PubMed İndeksli Yayınlar Koleksiyonu
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Browsing PubMed İndeksli Yayınlar Koleksiyonu by Author "09.02. Department of Midwifery/ Ebelik Bölümü"
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Article Citation - WoS: 17Citation - Scopus: 15Alpha-lipoic acid may ameliorate testicular damage by targeting dox-induced altered antioxidant parameters, mitofusin-2 and apoptotic gene expression(Andrologia, 2021) Erdem Güzel, Elif; Kaya Tektemur, Nalan; Tektemur, Ahmet; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiIn the study, the ameliorating effects of alfa lipoic acid (ALA) against doxorubicin-induced testicular apoptosis, oxidative stress and disrupted mitochondrial fusion were investigated in male rats. Rats were divided into four groups as control, doxorubicin (DOX), DOX + ALA and ALA. A single dose of 15 mg/kg DOX was administered i.p to the DOX and DOX + ALA groups. 50 mg/kg ALA was given to the DOX + ALA and ALA groups by oral gavage every other day. After 28 days, rat testes and serum samples were collected and analysed. Administration of DOX alone caused a decrease in body and relative testicular weights, seminiferous tubule diameter and germinal epithelium thickness, Johnsen's score and serum testosterone levels. DOX treatment led to severe testicular damage such as tubular degeneration, and atrophic tubules. Also, the activities of superoxide dismutase and glutathione peroxidase were reduced, while the level of malondialdehyde was increased in the testis. The mRNA levels of apoptotic-related genes (CASP3, TP53, BAX, BCL2) and apoptotic index were increased, while mitofusin-2 decreased. DOX caused an increase in CASP3 and a decrease in mitofusin-2 immunoreactivities. Treatment with ALA markedly improved all of DOX-induced biochemical, histochemical and molecular alterations in rat testis. Consequently, ALA has a therapeutic role in ameliorating DOX-induced testicular damage in rats.Article Citation - WoS: 9Citation - Scopus: 12The antioxidant and anti-apoptotic potential of Pleurotus eryngii extract and its chitosan-loaded nanoparticles against doxorubicin-induced testicular toxicity in male rats(Wiley, 2021) Erdem Güzel, Elif; Acay, Hilal; Yıldırım, Ayfer; Acay, Hilal; Yıldırım, Ayfer; 09.02. Department of Midwifery/ Ebelik Bölümü; 09.03. Department of Nutrition and Dietetics/ Beslenme ve Diyetetik Bölümü; 21.02. Department of Medical Services and Techniques / Tıbbi Hizmetler ve Teknikleri Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 21. Vocational School of Health Services / Sağlık Hizmetleri Meslek Yüksekokulu; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiThis study was conducted to evaluate the protective role of Pleurotus eryngii extract (PE) and Pleurotus eryngii extract-loaded chitosan nanoparticles (PE-CSNP) against doxorubicin (DOX)-induced testicular toxicity in rats. Male rats were divided into six groups: control (DMSO/ethanol), PE (200 mg/kg PE), PE-CSNP (30 mg/kg PECSNP), DOX (10 mg/kg DOX, a single dose, i.p), DOX+PE (10 mg/kg DOX+200 mg/ kg PE) and DOX+PE-CSNP (10 mg/kg DOX+30 mg/kg PE-CSNP). PE and PE-CSNP were administered by oral gavage every other day for 21 days. DOX-treated rats showed histopathological impairment compared with the control group. There was an increase in the apoptotic index, caspase 3 (CASP3), BCL2-associated X apoptosis regulator (BAX), dynamin-related protein 1 (DRP1) expression and total oxidative status (TOS) in the DOX group, while mitofusin-2 (MFN2), total antioxidative status (TAS) and serum testosterone levels of the DOX group reduced when compared with the other groups. PE and PE-CSNP treatments provided significant protection against DOX-induced oxidative stress by reducing TOS levels and increasing TAS levels. CASP3, BAX, apoptotic index and DRP1-MFN2 expressions were restored by PE and PE-CSNP. However, the PE-CSNP showed higher antioxidant and anti-apoptotic efficacy compared with PE. Thus, our results provide evidence that CSNP and PE could synergistically have a potent antioxidant and anti-apoptotic therapy against DOX-induced testicular damage in male rats.Article Citation - WoS: 1Citation - Scopus: 1Body Image, Self-Esteem, and Attitudes Toward Sexuality in Older Adults With Chronic Illnesses(Springer/Plenum Publishers, 2025) Ozbay, Hediye; Filoğlu Ersü, Nilay; Utli, Adil; Ersu, Nilay Filoglu; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiThis study aimed to examine the effect of the association between body image and self-esteem levels on attitudes toward sexuality in older adults with chronic