Talay, Mehmet Nur

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Talay, Mehmet N.
Talay, M.N.
Job Title
Dr. Öğr. Üyesi
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Main Affiliation
Department of Internal Medical Sciences / Dahili Tıp Bilimleri Bölümü
Status
Current Staff
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Scopus Author ID
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WoS Researcher ID

Sustainable Development Goals

3

GOOD HEALTH AND WELL-BEING
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3

Research Products
This researcher does not have a Scopus ID.
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Scholarly Output

14

Articles

12

Views / Downloads

47/260

Supervised MSc Theses

0

Supervised PhD Theses

0

WoS Citation Count

4

Scopus Citation Count

3

WoS h-index

1

Scopus h-index

1

Patents

0

Projects

0

WoS Citations per Publication

0.29

Scopus Citations per Publication

0.21

Open Access Source

8

Supervised Theses

0

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JournalCount
Archivos Argentinos de Pediatria4
Pediatric Pulmonology2
Egyptian Pediatric Association Gazette1
Fetal and Pediatric Pathology1
Iranian Journal of Pediatrics1
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Scholarly Output Search Results

Now showing 1 - 10 of 14
  • Article
    Citation - WoS: 2
    Citation - Scopus: 1
    Evaluation of the Results of the Patients Who Underwent Plasmapheresis in the Pediatric Intensive Care Unit
    (Tubitak Scientific & Technological Research Council Turkey, 2024) Talay, Mehmet Nur; Orhan, Ozhan; Kangin, Murat; Turanli, Ese Eda; Ozbek, Mehmet Nuri
    Background/aim: Therapeutic plasma exchange (TPE) is an extracorporeal treatment method that removes large molecular weight substances from plasma. In our study, we aimed to retrospectively examine the indications and procedural methods of the patients who had undergone TPE, and the complications that occurred during the procedure. Materials and methods: Forty-one patients who were monitored in thePICU of Gazi Ya & scedil;argil Training and Research Hospital and had indications for TPE between 2017 and 2021 were included in the study. Laboratory parameters were checked before and after the TPE procedure. In addition to these, patients' diagnosis, weight, type of procedure and type of device, where the procedure was performed, duration of the procedure, amount of blood and plasma processed, complications, number of procedures, and death during the procedure or independent of the procedure were evaluated. Results: The median age was 93.0 (14.0-167.0) months. Hemolytic uremic syndrome (HUS) was the most common TPE indication with nine patients. The most common complication related to TPE was fever (11 patients), while no complication was observed in 18 patients. When laboratory results were evaluated according to American Society for Apheresis (ASFA) categories, a significant improvement was observed in the values of platelet, AST, ALT, LDH, urea, and creatinine in ASFA1 after TPE. No significant improvement was observed in ASFA2 (p > 0.05). In ASFA3, a significant improvement was observed in INR, AST, ALT, LDH, total bilirubin, creatinine, pH, and lactate values after TPE (p < 0.05). Five patients died from ASFA1, one from ASFA2, and three patients from ASFA3. Conclusion: Since significant adjustments are observed in clinical and laboratory values in sepsis-MOF, which is in the ASFA3 category, we believe that it should be evaluated in the ASFA2 or ASFA1 category in the early treatment of these diseases. In addition, we think that MIS -C cases, which have not been in any category according to ASFA, should be included in the ASFA2 or ASFA3 category, considering our TPE results.
  • Article
    Evaluation of Cardiac Functions in Neonates With Hypoxic Ischemic Encephalopathy
