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Citation - WoS: 23
Citation - Scopus: 25
1-(2-Hydroxyethyl)-2-imidazolidinone as corrosion inhibitor of mild steel in 0.5 M HCl solution: thermodynamic, electrochemical and theoretical studies
(Journal of Adhesion Science and Technology, 2019) Keleşoğlu, Ayşen; Yıldız, Reşit; Dehri, İlyas; 09.03. Department of Nutrition and Dietetics/ Beslenme ve Diyetetik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
The inhibition effect of 1-(2-Hydroxyethyl)-2-imidazolidinone (2-HEI) on mild steel (MS) corrosion in 0.5M HCl solution was investigated at different inhibitor concentration and temperature by electrochemical experiments, such as linear polarization resistance (LPR), electrochemical impedance spectroscopy (EIS), potentiodynamic polarization and quantum chemical calculations. The inhibitor adsorption process on mild steel in 0.5M HCl system was studied at different temperatures (20 C–50 C). Furthermore, the surface morphology of MS was also investigated with SEM in the absence and the presence of inhibitor. The adsorption of 1-(2-Hydroxyethyl)-2-imidazolidinone on MS surface is an exothermic process and this process obeys the Langmuir adsorption isotherm. The Quantum chemical findings are good agreed with the empirical data.
16. Asır Kudüs’ünde Bir İlim Kurumu Taziyye: Medresesi
(Hitit Üniversitesi, 2022) Evsen Aydın, Esra; 05.03. Department of Islamic History and Arts / İslam Tarihi ve Sanatları Bölümü; 05. Faculty of Islamic Sciences / İslami İlimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Üç semavi din için kutsal kabul edilen, bu nedenle tarih boyunca bu üç dine mensup devletlerin şehre hâkim olma mücadeleleri verdiği, yeryüzünde bu özellikte tek şehir olan Kudüs Müslümanlar için de tarihleri boyunca önemli bir konumda olmuştur. İslam idaresinde olduğu her dönemde Mekke ve Medine’den sonra üçüncü harem kabul edilen, tamamı Mescid-i Aksa olarak anılan Harem-i Şerif alanı başta olmak üzere şehrin her köşesinde Müslüman bir kimlik oluşturmak amacıyla imar ve inşa faaliyetleri devam etmiştir. Coğrafi konumu sebebiyle ticaret merkezi özelliği taşımayan, Haçlı seferlerinin olduğu dönem dışında askeri ve siyasi olarak da merkezi bir konumu olmayan Kudüs, Müslümanların hâkim olduğu zamanlarda mukaddes bir dini merkez olmanın yanında önemli bir ilim merkezi özelliği de taşımıştır. Şehirde inşa edilen medreseler, tekke ve zaviyeler, ribâtlar, hankahlar gibi müstakil dini ve ilmi kurumların yanı sıra Mescid-i Aksa’nın kendisi de sadece ibadet için kullanılan bir mescit olmayıp her zaman cami dersleri, zikir meclisleri, mestabe denilen ve avlusunda kurulan ilim halkalarıyla canlı bir ilim merkezi fonksiyonu icra etmiştir. Şehirde ilim kurumlarının tesisi Eyyûbîler döneminde başlayarak Memlükler ile zirveye ulaşmış, Osmanlılar döneminde ise daha çok mevcut sistemin, kurumların ve bu kurumları ayakta tutan vakıfların muhafazasını sağlayan bir siyaset takip edilmiştir. Osmanlı idaresine geçtikten sonra Kudüs’te bulunan medreselerin işleyişini nasıl devam ettirdiği, vakıf