illnesses. The research was descriptive, cross-sectional, and correlational. The study sample comprised 1,004 people over the age of 65 who visited family health centers in a province in the east of T & uuml;rkiye. The Older Person's Description Form, the Body-Cathexis Scale, the Rosenberg Self-Esteem Scale Short Form, and the Sexual Attitude Scale for Elderly People were used for data collection. For the data analysis, Pearson's r correlation test, simultaneous multiple linear regression, and binary logistic regression were employed. The mean age of the participants was 69.97 +/- 5.74 years, and 66.9% were between 65 and 74 years of age. Furthermore, 53.8% of the participants were male and 56.2% had two chronic illnesses. It was found that the participants' age, body image, and self-esteem explained 84% of the total variance in their permissive attitudes toward sexuality. Furthermore, as the age of the older adults with chronic illnesses increased, there were negative effects on their permissive attitudes toward sexuality. However, as their body image and self-esteem levels improved, there was a positive effect on their permissive attitudes toward sexuality. These findings will be of benefit in encouraging and developing sexual health in older adults with chronic illnesses.Article Citation - WoS: 8Citation - Scopus: 9Carbamazepine-induced renal toxicity may be associated with oxidative stress and apoptosis in male rat(Taylor & Francis Online, 2021) Erdem Güzel, Elif; Kaya Tektemur, Nalan; Tektemur, Ahmet; Etem Önalan, Ebru; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiCarbamazepine (CBZ) is the antiepileptic drug used in epilepsy and some psychiatric disorders. Besides its widely used, many adverse effects have been reported including hematotoxicity, hepatotoxicity, endocrine disorders, and testicular damages due to oxidative stress. However, the role of CBZ on renal toxicity is not fully known. In this study, we attempted to explain the connected mechanisms by focusing on the metabolism of CBZ-induced renal toxicity in rats. Twenty male Wistar-Albino rats were randomized into 2 groups (n = 10); control (1 mL/day distilled water, orally) and CBZ (25 mg/kg/day CBZ, orally) groups. After 60 days, TAS (total oxidant status) and TOS (total oxidant status) levels, histopathological features, some genes involved in apoptosis, 8-hydroxy-2-deoxyguanosine (8-OHdG) activity, and apoptotic cells were assessed of kidney tissue. The oxidative stress index (OSI) was measured from TAS and TOS levels. TOS levels and OSI significantly increased, while TAS levels decreased in the CBZ group relative to the control group. Histopathological observations, Caspase-3 (Casp3), Poly [ADP-ribose] polymerase-1 (PARP-1), 8-OHdG immunoreactivities, and apoptotic cells markedly raised in the CBZ group compared with the control group. Also, mRNA expression of Cytochrome c (Cytc) and CASP3 significantly increased in the CBZ group compared to the control group. In conclusion, long-term use of CBZ may promote renal damage in rats by inducing oxidative stress and apoptosis.Article Citation - WoS: 3Citation - Scopus: 4Chronic effects of maternal tobacco-smoke exposure and/or α-lipoic acid treatment on reproductive parameters in female rat offspring(Taylor & Francis Online, 2020) Erdem Güzel, Elif; Nalan Kaya, Ahmet Tektemur, Nazife Ulker, Ahmet Yardimci, Ramazan Fazil Akkoc, Sinan Canpolat & Ibrahim Enver; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiPrenatal tobacco-smoke exposure negatively affects the reproductive functions of female offspring and oxidative stress plays a major role at this point. Alpha-lipoic acid (ALA), well known as a biological antioxidant, has been used as a nutritional supplement and as a therapeutic agent in the treatment of certain complications during pregnancy. We aimed to investigate the effects of maternal tobacco-smoke exposure and/or ALA administration on puberty onset, sexual behavior, gonadotrophin levels, apoptosis-related genes, apoptotic cell numbers and oxidative stress markers in the adult female rat offspring. Sprague-Dawley rats were divided into four groups; control, tobacco smoke (TS), TS+ALA and ALA groups. Animals were exposed to TS and/or ALA for 8 weeks before pregnancy and throughout pregnancy. All treatments ended with birth and later newborn female rats were selected for each experimental group. The experiment ended at postnatal day 74-77. Maternal tobacco smoke advanced the onset of puberty in the female offspring of the TS group (p < 0.05). In all treatment groups; the mean number of anogenital