Browsing by Author "Kaya, A.F."

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Comparison of Chitosan-Containing Hemostatic Pad and Manual Compression After Coronary Angiography With Femoral Access
(Sociedade Brasileira de Cardiologia, 2024) Kiliç, R.; Güzel, T.; Aktan, A.; Kaya, A.F.; Department of Internal Medical Sciences / Dahili Tıp Bilimleri Bölümü; 10. Faculty of Medicine / Tıp Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Background: Femoral access remains a common choice in coronary angiography due to its easy accessibility and high success rate. Various techniques exist for achieving hemostasis following femoral artery catheterization. Objectives: The aim of our study is to compare the methods of chitosan-containing hemostatic pad (HP) and manual compression (MC) in terms of efficacy and safety in patients undergoing percutaneous coronary intervention (PCI) with coronary angiography via femoral access. Method: A total of 204 patients from 3 centers were included in our study between August 2021 and June 2023. The patients were divided into 2 groups, HP and MC, with 102 patients in each. Patients were evaluated for back and low back pain, complications, and duration of hemostasis immediately after angiography and up to 24 hours. Student’s t test and Mann-Whitney U test were used for numerical variables, while chi-square test was used for categorical variables. P < 0.05 was considered statistically significant. Results: Hemostasis time and back and low back pain were significantly lower in the HP group (7.5 ± 1.1 versus 15.1 ± 1.6, p < 0.001 and 2.13 ± 1.29 versus 4.22 ± 1.69, p < 0.001, respectively). While ecchymosis was found to be significantly lower in the HP group (2.9% versus 14.7%, p = 0.003), there was no significant difference in terms of other complications. Conclusion: HP was found to be more advantageous than MC in patients who underwent coronary angiography with femoral access. While ecchymosis and back and low back pain were found to be lower in the HP group, the absence of the need for sandbags also increases patient comfort. © 2024, Sociedade Brasileira de Cardiologia. All rights reserved.
Evaluation of the Relationship Between Uric Acid Level and Urıc Acide/Albumin Ratio with Stent Thrombosis in Patients Presenting Acute Coronary Syndrome
(Yuzuncu Yil Universitesi Tip Fakultesi, 2025) Kaya, A.F.; Aktan, A.; Sarikaya, R.
This study aimed to evaluate the relationship between uric acid level and urıc acide/albumin ratio (UAR) and stent thrombosis in patients with acute coronary syndrome (ACS). This single-center retrospective cohort study included 142 patients who underwent interventional treatment with stent implantation for ACS. The patients were divided into two groups: those who developed stent thrombosis within one year (n=67) and those who did not (n=75). Demographic, clinical, and laboratory data were collected from the hospital records. The uric acid/albumin ratio was calculated. Stent thrombosis is significantly associated with diabetes and hyperlipidemia.(respectively p=0,001, p=0,002) Uric acid levels were significantly higher and UAR was significantly lower in the stent thrombosis group. (respectively p= 0,001, p=0,001) The development of no reflow and post-dilatation was more frequent in the stent thrombosis group. ROC analysis revealed that a uric acid cut-off value of 5.55 had a sensitivity of 59.7% and a specificity of 64% for predicting stent thrombosis. The relationship between uric acid levels, UAR, and stent thrombosis likely involves complex processes including inflammation and oxidative stress. Understanding these relationships may contribute to the development of targeted interventions to reduce the risk of stent thrombosis and improve the outcomes of ACS patients undergoing stent implantation. © 2025 Elsevier B.V., All rights reserved.