WoS İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12514/3595

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The Transcript of a Long Story: a Critical Analysis of Eurocentric Prejudices in Turkey's European Union Membership Process
(Scientific Scholar LLC, 2025) Birkan, O.
Turkey’s European Union (EU) membership process has long been knotted in identity-based discussions that frame Turkey as an outsider, reinforcing the perception that it poses a cultural and political challenge to European unity. This study critically examines the role of Orientalist narratives in shaping the EU’s approach to Turkey’s membership, arguing that Turkey’s exclusion is not merely a result of political or economic misalignment but is deeply rooted in Eurocentric prejudices. Drawing on Edward Said’s Orientalism (1978), this paper explores how the concept of "Europeanization" extends beyond institutional alignment ("EUization") to include implicit cultural and civilizational boundaries. The study employed a qualitative, interpretative methodology to analyze the EU’s lengthy strategies and policy frameworks that construct Turkey as the "Other." It further investigates how Orientalist tropes manifest in debates surrounding Turkey’s geopolitical position, religious identity, and democratic credentials, affecting the EU’s inconsistent application of membership criteria. The findings reveal that the EU’s reluctance to integrate Turkey stems from an exclusionary European identity that prioritizes ethno-religious homogeneity over pluralism. Furthermore, mechanisms such as the “privileged partnership” model and discourse on the EU’s "absorption capacity" reflect an Orientalist mindset that seeks to control rather than integrate Turkey. By uncovering these underlying biases, this study contributes to broader discussions on European identity, integration policies, and the persistence of Orientalist thought in contemporary political discourse. © 2025 Journal of King Saud University – Science-Published by Scientific Scholar.
Effect of Carvacrol on Diabetes-Induced Oxidative Stress, Fibrosis and Apoptosis in Testicular Tissues of Adult Rats
(Acad Sciences Czech Republic, inst Physiology, 2025) Gultekin, Burcu; Cetinkaya Karabekir, Seda; Cinar Ayan, Ilknur; Savas, Hasan Basri; Cuce, Gokhan; Kalkan, Sabiha Serpil
Diabetes mellitus (DM) is a chronic and widespread disease that negatively affects the male reproductive system. Carvacrol (CAR), a naturally occurring flavonoid in plants, exhibits various biological and pharmacological activities, including antiinflammatory, antioxidant, and anticancer properties. This study aimed to investigate the potential effects of CAR on testicular tissue damage induced by diabetes, which was modeled by Streptozotocin (STZ) administration. Thirty-two male Wistar albino rats were divided into four groups: Group 1: Control (n=8), Group 2: DM (n=8), Group 3: DM+DMSO (0.1 % dimethyl sulfoxide) (n=8), and Group 4: DM+CAR (20 mg/kg) (n=8). Diabetes was induced by a single intraperitoneal STZ injection (50 mg/kg). Histological changes were assessed using Hematoxylin-Eosin (H&E) staining and the Johnsen scoring system. Apoptosis was evaluated through immunohistochemical staining for the mitochondrial apoptosis markers Bax and Bcl-2, as well as RT-qPCR analysis of their gene expression levels. Fibrosis assessment involved Masson-Trichrome staining and RT-qPCR analysis of mRNA levels for the COL1A1 and COL3A1 genes. Additionally, Total Oxidant Status (TOS), Total Antioxidant Status (TAS), Oxidative Stress Index (OSI), and C-Reactive Protein (CRP) levels were measured in testicular tissue. CAR treatment significantly improved histological alterations associated with diabetes-induced testicular damage. DM was found to increase Bax levels while reducing Bcl-2 levels, whereas CAR reduced Bax levels and increased Bcl-2 gene and protein expression. TOS and OSI levels were elevated in the DM group, whereas TAS levels increased in the DM+CAR group. No significant differences in CRP levels were observed between the groups. These findings suggest that CAR may be effective in mitigating diabetes-induced testicular damage.