investigations and lordosis quality scores showed a decline, serum luteinizing hormone levels significantly increased (p < 0.05) and several histopathological changes in ovaries were observed compared to the control group. In addition, an increase in apoptotic marker levels and apoptotic cell numbers was detected in the ovaries of all treatment groups. Decreased TAS and increased TOS levels were detected in all treatment groups compared to control. These findings suggested that maternal tobacco smoke and/or ALA administration may be leading to the impaired reproductive health of female offspring. Abbreviations: ALA: alpha-lipoic acid; LH: luteinizing hormone; FSH: follicle-stimulating hormone; TAS: total antioxidant status; TOS: total oxidant status; Apaf1: apoptotic protease-activating factor 1; Casp3: caspase 3; Casp9: caspase 9; CF: cyst follicles; 4-HNE: 4-Hidroxynonenal; 8-OHdG: 8-hydroxydeoxyguanosine; TUNEL: terminal deoxynucleotidyl transferase-mediated deoxyuridine-biotin nick end labeling; ROS: reactive oxygen species; GnRHR: gonadotropin-releasing hormone receptor; HPG: hypothalamic-pituitary-gonadal; AMPK: AMP-activated protein kinase; ELISA: enzyme-linked immunosorbent assay; cDNA: complementary DNA; qPCR: quantitative real-time PCR; FC: follicular cysts; PF: primary follicle; SF: secondary follicle; GF: graafian follicle; CL: corpus luteum; DF: degenerated follicle; AF: atretic follicle.Article Citation - WoS: 3Citation - Scopus: 3Chronic Maternal Tobacco Smoke Exposure and/or Alpha-Lipoic Acid Treatment Causes Long-Term Deterioration of Testis and Sexual Behavior in Adult Male Rats(Elsevier, 2020) Erdem Güzel, Elif; Ramazan Fazil Akkoc, Ahmet Tektemur, Nazife Ulker, Nalan Kaya Tektemur, Elif Erdem Güzel, Sinan Canpolat, Ibrahim Enver Ozan; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiBackground: Tobacco use during pregnancy is known to have several negative effects on the offspring's reproductive health in the long term. The use of alpha-lipoic acid (ALA) as a dietary supplement during pregnancy has increased greatly in recent years and has been known to have positive effects on various pregnancy outcomes including miscarriage, diabetic embryopathy, preterm delivery, and congenital malformations. Aim: To evaluate the effects of tobacco smoke exposure (TSE) on sexual behavior, reproductive parameters, and testicles in adult male rats and to reveal the possible role of ALA administration on these parameters. Methods: Pregnant rats (n = 7 per group) were treated with tobacco smoke (TS), ALA (20 mg/kg), and TS + ALA for a total of 11 weeks. The following parameters were compared with 8 control rats: puberty parameters, sexual behavior; levels of serum gonadotropins and testosterone, total antioxidant status, and total oxidant status; the expression of the apoptotic protease-activating factor-1 and caspase 9 mRNA levels in the testis; and assessment of immunohistochemistry and terminal deoxynucleotidyl transferase dUTP nick end labeling assay of testis. Main Outcome Measure: Sexual behavior, changes in puberty parameters, and hormonal and genetic alterations were the outcomes analyzed in this study. Results: Maternal TSE caused a significant decrease in the number of intromissions compared to the control group. Similarly, ALA decreased erectile function in sexual behavior by decreasing the number of intromissions and intromission ratio in the ALA group compared to the control group. In addition, TSE and ALA treatment caused an impairment of some consummatory sexual behaviors. Also, in parallel with this inhibitory effect, the age of pubertal onset was significantly delayed in the TS + ALA group compared to other groups. Also, histopathological changes in testicular tissue, oxidative stress markers, apoptotic index, and mRNA levels of apoptosis-related genes increased in all treatment groups. Clinical Implications: The use of ALA and/or tobacco products during pregnancy may adversely affect the reproductive health of male newborns in the long term. Strengths & Limitations: To the best of our knowledge, this study is the first to show the effects of maternal ALA treatment and/or TSE on the sexual behavior and reproductive parameters in male rats; however, the study is based on an animal model, and the present findings partially reflect the characteristics of human sexual behavior. Conclusion: Maternal TSE and/or ALA treatment may impair sexual behavior in adulthood in male rats because of testicular damage caused by oxidative stress during gonadal development. Yardimci A, Akkoc RF, Tektemur A, et al. Chronic Maternal Tobacco