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Citation - WoS: 6
Citation - Scopus: 9
Adaptions in subsistence strategy to environment changes across the Younger Dryas-Early Holocene boundary at Kortiktepe, Southeastern Turkey
(Sage Journals, 2022) Emra, Stephanie; Benz, Marion; Sıddıq, Abu Bakar; Özkaya, Vecihi
The site of Körtiktepe in southeastern Turkey is one of few sites in the Upper Mesopotamia basin that attests continuous, permanent occupation across the boundary from end of the colder, drier Younger Dryas (YD) into the comparatively wetter and warmer Early Holocene (EH). This allows for the study of the degree of environmental change experienced on a local level over this boundary as well as for the study of the adaptations that the occupants of the site undertook in response to these changes. The mammal assemblage of Körtiktepe remains relatively stable across the YD – EH transition with the main contributors to diet being mouflon (Ovis orientalis) and red deer (Cervus elaphus) in approximately the same quantities, although the contribution of aurochs (Bos primigenius) increases in the EH. The most significant changes can be seen in the shift in avifauna remains, with a sharp increase of waterbirds during the EH. It is proposed that these shifts reflect changes in the local environment with an increase in woodland cover as well as expansion of local waterways, which is generally consistent with previously published archaeobotanical studies. In terms of species exploited, mortality profiles as well as size distribution of mammals, a great deal of continuity is observed. This suggests that over this particular period the local impact of the beginning of the Early Holocene was not overly dramatic, allowing for cultural continuity of previously established subsistence strategies.
Citation - WoS: 22
Citation - Scopus: 22
Aflatoxin M1 in Human Breast Milk in Southeastern Turkey
(Springer Heidelberg, 2017) Altun, Serap Kilic; Gurbuz, Semra; Ayag, Emin
This study was performed to determine aflatoxin M-1 (AFM(1)) in human breast milk samples collected in AanlA +/- urfa, located in Southeastern region of Turkey, and to investigate a possible correlation between AFM(1) occurrence (frequency and levels) and sampling seasons. Human breast milk samples collected in December 2014 and in June 2015 from a total of 74 nursing women, both outpatient and inpatient volunteers in hospitals located in AanlA +/- urfa, Turkey, were analyzed using competitive enzyme-linked immunosorbent assay (ELISA) for the presence of AFM(1). AFM(1) was detected in 66 (89.2%) out of 74 samples at an average concentration of 19.0 +/- 13.0 ng/l (min.-max., 9.6-80 ng/l). There was a statistically significant difference between December and June concerning AFM(1) levels (p < 0.05). Further detailed studies will be needed to determine the main sources of aflatoxins in food, to establish protection strategies against maternal and infant exposure to these mycotoxins.
Alman Oryantalizmi ve İslami Dönem Fars Edebiyatı: Bir Literal Geçişkenlik Örneği Olarak Josef von Hammer-Purgstall (1774–1856)
(2019) Avcı, Remzi
