Sağlık Hizmetleri Meslek Yüksekokulu

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Citation - WoS: 11
Citation - Scopus: 11
Anoxybacillus sp. SO B1-Immobilized Amberlite XAD-16 for Solid-Phase Preconcentration of Cu(II) and Pb(II) and Their Determinations by Flame Atomic Absorption Spectrometry
(TAYLOR & FRANCIS INC, 2015) Oral, Elif Varhan; Ozdemir, Sadin; Dolak, Ibrahim; Okumus, Veysi; Dundar, Abdurrahman; Ziyadanogullari, Berrin; Aksoy, Zehra; Onat, Ruken
A new method for the determination of Cu(II) and Pb(II) by flame atomic absorption spectrometry (FAAS) after preconcentrating on a column containing Anoxybacillus sp. SO B1-immobilized Amberlite XAD-16 was developed. The functional groups of Anoxybacillus sp. SO B1 immobilized on Amberlite XAD-16 were characterized in KBr tablets by Fourier transform infrared (FT-IR) spectrometry. Various parameters such as pH, amount of the adsorbent, eluent type and volume, and flow rate of the sample solution were studied. The optimum pH values of quantitative sorption for Cu(II) and Pb(II) were found to be pH 7.0 and 5.0 and Cu(II) and Pb(II) ions could be quantitatively eluted with 5.0ml of 1.0mol L-1 HCI and 10.0ml of 0.25mol L-1 HNO3, respectively. Recoveries of Cu(II) and Pb(II) were found to be 100.9 +/- 1.57% and 100.3 +/- 0.49% (N = 5), the limits of detection of Cu(II) and Pb(II) in the determination by FAAS (3s, N = 10) were found to be 0.8 and 1.6 mu g L-1, respectively. The proposed enrichment method was applied for metal ion determination from water samples such as two parts of Tigris River water in Diyarbakir and Elazig, Lake of Hazar in Elazig, and tap water in Diyarbakir. Furthermore, the accuracy of the proposed method was verified by studying the analytical recovery and by analyzing certified reference material (NCS-DC 73350 leaves of poplar).
Citation - WoS: 4
Citation - Scopus: 4
Application of Half-Sandwich Metal-Phosphinite Compounds to Biological Activities: Determine the energies of the HOMO and LUMO levels
(Wiley Online Library, 2022) Meriç, Nermin; Rafikova, Khadichakhan; Zazybin, Alexey; Güzel, Remziye; Kayan, Cezmi; Karakaş, Duygu Elma; Dündar, Abdurrahman; ISLAM, Sholpan; Okumuş, Veysi; Aydemir, Murat
Mononuclear transition metal complexes 1-(furan-2-yl)ethyldiphenyl[dichloro(η6-p-cymene)ruthenium(II)]phosphinite, (2), 1-(furan-2-yl)ethyldiphenyl[dichloro(η6-benzene) ruthenium(II)] phosphinite (3), 1-(furan-2-yl)ethyldipheny[chloro(η4-1,5-cyclooctadiene)rhodium(I)]phosphinite (4), 1-(furan-2-yl)ethyldiphenyl[dichloro (η5pentamethylcyclopentadienyl)iridium (III)] phosphinite (5) were synthesized and characterized by microanalysis, infrared, MS, and NMR spectroscopy. The biological activities of the complexes were also tested. Compounds 2 and 5 were the best complexes at DPPH radical scavenging and reducing power activity at 73.27 % and 0.41 at 200 μg/mL, respectively. The highest antimicrobial activity exhibited by complex 3 as 14 mm inhibition zone against S. aureus. All of the complexes have cleaved the DNA from the double-strand and exhibited three bands on gel electrophoresis. Moreover, cyclic voltammetry studies of the phosphinite complexes were carried out to determine the energies of the HOMO and LUMO levels as well as to estimate their electrochemical and some electronic properties.