High-Flow Nasal Cannula Oxygen Versus Conventional Oxygen Therapy in a Rat Model of Severe Carbon Monoxide Toxicity
(MRE Press, 2025) Cakmak, Sumeyye; Gokdemir, Gul Sahika; Gokdemir, Mehmet Tahir; Sogut, Ozgur; Erkan, Revsa Evin Canpolat
Background: This study compared the efficacy of high-flow nasal cannula (HFNC) oxygen therapy with conventional oxygen therapy (COT) using a simple face mask for clearing carbon monoxide (CO) from the bloodstream in a rat model of severe CO poisoning. Methods: Twenty-eight male Wistar rats were assigned to four groups: severe CO intoxication treated with HFNC, a sham group (no intoxication or treatment), severe CO intoxication treated with COT, and a control group with severe CO intoxication receiving no treatment. Their arterial blood gas and metabolic parameters were analyzed and compared to determine treatment effectiveness. Results: Significant differences were observed among the groups in terms of carboxyhemoglobin (COHb), pH, bicarbonate (HCO3), hemoglobin, sodium (Na), potassium (K), calcium (Ca), glucose and lactate levels. Both treatment groups had lower COHb and lactate levels compared to the untreated control group, with COHb clearance being significantly higher in the HFNC group than in the COT group (20.33% +/- 3.58% vs. 41.17% +/- 6.49%; p < 0.001). Additionally, pH levels were higher in the HFNC group than in the COT group (7.32 +/- 0.07 vs. 7.27 +/- 0.05; p = 0.486). Conclusions: HFNC oxygen therapy was found to be more effective than COT in promoting CO elimination and improving arterial blood gas parameters, indicating its potential as a superior treatment strategy for severe CO poisoning.
First Report of Fusarium Equiseti Causing Postharvest Fruit Rot of Avocado in Türkiye
(Wiley, 2025) Bozoglu, Tugba; Dervis, Sibel; Ozer, Goksel; Turkkan, Muharrem
In September 2024, postharvest fruit rot, including stem-end rot, was observed on avocado in the Alt & imath;nordu district of Ordu province, located in the Eastern Black Sea Region of T & uuml;rkiye. A market survey revealed that 5% of fruit exhibited fruit rot symptoms, a subset of which displayed stem-end rot symptoms, including brown to black lesions extending into the mesocarp, shrivelling and fungal mycelium growth. Fusarium equiseti was identified as the causal agent through morphological characterisation and molecular analysis using PCR amplification and sequencing of translation elongation factor 1-alpha (tef1) and RNA polymerase II second largest subunit (rpb2) gene sequences, including phylogenetic analysis. Artificial inoculation and subsequent re-isolation confirmed Koch's postulates, verifying F. equiseti as the causal pathogen. This is the first report of F. equiseti causing both fruit rot and stem-end rot on avocado in T & uuml;rkiye, highlighting the need for improved postharvest disease management strategies to reduce economic losses in T & uuml;rkiye's avocado industry.
Causes of Diagnostic and Treatment Delays in Locally Advanced Breast Cancer: a Nationwide Multicenter Survey and Electronic Health Records Analysis in Turkiye
(Oxford Univ Press, 2025) Karadeniz Cakmak, Guldeniz; Tali, Ufuk; Balbaloglu, Hakan; Tasdoven, Ilhan; Ozkurt, Enver; Karanlik, Hasan; Ozmen, Vahit
Delays in breast cancer (BC) diagnosis and treatment negatively impact survival outcomes. Understanding patient- and provider-related factors behind these delays is crucial. This study aimed to identify nationwide reasons for delayed diagnosis and treatment of locally advanced BC in Turkiye. A prospective, multicenter hospital-based survey was conducted across 35 institutions between 2023 and 2024. Patient- and provider-related delays were assessed via a structured 61-item face-to-face survey, supplemented by clinical data from electronic health records. Delays exceeding 3 months were clinically categorized as significant. A total of 1322 women participated from seven regions across Turkiye. Factors contributing to diagnostic delays on a national level included economic reasons (5.5%), lack of family support (3.3%), lack of knowledge (12.4%), lack of time due to household work (3.8%), difficulty in finding an appointment (6.7%), pregnancy-related reasons (1.1%), fear of losing the breast (8.9%), fear of death (9.8%), and transportation difficulties (5.1%). Provider-related delays were infrequent. About 89.3% of the patients had the initial doctor appointment and 89.6% had the first specialist consultation within one month. Treatment planning was predominantly based on a multidisciplinary team decision in 88.3% of patients. Regarding treatment initiation, 93.2% started required treatment within 1 month of decision. Patient-related factors are the major causes of diagnostic delay in Turkiye. On the other hand, from the provider's perspective, the presence of multidisciplinary teams, including dedicated breast surgeons, represents a key factor in ensuring the timely implementation of diagnostic procedures and treatment strategies.
