduction, and Total antioxidant method). In addition, its antimicrobial effect on fungi (C. albicans), gram-positive bacteria (S. aureus, S. pyogenes), and gram-negative bacteria (E. coli, K. pneumoniae, and P. aeruginosa) were determined by the disk diffusion method. As a result, it was found that quinic acid has broad-spectrum antimicrobial properties, but its antioxidant properties are too low to be highlighted. While its antimicrobial activity was quite good, especially on K. pneumoniae E. coli, S. aureus, S. Pyogenes, and P. aeruginosa, it did not show any effect on C. albicans. Although the antioxidant property of quinic acid is low, it showed more antioxidant properties in the DMPD method, which is one of these methods, because it dissolves very well in water.
Citation - WoS: 4
Citation - Scopus: 5
Corn processing by pulsed electric fields with respect to microbial inactivation and improvement of seed vigour
(Elsevier Sci Ltd, 2024) Evrendilek, Gulsun Akdemir; Atmaca, Bahar; Uzuner, Sibel
Pulsed electric field (PEF) treatment of corn grains to improve seed vigour and inactivation of endogenous microflora by energies ranging from 1.20 to 28.8 J were applied to determine effectiveness of applied energies on germination rate (GR), normal seedling rate (NSR), electrical conductivity (EC), ability to germinate under salt (100- and 200 mM salt) and cold (at 10 degrees C for 7 days and at 25 degrees C for 5 days) stresses. Moreover, the effect of PEF treatments was further investigated for the inactivation of total aerobic mesophilic bacteria (TAMB), total mold and yeast (TMY), and inactivation rate (%) of Aspergillus parasiticus. Increased energy provided 11.10 % increase in GR, 21.22 % increase in NSR, 95.50 % increase in germination at 10 degrees C for 7 days. Germination under stress conditions revealed 32.53 %, 68.35 %, and 76 % increase in germination at 25 degrees C for 5 days, under 100 mM- and 200 mM NaCI salt stresses. Inactivation on the mean initial TAMB and TMY were approximately 9.25 and 7.93 log, respectively, with 63.33 +/- 0.22 % reduction in A. parasiticus culture. PEF treated corn seedlings had stronger and taller body formation with stronger roots. The most optimal processing parameters were detected as 300 Hz, 28.80 J, and 19.78 sec. PEF treatment carries a high potential to improve corn vigour with inactivation of surface microflora.
Citation - WoS: 3
Citation - Scopus: 3
Genetic Diversity and Population Structure of Anatolian Hair Goats, an Ancient Breed
(Copernicus Gesellschaft Mbh, 2024) Akçay, Ahmet; Gunduz, Zuhal; Ata, Nezih; Yilmaz, Onur; Cemal, Ibrahim; Konyali, Aynur; Senyuz, Hasan Huseyin; Rectorate / Rektörlük
This study aimed to investigate the genetic characterization and diversity of Hair goats from 10 regions using 20 microsatellite markers. A total of 522 alleles were observed. The INRA0023 locus exhibited the greatest number of alleles (48), while the DRBP1 locus had the highest effective allele number (16.27), and the BM1818 and DRBP1 loci had the highest polymorphic information content value (0.94). The expected heterozygosity value ranged from 0.85 (ILSTS011) to 0.94 (BM1818, SRCRSP15, and DRBP1). The Hair goat populations in Konya and Hatay displayed the lowest and highest allele numbers, with values of 10.40 and 16.25, respectively. The fixation index (FIS) values are significant in defining population structures and determining the extent of heterozygosity losses. The FIS values exhibited a range of 0.031 in Mu.gla to 0.226 in Burdur. A total of 107 unique alleles were identified in Hair goat populations. However, it is noteworthy that, out of all the alleles, only 25 had a frequency exceeding 5 %. The results indicate that the microsatellite markers utilized demonstrate sufficient levels of polymorphism, making them appropriate for efficiently investigating the genetic variability of Hair goat populations.