Avrupa‘da İslami dönem Fars dili, kültür ve edebiyatına duyulan ilginin tarihi oldukça eski bir geleneğe dayanmaktadır. Çeviri hareketleri bağlamında düşünüldüğünde İslami dönem Fars edebiyatının Avrupa ile metinsel temasının 17. yüzyılda başladığı söylenebilir. Coğrafya ve kültüre duyulan yakın ilgi seyyahların dil ve edebiyata ilgisini de beraberinde getirmiştir. Bu dönemde birçok Alman seyyah Safevi ülkesine seyahat etmiş ve tarih, kültür, dil ve İslami dönem Fars edebiyat üzerine geniş bilgiler toplayarak bunları Batı’ya aktarmıştır. 1634 yılında Fars edebiyatı klasiklerinden olan Şeyh Sa‘dî-i Şîrâzî’nin Gülistan adlı eseri Fransız oryantalist André du Ryer (1580-1660) tarafından Fransızcaya çevrilmiştir. Friedrich Ochsenbach (1606–1658), söz konusu çeviriyi 1636 yılında Fransızcadan Gulistan, das ist, Königlicher Rosengarten/Gülistan, Kraliyet Gül Bahçesi başlığı ile Almancaya çevirmiştir. Safevi ülkesinde medreselerde Farsça öğrenerek Sa‘dî’nin eserleri ile tanışmış olan Adam Olearius/Ölschläger (1600–1671), Almanya’ya döndükten sonra Safevi elçisinin yardımıyla Gülistan’ı 1654 yılında Persianische Rosenthal/Fars Güller Vadisi adıyla Almancaya çevirmiştir. 18. yüzyılın sonlarına doğru Avrupa’da Hâfız-ı Şîrâzî ve Şeyh Sa‘dî-i Şîrâzî gibi İslami dönem Fars şairlerinden Batı dillerine yapılan edebi metin çevirilerdeki artış oryantalistlerden şairlere kadar Almanca konuşulan dünyada da etkisini göstermiştir. Bu zaman dilimi Doğu ve Batı arasında ilişkide bir dönüm noktası olarak düşünülebilir. 19. yüzyılın ise ilk yıllarında diplomat, seyyah, tüccar ve oryantalistlerin yaptıkları çeviriler ile başlayan ve gelişen edebî oryantalizm Almanca konuşulan dünyada Doğu’dan Batı’ya bir Fars şiiri çeviri külliyatı bırakmıştır. Söz konusu külliyatın oluşumunda oldukça önemli bir yerde duran Avusturyalı oryantalist Josef von Hammer-Purgstall (1774-1856), Vinzenz Rosenzweig von Schwannau (1791-1865), Valentin von Huszár (1788-1850), Johann Wolfgang von Goethe (1749-1832), Friedrich Rückert (1788-1866) ve August von Platen (1796-1835) gibi aydınlanmacı, klasik ve romantik akımdan ve birçok düşünür şair ve oryantalistin Fars dili ve şiirine ilgi duymalarında önemli bir etki bırakmıştır. Hammer-Purgstall’ın İslami dönem Fars şiiri çevirilerinden literal bir ağ yarattığınıiddia eden bu çalışma, onun çevirilerinin Alman edebi oryantalizminin inşa ve kurumsallaşmasında nasıl bir rol oynadığını incelemektedir
Citation - WoS: 8
Citation - Scopus: 8
Analysis of bioactive compounds using LC-ESI-MS/MS, cytotoxic, antimicrobial effects, and enzyme activities from Cyclotrichium origanifolium
(Wiley Online Library, 2022) Aktepe, Necmettin; Baran, Ayşe; Atalar, Mehmet Nuri; Baran, Mehmet Fırat; Keskin, Cumali; Taşkin, Abdullah; Yavuz, Ömer; Demirtaş, İbrahim; Oğuz, Ercan; Jahan, Israt
Cyclotrichium origanifolium is a medicinal plant belonging to the Lamiaceae family. In this study, phenolic content analysis, antimicrobial effects, and cytotoxic effects of extracts of C. origanifolium were investigated. In the extracts, phenolic compound analysis by the liquid chromatography–electrospray ionization– tandem mass spectrometry method, antimicrobial effect by the minimum inhibition concentration method, and cytotoxic effect on human dermal fibroblasts (HDF), glioblastoma cell (U87), ovarian adenocarcinoma cell (Skov-3), and human colorectal adenocarcinoma cell (CaCo-2) cancer cell lines were investigated. Cytotoxicity analyses were performed by the MTT method. In addition, the GST and AChE enzyme activities of the extracts were also measured. Around 18 compounds were detected in both the methanol and ethanol extract. It was found that the best antimicrobial effect on Gram-negative Pseudomonas aeruginosa was on methanol extract, while the ethanol extract was on Candida albicans fungus (respectively, 2.50mg/ml, 5.0 μg/ml). A 500μg/ml of methanol extract has been shown to have cytotoxic activity high effect on HDF cells. GST and AChE activity were found to decrease in a concentration-dependent manner.
