Sağlık Bilimleri Fakültesi
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Article Citation - WoS: 18Citation - Scopus: 15Alpha-lipoic acid may ameliorate testicular damage by targeting dox-induced altered antioxidant parameters, mitofusin-2 and apoptotic gene expression(Andrologia, 2021) Güzel, Elif Erdem; Kaya Tektemur, Nalan; Tektemur, AhmetIn the study, the ameliorating effects of alfa lipoic acid (ALA) against doxorubicin-induced testicular apoptosis, oxidative stress and disrupted mitochondrial fusion were investigated in male rats. Rats were divided into four groups as control, doxorubicin (DOX), DOX + ALA and ALA. A single dose of 15 mg/kg DOX was administered i.p to the DOX and DOX + ALA groups. 50 mg/kg ALA was given to the DOX + ALA and ALA groups by oral gavage every other day. After 28 days, rat testes and serum samples were collected and analysed. Administration of DOX alone caused a decrease in body and relative testicular weights, seminiferous tubule diameter and germinal epithelium thickness, Johnsen's score and serum testosterone levels. DOX treatment led to severe testicular damage such as tubular degeneration, and atrophic tubules. Also, the activities of superoxide dismutase and glutathione peroxidase were reduced, while the level of malondialdehyde was increased in the testis. The mRNA levels of apoptotic-related genes (CASP3, TP53, BAX, BCL2) and apoptotic index were increased, while mitofusin-2 decreased. DOX caused an increase in CASP3 and a decrease in mitofusin-2 immunoreactivities. Treatment with ALA markedly improved all of DOX-induced biochemical, histochemical and molecular alterations in rat testis. Consequently, ALA has a therapeutic role in ameliorating DOX-induced testicular damage in rats.Article Citation - WoS: 10Citation - Scopus: 13The antioxidant and anti-apoptotic potential of Pleurotus eryngii extract and its chitosan-loaded nanoparticles against doxorubicin-induced testicular toxicity in male rats(Wiley, 2021) Erdem Güzel, Elif; Kaya Tektemur, Nalan; Tektemur, Ahmet; Acay, Hilal; Yıldırım, AyferThis study was conducted to evaluate the protective role of Pleurotus eryngii extract (PE) and Pleurotus eryngii extract-loaded chitosan nanoparticles (PE-CSNP) against doxorubicin (DOX)-induced testicular toxicity in rats. Male rats were divided into six groups: control (DMSO/ethanol), PE (200 mg/kg PE), PE-CSNP (30 mg/kg PECSNP), DOX (10 mg/kg DOX, a single dose, i.p), DOX+PE (10 mg/kg DOX+200 mg/ kg PE) and DOX+PE-CSNP (10 mg/kg DOX+30 mg/kg PE-CSNP). PE and PE-CSNP were administered by oral gavage every other day for 21 days. DOX-treated rats showed histopathological impairment compared with the control group. There was an increase in the apoptotic index, caspase 3 (CASP3), BCL2-associated X apoptosis regulator (BAX), dynamin-related protein 1 (DRP1) expression and total oxidative status (TOS) in the DOX group, while mitofusin-2 (MFN2), total antioxidative status (TAS) and serum testosterone levels of the DOX group reduced when compared with the other groups. PE and PE-CSNP treatments provided significant protection against DOX-induced oxidative stress by reducing TOS levels and increasing TAS levels. CASP3, BAX, apoptotic index and DRP1-MFN2 expressions were restored by PE and PE-CSNP. However, the PE-CSNP showed higher antioxidant and anti-apoptotic efficacy compared with PE. Thus, our results provide evidence that CSNP and PE could synergistically have a potent antioxidant and anti-apoptotic therapy against DOX-induced testicular damage in male rats.Article Citation - WoS: 7Citation - Scopus: 7Biochemical components, enzyme inhibitory, antioxidant and antimicrobial activities in endemic plant Scilla mesopotamica speta(Wiley, 2021) Aktepe, Necmettin; Keskin, Cumali; Baran, Ayşe; Atalar, Mehmet Nuri; Baran, Mehmet Fırat; Akmeşe, ŞükrüIn this study, in vitro antioxidant, antimicrobial, anticholinesterase and phenolic profile of different solvent extracts of Scilla mesopotamica speta were determined in detail. In vitro antioxidant activities and total phenolic and flavonoid contents of plant extracts obtained with different solvents were tested in terms of 2.2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activities. The highest total phenolic and total flavonoid contents were determined in the ethyl acetate extract (62.24 mu g GAE/mg) and chloroform extract (87.72 mu g QE/mg) respectively. The highest DPPH radical scavenging activity was detected in ethyl acetate extracts. Antimicrobial and antifungal activities were investigated by MIC method. The inhibitory activities of the extracts on the acetyl cholinesterase