İLK HAÇLI SEFERİNE KARŞI ULEMA SINIFINDAN TEPKİLER
(2020) Hilal AĞALDAY
Papa Urban’ın çağrısı ile 1095’te başlayan Haçlı seferleri, ilk aşamada İslam dünyasında yerel ve cılız sayılabilecek bir direnişle karşılaşmıştır. Gelişmelerden rahatsızlık duyan bazı İslam âlimleri bu durumu önce şiirleriyle daha sonra hilafetin merkezi olan Bağdat’ta fiili protesto eylemlerinde bulunmak suretiyle, ümmet bilincini harekete geçirmeye çalışmışlardır. Bu çalışmada Müslümanların şehir olarak üçüncü kutsalı kabul edilen Kudüs’ün Haçlı istilasına uğramasına ve gerek bu istilada ve gerekse diğer İslam topraklarında yaşanan soykırım mesabesindeki katliama sessiz kalan İslam dünyasını uyandırma çabası güden bazı alimlerin yazdıkları şiir, kitap ve fiili protestolarına yer verilmiştir. Öz olarak çalışmamız; Birinci Haçlı seferi sonrası İslam dünyasında yaşanan umursamazlık ve iç çatışmalara karşı, ulemanın hem fiili hem de yazılı metinlerle verdiği tepkiyi kapsayacaktır. The Crusades, which started in 1095 with the call of Pope Urban, encountered a resistance that could be considered local and undersized in the Islamic world. Some Islamic scholars, who are uncomfortable with this, have attempted to mobilize this awareness with their poems, first by going to Baghdad, which is the center of the caliphate, and by carrying out actual protest actions. In this study, the poems, books and de facto protests written by Muslims who tried to wake up the Islamic world that remained silent in the Crusader invasion of Jerusalem, which was accepted as the third blessing of the city, and in the genocide struggle both in this invasion and in other Islamic lands, were included. In essence, our work; It will include the reaction of the ulema to both the actual and written texts against the indifference and internal conflicts in the Islamic world after the First Crusade.
Citation - WoS: 2
Citation - Scopus: 1
Investigation of Antibacterial and Antifungal Efficacy of Zinc and Silver Nanoparticles Synthesized From Nasturtium Officinale
(Ankara Univ, Fac Agriculture, 2023) Ercan, Leyla
Nanoparticles are nano -sized materials that can be widely used in fields such as medicine, pharmacology, and industry. The use of natural and easily available materials in nanoparticle synthesis is preferable for economic reasons. Plants are extremely suitable for the synthesis of nanoparticles due to their wide availability and the large number of components they contain with various properties. For this purpose, silver nanoparticles and zinc nanoparticles (AgNPs and ZnNPs), two different nanoparticles were synthesized from an edible plant, watercress (Nasturtium officinale). Scanning electron microscopy, scanning electron microscopy -energy dispersive X-ray, UV-VIS spectroscopy, X-ray diffraction (XRD), and fourier transform infrared spectrophotometer (FTIR) analyses of these nanoparticles were performed. In addition, the antimicrobial effects of these synthesized nanoparticles were determined using the disk diffusion method. The nanoparticles obtained from Nasturtium officinale were effective on Gram-negative bacteria (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa), Gram-positive bacteria (Staphylococcus aureus, Streptococcus pyogenes), and fungi (Candida albicans). In particular, AgNPs with broad-spectrum antimicrobial activity were obtained from the watercress. While ZnNPs showed inhibition effects of 49% on K. pneumoniae, 51% on S. aureus, and 62% on C. albicans, AgNPs showed inhibition effects of 93% on P. aeruginosa, 87% on S. aureus, 81% on E. coli, 80% on C. albicans, 72% on K. pneumoniae, and 56% on S. pyogenes. The results show that Nasturtium officinale can be used effectively in the production of new biotechnological products, particularly ones with antimicrobial properties.
MARDİN ARTUKLU ÜNİVERSİTESİ KÜTÜPHANE YÖNERGESİ
(2018) Mardin Artuklu Üniversitesi, Kütüphane ve Dokümantasyon Daire Başkanlığı
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