Animal remains of Alaybeyi Höyük
(Turkish Journal of Veterinary and Animal Sciences, 2019) Sıddıq, Abu Bakar
This paper presents the zooarchaeological observations on animal remains of Alaybeyi Höyük unearthed from 2016 and 2017 excavation sessions. Dated to 4721–4553 cal. BC, Alaybeyi stands so far as the oldest archaeological settlement discovered in northeast Anatolia. Therefore, the faunal assemblage at Alaybeyi offers great opportunity to study the status of animals and their relationships with humans in the largely unexplored Kars-Erzurum plateau covering a period from the Chalcolithic to Late Iron Age. Taxonomic and osteometric analyses show that, like the present day, cattle were dominant over caprines, revealing extensive cattle pastoralism in the region for at least about 7 millennia. While caprines too were significant in the subsistence strategy of local humans, there was not any sign of raising pigs. Significant numbers of wild species including carnivores, aquatic mammals, and rodents, as well as resident and migratory birds, were also hunted by Alaybeyi people. Additionally, horse burials, horse cult, dog burials, and a rich number of dog bones present animals as versatile actors in various ritual and symbolic practices at the site.
Citation - WoS: 7
Citation - Scopus: 10
Antecedents of Gastronomy Destination Brand Equity: an Examination of Gastronomy Experience, Motivation, and Destination Satisfaction
(Akdeniz Univ, Tourism Fac, 2023) Kodas, Davut; Ozel, cagil Hale
This paper aims to test the relationships among gastronomic experience, motivation, destination satisfaction, and gastronomy destination brand equity. Data (n:600) was gathered from domestic visitors visiting Gaziantep in March, April to May 2018. Scale development to measure gastronomy experiences and scale adaptation process of destination brand equity were carried out. The relationships among the variables were examined with structural equation modeling. According to the findings, except H5 and H8, all hypotheses are significant in the research model. At the end of the study, significant theoretical and managerial implications were provided for the tourism providers and destination marketers, and managers.
Assessment of Children Exposed to Maras Powder Intoxication
(Folia Medica, 2020) Dalkiran, Tahir; Özaslan, Mehmed Mustafa; Acipayam, Can; Kandur, Yaşar; Unsal, Velid
Introduction: A smokeless tobacco known as Maras powder (MP) is commonly consumed in the southern region of Turkey. To the extent of our knowledge, no previous study in literature has reported acute MP intoxication in children. Aim: Our aim was to determine the clinical effects and treatment strategies of MP poisoning in children.Materials and methods: We retrospectively reviewed the medical records of children <18 years of age with MP intoxication who were followed up in the Intensive Care Unit between January 2016 and April 2018 in our center. Results: Forty-one patients (M/F= 25/16) were included in this study. The mean age was 13.2±22.4 months (age range: 7 to 30 months). The patients presented with vomiting (n=23, 56%), cough (n=17, 41.5%), loss of consciousness (n=11, 26.8%), respiratory distress (n=6, 14.6%), convulsion (n=7, 17%), cyanosis (n=1, 2.4%), and abdominal pain (n=1, 2.4%) following oral ingestion of the substance. On their physical examination all patients with convulsion were in a comatose state. Thirty-two patients (78%) had tachycardia; 15 patients (36.5%) had pharyngeal hyperemia; and three (7.3%) had hiccups. Although the female patients had a lesser rate of symptoms than male patients, the difference was not statistically significant. Conclusions: Our aim was to inform the doctors about the clinical picture that develops after taking this substance and contribute to the understanding of the treatment approach.