müessesesinin kontrolü gibi konuların anlaşılması için Kudüs medreseleri üzerine yapılacak müstakil çalışmaların sayısının artması önemlidir. Bu alanda literatüre katkı sağlamayı amaçlayan bu makalenin konusu; önemli askeri ve idari hizmetlerde bulunan, ancak ömrünün son demlerinde yaşadığı siyasi sorunların ardından bir tür emeklilik ihsanı olarak Kudüs’te yaşama talebi kabul edilen Memlük emiri Emir Tâz tarafından inşa ettirilen, orta büyüklükte olduğunu düşündüğümüz Tâziyye Medresesi’dir. Mescid-i Aksa çevresinde kurulan ve sayıları elliyi aşan medreseden biri olan Tâziyye, XVI. asırda nüfusu ancak 5 bin civarında olan şehirdeki canlı ilim hayatının bir şahidi olarak Osmanlı devletinin hâkimiyeti döneminde de faaliyetine devam etmiştir. Osmanlı döneminde Arap coğrafyasında bulunan medreselerin yapısını ve işleyişini ele alan literatürde mevcut çalışmalar daha çok vakfiyesi bugüne gelen veya mansıp sahiplerinin ve talebelerinin izinin tabakât kitaplarından sürülebildiği yani hakkında malumata ulaşmanın nispeten kolay olduğu daha büyük ölçekli ve görünürlüğü olan yapılara odaklanmaktadır. Bu makalenin amacı ise, XVI. asırda Kudüs’ün ilmi kurumlarını ve yapısını anlayabilmek için büyük ve görünür bir örneğin değil, şehirde sayıca daha fazla olan ancak hakkında sınırlı miktarda malumata rastlanan orta ölçekli bir örneğin izini sürerek literatüre kazandırmaktır. Bunun için XVI. asırda farklı tarihlere ait Şer̒iyye sicilleri ve mühimme kayıtları ile literatürde mevcut çalışmalara müracaat edilecektir. Kudüs Şer̒iyye sicilleri Arapça olup defterlerin fiziki şartları ve yazı karakterleri sebebiyle okunması konusunda zorluklarla karşılaşıldığı için Türkçe literatürde, merkezine doğrudan bu yerel kaynakları alarak konuyu inceleyen çalışma sayısının az olması nedeniyle bu makale bu yönüyle de alana katkı sağlamayı amaçlamaktadır. Makale beş başlıktan oluşmaktadır. İlk başlıkta medresenin vâkıfı olan Memlük emiri Emir Tâz hakkında biyografik bilgilere, ikinci başlıkta medresenin mekânsal özelliklerine yer verilmiştir. Medresenin devamlılığı için en önemli unsur olan vakıf gelirlerinin ve bu işleyişte görevli kişilerin ele alındığı üçüncü başlıkta hem medresenin maddi desteğinin büyüklüğü incelenmiş hem işleyişte karşılaşılan bazı sorunlar ortaya konmuştur. Dördüncü başlıkta medresenin tedris faaliyetinin unsurlarına odaklanarak Kudüs medreselerinde mansıpların tevcihi, mansıp elde etmek için rekabet, medresenin tedris kapasitesi ve sunduğu imkânlar gibi konulara Tâziyye Medresesi özelinde yer verilmiştir. Beşinci başlıkta ise medresedeki diğer dini hizmetler incelenmiştir. Vakfiyesi bugüne ulaşmayan medresenin vakıf şartlarının detaylarına ve tarih boyunca değişime uğrayıp uğramadığı bilgisine ulaşmak henüz mümkün olmadığı gibi mevcut malumat tedrisin mahiyetine ve okutulan eserlerin hangileri olduğuna dair de detaylı bilgi elde etme imkânı sunmamaktadır. Kudüs ile alakalı medreseler ve daha büyük çerçevede ilmi hayat ile alakalı çalışmaların sayısı arttıkça literatürde bulunan bu boşlukların da doldurulması mümkün olacaktır.