    (Taylor & Francis Inc, 2025) Sero, Leyla; Tuncel, Duygu; Talay, Mehmet Nur; Karaca, Mehmet Salih; Gul, Ozlem; Okur, Nilufer
    Introduction: The aim of our study was to evaluate the role of cardiac markers in determining prognosis in newborns with Perinatal Asphyxia (PA). Method: Patients with a pH <7-7.15 base deficit -12> mmol/L were defined as PA. NT-proBNP, cardiac Troponin I (cTnI), creatine kinase MB levels were analyzed. Patients with excitus during follow-up were compared with patients with pathological MRI findings and cardiac markers. Results: A total of 115 infants with perinatal asphyxia were included in the study.cTnI levels was median 0.63 (min 0.1-max 4.2) ng/ml significantly higher in patients who died (p = .006). The predictive power of cTnI was evaluated and the threshold value of cTnI for predicting mortality was determined as 0.428 ng/ml with 87.5% sensitivity and 87.2% specificity. Conclusion: We found that cTnI level analyzed in the first hours of life in newborn infants with PA has value in predicting both mortality and cranial affections.
  • Letter
    An Unexpected Cause of Tension Pneumothorax: A Case Report
    (John Wiley and Sons Inc, 2025) Talay, M.N.; Sızlanan, A.; Gungor, E.; Kalkan, F.; Orhan, Ö.; Nayir-Buyuksahin, H.
  • Article
    Acute Cyanide Poisoning Due To Ingestion of Apricot Seeds
    (Soc Argentina Pediatria, 2024) Talay, Mehmet N.; Gungor, Emre; Orhan, Ozhan
    [No Abstract Available]
  • Article
    Metahemoglobinemia y hemolisis intravascular aguda despues de una intoxicacion por naftaleno en un paciente pediatrico
    (Soc Argentina Pediatria, 2023) Orhan, Ozhan; Talay, Mehmet N.
    [No Abstract Available]
  • Article
    Methemoglobinemia and acute ıntravascular hemolysis after naphthalene poisoning in a pediatric patient
    (SciELO Argentina, 2023) Orhan, Özhan; Talay, Mehmet Nur
    Poisoning by naphthalene is uncommon in children. It is a type of poisoning brought on by ingesting, inhaling, or coming into touch with naphthalene-containing substances on the skin. Patients typically present with an initial onset of dark brown urine, watery diarrhea, and bile vomit. The signs include fever, tachycardia, hypotension, and low pulse oximetry readings even with oxygen support. Hemolytic anemia, methemoglobinemia, renal failure, and hyperbilirubinemia are all detected in blood tests. Erythrocyte transfusion, ascorbic acid, methylene blue, and N-acetylcysteine (NAC) therapies are provided to inpatients in addition to symptomatic treatment. We present a 23-month-old male patient who developed methemoglobinemia and acute ıntravascular hemolysis, who was followed up in the intensive care unit for five days due to naphthalene intoxication. Although naphthalene poisoning is very rare, it should be known that it has fatal consequences, and more care should be taken in its use and sale
  • Article
    Our Treatment Experience in Poisoning With Calcium Channel Blockers: a Series of Twelve Cases
    (Briefland, 2024) Talay, Mehmet Nur; Orhan, Ozhan; Ozbek, Mehmet Nuri; Kangin, Murat; Turanli, Ese Eda
    Background: Intoxications with cardiovascular system drugs constitute a small percentage of all poisoning cases. Calcium Channel Blockers (CCBs) are the most common drug poisoning in this group. Objectives: We aimed to evaluate the effectiveness of treatments for CCB poisoning and add to the current body of literature by outlining the clinical treatments we employ for bradyarrhythmia, hypotension, and resistant vasodilation resulting from CCB poisoning, as well as sharing our clinical insights in this field. Methods: Twelve patients, ranging in age from 1 month to 18 years, were admitted to the Tertiary Paediatric Intensive Care Unit (PICU) for treatment of medication poisoning related to the CCB group. Patients who ingested several drugs that caused CCB were not allowed to participate in the trial. Results: Twelve patients were followed up in the PICU due to poisoning with CCB