Citation - WoS: 9
Citation - Scopus: 10
Assessment of renal function in obese and overweight children with ngal and kim-1 biomarkers
(Nutricion Hospitalaria, 2020) Unsal, Velid; Gül, Ali; Yılmaz, Resul; Özmen, Zeliha Cansel; Demir, Osman; Gümüşer, Rüveyda
Aim and background:the incidence of obesity has increased among children, and obesity has been considered an independent risk factor for chronic kidney disease. We aimed to determine the degree of kidney function impairment by evaluating urine neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) levels. Materials and methods: in total, 15 obese, 26 overweight, and 26 control adolescents aged 10 to 16 years were enrolled into the study. Urine samples were evaluated for NGAL and KIM-1 levels using enzyme-linked immunosorbent assay kits. We investigated the association between obesity and related comorbidities with urinary NGAL and KIM-1 excretion. Results: no significant differences were noted between the obese, overweight, and control groups in urinary NGAL and KIM-1 excretion (p = 0.327 and p = 0.917, respectively). In the obese and overweight groups urinary NGAL levels were 50.39 [30.88-74.22] in females and 26.67 [23.24-45.59] in males (p = 0.013). Also, urinary NGAL levels were increased in obese and overweight adolescents with LDL dyslipidemia at 64.12 [30.98-114.32] as compared to those without LDL dyslipidemia: 39.51 [25.59.56.37] (p = 0.024). Furthermore, a correlation was observed between insulin and homeostasis model assessment of insulin resistance levels with the NGAL/creatinine ratio in the overweight group (r = 0.515; p = 0.008, and r = 0.483; p = 0.014, respectively). Such correlation was not found in the obese group. Conclusion: the effect of obesity on renal function could not be determined in children. A longer exposure may be required for obesity-induced disruption of renal function in children. Renal function may be disrupted by dyslipidemia in obese adolescents. Furthermore, obesity impaired renal function in female adolescents. The normalization of these urinary markers as related to urine creatinine should be discussed.
Citation - WoS: 8
Citation - Scopus: 6
The association of allergic rhinitis severity with neutrophil-lymphocyte and platelet-lymphocyte ratio in children
(Northern Clinics of İstanbul, 2022) Cansever, Murat; Sarı, Neslihan
Objective: The aim of the study was to investigate the relationship between the severity of allergic rhinitis (AR) and neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) in pediatric patients. Methods: This study is a retrospective, cross-sectional, and observational study including 200 AR patients and 160 healthy controls. Of the patients, 39% were boys with a mean age of 10.5 years. The study included children with persistent and intermittent AR. Of the controls, 50.6% were boys with a mean age of 10.3 years. We compared NLR and PLR from blood test between study and control groups. They were also compared according to AR severity within the patient group. Results: The NLR was 1.64±1.29 in the study group whereas 1.18±0.31 in the control group. The PLR was 102.72±31.20 in the study group whereas 79.36±11.72 in the control group. When NLR and PLR were compared between groups, we found statistically significant differences in both NLR and PLR (p=0.003, p=0.001, respectively). We found a statistically significant difference when comparing both NLR and PLR in patients with intermittent and persistent AR. These rates increased with disease severity (p=0.000, p=0.000, respectively). Conclusion: Both NLR and PLR are useful markers for the diagnosis and severity of AR. Clinicians can use these markers to assess disease severity in pediatric patients at the beginning of the diagnostic process.
Citation - WoS: 11
Citation - Scopus: 11
Biosensors for the Detection of Pathogenic Bacteria: Current Status and Future Perspectives
(Future Medicine Ltd, 2024) Dicle, Yalcin; Karamese, Murat
Pathogenic microorganisms pose significant threats to human health, food safety and environmental integrity. Rapid and accurate detection of these pathogens is essential to mitigate their impact. Fast, sensitive detection methods such as biosensors also play a critical role in preventing outbreaks and controlling their spread. In recent years, biosensors have emerged as a revolutionary technology for pathogen detection. This review aims to present the current developments in biosensor technology, investigate the methods by which these developments are used in the detection of pathogenic bacteria and highlight future perspectives on the subject. Microorganisms that cause disease are important not only to human health but also to food safety and environmental health. Therefore, it is important to detect these microorganisms quickly, easily, at a low cost and with accuracy. Biosensors have all of these features and offer a unique way to detect microorganisms. They are already being used in similar fields and are becoming increasingly portable and ergonomic devices. This paper looks at the uses of biosensors in detecting disease-causing bacteria and how their use will develop with greater technology. Outbreaks caused by pathogenic bacteria are a global concern, not only for human health but also for food safety and bioterrorism. This paper provides an overview of how biosensors can be used in the quick, easy and low-cost detection of pathogenic bacteria.