Control Strategy Evaluation for Reactive Power Management in Grid-Connected Photovoltaic Systems Under Varying Solar Conditions
(Nature Portfolio, 2025) Adak, Suleyman
Solar energy is environmentally friendly and one of the most significant renewable energy sources. This energy is a leading renewable energy source, contributing significantly to sustainable development goals. In grid-connected photovoltaic (PV) systems, reactive power management is essential for maintaining voltage stability and ensuring reliable operation. However, the influence of fluctuating solar irradiation (G) on reactive power (Q) behavior is often underrepresented in conventional inverter control strategies. This research addresses this gap by modeling the dependence of reactive power on solar irradiance using a data-driven curve-fitting approach. The methodology involves the acquisition of real-world operational data, preprocessing, selection of an appropriate analytical model, and validation of its performance. The findings indicate that reactive power increases under low irradiance conditions, primarily due to inverter behavior and grid voltage support requirements. The resulting analytical expression offers a practical framework for integrating irradiance-dependent reactive power control into inverter firmware or grid management software. The model performed with high accuracy with an R2 of 0.9955. This contribution enhances the ability of PV systems to respond dynamically to environmental changes, improving grid compatibility, operational efficiency, and voltage regulation in modern distributed energy networks.
Isokinetic Knee Strength as a Predictor of Performance in Elite Ski Mountaineering Sprint Athletes
(MDPI, 2025) Kural, Burak; Caglar, Esin Cagla; Akkus Ucar, Mine; Ozer, Ugur; Yenturk, Burcu; Cayir, Huseyin; Ceylan, Levent
Background and Objectives: This study aims to investigate the relationship between isokinetic knee strength and competition performance in elite male ski mountaineering sprint athletes and to identify strength parameters that predict performance and contribute to injury prevention. Materials and Methods: Thirteen male athletes participating in the Ski Mountaineering Turkey Cup final stage were included. Isokinetic knee flexion (FLX) and extension (EXT) strength of dominant (DM) and non-dominant (NDM) legs were measured at angular velocities of 60 degrees/s and 180 degrees/s using the DIERS-Myolin Isometric Muscle Strength Analysis System. Competition performance was evaluated using the ISMF scoring system. Data were analyzed using SPSS 26.0 with Pearson correlation and multiple regression analyses after normality, linearity, and homoscedasticity checks. Results: Strong positive correlations were found between hamstring strength at high angular velocities (180 degrees/s) and performance (DM FLX: r = 0.809; NDM FLX: r = 0.880). Extension strength showed moderate correlations at low velocities (60 degrees/s) (DM EXT: r = 0.677; NDM EXT: r = 0.699). Regression analysis revealed that DM FLX at 180 degrees/s and DM EXT at 60 degrees/s explained 49% of performance variance (Adj. R2 = 0.498). For NDM legs, only 180 degrees/s FLX was a significant predictor (beta = 1.468). Conclusions: High-velocity hamstring strength plays a critical role in ski mountaineering sprint performance, particularly during sudden directional changes and dynamic balance. Quadriceps strength at low velocities contributes to prolonged climbing phases. Moreover, identifying and addressing bilateral strength asymmetries may support injury prevention strategies in elite ski mountaineering athletes. These findings provide scientific support for designing training programs targeting explosive hamstring strength, bilateral symmetry, and injury risk reduction, essential for optimizing performance in the 2026 Winter Olympics sprint discipline.