group drugs. Of the patients, 7 were male and 5 were female. Five of the patients had taken CCB medication with the purpose of committing suicide, and 7 of them accidentally. All of the patients who received CCB to commit suicide had taken verapamil. Five patients whose hypotension and bradycardia continued were administered inotropes. In addition to PI, calcium gluconate, intravenous lipid, glucagon, insulin, bicarbonate, and methylene blue were given as therapy to our symptomatic patients. Plasmapheresis was applied to a patient who was hospitalized in the PICU due to a sudden loss of consciousness. Conclusions: In the management of patients with CCB poisoning, the use of hyperinsulinemia euglycemia, intravenous lipid emulsion treatment, glucagon treatments, and treatments including methylene blue and extracorporeal life support should be considered in cases of resistant hypotension, bradycardia, and coma in the early period.
  • Article
    Citation - WoS: 1
    Citation - Scopus: 1
    Evaluation of Measles Cases in a Province in South-Eastern Turkey Receiving Migration From Syria
    (Wiley, 2025) Orhan, Ozhan; Solmaz, Murat; Talay, Mehmet Nur
    Aim: The study aimed to compare the demographic, clinical and vaccination status of measles cases in 2023 in our region receiving migration from Syria and to evaluate the effect of migration on disease dynamics. Methods: This retrospective study analysed the demographic profiles, clinical features and vaccination status of a total of 98 (67 children born and raised in Turkey [group 1] and 31 children of Syrian origin [group 2]) clinically compatible measles patients presenting to all healthcare institutions in Batman, Turkey, in 2023. Results: Significant differences were observed between groups in vaccination coverage (90.3% unvaccinated amongst Group 2 vs. 55.2% amongst Group 1, p < 0.001), IgM positivity (87.1% vs. 26.9%, p < 0.001) and hospitalisation rates (38.7% vs.16.4%, p = 0.015). Group 2 exhibited higher prevalence of fever (93.5% vs. 70.1%, p = 0.010) and cough (58.1% vs. 26.9%, p = 0.003) than Group 1. Conclusion: The study highlights the impact of migration and socio-economic factors on measles dynamics. Lower vaccination rates amongst Syrian migrants contribute to increased measles incidence and severity. Strengthening vaccination programmes and public health initiatives are crucial for controlling measles outbreaks and improving health outcomes, particularly in vulnerable populations.
  • Letter
    An Unexpected Presentation of Pertussis: Pneumomediastinum and Subcutaneous Emphysema
    (Wiley, 2025) Orhan, Oezhan; Ozgun, Nezir; Nayir Buyuksahin, Halime; Talay, Mehmet Nur; Gungor, Emre
  • Article
    Yararlı Bakteriler Fırsatçı Patojenlere Dönüşürse! Probiyotik Alımı Sonrası Gelişen Alkalihalobacillus clausii Sepsisi: Türkiye’den İlk Olgu Sunumu
    (2025) Özcan, Nida; Ayaydin, Zeynep; Talay, Mehmet Nur; Azarkan, Ayşe Batgi; Tekin, Ali Cem; Bilik, Özge Alkan
    Akut ishal, özellikle çocukluk çağında, potansiyel olarak zararlı sonuçları olan ciddi bir hastalıktır. Probiyotikler genellikle akut ishal tedavisinde kullanılmaktadır. Burada, Bacillus clausii (Alkalihalobacillus clausii) içeren ticari preparat kullanımı sonrası sepsis gelişen 17 yaşında serebral palsili bir kadın hasta olgusu sunulmuştur. Kan kültürlerinden izole edilen koloniler Vitek-2 otomatik sistemi ile Bacillus clausii (A. clausii) olarak tanımlanmış ve MALDI TOF-MS ile doğrulanmıştır. Probiyotik preparatından üretilen A. clausii suşunun antibiyotik duyarlılık paternine göre hastamızdan izole edilen suşla yüksek ihtimalle aynı suş olduğu kanaatine varılmıştır. Hastaya teikoplanin tedavisi uygulanmıştır. Literatür araştırmamıza göre, bilindiği kadarıyla olgumuz Türkiye’de bildirilen ilk A. clausii sepsisi olgusudur. Özellikle bağışıklık sistemi çeşitli sebeplerle zayıflamış hastalarda probiyotik preparatlar dikkatli kullanılmalıdır.