Citation - WoS: 1
Citation - Scopus: 2
Comparative Study of Lipid and Fatty Acid Profile in Liver Tissues of Male and Female Silurus triostegus During the Catching Seasons
(2021) Kaçar, Semra; Başhan, Mehmet
In this study, seasonal variations of total fatty acid (FA), phospholipid (PL) and triacylglycerol (TAG) compositions in liver tissues of catfish (Silurus triostegus) were investigated. Samples of S. triostegus were obtained from Atatürk Dam Lake, Turkey, in two month periods during one year as from May. The major components were palmitic acid (16:0), stearic acid (18:0), oleic acid (18:1n-9), palmi toleic acid (16:1n-7), docosahexaenoic acid (DHA, 22:6n-3) and arachidonic acid (AA, 20:4n-6) in total lipid, 16:0, 18:0, 18:1n-9, eicosapentaenoic acid (EPA, 20:5n-3), DHA and AA in PL, 16:0, 16:1n7, 18:1n-9, linoleic acid (LA, 18:2n-6), AA, EPA, DHA and docosapentaenoic acid (22:5n-3) in TAG extracted from the liver of S. triostegus in all seasons. N-3/n-6 ratio was found 2.00-2.61 in females, 1.15-2.75 in males in total lipid. The highest lipid content was found in May (2.39%) in the females. In the males, the highest level was found in September (2.91%). In TAG fraction, the component with the lowest ratio in both sexes’ TAG is PUFA. In PL fraction, SFA, MUFA, and PUFA percentages were found at similar rates in both sexes in all months.
Citation - WoS: 6
Citation - Scopus: 6
Cranial size and shape sexual dimorphism in the Kangal dog from Turkey
(Scientific and Technological Research Council of Turkey (TÜBİTAK), 2020) Pars-Casanova, Pere M.; Sıddıq, Abu Bakar; Onar, Vedat; Casanova, Pere Miquel Pares
This study has so far been the first attempt to characterize and quantify skull sexual variation in Kangal dog, by means of geometric morphometric techniques. A sample of 16 adult Kangal crania has been analyzed with this purpose. To obtain a full image of morphological pattern, digital pictures were taken from the ventral, left lateral, and dorsal sides of each skull, and a total of 16, 15, and 16 landmarks respectively were obtained on each image. Skull size and shape differed significantly in all aspects among different sexes, male skulls being bigger. Shape differences were observed mainly on zygomatic arch and muzzle on the dorsal view, pterygoid bone and articular surface to mandibular condyle in the lateral aspect, and cranial width and maxillary bone on the ventral view. Although the sample was comparatively small in number, being the first geometric morphometric approach applied on the Kangal dog, the obtained results will add vital information particularly to understand the cranial shape sexual dimorphism of this unique dog breed in Turkey.