Smoke Exposure and/or Alpha-Lipoic Acid Treatment Causes Long-Term Deterioration of Testis and Sexual Behavior in Adult Male Rats. J Sex Med 2020;17:1835–1847.Article Citation - WoS: 3Citation - Scopus: 4The combination of N-acetylcysteine and cyclosporin A reduces acetaminophen-induced hepatotoxicity in mice(Ultrastructural Pathology, 2021) Erdem Güzel, Elif; Kaya Tektemur, Nalan; Gül, Mehmet; Tektemur; Özcan Yıldırım, Sena; Kavak Balgetir, Merve; Ozan Kocamüftüoğlu, Gonca; Yalçın, Tuba; Ozan, & İbrahim Enver; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiAcetaminophen (APAP)-induced hepatotoxicity is the most common cause of acute liver failure in worldwide. N-acetyl cysteine (NAC) is used as the APAP antidote. Cyclosporin A (CsA) is suppressed mitochondrial damage by binding cyclophilin, a mitochondrial pore transport component. The study aimed to evaluate the effects of NAC, CsA, and NAC+CsA treatments on APAP-induced hepatotoxicity in mice. Mice were randomly divided into five groups (n = 6). 400 mg/kg/ip/single dose APAP, 1200 mg/kg/i.p/single dose NAC and 50 mg/kg/i.p/single dose CsA were performed. Light and electron microscopic alterations were investigated in liver samples. Levels of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) and liver glutathione (GSH) were analyzed. 3-nitrotyrosine and cytochrome c immunoreactivities were evaluated in liver tissue. Here, we found that APAP leads to histopathological and ultrastructural changes in mice liver. Also, APAP increased cytochrome c and 3-nitrotyrosine immunopositive staining. Besides, a significant decrease in liver GSH and an increase in serum AST and ALT levels were detected in the APAP group. Interestingly, NAC+CsA treatment improved histological alterations, cytochrome c, and 3-nitrotyrosine immunoreactivities and liver GSH, serum AST/ALT levels caused by APAP. We suggest that the combination of NAC and CsA reduces acetaminophen-induced hepatotoxicity in mice.Article Citation - WoS: 1A Cross-Sectional Study of Emergency Care Services During the Covid-19 Pandemic: A Multicenter Study of Healthcare Staff Perspectives(Springernature, 2024) Bütün, Ahmet; Yeşil, Yeşim; 09.01. Department of Nursing / Hemşirelik Bölümü; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiIntroduction: The coronavirus disease 2019 (COVID-19) pandemic has significantly impacted various aspects of healthcare services, including emergency care services. Healthcare staff face mental issues and physical exertion when caring for patients potentially infected with COVID-19. Understanding the experiences and perspectives of emergency department (ED) healthcare staff during the COVID-19 pandemic is essential to inform evidence-based interventions and strategies to mitigate the impact on emergency care services. This study aims to investigate the experiences of ED healthcare staff regarding emergency care services during the COVID-19 pandemic, thus providing valuable insights into the challenges faced. Materials and methods: This study utilized a cross-sectional study design. Data were collected from 256 ED healthcare staff working in nine different hospitals located in Turkey between November 15, 2021, and December 30, 2021. Data were analyzed using descriptive statistics. Results: A total of 256 participants were included in the study. Of the participants, 58.6% were nurses, 19.5% were ED doctors, and 21.9% were emergency medical technicians. In addition, 67.2% of the participants were infected with COVID-19, and almost all of them (94.1%) were psychologically affected by the pandemic process. It was found that 85.2% of ED healthcare staff felt excluded by society due to being healthcare staff and 71.9% had to be separated from their families. Nurses were separated from their families at the highest rate (78%) during this period. Conclusion: More than half of the ED healthcare staff had problems accessing protective equipment and were separated from their families during the pandemic due to the risk of COVID-19 transmission. Although the number of ED visits decreased because of restrictions at the beginning of the pandemic, ED visits increased again with the abolition of restrictions.Article Citation - WoS: 1Citation - Scopus: 2Effect of Auricular Acupressure in Management of Constipation in Palliative Care Patients(Sage Journals Home, 2023) Bıçak Ayık, Derya; Can, Gülbeyaz; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiObjectives: This experimental randomized-controlled study was performed to define the efficacy of auricular acupressure (AA) in the management of constipation