Determination of the Protective Effect of Curcumin Against Tartrazine-Induced DNA Damage and HSP 70 in the Rat Brain
(Springer, 2025) Yavas, Mehmet Cihan; Tan, Fazile Canturk; Tur, Kardelen; Keskin, Cumali; Basmaci, Guldidar
Tartrazine is a widely used food dye, and children often consume large amounts of food products containing this additive due to their appealing appearance. Curcumin, on the other hand, is known for its antioxidant properties. The aim of this study was to investigate the protective effects of curcumin on brain tissue and biochemical parameters in rats exposed to short-term tartrazine administration. Male Wistar albino rats were randomly divided into five equal groups. Group 1 served as the control; Group 2 received tartrazine (10 mg/kg); Group 3 received tartrazine (100 mg/kg); Group 4 received tartrazine (10 mg/kg) along with curcumin (20 mg/kg); and Group 5 received tartrazine (100 mg/kg) along with curcumin (20 mg/kg). All substances were administered via oral gavage. The study lasted for 21 days. Serum samples were analyzed for heat shock protein 70 (HSP70) levels using the ELISA method. Brain tissues were subjected to histopathological examination and DNA damage assessment using the comet assay. Although HSP70 levels increased in the tartrazine groups, the differences were not statistically significant (p = 0.065). Partial damage was observed in the histopathological analysis. Comet assay results indicated a dose-dependent increase in DNA tail percentage with tartrazine, which was reduced following curcumin administration. These findings suggest that curcumin may alleviate tartrazine-induced damage in brain tissue and may have a regulatory effect on serum HSP70 levels in rats.
Bioactive Profile, Anticarcinogenic, Antimicrobial, Antidiabetic Effects, and in Silico Pharmacokinetic Properties of Astragalus Elatus
(Academic Press inc Elsevier Science, 2025) Ercan, Leyla; Akan, Hasan; Caliskan, Cemile Gunbegi
Because of the numerous useful components they contain, plants are significant resources that are being explored for their varied purposes in industry, food, and medicine. Recently, particularly endemic species have gained attention with the identification of their different ingredients and characteristics and the exploration of their precious features. This research assessed the endemic species Astragalus elatus's bioactive components utilizing UHPLC-Orbitrap (R)-HRMS, its antibacterial qualities utilizing the disc diffusion method, its cytotoxic impact on cervical cancer utilizing the MTT method, and its apoptosis effect by annexin V methods. Additionally, Astragalus elatus's antidiabetic activity was revealed by in silico and in vitro examinations of its inhibitory effect on the enzymes alpha-Amylase and alpha-Glucosidase. Consequently, it was discovered that A. elatus can be utilized in the treatment of cervical cancer and has effective cytotoxic and apoptotic effects on HeLa cells. Additionally, it was detected that A. elatus possesses antibacterial and anti-diabetic properties. Compared to gram-negative bacteria, A. elatus had a greater inhibitory effect on gram-positive bacteria. The pharmacokinetically significant characteristics and their tendency for chemical reactions of this plant's primary phenolic compounds were identified by utilizing DFT, molecular docking, and ADME/T.
Evaluation of Transcutaneous Bilirubin Levels in Healthy and Preeclamptic Pregnancies: a Pilot Study
(BMC, 2025) Onat, Miray; Kavak, Ebru Celik; Akcabay, Cigdem; Malkan, Zubeyde; Kaya, Tugba; Batmaz, Ibrahim; Kavak, Salih Burcin
Background Preeclampsia is a complex, multisystem obstetric disorder characterized by heterogeneous clinical manifestations, often requiring enhanced strategies for early detection, management, and risk stratification. This study aimed to evaluate potential alterations in non-invasive transcutaneous bilirubin levels measured at various maternal body sites in pregnant women diagnosed with preeclampsia. Methods A total of 86 pregnant women who delivered at our institution were enrolled and classified into three groups: healthy pregnant women (Group 1, n = 30), women with preeclampsia (Group 2, n = 30), and women with pre-eclampsia with severe features (Group 3, n = 26). In addition to routine pre-delivery laboratory assessments, transcutaneous bilirubin levels were measured at two anatomical sites-the forehead and the abdominal skin overlying the