Potentilla Fulgens Root Extract’s Effect on Breast Cancer (mcf-7) and Osteosarcoma (u2os) Cells Proliferation and Migration

dc.contributor.author Baran, Ayşe
dc.contributor.author Baran, Ayse
dc.date.accessioned 2025-02-15T19:45:26Z
dc.date.available 2025-02-15T19:45:26Z
dc.date.issued 2024
dc.description.abstract Aim: This study evaluates the cytotoxic effect of Potentilla fulgens root extract on MCF7, U2OS, and RPE-1 cell lines and investigates its impact on cell migration. Materials and Methods: The effect of Potentilla fulgens root extract on the cell viability of MCF-7, U2OS, and RPE-1 cells was analyzed using an MTT assay. The effect of the compounds on cell migration was evaluated at 24 and 48 hours using the wound healing assay. A wound-healing assay was used to measure the metastatic ability of cells in vitro. Results: MTT assay showed that PRE had a cytotoxic effect on all three cell lines, depending on dose and time, and this effect was statistically significant. The wound healing assay results showed that PRE slowed the migration of live MCF-7 and U2OS cancer cells, and these effects increased over time. Conclusion: As a result, this study indicates that PRE may be very useful in treating human osteosarcoma and breast cancer. en_US
dc.identifier.citationcount 0
dc.identifier.doi 10.5455/annalsmedres.2024.04.080
dc.identifier.issn 2636-7688
dc.identifier.uri https://doi.org/10.5455/annalsmedres.2024.04.080
dc.identifier.uri https://search.trdizin.gov.tr/en/yayin/detay/1243901/potentilla-fulgens-root-extracts-effect-on-breast-cancer-mcf-7-and-osteosarcoma-u2os-cells-proliferation-and-migration
dc.identifier.uri https://hdl.handle.net/20.500.12514/6661
dc.language.iso en en_US
dc.relation.ispartof Annals of Medical Research en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Biyoteknoloji Ve Uygulamalı Mikrobiyoloji en_US
dc.subject Onkoloji en_US
dc.title Potentilla Fulgens Root Extract’s Effect on Breast Cancer (mcf-7) and Osteosarcoma (u2os) Cells Proliferation and Migration en_US
dc.type Article en_US
dspace.entity.type Publication
gdc.description.department Artuklu University en_US
gdc.description.departmenttemp DİCLE ÜNİVERSİTESİ,MARDİN ARTUKLU ÜNİVERSİTESİ en_US
gdc.description.endpage 476 en_US
gdc.description.issue 6 en_US
gdc.description.publicationcategory Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı en_US
gdc.description.scopusquality N/A
gdc.description.startpage 471 en_US
gdc.description.volume 31 en_US
gdc.description.wosquality N/A
gdc.identifier.trdizinid 1243901
relation.isAuthorOfPublication 3bf56afd-8586-4d9c-99d5-d5e66c4c6b15
relation.isAuthorOfPublication.latestForDiscovery 3bf56afd-8586-4d9c-99d5-d5e66c4c6b15

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