enzyme were investigated. Liquid chromatography (LC) tandem mass spectrometry LC-MS/MS was used to determine the phenolic component content of extracts. Thirty-one different components were identified in the analyses and their amounts were measured. Practical applications Scilla mesopotamica speta is an endemic and medicinal plant. It was determined that the extracts of this plant had a very rich content in terms of phenolic compounds, especially caffeic and ferulic acids. However, this plant was remarkable for its antioxidant, anticholinesterase, and antimicrobial activities. Considering the strong antioxidant, antimicrobial, and enzyme inhibition activities of the Scilla mesopotamica speta it can be suggested as a source of anticancer, antimicrobial, and antiviral drugs.Article Citation - WoS: 62Citation - Scopus: 70Changes in volatile compounds, sugars and organic acids of different spices of peppers (Capsicum annuum L.) during storage(FOOD CHEMISTRY, 2020) Korkmaz, Aziz; Atasoy, Ahmet Ferit; Hayaloglu, Ali AdnanChanges in sugars, organic acids and volatile compounds (VC) of red pepper flakes (RPF), traditional (TRI), and industrial (INI) isot peppers were evaluated during one year storage at the room condition. The changes in the flavor components were significantly affected by the production methods and storage time. Glucose content decreased gradually along storage and reduced by about 21.23, 47.22 and 56.65% for TRI, INI and RPF, respectively. However, fructose decreased significantly only in RPF (11.29%). Citric and succinic acids exhibited slight changes, but malic acid showed an increasing trend, especially in RPF (4-fold). Most of the VC in all samples decreased or disappeared after storage. The major quantitative losses in these compounds were found in TRI during the first 3 months as 81.76%. The storage was found to be caused deterioration flavor properties in red pepper spices and revealed the importance of appropriate storage conditions.Article Citation - WoS: 25Citation - Scopus: 24Characterization and Comparison of Extra Virgin Olive Oils of Turkish Olive Cultivars(Molecules, 2023) Korkmaz, AzizExtra virgin olive oils (EVOOs) obtained from five Turkish olive cultivars widely produced in the Aegean and Marmara regions were investigated based on their total antioxidant capacity (TAC), total phenolic content (TPC), pigment contents, fatty acid (FA) profiles, phenolic compounds (PC), volatile compounds (VC), and sensory properties. The results showed that all properties of EVOO samples were significantly affected by the olive cultivar used. The pigment contents in Ayvalık (9.90 mg·kg−1) and Uslu (9.00 mg·kg−1) oils were higher than the others (p < 0.05). The greatest values for oleic acid (74.13%) and TPC (350.6 mg·kg−1) were observed in Gemlik and Domat oils, respectively (p < 0.05). Edincik oil showed the maximum hydroxytyrosol content (48.022 mg·kg−1) and TAC value (515.36 mg TE·kg−1) (p < 0.05). The Edincik, Domat, and Uslu oils were significantly not different for the total content of C6 compounds derived by lipoxygenase, which are the main volatiles responsible for the typical aroma of EVOOs (p > 0.05). Domat oil also exhibited the highest scores for bitterness and pungency perceptions (p < 0.05). The fruitiness scores of the oil samples (except for Ayvalık oil) were close to each other, even if they were statistically different (p < 0.05). Principal component analysis (PCA) indicated that the Ayvalık oil was separated from the others due to its poor-quality characteristics. As a result, it can be stated that Domat olive oil has better quality than the othersConference Object Correlation between vitamin D status and Wechsler Adult Intelligence Scale's comprehension subtest in patient with end-stage renal diseases(WILEY-BLACKWELL, 2016) Karaoğlan, Mehmet; Emre, Memet Hanifi; Demirtaş, Yasemin; Şahin, İdris; Taşkapan, HülyaAim: Cognitive decline is an important problem for individuals, as well as for the community. Increasing evidence suggests that vitamin D may play a role in maintaining cognitive function and vitamin D deficiency may accelerate cognitive decline. The aim of this study was to evaluate the status of vitamin D in chronic renal failure (CRF) patients on peritoneal dialysis (PD) and to correlate the findings with cognitive functions. Materials and methods: The study was performed in Inonu University Turgut Ozal Medical Center. Serum 25hydroxyvitamin D (25(OH)D) was measured and cognitive functions (Wechsler Adult Intelligence Scale’s (WAIS) Comprehension Subtest) tested with 51 peritoneal dialysis patients and a control group