The biochemical contents and antioxidant activities of four tanacetum L. taxa
(Progress in Nutrition, 2021) Emre, İrfan; Kürşat, Murat; Emre, Mustafa Yunus; Okkes, Yilmaz
The goal of the present study is to determine some of the biochemical compositions and antioxidant capacities of plant extracts in two endemic taxa for Turkey including T. cadmeum (Boiss.) Heywood subsp. orientale Grierson and T. nitens (Boiss. & Noë) Grierson together with T. polycephalum (L.) Sch.Bip subsp. argyrophyllum (K. Koch) Podlech, and T. parthenium (L.) Sch.Bip. The fatty acids were determined by using gas chromatography, while phenolics, lipid soluble vitamins and sterols were determined by using HPLC and radical scavenging activities, total phenolics, and FRAP were determined spectrophotometrically. It was found that Tanacetum taxa have palmitic acid (C16:0), and stearic acid (C18:0) as major saturated fatty acids and linoleic acid (C18:2 n6), α-linolenic acid (C18:3 n3) and oleic acid (C18:1 n9) as principal unsaturated fatty acids. It was found that Tanacetum taxa had more total unsaturated fatty acid contents (60.24±0.3%- 70.54±0.29%) than saturated fatty acids and it was found that T. parthenium had the highest total essential fatty acid composition (58.65%±0.59%). It was also reported that the omega6/omega3 ratio of T. cadmium subsp. orientale (8.22) differed from other taxa in this study. Also, the present study showed that Tanacetum had the lowest amount of lipid soluble vitamins. On the other hand, catechin was found to be the main polyphenolic compound in this study and it was determined that T. parthenium had the highest catechin (4479.1±5.71 µg/mg) and total phenolic contents (324.91±2.01 µgGAE/mg) in this study. Rutin was only determined in two endemic taxa T. cadmeum subsp. orientale (23±0.91 µg/mg), and T. nitens (5.7±0.27 µg/mg). Also, the naringenin, vanillic acid and caffeic acid amounts of the endemic T. cadmeum subsp. orientale and T. nitens were higher than other taxa in the study. In addition, it was determined that Tanacetum taxa had a high stigmasterol content. However, T. parthenium had a higher ergosterol content (271±2.36 µg/mg). It was also found that T. parthenium has highest D2, α-tocopherol, retinol acetate, ergosterol, and stigmasterol contents among the studied taxa. In addition, the study showed that Tanacetum taxa have strong DPPH and ABTS radical scavenging activities. It was concluded that Tanacetum taxa have potent antioxidant capacity.
Citation - WoS: 22
Citation - Scopus: 25
Biosorption of chlorophenoxy acid herbicides from aqueous solution by using low-cost agricultural wastes
(TAYLOR & FRANCIS INC, 2015) Okumus, Veysi; Celik, K. Serdar; Ozdemir, Sadin; Dundar, Abdurrahman; Kilinc, Ersin
The potential biosorption abilities of apple shell (AS), orange peel (OP), banana peel (BP), and millet waste (MW) as a bio-waste material to remove 2,4-dichlorophenoxy acetic acid (2,4-D), 2,4-dichlorophenoxy propanoic acid (2,4-DP), and 2,4-dichlorophenoxy butyric acid (2,4-DB) from aqueous solution were investigated in batch condition. Optimum biosorption conditions were determined as a function of contact time, pH of the solution, amount of biomass, and initial pesticide concentrations. The concentrations of the pesticides in the remaining solutions were simultaneously determined by high performance thin layer chromatography. Langmuir and Freundlich models were applied to describe the biosorption isotherm of the pesticides by agricultural wastes. The experimental adsorption data were fitted to Langmuir adsorption models (r(2)>0.99). It was found that adsorption of 2,4-DP was higher for all biosorbent. The highest maximum adsorption capacities of 2,4-DP were found as 40.08, 22.71, 33.26, and 45.45mg/g, respectively, for AS, OP, BP, and MW. Maximum adsorption capacity was obtained for 2,4-D as OP>MW>BP>AS, 2,4-DP as MW>AS>BP>OP, and 2,4-DB as OP>AS>BP>MW. From the results, it can be said that MW was an effective biosorbent for removal of 2,4-DP and OP was an effective biosorbent for removal of 2,4-D and 2,4-DB through the studied pesticides. Optimum biosorption conditions were determined as 60min of contact time, 100mg of biomass, AS at pH 6.0, OP at pH 6.0, MW at pH 7.0, and BP at pH 7.0. FT-IR was employed to understand the surface properties of biosorbents. According to the results, agricultural wastes have high adsorption capacity.