uterine fundus-using a standard bilirubinometer. Each site was measured three times, and the mean of the three readings was recorded for analysis. Complete Blood Count and biochemical blood parameters of the women were evaluated. Relevant obstetric and demographic data were also collected and recorded. Results There were no statistically significant differences among the three groups in terms of maternal age, gravidity, parity, or body mass index (p > 0.05). Similarly, total serum bilirubin levels were comparable across the groups (Group 1: 0.45 mg/dL; Group 2: 0.39 mg/dL; Group 3: 0.44 mg/dL; p > 0.05). In contrast, transcutaneous bilirubin levels were significantly elevated in Group 3 compared to Groups 1 and 2. The mean transcutaneous bilirubin values for the forehead, uterine fundus, and overall (combined sites) were as follows: Group 1-3.07 +/- 0.85, 2.35 +/- 0.97, and 2.71 +/- 0.76; Group 2-6.09 +/- 1.94, 4.94 +/- 1.64, and 5.52 +/- 1.59; Group 3-7.12 +/- 1.81, 6.12 +/- 2.25, and 6.63 +/- 1.69, respectively. All pairwise comparisons demonstrated statistically significant differences (p < 0.05). Conclusions Transcutaneous bilirubin levels were significantly elevated in women with preeclampsia, particularly among those with severe disease. As a non-invasive, rapid, and cost-effective approach, TcB measurement may function as an adjunctive tool for the initial clinical assessment and risk stratification of preeclamptic patients.
Prognostic Value of Hemoglobin, Albumin, Lymphocyte, Platelet (HALP) Scores in Patients With Non-Valvular Atrial Fibrillation: Insights From the After-2 Study
(BMC, 2025) Soner, Serdar; Guzel, Tuncay; Aktan, Adem; Kilic, Raif; Soner, Hulya Tosun; Demir, Muhammed; Ertas, Faruk
Objectives: The relationship between hemoglobin, albumin, lymphocyte, platelet (HALP) score, and various cancers and cardiovascular diseases has been tested previously. However, the relationship between HALP score and non-valvular atrial fibrillation (NVAF) has not been adequately tested. Therefore, our study aimed to investigate the relationship between HALP score and mortality in patients with NVAF. Methods: This study included 2,592 NVAF patients from 35 centers in Turkey. Patients were divided into two groups: those with HALP scores <= 58.96 (low HALP score group, 1,296 patients) and > 58.96 (high HALP score group, 1,296 patients). The primary outcome measured was all-cause mortality. Results: The mean HALP score was 66 +/- 33. Patients in the low HALP score group had higher 1- and 5-year all-cause mortality rates (1-year: 12.9% vs. 5.4%, p < 0.001; 5-year: 38.5% vs. 20.2%, p < 0.001). Cox regression analysis identified the HALP score as an independent predictor of mortality (1-year: HR = 0.987, 95% CI = 0.981-0.992, p < 0.001; 5-year: HR = 0.990, 95% CI = 0.987-0.993, p < 0.001). ROC analysis determined a HALP score 52.3 predicted 1-year mortality with 62.9% sensitivity and 62% specificity (AUC = 0.680); a score of 55 predicted 5-year mortality with 60.3% sensitivity and 62.2% specificity (AUC = 0.657). Kaplan-Meier analysis revealed increasing mortality over time in the low HALP score group (log-rank tests, 1-year = 44.86, p < 0.001; 5-year = 108.54, p < 0.001). Conclusions: The HALP score is a simple, accessible measure, and our findings suggest that lower HALP scores are associated with increased 1-year and 5-year mortality in NVAF patients. This provides a reference for clinicians assessing risk in this vulnerable population.
The Economics of Service Robots in Hospitality Companies
(Sage Publications Ltd, 2025) Ivanov, Stanislav; Seyitoglu, Faruk; Webster, Craig
The paper develops a conceptual framework for the economic aspects of service robots in hospitality companies that includes several key components: task automatability by service robots; effects of service robots on back-of-house and front-of-house operations (full vs partial process automation); impacts of service robots on jobs in hospitality companies (substitution, enhancement/augmentation, transformation, new job creation); and the effects of service robots on key performance metrics such as productivity, profitability, revenue, and cost. Additionally, the paper looks at the external and internal factors that drive the economic aspects of service robots in hospitality. Finally, the paper outlines the theoretical and managerial implications and develops a research agenda on the economics of service robots.