developing in palliative care patients. Methods: According to the pre-prepared randomization list, 44 patients were included in the experimental group and 46 patients were included in the control group. Routine clinical treatment and care implementation were maintained in the patients in both groups. AA was performed for 4 weeks in patients in the experimental group. During the study, to determine the complaints of the patients regarding constipation, the information in the daily patient chart was examined at least 5 times by interviewing with the patient/patient's relative in the clinic and/or via phone call, and the results were recorded in the patient chart and data collection forms. The independent variable of the study is AA application, and the dependent variables are constipation and quality of life. Results: It was determined that there was no statistically significant difference between the daily defecation frequency of the 2 groups during the first 11 days. However, after the 12th day, the daily stool frequency of the experimental group was higher compared to the control group and this difference obtained between the 2 groups was statistically significantly different. AA was effective in decreasing laxative use. Conclusion: This intervention increased stool frequency, reduced physical and psychosocial symptoms, anxieties, and improved stool satisfaction and it was an effective approach to improving the quality of life. It is recommended that the daily use of AA should be evaluated. The healthcare providers including nurses, patients, and patient relatives should be trained regarding AA.Article Citation - WoS: 27Citation - Scopus: 38The effect of ethnocentrism and moral sensitivity on intercultural sensitivity in nursing students, descriptive cross-sectional research study(Nurse Education Today, 2021) Yaşar, Beril Nisa; Kaya, Yunus; Arslan, Sevda; Erbaş, Atiye; Küçükkelepçe, Gürhan Erkuş; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiBackground: Factors affecting intercultural sensitivity and care are becoming an increasingly important issue due to ethnic diversity. Nurses play a crucial role in care and therefore should keep up with this trend and improve their intercultural sensitivity. Objective and design: This descriptive cross-sectional study investigated the effects of ethnocentrism and moral sensitivity on intercultural sensitivity in nursing students. Methods and participants: Data were collected using a demographic characteristics questionnaire and the Intercultural Sensitivity Scale, Generalized Ethnocentrism Scale, and Moral Sensitivity Scale. The sample consisted of 1343 nursing students. The Pearson correlation coefficient was used to determine correlations between scale scores. Multiple linear regression was used to determine the effects of ethnocentrism, moral sensitivity, and demographic characteristics on intercultural sensitivity. Results: Intercultural sensitivity was found to be negatively correlated with ethnocentrism and positively correlated with moral sensitivity. Ethnocentrism predicted intercultural sensitivity more than moral sensitivity. Ethnocentrism and moral sensitivity explained 16.8% of the total variance of intercultural sensitivity. However, ethnocentrism affected intercultural sensitivity more than moral sensitivity did (beta = −0.406). Conclusion: Nursing education should adopt strategies to reduce ethnocentrism by helping students develop cultural competence and intercultural sensitivity. Such education can equip nurses to provide higher quality care to patients of different cultural backgrounds.Article Citation - WoS: 5Citation - Scopus: 5Effect of Foot Massages on Postpartum Comfort and Pain Level of Mothers after Vaginal Delivery: A Randomized Trial(Holistic Nursing Practice, 2021) İçke, Sibel; Genç, Rabia; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiThis study conducted on 66 mothers aimed to investigate the effect of foot massages postpartum using an introductory information form, the Postpartum Comfort Scale, the visual analog scale, and a drug follow-up card. It was concluded that foot massages positively improved comfort, reduced pain levels, and reduced unnecessary medications.Article Citation - WoS: 2Citation - Scopus: 3The Effect of Skin-to-Skin Contact on Placental Separation Time and Initiation of Breastfeeding(Breastfeeding Medicine, 2023) Gündüz, Ülkin; Öztürk, Sibel; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiBackground: The first hour and minutes immediately after birth are quite important for both the mother and the newborn. Ensuring skin-to-skin