Citation - WoS: 8
Citation - Scopus: 3
Cardioprotective Effects of Hypericum Triquetrifolium Turra. Against Cyclophosphamide Related Cardiotoxicity in Rats
(Marmara Univ, 2018) Cetik Yildiz, Songul; Keskin, Cumali; Sahinturk, Varol; Ayhanci, Adnan
Cyclophosphamide (CYP) is commonly used as anticancer agent but its usage is limited by cardiotoxic side effects such as dose-dependent cardiac damage, morphologically defined necrosis and bleeding. Hypericum triquetrifolium Turra. (HT) shows anti-oxidative and anticarciogenic properties with its rich phenolic contents. The current study was designed to investigate the possible protective effect of HT on CYP-induced cardiotoxicity. Albino rats were randomly divided into 9 groups, each included 7 animals. Serum creatine kinase-MB (CK-MB), malondialdehyde (MDA), aspartate transaminase (AST), glutathione (GSH), total antioxidant (TAC) and total oxidant capacity (TOC) levels were investigated. Furthermore, the cardiac tissue samples were investigated histopatologically. While the levels of serum CK-MB, MDA, AST and TOC were high, the levels of serum GSH and TAC levels were low in the CYP groups. It was also observed that CYP-induced cardiotoxicity was dose dependent. In the treatment with CYP plus HT doses there was observed an essential decrease in the CYP cardiotoxicity; decreased cell damage and oxidative stress parameters and also increased GSH and TAC levels. Based on our findings, it can be proposed that HT seed methanol extract was a strong candidate in preventing the CYP-induced cardiotoxicity.
Citation - WoS: 2
Citation - Scopus: 3
Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS)
(Journal of Research in Pharmacy, 2022) Umaz, Adil; Firat, Aydin; Tokul Olmez, Ozge; Firat, Mehmet; Ertas, Abdulselame; Aydin, Isil
ABSTRACT: The importance of plants in folk medicine and scientific studies is increasing day by day. In this context, the plants pose a danger to human health when they are eaten by the public, consumed as herbal tea or used as medicinal plants especially the toxic metals in their composition. For this reason, determining the macro, micro and toxic element content in the plants is important for health. In this study; the metal contents of root and aerial parts of nine different Salvia species were determined and the chemometric evaluation of the obtained results was made. In the principal component analysis (PCA) made with 20 elements of Salvia species, it was determined that the first two principal components explained 62.60% of the variance and the first six principal components explained 92.70%. When PCA and hierarchical cluster analysis (HCA) results are evaluated; the parts of Salvia species root and aerial parts were determined that were not clearly separated and there was no regional grouping. In addition, Salvia species prepared as herbal tea was left to different simulated body fluid medium conditions, and the changes in metal contents were examined. It was determined that were taken up Cr, Cd, Pb, Cu, Zn metals in the simulated saliva fluid (SSF), Ni, Mn metals in the simulated gastric fluid (SGF), and Na, K metals in the simulated intestinal fluid (SIF). It was determined that Fe metal in almost all Salvia species was not taken from three simulated body fluid mediums. Thus, elements determined which were taken up in body fluid mediums.
Citation - WoS: 5
Citation - Scopus: 5
Determination of Zinc in Dried Nuts by Slotted Quartz Tube-Flame Atomic Absorption Spectrometry (SQT-FAAS) With Citric Acid-Coated Magnetic Nanoparticle (CAMNP) Based Solid Phase Extraction (SPE)
(Taylor & Francis Inc, 2025) Umaz, Kader; Umaz, Adil; Aydin, Isil; Aydin, Firat
This study reports a sensitive method for trace zinc using slotted quartz tube-flame atomic absorption spectrometry (SQT-FAAS) with citric acid-coated magnetic nanoparticle-solid phase extraction (CAMNP-SPE). To increase the efficiency, we univariately optimized the pH, buffer volume, CAMNP mass, eluent concentration and volume, mixing type and time, temperature, and interaction time. The study identified the limits of detection and quantification values for CAMNP-SPE-SQT-FAAS under the specified optimum conditions to be 12.30 and 41.00 mu g L-1, respectively. The newly developed method improved the detection power of traditional FAAS by 13.25 times. The findings of this study report a sensitive and accurate method to determine trace zinc in complex matrices.