Integration of the Provus Discrepancy Model in Assessing Spatial Flexibility in Architectural Design Studios
(Routledge Journals, Taylor & Francis Ltd, 2025) Bekar, Irem; Kutlu, Izzettin
Architectural education studios are significant spaces for assessing spatial use by students and faculty. This study aimed to evaluate user satisfaction in architecture faculty studios using the Provus Discrepancy Model. The findings revealed that while students expressed higher satisfaction, faculty members tended to be more critical in their evaluation of the spaces. This situation indicates that the needs and perceptions of different user groups may vary in the design of educational environments. The results underscore the importance of accommodating diverse user requirements in studio configuration, rather than adopting a one-size-fits-all approach. The study provides empirical evidence to inform the enhancement of flexibility in architectural education studios, contributing to the development of spaces better aligned with evolving pedagogical and practical needs.
ModelS4Apnea: Leveraging Structured State Space Models for Efficient Sleep Apnea Detection From ECG Signals
(IOP Publishing Ltd, 2025) Zan, Hasan
Objective. Sleep apnea is a common sleep disorder associated with severe health risks, necessitating accurate and efficient detection methods. Approach. This study proposes ModelS4Apnea, a deep learning framework for sleep apnea detection from electrocardiogram (ECG) spectrograms, integrating structured state space models (S4) for temporal modeling. The framework consists of a convolutional neural network module for local feature extraction, an S4 module for capturing long-range dependencies, and a classification module for final predictions. Main results. The model was trained and evaluated on the Apnea-ECG dataset, achieving an accuracy of 0.933, an F1-score of 0.912, a sensitivity of 0.916, and a specificity of 0.944, outperforming most prior studies while maintaining computational efficiency. Significance. Compared to existing methods, ModelS4Apnea provides high classification performance with significantly fewer trainable parameters than long short-term memory-based models, reducing training time and memory consumption. The model's ability to aggregate segment-level predictions enabled perfect per-recording classification, demonstrating its robustness in diagnosing sleep apnea across entire recordings. Moreover, its low memory footprint and fast inference speed make it well-suited for wearable devices, home-based monitoring, and clinical applications, offering a scalable and efficient solution for automated sleep apnea detection. Future work may explore multi-modal data integration, real-world deployment, and further optimizations to enhance its clinical applicability and reliability.
Transandantal Ego Egoizme Karşı: Jesse Prinz’in Empati Yorumuna Fenomenolojik Bir İtiraz
(Beytulhikme Felsefe Cevresi, 2025) Dalar, Ibrahim
This article will first reconstruct how Husserl's exploration of the transcendental intersubjectivity, starting with transcendental ego, effectively resolves the enigma of solipsism. It will also establish that transcendental ego, as uncovered by Husserl through Cartesian way, does not embody the self-contained solipsism of a Cartesian ego. Secondly, we will give an examination of transcendental intersubjectivity, which is grounded and deepened through Husserl's theory of empathy. While Husserl did not specifically formulate a phenomenology of ethics centred on empathy, his analyses on the concept of empathy hold great promise. As Husserl's transcendental intersubjectivity analyses progress via empathy, empathy will soundly proceed through a non-egoistic framework, and it may motivate moral action. Finally, the transcendental foundations of empathy will be used to refute Jesse Prinz's claims that empathy is unnecessary for moral judgement and interferes with it. Our answer will highlight the complexity and variability of empathic responses, and this will imply that empathy can indeed motivate moral actions and moral judgements.
