Evaluation of Hematological Parameters After Transcatheter Aortic Valve Replacement

dc.contributor.author Günlü, Serhat
dc.contributor.author Karahan, Mehmet Zülkif
dc.contributor.author Aktan, Adem
dc.contributor.author Kılıç, Raif
dc.contributor.author Günlü, Serhat
dc.contributor.author Demir, Muhammed
dc.contributor.author Ertaş, Faruk
dc.contributor.other Department of Internal Medical Sciences / Dahili Tıp Bilimleri Bölümü
dc.contributor.other 10. Faculty of Medicine / Tıp Fakültesi
dc.contributor.other 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
dc.date.accessioned 2023-12-11T11:44:59Z
dc.date.available 2023-12-11T11:44:59Z
dc.date.issued 2023
dc.description.abstract Although transcatheter aortic valve replacement (TAVR) is safe and effective, mortality and bleeding events post procedure are important. The present study investigated the changes in hematologic parameters to evaluate whether they predict mortality or major bleeding. We enrolled 248 consecutive patients (44.8% male; mean age 79.0 ± 6.4 years) undergoing TAVR. In addition to demographic and clinical examination, blood parameters were recorded before TAVR, at discharge, 1 month and 1 year. Hemoglobin levels before TAVR 12.1 ± 1.8 g/dL, 10.8 ± 1.7 g/dL at discharge, 11.7 ± 1.7 g/dL at first month, 11.8 ± 1.4 g/dL at first year (Hemoglobin values compared with pre-TAVR, P < .001, P = .019, P = .047, respectively). Mean platelet volume (MPV) before TAVR 8.72 ± 1.71 fL, 8.16 ± 1.46 fL at discharge, 8.09 ± 1.44 fL at first month, 7.94 ± 1.18 fL at first year (MPV values compared with pre-TAVR, P < .001, P < .001, P < .001, respectively). Other hematologic parameters were also evaluated. Hemoglobin, platelet count, MPV, and red cell distribution width before the procedure, at discharge, and at the first year did not predict mortality and major bleeding in receiver operating characteristic analysis. After multivariate Cox regression analysis, hematologic parameters were not independent predictors of in-hospital mortality, major bleeding, and death at 1 year after TAVR. en_US
dc.identifier.doi 10.1177/00033197231177397
dc.identifier.uri https://hdl.handle.net/20.500.12514/4535
dc.language.iso en en_US
dc.publisher SAGE en_US
dc.relation.ispartof ANGIOLOGY en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject aortic stenosis, hematologic parameters, transcatheter aortic valve implantation, mean platelet volume, red cell distribution width, hemoglobin en_US
dc.title Evaluation of Hematological Parameters After Transcatheter Aortic Valve Replacement en_US
dc.type Article en_US
dspace.entity.type Publication
gdc.author.id 0000-0001-6985-6112
gdc.author.institutional Günlü, Serhat
gdc.author.wosid HCH-3800-2022
gdc.description.department MAÜ, Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı en_US
gdc.description.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
gdc.description.wosquality Q2
gdc.identifier.wos WOS:001002856000001
gdc.wos.citedcount 2
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