Citation - WoS: 4
Citation - Scopus: 6
Evaluation of Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and C-Reactive Protein in Tension-Type Headache Patients
(Journal of Neurosciences in Rural Practice, 2021) Özdemir, Hasan Hüseyin; Dönder, Ahmet
Objectives A tension headache is the most common type of headache, and its causes are multifactorial. A relationship has been shown between migraine headaches and neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and C-reactive protein (CRP). In this study, we investigated the NLR, PLR, and serum CRP levels in frequent episodic tension-type headache (FETTH) and chronic tension-type headache (CTTH) patients. Materials and Methods This retrospective study included 64 patients with FETTH, 80 patients with CTTH, and 60 healthy controls who were followed up in the neurology clinic. Hematological parameters were compared between the patient and control groups. Results In CTTH patients, platelets, NLR, PLR, and CRP values were statistically higher than in FETTH patients and patients in the control group. In FETTH patients, the PLR value was higher than in patients in the control group, but there was no statistically significant difference in NLR and CRP values between FETTH patients and patients in the control group. Also, there was no correlation between these values and age and gender. Conclusion Increase platelet count might have an effect on tension-type headache pathophysiology. Systemic inflammation parameters were shown to be significantly higher in CTTH patients. More comprehensive studies are needed to evaluate the effect of systemic inflammation on the chronicity of tension headaches.
Citation - WoS: 3
Fast and Economical Biosorption of Lead (II) Heavy Metal in Aqueous Solutions by Bacillus licheniformis sp.
(Kahramanmaraş Sütçü İmam Üniversitesi, 2022) Baran, Mehmet Fırat; Düz, Zahir; Baran, Ayşe; Keskin, Cumali
Lead is used in many areas of industry. Considering the prevalence of use, there is an intense lead and heavy metal content in the wastes resulting from these applications, and the toxic pollution caused by these metals affects the nearest water source directly or indirectly. Lead poses a serious threat to all life forms in the ecosystem, even at low concentrations in water. Lead recovery with environmentally friendly methods is both easier and more economical. Bacillus licheniformis sp. type was used as a biosorbent in the study. Nearly 98.4% of lead was removed by using the batch biosorption method, at 25 oC, pH 5.5, with an adsorption capacity of 42.92 in 120 minutes. from the water. The properties of the biosorbent, such as its morphological appearance, were characterized by scanning electron microscopy (SEM). Besides, the functional groups affecting biosorption in the surface structure were investigated by fourier transform Infrared spectroscopy (FT-IR)while its resistance to heat treatment was measured by thermal gravimetric analysis (TGA-DTA). The lead(II) element content in the aqueous solution was also determined by inductively coupled plasma optical emission spectroscopy (ICP-OES).
Citation - WoS: 6
Citation - Scopus: 6
Increased visinin-like protein-1, YKL-40, lipocalin-2, and IL-23 levels in patients with migraine
(Taylor & Francis Online, 2022) Dündar, Ahmet; Cafer, Vugar; Aslanhan, Hamza; Özdemir, Hasan Hüseyin; Yilmaz, Ahmet; Çevik, Mehmet Uğur
Background: Migraine is a type of primary headache caused by changes in the trigeminal system and has been reported to be associated with neurovascular inflammation of cerebral and extracerebral vessels. Objective: It is known that inflammation is an important process in the pathogenesis of migraine. It has been shown that the molecules of visinin-like protein 1 (Vilip-1), YKL-40, lipocalin-2 and interleukin (IL)-23 play a role in the inflammatory process. Our aim is to investigate the role of this molecule in the metabolic pathway of migraine disease. Methods: Fifty migraine patients with and without aura in the interictal period were included in the study. Vilip-1, YKL-40, lipocalin-2, and IL-23 levels were measured by ELISA method. Results: Serum vilip-1, YKL-40, lipocalin-2, and IL-23 levels were found to be significantly higher in migraine patients compared to the control group. We found that this molecule increased significantly in migraine subgroups compared to the control group (p < 0.001). A positive significant correlation was found between vilip-1 level and YKL-40 and lipocalin-2 levels in migraine patients. In addition, a positive correlation was observed between visual analogue scale score, number of days with pain and vilip-1 level (p < 0.01). The results of our study showed that activation of inflammatory mediators may play a role in the pathogenesis of migraine disease. In addition, our study is valuable in that inflammatory molecules are high in the interictal period and these biomarkers have never been analyzed in migraine patients. However, we still believe that larger studies are needed to explain the role of vilip-1, YKL-40, lipocalin-2, and IL-23 in the molecular mechanism of migraine disease.