contact (SSC) during this period has a positive effect on the mother both psychologically and physiologically, and it is also important in starting breastfeeding. Objective: The study was conducted to examine the effect of SSC on placental separation time and initiation of breastfeeding. Materials and Methods: This is a randomized controlled study. The sample of the study consists of a total of 84 women with primiparous birth and vaginal delivery, including 42 experimental and 42 controls. Data were collected using a personal information form, a chronometer, and the LATCH scale. The placental separation time for those in the experimental and control groups was determined by using a chronometer. Initiation and assessment of breastfeeding were evaluated at the first and 24th hours of birth using the LATCH scale. Results: The signs of placental separation occurred earlier in the experimental group than in the control group. The mean placental separation time was found to be 7.05 ± 4.37 minutes in the experimental group and 13.41 ± 5.24 minutes in the control group. A statistically significant difference was found between the groups in terms of placental separation time (p = 0.0001). Conclusion: This study concludes that SSC in the third stage of labor ensures earlier separation of the placenta and is effective in initiating breastfeeding.Article Citation - WoS: 16Citation - Scopus: 19Evaluation and characterization of Pleurotus eryngii extract-loaded chitosan nanoparticles as antimicrobial agents against some human pathogens(Taylor & Francis Online, 2020) Acay, Hilal; Yıldırım, Ayfer; Erdem Güzel, Elif; Baran, Mehmet Fırat; Baran, Mehmet Fırat; 09.03. Department of Nutrition and Dietetics/ Beslenme ve Diyetetik Bölümü; 21.02. Department of Medical Services and Techniques / Tıbbi Hizmetler ve Teknikleri Bölümü; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 21. Vocational School of Health Services / Sağlık Hizmetleri Meslek Yüksekokulu; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiWith the increase of antibiotic resistance, which is present at a worrying rate, research on the use of newly developed nanoparticles as an antimicrobial agent with green biotechnology has intensified. The study aimed to investigate the antimicrobial effects of chitosan nanoparticles (CSNP) synthesized using Pleurotus eryngii extract (PE). Characterization of P. eryngii-loaded chitosan nanoparticles (PE-CSNPs) was performed with Fourier transform infrared spectrophotometer, X-ray diffraction, Field-emission scanning electron microscopy, Brunauer-Emmett-Teller, Differential scanning calorimetry, and zeta potential techniques. The FE-SEM images showed that the surface morphology of nanoparticles is similar to CS, but has more porosity network and smaller dimensions structure. The average particle size of spherical PE-CSNPs was obtained as 330.1 nm. The specific surface area and average pore diameter of the synthesized nanoparticles were found as 3.99 m2g-1 and 2.25 nm, respectively. X-ray diffraction determines the presence of an amorphous peak at 2θ = 21.2° results from CS and PE. PE-CSNPs synthesized using P. eryngii extract showed strong antimicrobial activity against Escherichia coli, Staphylococcus aureus, Bacillus subtilis, and Candida albicans as 0.0156, 0.0625, 0.0625 and 0.0312 mg ml-1, respectively. Thus, it was determined that chitosan nanoparticles formed by the green synthesis of P. eryngii extract showed strong anti-microbial properties.Article Citation - WoS: 1Citation - Scopus: 1Evaluation of contraceptive intentions among pregnant women in the third trimester: A cross-sectional study(Wolters Kluwer, 2024) Yeşil, Yeşim; Dönmez, Ayşegül; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiThis study aims to determine contraceptive intentions of pregnant women in the third trimester. This cross-sectional study was conducted at a training and research hospital in Mardin province between March 2023 and May 2023. In total, 253 pregnant women who had the ability to communicate in Turkish and agreed to participate were included in the study. Data were collected through face-to-face interviews using a survey and the Contraceptive Intent Questionnaire (CIQ). The average age of the participants was 28.87 ± 5.35 with 30.8% of them holding a secondary school degree. It was found that there was a statistically significant difference in terms of CIQ score between categories of the following descriptive variables: education level, husband's/partner's education level, fertility plan, receiving family planning counseling during pregnancy, and paying for