consisting of 51 healthy individuals have similar conditions with patients. Individuals with other chronic diseases and smoking and alcohol habits which may impair cognitive functions were excluded from the study. Results: Compared to each groups we found negative correlation between 25(OH)D3 levels and WAIS’s Comprehension Subtest in patient and control group. The correlation between data was evaluated with the Spearman’s test (P = 0.597, r = 0.76 and P = 0.010 r = 0.356 respectively). Conclusions: In the literature, there is no consensus on the presence of an association between vitamin D levels and cognition. In this study vitamin D levels were measured as deficiency in both groups. Further studies are needed to investigate for increasing actual knowledge about this association.Article Citation - WoS: 43Citation - Scopus: 48Corrosion behavior of mild steel in 1 M HCl with Cyclotrichium niveum as a green inhibitor(Elsevier, 2024) Yıldız, Reşit; Arslanhan, Selim; Döner, Ali; Baran, Mehmet FıratRecently, green inhibitors are replacing classical inhibitors in the acid cleaning industry due to very low cost, environmentally friendly and none toxic. In this study, Cyclotrichium niveum is used as a potential green corrosion inhibitor to investigate the corrosion behavior of mild steel (MS) in chloride solution using electrochemical, morphological, structural and quantum chemical methods. Fifty-three flavonoids are detected in methanol extract of cyclotrichium niveum by LC/ESI-MS/MS. While icorr values decreased, Rp and inhibition efficiencies values derived from electrochemical impedance spectroscopy (EIS) and linear polarization resistance (LPR) increased in increasing inhibitor concentrations. Maximum inhibition efficiency is found to be 97.3%, that is the almost highest value, when compared to previous studies and plant extract is classified as a mixed type inhibitor with respect to the potentiodynamic polarization (PDP). The model that best fits the experimental values is the Langmuir isotherm. The temperature effect is also studied in the range of 25–55 ○C. Higher activation energy is obtained in the presence of inhibitor, suggesting that it acts as an efficient inhibitor by forming a physical barrier to the charge and mass transfer reaction, leading to reduction in corrosion rate. Scanning electron and atomic force microscopies showed the more uniform, crack and pits free structure, confirming that there is a protective film over the MS surface for inhibited solution. XPS analysis showed the existence of C, O, and Fe atoms on the MS surface. Quantum chemical calculation manifested the adsorption mechanism associated with the electronic structure of the molecules. The findings of this work can be applicable in chemical cleaning process with acid treatment.Article Citation - WoS: 3Citation - Scopus: 3Discrimination Based on Sexual Orientation “Homophobia in Healthcare Employees”: a Cross-Sectional Study(Springer, 2025) Deger, Vasfiye Bayram; Kacan, HavvaIntroductionThe study was conducted to examine the attitudes of healthcare employees toward homosexuals and the factors affecting them, while homophobic thoughts and behaviors are based on heteronormative cultural beliefs and gender stereotypes.MethodsThis study was planned as a cross-sectional and completed with 720 healthcare employees. The Demographic Information Form and Hudson and Ricketts Homophobia Scale were used in the study. Data were collected between January 06 and January 10, 2022.ResultsThe mean homophobia total score of the employees was determined as 97,503 +/- 25,807. Homophobia levels of male healthcare employees, those who thought homosexuality is a disease, and those who stated that homosexuality can be caused by taking an example had increasing homophobia levels. The level of homophobia decreases in the presence of homosexual friends, those who can talk freely about homosexuality, and healthcare employees who support same-sex marriage.ConclusionsRecognition of individuals with different sexual orientations by healthcare employees will reduce homophobic attitudes toward these individuals. Examining the level of homophobia in healthcare institutions and ensuring that discriminatory attitudes or behaviors toward individuals from different sexual orientations are determined to be effective on the quality of healthcare and access to healthcare services.Policy ImplicationsThere is a healthcare system in which patients are generally assumed to be heterosexual; healthcare employees are not prepared to work with Lesbian, Gay, Bisexual, and Transsexual patients in general. Studies conducted on this