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Evaluation of Hematological Parameters After Transcatheter Aortic Valve Replacement

dc.authorid0000-0001-6985-6112
dc.authorwosidHCH-3800-2022
dc.contributor.authorKarahan, Mehmet Zülkif
dc.contributor.authorAktan, Adem
dc.contributor.authorGüzel, Tuncay
dc.contributor.authorKılıç, Raif
dc.contributor.authorGünlü, Serhat
dc.contributor.authorDemir, Muhammed
dc.contributor.authorErtaş, Faruk
dc.date.accessioned2023-12-11T11:44:59Z
dc.date.available2023-12-11T11:44:59Z
dc.date.issued2023
dc.departmentMAÜ, Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.description.abstractAlthough transcatheter aortic valve replacement (TAVR) is safe and effective, mortality and bleeding events post procedure are important. The present study investigated the changes in hematologic parameters to evaluate whether they predict mortality or major bleeding. We enrolled 248 consecutive patients (44.8% male; mean age 79.0 ± 6.4 years) undergoing TAVR. In addition to demographic and clinical examination, blood parameters were recorded before TAVR, at discharge, 1 month and 1 year. Hemoglobin levels before TAVR 12.1 ± 1.8 g/dL, 10.8 ± 1.7 g/dL at discharge, 11.7 ± 1.7 g/dL at first month, 11.8 ± 1.4 g/dL at first year (Hemoglobin values compared with pre-TAVR, P < .001, P = .019, P = .047, respectively). Mean platelet volume (MPV) before TAVR 8.72 ± 1.71 fL, 8.16 ± 1.46 fL at discharge, 8.09 ± 1.44 fL at first month, 7.94 ± 1.18 fL at first year (MPV values compared with pre-TAVR, P < .001, P < .001, P < .001, respectively). Other hematologic parameters were also evaluated. Hemoglobin, platelet count, MPV, and red cell distribution width before the procedure, at discharge, and at the first year did not predict mortality and major bleeding in receiver operating characteristic analysis. After multivariate Cox regression analysis, hematologic parameters were not independent predictors of in-hospital mortality, major bleeding, and death at 1 year after TAVR.en_US
dc.description.provenanceSubmitted by Serhat Günlü (serhatgunlu@artuklu.edu.tr) on 2023-12-11T11:44:59Z No. of bitstreams: 1 2d9bcd8f0a4257312cb68a4d6b36f332b7456348631e810778b2bf4f710d8b67.pdf: 733042 bytes, checksum: 7a28739300f09137dd39123870e0d192 (MD5)en
dc.description.provenanceMade available in DSpace on 2023-12-11T11:44:59Z (GMT). No. of bitstreams: 1 2d9bcd8f0a4257312cb68a4d6b36f332b7456348631e810778b2bf4f710d8b67.pdf: 733042 bytes, checksum: 7a28739300f09137dd39123870e0d192 (MD5) Previous issue date: 2023en
dc.identifier.doi10.1177/00033197231177397
dc.identifier.urihttps://hdl.handle.net/20.500.12514/4535
dc.identifier.wosWOS:001002856000001
dc.identifier.wosqualityQ2
dc.institutionauthorGünlü, Serhat
dc.language.isoenen_US
dc.publisherSAGEen_US
dc.relation.ispartofANGIOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectaortic stenosis, hematologic parameters, transcatheter aortic valve implantation, mean platelet volume, red cell distribution width, hemoglobinen_US
dc.titleEvaluation of Hematological Parameters After Transcatheter Aortic Valve Replacementen_US
dc.typeArticleen_US
dspace.entity.typePublication

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