the contraceptive methods used (P = .046, P = .013, P < .001, P = .008, and P < .001 respectively). It was determined that pregnant women who had not received family planning counseling during pregnancy and paid for the contraceptive method had higher contraception intention.Article Evaluation of Nurses' and Midwives' Knowledge and Attitudes Towards Recognizing Violence Against Women(Womens Health & Action Research Centre, 2024) Yeşil, Yeşim; Yesil, Yesim; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiThe study was cross-sectional research that surveyed 410 nurses and midwives from March 2020 to March 2021 in Turkey. The aim of this study was to evaluate the knowledge and attitudes of nurses and midwives towards recognizing violence against women. The "Scale for Nurses' and Midwives' Recognition of the Symptoms of Violence against Women" were used. The average total scale score was 20.3 +/- 3.2. The score of participants who are receiving postgraduate education, working in the field of gynaecology and obstetrics, and considering intervention as a professional responsibility when encountering a woman who has experienced violence was found to be significantly higher than the other groups (p<.05). It is important for midwives and nurses to be aware of signs of violence to identify violence against women. Providing education to midwives and nurses regarding signs of violence against women will contribute to the recognition, prevention, and awareness of violence. (Afr J Reprod Health 2024; 28 [2]: 116-124)Article Evaluation of Prenatal Care Quality of Pregnant Women: a Cross-Sectional Sample From the South-East Turkiye(Womens Health & Action Research Centre, 2024) İçke, Sibel; Çifçi, Sema; Kocaturk, Asiye; 09.01. Department of Nursing / Hemşirelik Bölümü; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiThe aim of this study was to evaluate the quality of prenatal care among pregnant women in Mardin Artuklu. Study data were collected in August and September 2022. A total of 335 pregnant women participated in this descriptive research. The sociodemographic information form and Prenatal Care Quality Scale were used as data collection tools. The mean total score of the Prenatal Care Quality Questionnaire was 168.66 +/- 30.69. Results showed that prenatal visits more than 4 times, giving care from health centers, mothers educational level more than 12 years old, having health insurance are predisposing factors of quality of prenatal care (p<0.05). Although quality prenatal care is the right of every woman, there are still women who do not receive this care sufficiently and who are not aware of the care they receive. The role of midwives is important in raising awareness in women about the quality of prenatal care.Article Evaluation of Prenatal Comfort, Sleep, and Quality of Life in Pregnant Women With Cholestasis: a Cross-Sectional Study(Mdpi, 2024) Paşa, Semir; Gunduz, Ulkin; Yeşil, Yeşim; Pasa, Semir; 09.01. Department of Nursing / Hemşirelik Bölümü; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiBackground: Associated with adverse pregnancy outcomes, intrahepatic cholestasis of pregnancy is the most prevalent liver disease that women typically experience during pregnancy. This study aimed to evaluate prenatal comfort, sleep, and quality of life in pregnant women with cholestasis. Methods: This cross-sectional study was implemented between November 2022 and June 2023 at Mardin Training and Research Hospital with 150 pregnant women who received a diagnosis of pregnancy-induced intrahepatic cholestasis and agreed to participate. The following tools were utilized to collect data: A personal information form exploring socio-demographic and obstetric characteristics of participants, the Prenatal Comfort Scale (PCS), the Pittsburgh Sleep Quality Index (PSQI), and the World Health Organization Quality of Life-Brief Form (WHOQOL-BREF). Results: The mean age of participants was 27.79 +/- 6.33 years. The mean PCS and PSQI scores were 61.20 +/- 5.84 and 9.52 +/- 3.02, respectively. The mean scores of "physical health, psychological health, social relationships, and environmental health" sub-dimensions in WHOQOL-BREF were 10.63 +/- 2.18, 10.48 +/- 2.10, 11.31 +/- 3.28, and 11.27 +/- 2.10, respectively. A significant difference was found for PSQI regarding hospitalization status and change in sleep quality variables (p = 0.025 and p = 0.035, respectively). Conclusions: Cholestasis of pregnancy creates problems such as pruritus, body image changes, hospitalization, and poor sleep quality in women. This study showed that pregnant women with