Citation - WoS: 1
Citation - Scopus: 1
Investigate Nasal Colonize Staphylococcus Species Biofilm Produced
(Derman Medical Publ, 2015) Demir, Cemil; Inanc, Betul Battaloglu
Aim: 127 S. aureus and 65 CoNS strains were isolated from patients noses'. To produce a biofilm ability was investigated using three different methods. Slime-positive and negative staphylococcies' resistance were evaluated against different antibiotics. Material and Method: Swap samples puted 7% blood agar. Staphylococcus aureus and coagulase-negative staphylococci (CoNS) isolates biofilm produced ability were investigated using Congo Red Agar (CRA), microplates (MP) and Standard Tube (ST) methods. In addition to that, presence of antibiotic resistance of the staphylococcal isolates are determined agar disc diffusion method. Results: The rate of biofilm producing Staphylococcus spp strains was found to be 72.4%, 67.7%, and 62.9%, respectively with CRA, MP, and ST tests. There was no significant relationship among the tests (p>0.05). In addition, antibiotic resistance of Staphylococcus spp. against various antibiotics was also determined by the agar disk diffusion method. Resistance rates of biofilm positive (BP) Staphylococcus spp for penicilin G, ampicilin, amocycilin/clavulanic acid, tetracyclin, eritromycin, gentamycin, and enrofloxacin 71.7%, 69.7%, 6.2%, 20.7%, 21.4%, 1.4%, and 0.7%, respectively. Resistance rates of biofilm negative (BN) spp for 42.6%, 23.4%, 4.3%, 14.9%, 19.1%, 0.0%, 0.0% respectively. All Staphylococcus isolates were found to be susceptible to vancomycin and teicaplonin. Although BP strains antibiotic resistance rates were observed higher than BN strains. But resistance rates were not found statistically significant (p>0.05). Discussion: CRA is the reliablity and specifity method to determine Staphylococcus spp. biofilm produce ability.
Citation - WoS: 3
Investigation of Uroprotective Effects of Seed Methanol Extracts of Hypericum Triquetrifolium Turra. on Cyclophosphamide-Induced Bladder Hemorrhagic Cystitis and Nephrotoxicity in Wistar Albino Rats
(Cukurova Univ, Fac Medicine, 2020) Yildiz, Songul Cetik; Keskin, Cumali; Sahinturk, Varol; Ayhanci, Adnan
Purpose: This study investigated the possible uroprotective effects of Hypericum triquetrifolium Turra. (HT) seed methanol extracts (25,50,100 mg/kg, i.p., for 6 days) against cyclophosphamide (CYP)-induced (150 mg/kg, single dose, i.p.) acute bladder hemorrhagic cystitis (HC) and nephrotoxicity in rats. Materials and Methods: Wistar albino rats used in this study were divided into nine groups, each including seven rats. Group 1 (control) was treated with 0.5ml saline (SF) and Group 2 was treated with CYP (150 mg/kg). Groups 3, 4, 5 were treated with 25, 50, 100 mg/kg HT, respectively while groups 6, 7, 8 were treated with 25, 50, 100 mg/kg CYP + HT, respectively. Finally, Group 9 (control-2) was treated with 0.5ml-%0.2 dimethyl sulfoxide (DMSO). The serum creatinine, blood urea nitrogen (BUN), superoxide dismutase (SOD) and catalase (CAT) levels were measured in blood serum. Results: The CYP-treated rats histopathologically had mild-moderate bladder and renal injuries. The serum creatinine and BUN levels, which are the biochemical markers of renal injury, significantly increased compared to the control group. Conclusion: HT showed a protective effect on CYPrelated bladder HC and nephrotoxicity in rats by inhibiting inflammation and apoptosis.