DAĞ, SU VE MAĞARA KÜLTLERİ BAĞLAMINDA ANKARA HÜSEYİN GAZİ TÜRBESİ
(2017) Akyüz Öztokmak, Çiğdem
Yeryüzünü sabit tuttuğuna inanılması bakımından "yerin çivisi" ve yeryüzünün en yüksek noktalarını teşkil etmesi bakımından da "Tanrı'nın mekânı" olarak tasavvur edilen dağ, eski Türk inanç sistemlerinde bir kült olarak geleneksel pratikleri ve sosyal yaşamı şekillendirir. Dağ, aynı zamanda çağlayan nehirlerin, pınarların ve akarsuların kaynağını barındırır. Su ise maddi ve manevi yaşamın kaynağı ve idame ettiricisi olarak tüm inanışlarda kutsal kabul edilir. Bu bakımdan birçok kutsal anlatının dağ ve su etrafında teşekkül ettiği ifade edilebilir. Dağ, mağara ile birlikte kutsal kişiliklerin tefekkür mekânıdır. Nitekim Ankara'nın Mamak ilçesinde yaşadığı belirtilen Anadolu erenlerinden Hüseyin Gazi'nin bölgede kendi adı ile anılan bir dağ, bir türbe ve onun kutsal kişiliği ile ilintili anlatılar mevcuttur. Diyalektik bir etkileşimle hem dağı hem Hüseyin Gazi'yi kutsayan bu anlatılarda, su ve mağara kültleri de dikkati çeker. Söz konusu anlatılar, bölgedeki yükseltilerin isimlendirilmesi çerçevesinde kutsal dağ ve mağara metaforuna, bölgedeki su kaynaklarının menşei hakkında bilgiler vermesi bağlamında da kutsal su metaforuna atıf yapar. Bu çalışmada, Hüseyin Gazi etrafında teşekkül eden anlatılar, basılı kaynakların yanı sıra kaynak kişiler ile yapılan birebir mülakatlar yolu ile derlenerek dağ, su ve mağara kültleri bağlamında ele alınmıştır. Söz konusu anlatılardan mülhem tarihî kişiliklerin fenomenlere evrilmesi ve yer adlarının efsanevi menşei konusu irdelenmiştir. Bu kavramsal çerçevede Hüseyin Gazi hakkında anlatılagelen sözlü veriler, kutsal kişiliğinin, tarihî kişiliğinin önüne geçtiğini göstermiştir.
Citation - WoS: 3
Citation - Scopus: 4
Determination of Chemical Composition and Antioxidant, Cytotoxic, Antimicrobial, and Enzyme Inhibition Activities of Rumex Acetosella L. Plant Extract
(Springer int Publ AG, 2024) Kandemir, Sevgi Irtegun; Aktepe, Necmettin; Baran, Ayse; Baran, Mehmet Firat; Atalar, Mehmet Nuri; Keskin, Cumali; Khalilov, Rovshan; Irtegün Kandemir, Sevgi
Purpose The phenolic composition, antioxidant, antimicrobial activity, enzyme inhibition activity, and cytotoxic activity potentials of the plant Rumex acetosella L. (R. acetosella) were examined in this study. Materials and Methods: The chemical composition of R. acetosella methanol extract was identified by the LC-MS/MS method. The antioxidant activity was tested using beta-carotene/linoleic acid, DPPH free radical scavenging, ABTS cation radical scavenging, CUPRAC reducing power, and metal chelating activity methods. The cytotoxic activity was determined by the MTT assay using human ovarian adenocarcinoma (Skov-3), glioblastoma (U87), human dermal fibroblasts (HDF), and human colorectal adenocarcinoma (CaCo-2) cell lines. The antimicrobial activity of methanolic extracts was tested on gram-negative (Escherichia coli and Pseudomonas aeuriginosa) and gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis) using the in vitro minimum inhibition concentration method (MIC). Enzyme inhibition activity of R. acetosella methanol extract was measured spectrophotometrically against acetylcholinesterase (AChE) and glutathione S-transferase (GST) enzymes. Results: The findings showed that the major components of the methanol extract content were luteolin-7-O-glucoside (1.599 m/L), polydatin (91,024 m/L), and shikimic acid (0.773 m/L). It was determined that the extract and standard antioxidant (a-tocopherol) results in DPPH center dot, and ABTS center dot + tests performed to determine the antioxidant activity were close to each other, and this value was more effective than the standard antioxidant (alpha-tocopherol) in the CUPRAC test. These results suggested that the plant's antioxidant potential was higher when compared with reference antioxidant compounds. It was determined that the methanol extract of R. acetosella had a weaker effect on the growth of the tested microorganisms than the antibiotics used as standard. The activity of the GST and AChE enzymes was found to be severely inhibited by the methanol extract of R. acetosella. Conclusion: Based on these findings, R. acetosella L. is a medicinal and commercially beneficial plant that warrants further investigation.