subject indicate that more studies are needed on the subject to implement a healthcare policy focusing on sexual diversity in healthcare services and to discuss healthcare practices for the Lesbian, Gay, Bisexual, and Transsexual population.Editorial Citation - WoS: 4Citation - Scopus: 4Editorial: Anxiety, burnout, and stress among healthcare professionals(Frontiers, 2023) Bayram Değer, VasfiyeThe technology, informatics and social fields are experiencing continuous changes and developments day by day. Such changes and developments influence human life and expand the fields of research. One of these fields is the world of work life. Work life is an area where people spend a significant part of their lives by spending time and effort. The willingness of employees to make quality use of their time and labor significantly affects the efficiency obtained as a result of their work (Burton, 2010). The nature of the work requirements and the quantity of communication with other people in the workplace create challenging situations for employees. In this context, when it comes to health in work life, health workers are seen as an important sample group in terms of researching variables in work life, since their field requires qualified labor force, is vital and is a profession that constantly involves face-to-face interaction with people. The health sector is one of the sectors where employees have the most difficulties due to various factors. The health sector differs from other working environments due to the difficulty of serving patients with severe stress and the fact that employees in this sector often face stressful situations in their daily working environment.Article The effect of acupressure on postoperative pain of lumbar disc hernia: A quasi-experimental study(ELSEVIER, 2018) Tanrıverdi, Seher; Sarıtaş, SerdarThe effect of acupressure on postoperative pain of lumbar disc hernia Background: This study has been conducted for the purpose of examining the effect of acupressure on postoperatıve paın of lumbar disc hernia. Methods: This research was conducted between January 2015- July 2016 at the Neurosurgery Clinics of Turgut Özal İnönü University and Malatya State Hospital as a quasi-experimental research with pretest-posttest designs. The study population consisted of patients who were hospitalized in these clinics after operation of lumbar disc hernia. The sample group consisted of 112 patients selected with random sampling and stayed in these clinics after the power analysis (56 test, 56 control). This research data was collected between January 2016 - March 2016. Patient identification forms and visual analog scales (VAS) were used for data collection. Patient identification form was applied to the patients in the experimental group, after acupressure was applied to patients for 15-20 minutes, their level was determined with the VAS. When the acupressure was stopped, their pain was determined with the VAS. Whereas in the control group, their pain was determined with the VAS and taking the end of the time during which acupressure was applied to experimental group into consideration, their pain level was reevaluated in the 20th minute. Data were evaluated with percentage, arithmetic average, chi-square test and independent groups t test. Results: The research result showed that owing to the effect of acupressure the pain level of the experimental group decreased from 7.75±1.67 to 2.58±1.18. (p= .00). Conclusions: Hence this result suggests the effectiveness of acupressure on postoperatıve paın of lumbar disc hernia.Article Citation - WoS: 5Citation - Scopus: 7The effect of acupressure on postoperative pain of lumbar disc hernia: A quasi-experimental study(ELSEVIER SCI LTD, 2018) Tanrıverdi, Seher; Sarıtaş, SerdarLumbar disc herniation (LDH) is a disease characterized by lumbar and leg pain that occurs as a result of compression of the lumbar spinal root by the degenerated disc. The results of the study showed that 80% of humans experienced lumbar pain in any period of their lives [[1], [2], [3]]. Comprising an important part of lumbar pain; lumbar disc herniation (LDH) has an prevalence of approximately 15–56% per year [4,5]. One of the treatment methods preferred for patients diagnosed with lumbar disc herniation is surgery. Patients, who undergo surgery, experience intense pain in the early postoperative period [6]. It is known that medications are commonly used in pain control. Analgesic treatment used for pain control is the most preferred treatment method for pain relief as it has a rapid action and is administered easily [7,8]. Damages in both individual