Investigation of Uroprotective Effects of Seed Methanol Extracts of Hypericum Triquetrifolium Turra. on Cyclophosphamide-Induced Bladder Hemorrhagic Cystitis and Nephrotoxicity in Wistar Albino Rats
(Cukurova Univ, Fac Medicine, 2020) Yildiz, Songul Cetik; Keskin, Cumali; Sahinturk, Varol; Ayhanci, Adnan
Purpose: This study investigated the possible uroprotective effects of Hypericum triquetrifolium Turra. (HT) seed methanol extracts (25,50,100 mg/kg, i.p., for 6 days) against cyclophosphamide (CYP)-induced (150 mg/kg, single dose, i.p.) acute bladder hemorrhagic cystitis (HC) and nephrotoxicity in rats. Materials and Methods: Wistar albino rats used in this study were divided into nine groups, each including seven rats. Group 1 (control) was treated with 0.5ml saline (SF) and Group 2 was treated with CYP (150 mg/kg). Groups 3, 4, 5 were treated with 25, 50, 100 mg/kg HT, respectively while groups 6, 7, 8 were treated with 25, 50, 100 mg/kg CYP + HT, respectively. Finally, Group 9 (control-2) was treated with 0.5ml-%0.2 dimethyl sulfoxide (DMSO). The serum creatinine, blood urea nitrogen (BUN), superoxide dismutase (SOD) and catalase (CAT) levels were measured in blood serum. Results: The CYP-treated rats histopathologically had mild-moderate bladder and renal injuries. The serum creatinine and BUN levels, which are the biochemical markers of renal injury, significantly increased compared to the control group. Conclusion: HT showed a protective effect on CYPrelated bladder HC and nephrotoxicity in rats by inhibiting inflammation and apoptosis.
Citation - WoS: 30
Citation - Scopus: 37
Mononuclear Complexes Based on Pyrimidine Ring Azo Schiff-Base Ligand: Synthesis, Characterization, Antioxidant, Antibacterial, and Thermal Investigations
(WILEY-V C H VERLAG GMBH, 2014) Gulcan, Mehmet; Ozdemir, Sadin; Dundar, Abdurrahman; Ispir, Esin; Kurtoglu, Mukerrem
Six transition metal(II) complexes with the heterocyclic ligand HL (1), [CuL2]center dot H2O (2), [NiL2]center dot 3H(2)O (3), [CoL2]center dot 3H(2)O (4), [MnL2]center dot 3H(2)O (5), [ZnL2]center dot 2H(2)O (6), [PdLOAc]center dot H2O (7) [HL = 5-benzoyl-1-((E)-(2-hydroxy-5-((E)-phenyldiazenyl)benzylidene)amino)-4-phenylpyrimidin-2(1H)-one] were synthesized. The features of the azo Schiff bases were assigned from microanalytical, spectroscopic (IR, UV/Vis., H-1- and C-13 NMR, API-ES mass), magnetic, and molar conductivity measurements at room temperature as well as thermal analysis. The electronic absorption spectroscopy and magnetic susceptibility measurements of the complexes indicate square pyramidal arrangement for Pd-II and octahedral environment for all the other complexes. The azo Schiff base HL acts as a monobasic tridentate ligand, which commonly coordinates through the oxygen atoms of the phenol OH and the pyrimidine one group, and the nitrogen atom of the azomethine group. The thermal behaviors of the ligand and its metal complexes were studied using thermogravimetric analysis (TGA) and differential thermal analysis (DTA). The metal complexes proved to be more thermally stable than the ligand; they decomposed at 10-30 degrees C higher temperatures. Antioxidant properties of the ligand and its metal complexes (DPPH free radical scavenging, ferrous chelating and reducing power activities) were tested. Antimicrobial activities were studied with gram-positive bacteria, which included Bacillus subtilis and Staphylococcus aureus, whereas Escherichia coli and Pseudomonas aeruginosa represented gram negative bacteria.
Multi-Faceted Evaluation of Psychosocial Function of Elderly Subjects
(Cyprus Journal of Medical Sciences, 2022) Vural Doğru, Birgül; Utli, Hediye
BACKGROUND/AIMS: With aging, physical, psychological and social changes occur and individuals lose their independence and become semi-or full dependent. Accordingly, physical, psycho-social problems can be seen in the older people and their functionality decreases. For this reason, the study was carried out for the purpose of multidimensional evaluation of cognitive and psycho-social functions of older people. MATERIALS and METHODS: The study was conducted between April 2018 and November 2018. This descriptive and cross-sectional study was performed in two different family health centers in Mardin province. The research was completed with a total of 200 older people who agreed to participate in the study. The data were collected using “Patients Information Form”, “Katz Index of Independence in Activities of Daily Living (Katz ADL)” and “Multidimensional Observation Scale for Elderly Persons (MOSES)”. The number, percent, mean, Mann-Whitney U, Kruskal-Wallis test and Spearman correlation analysis were used in the data analysis. RESULTS: The mean age of participants was 70.03±8.48 years. 54.2% of older people were female and 45.8% were male. The mean score of Multidimensional Observation Scale for Elderly Persons was 24.36±22.38. The mean score of the Katz Index of Independence in Activities of Daily Living was 16.32±3.14. There was a weak positive correlation between age and Multidimensional Observation Scale for Elderly Persons (p<0.001, r=0.43), and a moderate negative correlation was found between Katz Index of Independence in Activities of Daily Living and MOSES (p<0.001, r=-0.56). CONCLUSIONS: This study revealed that older people had high functional and independence levels, and this is due to the fact that older people who come to family health care centers form a sample group. However, multidisciplinary studies periodically are needed to evaluate the cognitive, psychological and social functioning of older people living at home.
