Acute Toxicity of Deltamethrin on the Fatty Acid Composition of Phospholipid Classes in Liver and Gill Tissues of Nile Tilapia

Abstract

Deltamethrin is a pyrethroid pesticide contaminating aquatic ecosystems. The purpose of this study was to clarify the acute toxicity of deltamethrin on the fatty acids of phospholipid (PL) classes in liver and gill of Nile tilapia. The fatty acids of PL classes were analyzed by gas chromatography. Deltamethrin brought about differences in the fatty acids of the PL classes in the liver and gill. In the liver of exposed fish, 16:0, 18:2(n-6), 22:6(n-3) in phosphatidylcholine (PC); 16:0, 18:1(n-9), 18:2(n-6), 20:4(n-6), 22:6(n-3) in phosphatidylethanolamine (PE); 16:0, 18:0, 18:1(n-9), 20:4(n-6), 22:6(n-3) in phosphatidylinositol (PI) and in phosphatidylserine (PS) 16:0, 18:1(n-9), 20:4(n-6), 22:6(n-3) were the affected fatty acids. There were significant alterations in ∑MUFAs (monounsaturated fatty acids), ∑(n-3)PUFAs (polyunsaturated fatty acids) and ∑(n-6)PUFAs in PC; ∑SFAs (saturated fatty acids), ∑MUFAs, ∑PUFAs, ∑(n-3)PUFAs and ∑(n-6)PUFAs in PE; ∑SFAs, ∑MUFAs, ∑(n-3)PUFAs and ∑(n-6)PUFAs in PI and ∑SFAs, ∑MUFAs, ∑PUFAs and ∑(n-3)PUFAs in PS. In the gill, 18:2(n-6), 20:4(n-6), 22:6(n-3) in PC; 16:0, 18:1(n-9), 20:4(n-6), 22:6(n-3) in PE; 16:0, 18:0, 18:1(n-9), 18:2(n-6) in PI and in PS 16:0, 18:0,18:1(n-9), 20:3(n-6), 20:5(n-3), 22:6(n-3) affected. The alterations in ∑SFAs, ∑MUFAs, ∑PUFAs and ∑(n-6)PUFAs in PC; ∑SFAs, ∑MUFAs, ∑PUFAs, ∑(n-3)PUFAs and ∑(n-6)PUFAs in PE; ∑(n-3)PUFAs and ∑(n-6)PUFAs in PI; ∑SFAs, ∑MUFAs, ∑PUFAs, ∑(n-3) PUFAs and ∑(n-6)PUFAs in PS were significant in gill. The changes in the fatty acids of the PL classes in response to deltamethrin can influence structure and functions of the membrane systems. Changes in fatty acids may be one defense mechanism against the deltamethrin. © 2017, University of Tehran.