Synthesis and Characterization of Fe3O4/MethylCellulose@Pb as a Heterogeneous Fenton-Like Catalyst for Photodegradation of Different Dyes
(Elsevier, 2025) Umaz, Adil; Ece, Mehmet Sakir
With the development of industry, serious pollution has emerged in water resources. This poses serious problems for the health of living things and the environment. To deliver a sustainable future, producing effective, low-cost, and reusable photocatalysts in wastewater treatment is important. In this study, Fe3O4/MetCel@Pb photo-catalysts were synthesized for the first time. The properties of Fe3O4/MetCel@Pb photocatalysts were characterized by Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Brunauer-Emmett-Teller (BET), Ultraviolet-Visible Spectrophotometry (UV-Vis), Vibrating Sample Magnetometry (VSM), Electron Spin Resonance (ESR), Scanning Electron Microscopy (SEM), Transmission Electron Microscope (TEM), and X-ray Photoelectron Spectroscopy (XPS). The average particle size, surface area, band gap energy, saturation magnetization, resonance magnetic field, and g-factor values of the Fe3O4/MetCel@Pb photocatalysts measured as 63.88 nm, 40.59 m2 g-1, 5.71 eV, 24.80 emu g-1, 390.15 mT, and 1.731, respectively. XPS analysis showed signals confirming strong C-O bonds, Fe-O bonds, Fe2+, and Fe3+ at binding energies of 286.04, 528.00, 711.39, and 723.84 eV, respectively. Also, Fe3O4/MetCel@Pb photocatalysts were used for the first time in the dye degradation. The degradation of methylene blue (MB), methyl orange (MO), phenol red (PR), alizarin yellow (AY), and bromthymol blue (BTB) dyes under ultraviolet-visible light for 30 min was determined as 100 %, 96.76 %, 94.51 %, 80.81 %, and 71.93 %, respectively. In the reusability study, Fe3O4/MetCel@Pb photo-catalysts showed a reduction rate of 1.70 % compared to the first cycle even after the fourth cycle. The stability and repeated reusability of Fe3O4/MetCel@Pb photocatalysts without deformation were realized. Application of Fe3O4/MetCel@Pb photocatalysts in real dyed water samples (even in mixed matrix samples) showed over 90 % dye degradation efficiency. This confirms that the photocatalyst is an effective catalyst in dye degradation. Fe3O4/MetCel@Pb photocatalysts, which are economical, easy to prepare, and stable, will be an effective option for the removal of industrial waste paints (cationic and anionic dye) from aqueous systems. In addition, using these photocatalysts will provide ease of process, as well as time and cost savings.
Citation - Scopus: 3
An Effort To Understand Parents' Media Mediation Roles and Early Childhood Children’s Digital Game Addiction Tendency: a Descriptive Correlational Survey Study
(Springer, 2024) Calhan, Ceren; Goksu, Idris
This study aims to determine whether parents' media mediation roles are related to their early childhood children's digital game addiction tendencies. In addition, it examines whether these variables are related to the child's and parent's digital device usage habits and whether they differ according to various sociodemographic variables and digital device usage habits. In this context, we collected data from 433 parents (mother = 336, father = 97) with children aged 3-6. We analyzed the data using correlation analysis, one-way ANOVA, and t-test. Active-supportive, restrictive-supportive, active-limiting, restrictive-limiting, and active-interpreter roles of parents were negatively related to children's digital game addiction tendencies. In addition, parents' and children's digital device screen time was negatively associated with parents' media mediation roles and positively with children's digital game addiction tendencies. Mothers found their children more likely to have digital game addiction than fathers. Children of parents who play digital games have higher digital game addiction than those of parents who do not play, male children than female, children who have their own digital devices than those who do not, and children who only watch YouTube videos than those who only watch television channels for kids. Finally, we observed that mothers are more active in media mediation roles than fathers and that parents behave more restrictive toward their daughters.