and national economy due to preferring carelessly and frequently analgesics affect negatively some physiological functionings and have negative effects such as development of addiction with the increase of dosages every time especially in cases where narcotics are preferred [9]. Thus, it is indicated that the administration of non-pharmaceutical methods by nurses to relieve the postoperative pain in patients in addition to medications increases the action of medications [8]. It is anticipated that there are numerous non-pharmaceutical methods which are efficient in pain management, such as distraction, relaxation, therapeutic touch, transcutaneous nerve stimulation (TENS), informing, hypnotherapy, acupuncture, massage, aromatherapy, music and meditation, yoga, attention-grabbing, imagination, cognitive-behavioral techniques. But, it is known that nurses do not use these methods adequately to relieve pain [10]. It may be asserted that non-pharmaceutical treatments are among independent nursing roles of professional nurses who have theoretical knowledge and problem solving ability. Nurses are required to take a role in non-pharmaceutical interventions in order to meet the health needs of individuals, families and society [11]. One of the non-pharmaceutical treatment methods used in pain relief is acupressure. Applied with touch pressuring on the acupuncture points using hands, fingers, thumbs or small beads according to the traditional Chinese medicine; acupressure is a non-pharmaceutical pain relief example that balances energy in the body [[12], [13], [14]]. Advantages of acupressure include low cost, learning convenience and non-invasive characteristics [14]. Besides, randomized clinical studies conducted to compare physiotherapy and acupressure in decreasing lumbar pain (LBP) have reveal that acupressure might be effective [[15], [16], [17]]. The use of acupressure in nursing practices by taking all its positive effects into consideration will contribute to the establishment of qualified nursing care standards.Conference Object Effect of Agro-Industrial Wastes on Production of Laccase in Submerged Cultures of Some Wild Mushrooms(Elsevier Science Bv, 2012) Acay, Hilal; Keskin, Cumali; Kacar, SemraArticle Citation - WoS: 1Citation - Scopus: 2Effect of Auricular Acupressure in Management of Constipation in Palliative Care Patients(Sage Journals Home, 2023) Bıçak Ayık, Derya; Can, GülbeyazObjectives: This experimental randomized-controlled study was performed to define the efficacy of auricular acupressure (AA) in the management of constipation developing in palliative care patients. Methods: According to the pre-prepared randomization list, 44 patients were included in the experimental group and 46 patients were included in the control group. Routine clinical treatment and care implementation were maintained in the patients in both groups. AA was performed for 4 weeks in patients in the experimental group. During the study, to determine the complaints of the patients regarding constipation, the information in the daily patient chart was examined at least 5 times by interviewing with the patient/patient's relative in the clinic and/or via phone call, and the results were recorded in the patient chart and data collection forms. The independent variable of the study is AA application, and the dependent variables are constipation and quality of life. Results: It was determined that there was no statistically significant difference between the daily defecation frequency of the 2 groups during the first 11 days. However, after the 12th day, the daily stool frequency of the experimental group was higher compared to the control group and this difference obtained between the 2 groups was statistically significantly different. AA was effective in decreasing laxative use. Conclusion: This intervention increased stool frequency, reduced physical and psychosocial symptoms, anxieties, and improved stool satisfaction and it was an effective approach to improving the quality of life. It is recommended that the daily use of AA should be evaluated. The healthcare providers including nurses, patients, and patient relatives should be trained regarding AA.Article Citation - Scopus: 7The Effect of Progressive Muscle Relaxation on Abdominal Pain and Distension in Colonoscopy Patients(ELSEVIER, 2023)Purpose:This study was conducted to examine the effect of progressive muscle relaxation on abdominal pain and distension in colonoscopy patients. Design:A randomized controlled experimental design. Methods:The experimental group was informed about progressive muscle relaxation(PMR) and