Citation - WoS: 1
Determination of Women Voting Behavior: a Machine Learning Approach in the Turkish Political Arena
(Hipatia Press, 2020) Caha, Havva; Bayyurt, Nizamettin
Justice and Development Party (AKP) has been the ruling and biggest party in Turkey (AKP) since it has been established in 2002 and Republican People's Party (CHP) has been the main opposition party (CHP) since then. These two parties receive about 75% of all the votes. In Turkey half of the voters are females. In this study, the important attributes of women in party selection decisions are analyzed. To our knowledge, there is no such a study focusing on women's party preferences in Turkey. Additionally, this is one of the very few studies in Turkey concerning voters' party preferences. Therefore, this study aims to fill this gap in the literature. Center-periphery and social mobility theories are the two main theories explaining Turkish political life. The analyzed ideological, cultural, religious, social, economic and demographic characteristics of women supporters are selected according to these theories. Machine-learning techniques are employed as predictive tools. Results show that ideological attitudes like being leftist-rightist and religious values like headscarf, fasting in Ramadan, and praying are the most important effective attributes on party selection of women. However, socio-economic, cultural, educational and demographic atributes are not effective on party selection of women in Turkey.
Citation - WoS: 4
Citation - Scopus: 4
DEVELOPING THE ONLINE PORNOGRAPHY ADDICTION SCALE AND EXAMINING ITS ASSOCIATIONS WITH PSYCHOSOCIAL FACTORS
(Fundacion VECA, 2023) Ergün, Naif
This study aims to develop the Online Pornography Addiction Scale (OPAS) using the behavioral addiction model and to explore the relationships between the scale, demographic variables, psychosocial variables, and pornography viewing behaviors. Two studies were conducted, the first of which involved two phases. The findings from Study 1a and Study 1b reveal that the OPAS comprises 23 items organized into four sub-scales: Compulsiveness-Uncontrollability, Psychosocial Effects, Sexual Effects, and Tolerance-Withdrawal. Overall, the scale demonstrates consistency and reliability. The results of Study 2 indicate that the OPAS correlates with gender, access to professional support, levels of hopelessness, communication with partners, degree of religious affiliation, engagement with sexual videos, frequency of pornography consumption, time devoted to pornography viewing, longest duration without pornography, impact of pornography on sexual experiences, and influence of pornography on daily life. Communication with partners of the opposite sex, engagement with sexual videos, impact on daily life, and religious affiliation levels are also significant predictors of the OPAS score. These findings are discussed in relation to relevant literature
Citation - WoS: 5
Citation - Scopus: 5
Diagnostic Performance of Erythropoietin and Erythropoietin Receptors Levels in Children with Attention Deficit Hyperactivity Disorder
(Clinical Psychopharmacology and Neuroscience, 2021) Güngör, Meltem; Ergul Belge Kurutas, Erkan Oner, Velid Unsal, Hatice Altun, Ali Erdinc Yalin, Serap Yalin, Ozlem Bozkus, Nilfer Sahin
Objective: Attention deficit hyperactivity disorder (ADHD) is a heterogeneous, highly heritable, a common childhood neurobehavioural disorder resulting from complex gene-gene and gene-environment interactions. The erythropoietin (Epo)/erythropoietin receptors (EpoR) system turned out to have additional important functions in nonhematopoietic tissue. In this study, we aimed to investigate the levels of Epo and and EpoR, and also their diagnostic values in children with ADHD. Methods: A total of 70 children were included in the study, 35 drug-naive patients with ADHD (age: 6−12 years; male/female: 20/15) and 35 healthy controls (age: 6−12 years; male/female: 22/13). Serum Epo and EpoR levels was determined using a commercial sandwich enzyme-linked immunosorbent assay kit. Results: The results indicated that the levels of Epo decreased in patients with ADHD compared to control (p < 0.05). On the other hand, EpoR levels increased in these patients (p < 0.05). Furthermore, the ratio of Epo/EpoR was significantly lower in ADHD patients than controls (p < 0.05). Receiver operator characteristic curve analysis showed high diagnostic performance for Epo and EpoR, areas under curve were 0.980 and 1.000, respectively. Conclusion: This is the first report to investigate the association between serum Epo and EpoR levels in ADHD patients. Our results indicated that Epo may play a role in the etiology of ADHD, and Epo therapy may be beneficial in these disorders if given in addition to the routine treatment of children with ADHD. Furthermore, our results reveal possible diagnostic value of Epo and EpoR.