3D Biomechanical Analysis of Targeted and Non-Targeted Drag Flick Shooting Technique in Field Hockey and Training Strategies
(ICLEL CONFERENCES, 2017) Eskiyecek, Canan Gülbin; Meriç Bingül, Bergün; Bulgan, Çiğdem; Aydın, Menşure; 13.02. Department of Coached Education / Antrenörlük Eğitimi Bölümü; 13. School of Physical Education and Sports / Beden Eğitimi ve Spor Yüksekokulu; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
This study compared targeted and non-targeted drag flick field hockey shooting techniques in the penalty corner area, using a three-dimensional kinematic analysis. Eleven male field hockey players (mean age 19,82 +/- 1,40 years) participated voluntarily. Seven high-speed cameras (Oqus 7+) with 120Hz refresh rates were used. Field calibration was completed via the wand method. The data was evaluated in two phases: starting and fmishing. Players undertook three drag flick shots to the box using targeted and non-targeted techniques. The angular kinematics and stroke force applied to the stick were analyzed using the Qualisys Track Manager Program V2.12, and ball velocity statistics were gathered with the SPSS 18.0 program. To make an accurate target shot the players attempted to maximize their targeted shooting rates, particularly by decreasing the speed of their lower extremities.
Citation - WoS: 3
Citation - Scopus: 5
7-15 years of age group children' hypertension and obesity
(2013) Battaloğlu İnanç, Betül; 09.01. Department of Nursing / Hemşirelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Amaç: Mardin ili, ilköğretim okullarındaki öğrencilerde, hipertansiyon ve obezite değerlendirilmesi amaçlandı. Gereç ve Yöntem: Tanımlayıcı tipteki bu çalışma, Mardin ilinin, farklı sosyoekonomik düzeyindeki, üç ilköğretim okulunda, 3460 öğrenciyle yürütüldü. Öğrencilerin, obeziteleri Dünya Sağlık Örgütü’ne (WHO), kan basınçları Amerikan Pediatri Akademisi’nin yayınladığı standartlara göre tanımlandı. Çalışmanın verileri SPSS paket programında, ki-kare testi ile değerlendirildi. İstatistiksel anlamlılık p <0.05 olarak belirlendi. Bulgular: Fazla ağırlığı olan çocuk % 15.78, obez olan çocuk oranı % 10.57’ dir. Obezite sıklığı kız çocuklar için % 9.05 ve erkek çocuklar için % 11.97’ dir ( p<0.01). Öğrencilerin % 1.30’ unda presistolik hipertansiyon, % 2.02’ sinde sistolik hipertansiyon, % 2.65’ inde prediyastolik hipertansiyon ve % 2.74’ ünde diyastolik hipertansiyon görüldü. Ailesinde hipertansiyon olanlar ve onların çocukları arasında hipertansiyon ilişkisi yoktu. İki saatin üzerinde televizyon seyreden çocuklarda, obezite mevcuttu ( p=0.03). Sonuç: Okul sağlığı açısından, hipertansiyon ve obezite değerlendirmeleri gereklidir. Bu nedenle okul çağı çocuklarının muayenelerinde, bu konu mutlaka yer almalı, hipertansiyon ve obezite konusunda öğrencilere ve ailelerine eğitimler verilmelidir.
A Comparison of Native and Syrian Immigrant Women Students' Genital Hygiene Behaviors: A Cross-Sectional Study
(Univ Sao Paolo, 2025) Icke, Sibel; Cifci, Sema
Objective: This study aims to compare the genital hygiene behaviors of native and Syrian immigrant women students. Method: This was cross-sectional research. The sample size of the study was determined via power analysis and G*Power software. A total sample size of 330 individuals was equally distributed to both groups. Sociodemographic Characteristics Questionnaire" and the 'Genital Hygiene Behaviors Scale' were used as data collection tools. Results: There was a significant difference between the mean scores of the scales of both student groups (p < 0.05). The mean scores of native students were found to be higher. The variables "how to clean the genital area", "material used for genital hygiene", "washing method of underwear", "pretoilet hand washing habits" and "regular menstruation" were found to be most effective in terms of the mean scores of the Genital Hygiene Behaviors Scale and its subscales for immigrant students. Conclusion: Social security status and nationality were the most influential sociodemographic factors affecting genital hygiene behaviors. It would be beneficial to raise awareness and promote behavioral changes regarding genital hygiene through seminars, conferences, workshops, and similar events targeting all women university students.
