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Potentilla Fulgens Root Extract’s Effect on Breast Cancer (mcf-7) and Osteosarcoma (u2os) Cells Proliferation and Migration

dc.contributor.authorIpek, Polat
dc.contributor.authorBaran, Ayse
dc.date.accessioned2025-02-15T19:45:26Z
dc.date.available2025-02-15T19:45:26Z
dc.date.issued2024
dc.departmentArtuklu Universityen_US
dc.department-tempDİCLE ÜNİVERSİTESİ,MARDİN ARTUKLU ÜNİVERSİTESİen_US
dc.description.abstractAim: This study evaluates the cytotoxic effect of Potentilla fulgens root extract on MCF7, U2OS, and RPE-1 cell lines and investigates its impact on cell migration. Materials and Methods: The effect of Potentilla fulgens root extract on the cell viability of MCF-7, U2OS, and RPE-1 cells was analyzed using an MTT assay. The effect of the compounds on cell migration was evaluated at 24 and 48 hours using the wound healing assay. A wound-healing assay was used to measure the metastatic ability of cells in vitro. Results: MTT assay showed that PRE had a cytotoxic effect on all three cell lines, depending on dose and time, and this effect was statistically significant. The wound healing assay results showed that PRE slowed the migration of live MCF-7 and U2OS cancer cells, and these effects increased over time. Conclusion: As a result, this study indicates that PRE may be very useful in treating human osteosarcoma and breast cancer.en_US
dc.identifier.citationcount0
dc.identifier.doi10.5455/annalsmedres.2024.04.080
dc.identifier.endpage476en_US
dc.identifier.issn2636-7688
dc.identifier.issue6en_US
dc.identifier.scopusqualityN/A
dc.identifier.startpage471en_US
dc.identifier.trdizinid1243901
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2024.04.080
dc.identifier.urihttps://search.trdizin.gov.tr/en/yayin/detay/1243901/potentilla-fulgens-root-extracts-effect-on-breast-cancer-mcf-7-and-osteosarcoma-u2os-cells-proliferation-and-migration
dc.identifier.urihttps://hdl.handle.net/20.500.12514/6661
dc.identifier.volume31en_US
dc.identifier.wosqualityN/A
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiyoteknoloji Ve Uygulamalı Mikrobiyolojien_US
dc.subjectOnkolojien_US
dc.titlePotentilla Fulgens Root Extract’s Effect on Breast Cancer (mcf-7) and Osteosarcoma (u2os) Cells Proliferation and Migrationen_US
dc.typeArticleen_US
dspace.entity.typePublication

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