Citation - WoS: 12
Citation - Scopus: 14
Preconcentration with Bacillus subtilis-Immobilized Amberlite XAD-16: Determination of Cu2+ and Ni2+ in River, Soil, and Vegetable Samples
(TAYLOR & FRANCIS INC, 2015) Okumus, Veysi; Ozdemir, Sadin; Kilinc, Ersin; Dundar, Abdurrahman; Yuksel, Uyan; Baysal, Zubeyde
Solid-phase extraction (SPE) method was developed for the preconcentration of Cu2+ and Ni2+ before their determination by inductively coupled plasma optical emission spectrometry (ICP-OES). Bacillus subtilis-immobilized Amberlite XAD-16 was used as biosorbent. Effects of critical parameters such as pH, flow rate of samples, amount of Amberlite XAD-16 and biosorbent, sample volume, eluent type, and volume and concentration of eluent on column preconcentration of Cu2+ and Ni2+ were optimized. Applicability of the method was validated through the analysis of the certified reference tea sample (NCS ZC73014). Sensitivity of ICP-OES was improved by 36.4-fold for Cu2+ and 38.0-fold for Ni2+ by SPE-ICP-OES method. Limit of quantitation (LOQ) was found to be 0.7 and 1.1ng/ml for Cu2+ and Ni2+, respectively. Concentrations of Cu2+ and Ni2+ were determined by ICP-OES after application of developed method. Relative standard deviations (RSDs) were lower than 4.9% for Cu2+ and 7.9% for Ni2+. The Tigris River that irrigates a large agricultural part of Southeast Turkey is polluted by domestic and industrial wastes. Concentrations of Cu2+ and Ni2+ were determined in water, soil, and some edible vegetables as a biomonitor for heavy metal pollution.
Citation - WoS: 12
Citation - Scopus: 13
Protective properties of kefir on burn wounds of mice that were infected with S. aureus, P. auroginasa and E. coli
(Cellular and Molecular Biology (CMB), 2019) Çetik Yıldız, Songül; Demir, Cemil; Cengiz, Mustafa; Ayhanci, Adnan
Burns and burn wounds are very sensitive to infections and cause a large amount of death worldwide. Although burn wound is sterile at the beginning, because of the risk factors such as prolonged hospital stay, immune suppression and burn affecting large surface area, colonisation with Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli occur. For the burn therapy, one of the most important ways is to control bacterial infections. A probiotic fermented milk product kefir has antioxidant, antimicrobial, antiinflammatory, anticancer and various health promoting features. This study aims to examine possible protective properties of kefir which was used on the burn wounds that were infected with S. aureus, P. auroginasa and E. coli. Swiss albino / Balb-c mice were seperated into four groups: (1) used as control group, (2) second-degree burn model+ burn wounds were infected with P.aeruginosa + S.aureus + E.coli, (3) second-burn wounds were treated with sterile pads dressed with kefir and (4) second-degree burn+burn wounds were infected with P. aeruginosa + S.aureus +E.coli before being treated with sterile pads dressed with kefir. The serum biochemical results verified the histopathological results and our findings showed that kefir is an effective product with cell-protecting properties.