Effects of Trimetazidine on Oxidant-Antioxidant Balance and Angiogenesis; an in Vivo Experimental Study
(BMC, 2025) Kayan, Fethullah; Savas, Hasan Basri
Background We evaluated the effects of trimetazidine (TMZ) on the oxidative-antioxidative balance and angiogenesis in an in vivo experimental model. This study aims to evaluate the effects of trimetazidine on angiogenesis through histological analysis and to assess its impact on oxidative-antioxidative balance through biochemical measurements. Methods In this study, Ross 308 breed chicken eggs (n = 40) were used, and embryos were divided into four distinct groups. On the eighth day of incubation, the vascular density of the embryos was examined. Following the assessment of vascular development, 4-5 mL of albumin was collected via syringe to measure oxidative stress markers. Each group consisted of 10 embryos, with a total of 40 embryos used in the study. The groups were organized as follows: Control Group (CG), Bevacizumab Group (BC), Trimetazidine 10(-)(4) Group, and Trimetazidine 10(-)(5) Group. Results When the total oxidative capacity (TOC) levels were compared among the groups, the bevacizumab group exhibited significantly higher values than the control group (p < 0.05). In oxidative stress index (OSI) measurements, the bevacizumab group also showed significantly higher values compared to the control group (p < 0.05). In contrast, when the total antioxidant capacity (TAC) levels were compared, both the Trimetazidine 10(-)(4) and Trimetazidine 10(-)(5) groups demonstrated significantly higher values than the control group (p < 0.05). Regarding angiogenesis scoring, the bevacizumab group exhibited a significant anti-angiogenic effect compared to the control group. However, no statistically significant difference was observed between the Trimetazidine 10(-)(4) and Trimetazidine 10(-)(5) groups and the control group (p > 0.05). Conclusion Trimetazidine demonstrated significant antioxidant activity in an in vivo Chorioallantoic Membrane (CAM) model at both 10(-)(4) M and 10(-)(5) M concentrations. However, no positive or negative effects on angiogenesis were detected. We believe that the real-time observation of angiogenesis in our study provided significant value to our research.
2023-2024 Excavations at Boğaziye Höyüğü: a Recently Discovered Mound Settlement in the Upper Khabur Region
(Istanbul Univ, 2025) Gene, Bulent; Sahin, Muaviye; Isik, Senem; Abakay, Ayda; Kaya, Semsihan; Konyar, Erkan; Tan, Armagan
Boğaziye Höyük lies at the northwestern end of the vast and fertile Upper Khabur Region, which stretches along the southern foothills of the Kašiari Mountains. Material culture remains unearthed at the mound by two seasons of excavations (2023-2024) shows significant similarities to assemblages known from other Upper Khabur sites. Our excavations in Trenches BE18-BE17 and BF18 on the northern slope of the mound focused on revealing the stratigraphic sequence in this area. Architectural remains of Building Levels I and II and finds from these contexts in Trench BE18 are dateable to the mid-3rd millennium BC. In Trench BE17, Building Level I also revealed finds that can be dated to the 3rd (especially mid-3rd) millennium BC, and in Trench BF18, ceramic sherds dateable to the 3rd millennium BC were found in Building Level III. This article presents new findings from Boğaziye Höyük and discusses their significance in comparison with the results of surveys and excavations in the Upper Khabur Region, which have continued increasingly since the mid-1930s. We evaluate the significance of Boğaziye Höyük as a regional center within the Upper Khabur basin, and we elucidate its habitation sequence and building levels in the light of our recent excavations. Based on a comparative evaluation of its material culture remains within a regional perspective, we contextualize Boğaziye Höyük in relationship to the cultural horizons of the early and mid-3rd millennium BC in the Upper Khabur Valley.
The Architecture and Village-Spatial Organization of the Middle PPNB Period at Boncuklu Tarla: Some Observations on the Domestic and Public Areas
(Istanbul Univ, 2025) Kodak, Ergul; Ciftci, Yunus; Kodak, Charlotte Labedan; Cin, Rustem
Boncuklu Tarla is a settlement located within the borders of the village of Il & imath;su in the Darge & ccedil;it district of Mardin. The settlement provides important information on the architecture ofthe PPNA and PPNB periods, in particularthe architectural traditions ofthe Middle PPNB, the focus ofthis article. In addition, these remain to allow the evaluation of village-space organization. The architectural remains found at Boncuklu Tarla also provide the opportunity to compare the Middle PPNB period architecture unearthed atvarious settlements such as & Ccedil;ay & ouml;n & uuml;, Nevali & Ccedil;ori, Gritille, Tell Halula, Akar & ccedil;ay Tepe, Gre F & imath;lla and Cafer H & ouml;y & uuml;k in a regional context. This study aims to present and discuss new information on how village spatial organization changed within the PPNB period, following on from previous discussions on the PPNA period data. Especially within the Middle PPNB period, it is thought that the village spatial organization model of being centered around public buildings was abandoned at Boncuklu Tarla. It is believed that with this change the public buildings were separated from the dwellings but still influenced their spatial organization.

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