anaudio recording was provided. After the colonoscopy,abdominal pain(VisualAnalogueScale(VAS)pain) and distension (VAS distension) scores were assessed, then PMR was applied for 30 minutes and pain scores were determined again.VAS pain and VAS distension scores of the control group were determined after colonoscopy and 30 minutes later.VAS abdominal pain and VAS distension scores were evaluated at the 2nd,4th, 8th,12th,16th,and 24th hour after the procedure on all patients.The day after thec olonoscopy, post-test data were collected. Findings:The pretest VAS pain and VAS distension mean scores were similar in thei ntervention and control groups(P>.05). The mean VAS pain and VAS distension scores decreased significantly in thei ntervention group post procedure(P<.05). Conclusions:PMR was determined to be effective in reducing abdominal pain and distension after colonoscopy.Article Citation - WoS: 6Citation - Scopus: 7The Effect of Progressive Muscle Relaxation on Abdominal Pain and Distension in Colonoscopy Patients(ScienceDirect, 2022) Tanrıverdi, Seher; Parlar Kılıc, SerapAbstract Purpose This study was conducted to examine the effect of progressive muscle relaxation on abdominal pain and distension in colonoscopy patients. Design A randomized controlled experimental design. Methods The experimental group was informed about progressive muscle relaxation (PMR) and an audio recording was provided. After the colonoscopy, abdominal pain (Visual Analogue Scale (VAS) pain) and distension (VAS distension) scores were assessed, then PMR was applied for 30 minutes and pain scores were determined again. VAS pain and VAS distension scores of the control group were determined after colonoscopy and 30 minutes later. VAS abdominal pain and VAS distension scores were evaluated at the 2nd, 4th, 8th, 12th, 16th, and 24th hour after the procedure on all patients. The day after the colonoscopy, post-test data were collected. Findings The pretest VAS pain and VAS distension mean scores were similar in the intervention and control groups (P > .05). The mean VAS pain and VAS distension scores decreased significantly in the intervention group post procedure (P < .05). Conclusions PMR was determined to be effective in reducing abdominal pain and distension after colonoscopy.Article Citation - WoS: 23Citation - Scopus: 30Effect of seasonal variation on lipid and fatty acid profile in muscle tissue of male and female Silurus triostegus(SPRINGER INDIA, 2016) Kacar, Semra; Bashan, Mehmet; Oymak, Seyit AhmetFatty acid (FA) compositions of total lipid, phospholipid (PL) and triacylglycerol (TAG) fractions have been determined in muscle tissues of Silurus triostegus. The distributions of saturated fatty acid (SFA), monounsaturated fatty acid (MUFA) and polyunsaturated fatty acid (PUFA) proportions were found to be different among total lipid, PL and TAG fractions from lipids in muscle tissues of the male and female S. triostegus in all seasons. Triacylglycerol contained a lower proportion of PUFA and a higher proportion of MUFA and SFA than PL while PL contained higher proportion of PUFA than proportion of MUFA and SFA compared to TAG. Triacylglycerol and PL fatty acid compositions in muscle tissues of the male and female fish species were found different. The most abundant fatty acids in the investigated seasons were palmitic acid (C16:0), stearic acid (C18:0), oleic acid (C18:1 n-9), palmitoleic acid (C16:1 n-7) and docosahexaenoic acid (C22:6 n-3). It was shown that the total lipid content and FA compositions in muscle tissues of the male and female S. triostegus were influenced by reproduction period and season.Article Citation - WoS: 16Citation - Scopus: 16Effect of therapeutic touch on daytime sleepiness, stress and fatigue among students of nursing and midwifery: A randomized sham-controlled trial(Complementary Therapies in Clinical Practice, 2021) Utli, Hediye; Vural Doğru, Birgül; Şenuzun Aykar, FisunObjectives: This study was conducted to assess the effect of therapeutic touch on stress, daytime sleepiness, sleep quality and fatigue among students of nursing and midwifery. Methods: 96 students were randomized into three groups: the therapeutic touch (TT) group, the sham therapeutic touch (STT) group, and the control group. In this randomized sham-controlled study, the TT group was subjected to therapeutic touch twice a week for four weeks with each session lasting 20 min. Results: When the TT group was compared to the STT and control groups following the intervention, the decrease in the levels of stress (p < 0.001), fatigue (p < 0.001) and daytime sleepiness (p < 0.001), and the