Citation - WoS: 28
Citation - Scopus: 29
Removal of 17β-estradiol from aqueous systems with hydrophobic microspheres
(Journal of Polymer Engineering, 2021) Alacabey, İhsan; Kireç, Osman; Alkan, Hüseyin; Erol, Kadir
Sub-microparticles have many applications in different fields today. In this study, it is aimed to develop hydrophobic microparticles as an alternative to existing methods and to determine the 17β-estradiol adsorption performance of this adsorbent to purify the 17β-estradiol hormone which is found as an endocrine disruptor in environmental waters with high capacity and low cost. In this study, L-phenylalanine containing Poly(HEMA-MAPA) microparticles were synthesized by microemulsion polymerization and used as adsorbent. Microparticles were characterized by Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscope (SEM) methods. The size of the Poly(HEMA-MAPA) microparticles used was measured as 120-200 nm. Specific surface area and elemental analysis studies were also conducted. While the surface area of the particles was found to be a very high value of 1890 m2/g, the amount of incorporation of MAPA into the polymeric structure was calculated as 0.43 mmol/g. Adsorption studies were carried out in the batch system under different ambient conditions (17β-estradiol concentration, temperature, ionic intensity). The adsorption capacity of Poly(HEMA-MAPA) microparticles was calculated to be 98.4 mg/g. Isotherm models for adsorption interaction were investigated deeply, and it was determined that the adsorption mechanism is suitable for Langmuir isotherm.
Citation - WoS: 28
Citation - Scopus: 27
Removal of cadmium (II) in the aqueous solutions by biosorption of Bacillus licheniformis isolated from soil in the area of Tigris River
(International Journal of Environmental Analytical Chemistry, 2021) Baran, Mehmet Fırat; Duz, Mehmet Zahir
Biosorption by dead bacteria is an alternative and effective method for the removal toxic elements from drinking water and waste water. The biosorption of Cd(II) from aqueous solutions was studied in a batch method by using dead bacteria Bacillus licheniformis sp. extracted from soil in the area of Tigris River. The Cd element analysis was determined using ICP-OES and AAS. The maximum adsorption capacity of biosorbent was determined, respectively, 24.51 mg/g for Cd element from Langmuir isotherm constants in the optimum conditions. The characterisation of B. licheniformis to describe behaviour of bacteria was determined such as adsorption isotherm, kinetic and thermodynamic data using FT-IR, TGA, DTA, SEM and EDX. The results suggested that the most equilibrium data of Cd(II) bioadsorption was best represented by the pseudo second-order equation and Langmuir isotherm model at different time-temperatures. The thermodynamic functions and activation energy was found to be ΔG°; −0,984 kJ/mol at 318 K, ΔH°; 15.48 kJ/mol, ΔS°; 39.08 kJ/mol and Ea; 23.24 kJ/mol and due to the ΔG°< 0, ΔH°> 0, ΔS°> 0, the reaction mechanism was determined to be physical adsorption and endothermic. This study shows that B. licheniformis sp. can be used as an effective method for the removal of Cd(II) from aqueous solutions.
Citation - WoS: 26
Citation - Scopus: 24
Removal of hazardous azo dye Metanil Yellow from aqueous solution by cross-linked magnetic biosorbent; equilibrium and kinetic studies
(Taylor & Francis Online, 2016) Tural, Servet; Tarhan, Tuba; Tural, Bilsen
In this study, glutaraldehyde cross-linked magnetic chitosan nanoparticles (GMCNs) were prepared through cross-linking modification of magnetic chitosan nanoparticles using glutaraldehyde as a cross-linker that exhibited excellent Metanil Yellow (MY) adsorption performance. The characterization of the GMCNs was performed by Fourier transform infrared spectroscopy, transmission electronmicroscopy, scanning electron microscopy, dynamic light scattering, and vibrating sample magnetometry analyses. Adsorption characteristics of MY from aqueous solution onto GMCNs have been studied. During the studies, various essential factors influencing the adsorption, like adsorbate concentration, amount of adsorbent, pH of the solution, and contact time have been monitored. The equilibrium was achieved within 17 h at pH 4, and the adsorption data obeyed the Langmuir equation with a maximum adsorption capacity of 625 mg/g and a Langmuir adsorption equilibrium constant of 5.2 × 10−4 dm3/mg at 25°C. The adsorption kinetics of MY at different initial dye concentrations was evaluated by the first-order and second-order models. The kinetic studies of MY adsorption showed that the adsorption process followed a second-order kinetic model. Furthermore, the GMCNs can be regenerated and reused through dye desorption in alkaline solution at pH 10. Adsorption results for reusability were 100, 93, and 65%, respectively, for three repeats.

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