Citation - Scopus: 1
Dijital Beşerî Bilimler Bağlamında İlahiyat/İslâmî İlimler
(İstanbul Üniversitesi, 2022) Saraçoğlu, Tuba Nur
Son yıllarda dijital beşerî bilimler alanında görülen gelişmeler İslamî ilimleri de kapsayan proje ve çalışmalarla akademinin gündemini meşgul etmektedir. Genel anlamda dijital beşerî bilimler alanının tarihçesi, literatürü ve bu alanlardaki çeşitli çalışmalar Türkçe literatürde yer almıştır. Ancak İslamî ilimlerle ilgili yapılan çalışmalar ve projeler hakkında henüz bir metin kaleme alınmamış, bu alanlara ilgi duyan akademisyen ve araştırmacıların ihtiyacı olan bir yol haritası da henüz oluşturulmamıştır. Bu makalenin hedefi ilahiyat alanında dijital beşerî bilimlerin yöntemlerine ilgi duyan araştırmacılar için bir çerçeve sunmak ve bu alanla ilgili projelerden örnekler sunmaktır. Bu bağlamda elinizdeki makalede günümüze kadar ilahiyat alanında kullanılan dijital imkânlara, veri tabanları ve programlar çerçevesinde değinilecek ardından dijital beşerî bilimlerin çalışma süreçleri, İslamî ilimlerle irtibatlı olarak veri elde etme, veri temizleme, analiz ve görselleştirme kapsamında ele alınacaktır. Dijital beşerî bilimlerin bu alana getirdiği yeni araştırma yöntemleri ve alanla irtibatları ve İslamî ilimlerin geleceği açısından etkisi uzun süre devam edecek projeler de makale boyunca ilgili başlıklarda değerlendirilecektir.
Citation - WoS: 2
Citation - Scopus: 3
Does disability matter in counselling? Views of counsellors with visual disabilities and their clients
(British Journal of Guidance and Counselling, 2020) Sakız, Halis; Sarıcalı, Mehmet; Türküm, Ayşe Sibel
In this study we investigated the case of disability from the perspective of counsellors with visual disability (CWVD) and their clients by focusing on the counselling skills of CWVD, the relationships with their clients, and the perspectives of their clients in relation to their counselling experiences. Fifteen CWVDs and 11 clients (N = 26) were interviewed and data were analysed thematically. Findings show that CWVDs used their set of skills to build trustworthy therapeutic relationships through genuineness, established here and now relations in therapeutic encounter effectively, and produced meaningful outcomes. Findings of this research indicate the need to reconsider the field of counselling around pluralist, inclusive and multicultural paradigms.
Citation - Scopus: 5
Does oxidative status affect serum sclerostin levels in patients with type 2 diabetes mellitus?
(Folia Medica, 2023) Unsal, Velid; Ilhan Sabancilar, Fidel Demir, Gulten Toprak, Zafer Pekkolay
Introduction: Sclerostin is a glycoprotein known as a negative regulator of bone formation, predominantly expressed by mature osteocytes. There is no causative evidence information on the role of sclerostin in the pathogenesis of type 2 diabetes mellitus (T2DM) in humans. Aim: This study aimed to investigate the relationship between serum sclerostin levels and oxidative status and biochemical parameters in T2DM patients and healthy people. Materials and methods: This cross-sectional study, conducted in a clinical trial center, included 45 subjects with T2DM and 45 subjects as controls. Results: Serum sclerostin, total oxidative status (TOS), albumin, and ferritin levels were significantly higher in T2DM patients than in the control group (p<0.05). Total antioxidant status (TAS) was significantly higher in the control group (p<0.05). There was a weak positive correlation between sclerostin and TOS (r=0.23, p=0.03) and a weak negative correlation between sclerostin and TAS (r=-0.28, p=0.03). Conclusions: We have demonstrated that serum sclerostin levels increase in patients with T2DM and that the increased sclerostin levels are associated with oxidative stress.

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