cholestasis had low levels of sleep quality and quality of life, implying that cholestasis affects their sleep quality, prenatal comfort levels, and quality of life in general. In addition, it is seen that women with this problem do not want to fall pregnant again.Article An Evaluation of the Syrian Pregnant Women's Prenatal Care Satisfaction: a Cross-Sectional Study(Univ Sao Paolo, 2025) İçke, Sibel; Çifçi, Sema; 09.01. Department of Nursing / Hemşirelik Bölümü; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiObjective: This study aims to examine the satisfaction levels of Syrian migrant pregnant women living in Mardin with prenatal care services and the factors influencing their satisfaction. Method: This is a cross-sectional study. The population of the study consisted of Syrian pregnant women who applied to Mardin Training and Research Hospital between August 15 and September 16, 2023. A total of 146 Syrian pregnant women who met the inclusion criteria participated in the study. The sociodemographic information form and the Prenatal Care Satisfaction Scale were used as data collection tools. Results: The rate of those who received prenatal care from a midwife/nurse is 80.1% and those who received less than 4 prenatal care was 89.7%. The most common reason for not receiving adequate prenatal care was lack of information with a rate of 39.7%. The mean score of the PCSS was 73.39 +/- 14.78. Conclusion: The study findings indicate that lack of information is one of the major barriers to healthcare access for migrant pregnant women. In addition, receiving prenatal care services from midwives/nurses affected satisfaction with prenatal care.Article Factors Affecting Maternal Satisfaction in Labor and Neonatal Outcomes: a Cross-Sectional Study(Womens Health & Action Research Centre, 2024) Yeşil, Yeşim; Yesil, Yesim; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiThis study evaluated the factors affecting maternal satisfaction during labor and neonatal outcomes. This cross-sectional study was conducted with 319 mothers who gave birth in ahospital (01.10.2023-31.03.2024) and volunteered for the study. Data were collected using a personal information form including socio-demographic and obstetric characteristics of the mothers and the 'Birth Satisfaction Scale'. The mean age of the mothers who participated in the study was 28.07 +/- 6.44 years. The mean score of the Birth Satisfaction Scale was 22.29 +/- 5.03. The sub-dimensions of the scale were found to be significantly affected by mode of delivery, various factors (p<0.05). Positive birth experience also affects maternal satisfaction. This study showed that maternal satisfaction in labor was at a moderate level. It explains that maternal satisfaction in labor is affected by the mode of delivery and other factors. In addition, it is seen that the method of delivery has various negative effects on the newborn.Article Citation - WoS: 1Citation - Scopus: 1Gynaecological Cancer Awareness and Healthy Lifestyle Behaviors of Women Aged 20-65 Years: a Descriptive Cross-Sectional Study(Womens Health & Action Research Centre, 2025) Yaşar, Beril Nisa; Seker, Sevda Arslan; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu ÜniversitesiFor both individual and community health, women's health is vital. In particular, gynecological cancers can be prevented or treated by adopting healthy lifestyles, raising awareness, and detecting them early. This study aimed to identify levels of gynecological cancer awareness and healthy lifestyle behaviors among women aged 20-65 years. There were 251 women in the descriptive cross-sectional study. The Gynecological Cancers Awareness Scale (GCAS), the Descriptive Characteristics Form, and the Healthy Lifestyle Behavior Scale-II (HLBS-II) were used to gather data. The data was analyzed using the Pearson's correlation test, multiple linear regression, and descriptive statistics. The average HLBS-II score was 123.53 +/- 20.75, while the average GCAS score was 149.64 +/- 21.30. The HLBS-II and GCAS scores showed a statistically significant positive correlation. Women knowledgeable about early diagnosis methods scored 10.758 times higher on the GCAS, while women familiar with vulvar self-examination scored 11.016 times higher. Employed women had a mean HLBS-II score 6.124 times higher than non-employed women (p<0.05). Women's awareness of gynecological cancer was high, but they also had moderately good lifestyle choices. To raise awareness and promote healthy lifestyle choices, healthcare professionals are advised to take part in health-promoting initiatives.