increase in the sleep quality (p < 0.001) were found to be significant. Conclusion: It was found that TT, which is one form of complementary therapy, was relatively effective in decreasing the levels of stress, fatigue and daytime sleepiness, and in increasing the sleep quality of university students of nursing and midwifery.Article Citation - WoS: 4Citation - Scopus: 5The Effect of Virtual Rainforest and a White Noise Mobile Application on Satisfaction, Tolerance, Comfort, and Vital Signs During Arthroscopy(Elsevier Sci Ltd, 2024) Genc, Hasan; Tanriverdi, Seher; Akar, Mehmet SaitBackground and purpose: This study was conducted to investigate the effect of Virtual Rainforest (VRF) and a White Noise (WN) mobile applications on patient satisfaction, tolerance, comfort, and vital signs during arthroscopic knee surgery. Methods: This is a randomized, controlled, interventional study. The study was completed with a total of 93 participants, 31 in the VRF group, 31 in the WN group, and 31 in the control group. Data were collected using a Patient Information Form and a Visual Analog Scale for satisfaction, tolerance, and comfort. Results: The results of study showed that there were significant increases in tolerance, satisfaction, comfort, respiratory rate, and oxygen saturation levels and significant decreases in heart rate, systolic and diastolic blood pressures in both VRF and WN groups (p < .05). In the control group, no significant difference was found between the means of the variables before and after the procedure (p > .05). Conclusion: According to the results of the study, VRF and WN applied during the arthroscopy procedure increased satisfaction, tolerance, and comfort in patients and had a positive effect on vital signs. Trial and protocol registration: ClinicalTrials.gov, NCT05992714.Article Citation - WoS: 1Citation - Scopus: 2Effects of clinical practicum on nursing students' self-efficacy: Example of internal medicine wards(Wiley, 2021) Kankaya, Hülya; Keskin, Hülya; Akyol, AsiyePurpose: To evaluate the effects of clinical practicum on nursing students' self-efficacy (perceptions of confidence and importance) in internal medicine wards and the factors affecting it. Design and Methods: The single group pre-post descriptive study was conducted with 134 final-year nursing students practicing in internal medicine wards. Findings: At the beginning of the practicum, the mean score of confidence and importance subscales were 3.72 ± 0.77 and 4.25 ± 0.57, respectively. At the end of the practicum, the mean score of confidence and importance subscales were 3.91 ± 0.70 and 4.81 ± 0.76, respectively. We found that there was a significant improvement in both subscales at the end of the practicum (p < 0.05). Practice Implications: Clinical practicum positively affects students' self-efficacy in internal medicine wardsArticle Citation - WoS: 2Citation - Scopus: 2Electrochemical Behavior of Pt Nano-Particles Dispersed on Cu/Ni Electrode in Alkaline Environment(Pergamon Elsevier Science Ltd, 2024) Doslu, Serap Toprak; Doner, AliThe development of a low-cost Pt-based electrocatalyst for industrial water splitting is important. In this study, to prepare cost-efficient Pt-based electrocatalyst for hydrogen evolution, Cu electrode is deposited with nickel (Cu/ Ni) and this surface is modified with Pt nanoparticles by electrodeposition method (Cu/Ni-Pt). The surface properties of the produced electrocatalysts are studied via X-ray diffraction (XRD), scanning electron spectroscopy (SEM), energy dispersive X-ray analysis (EDX), transmission electron microscopy (TEM) and atomic force microscopy (AFM). Characterizations demonstrated that the coating is homogeneous and compact. Hydrogen evolution and corrosion behaviors of prepared electrode (Cu/Ni-Pt) are examined in 1.0 M KOH solution using cyclic voltammetry (CV) and cathodic and anodic current-potential curves, electrochemical impedance spectroscopy (EIS). Tafel slope is determined to be 133 mV dec(-1) on Cu/Ni-Pt. Very high exchange current density (5.65 mA cm(-2)) and very low charge transfer resistance (0.91 Omega cm(2) at 1.05 V vs RHE) are measured again on this electrocatalyst. High activity is due to intrinsic activity of Pt and synergistic interaction of Pt and Ni. Besides, Cu/Ni-Pt exhibits so stable structure over 4 h without any current densities decay as well as showing good corrosion performance after long-term immersion times and these properties make it possible electrocatalyst with high corrosion resistant and activity in the water electrolysis systems.
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