Abnormal Uterine Bleeding in Adolescent Girls Retrospective Study
(Brieflands, 2025) Ozalkak, Servan; Yildirim, Ruken; Karakaya, Amine Aktar; Tas, Funda Feryal; Oncel, Kahraman; Okur, Nurettin; Ozbek, Mehmet Nuri
Background: Abnormal uterine bleeding (AUB) is the most common reason for gynecology-related hospital admissions in adolescence. Objectives: The present single-center study aimed to evaluate the diagnosis distribution in adolescents with AUB and to compare the clinical features and treatments of patients with hemoglobin levels below and above 10 g/dL. Methods: The present single-center study retrospectively collected demographic and epidemiological data from adolescents aged 10 - 18 years presenting to our institution with a diagnosis of AUB. Patient data were extracted from electronic medical records and analyzed using SPSS software. Descriptive statistics, including frequency, percentage, mean, standard deviation (SD), median, and interquartile range (IQR), were calculated. Patients were classified according to hemoglobin levels (< 10 g/dL as group 1 and >= 10 g/dL as group 2). Results: Among 167 adolescent patients, 35.9% had hemoglobin levels below 10 g/dL. Hospitalization rates were significantly higher in group 1 (86.4%) compared to group 2 (2.8%) (P < 0.001). The most common causes of AUB were anovulation (84.4%) and polycystic ovary syndrome (PCOS) (11.4%). The primary treatments included combined oral contraceptives (COCs) with iron supplementation (45.5%) and iron alone (28.7%). Erythrocyte transfusion (ERT) was performed in 18% of cases, predominantly in group 1. This study is limited by the lack of a standardized quality of life assessment tool for AUB. The single-center design and retrospective data collection may limit the generalizability of the findings and introduce selection bias, respectively. Conclusions: Anovulation and PCOS are the main causes of AUB in adolescents. Patients with hemoglobin levels below 10 g/dL and active bleeding should be evaluated carefully, as ERT may be necessary. A wide differential diagnosis should always be considered when managing adolescent AUB.
Abu Ubayd’s Understanding Of Naskh;
(Hitit Univ, 2022) Yasar, Mehmet Aziz; Nas, Taha
In the period when Islamic sciences were formed, a large number ofscholars with absolute ijtihad capacity were trained. One of the scholars mentioned is Abu `Ubayd al- Qasim ibn Sallam al-Khurasani al-Harawi who was educated by many famous scholars of the period, had a great influence on both the scientific and political circles. For this reason, he could not be shared by different sect biographers. As a matter of fact, some Shafi'i tabaqat writers counted Ebu Ubeyd as a follower of Imam Shafii. On the other hand, some Hanbali scholars have mentioned Ebu Ubeyd among the class of Hanbali scholars. However, it was concluded that it would be more correct to see Ebu Ubeyd as an independent mujtahid rather than a follower of any madhhab. For, in his own works, the fact that he refers more to Imam Malik rather than Imam Shafii and Ahmad ibn Hanbal and sometimes refers to the views of Abu Hanifa and Imamey indicates this. Ebu Ubeyd, who came to the forefront with his faqih and muhaddis aspects, had a deep knowledge of the subject of naskh, which has a close relationship with these two sciences, and in this regard, he wrote a rare work called en-Nasih ve'l-mensu. fi'l-kur.ani'l-aziz ve ma fihi mine'l-fera'iz ve's-sunen. While revealing Ebu Ubeyd's understanding of naskh, his work en-Nasi. ve'l-mensu. was used as the main source. In addition to this, his other works related to the subject, especially his work called Kitabu'l- emval, were among the first hand sources that were consulted. It has been tried to determine his approach to naskh based on the statements he made on the subject and the examples he gave in this regard. In this context, Ebu Ubeyd's approach to the nature and framework of naskh and his views on the evidences that can abrogate each other are examined in this study. Ebu Ubeyd discussed the abrogation in a broader sense as "the modification of a shar'i ruling by a later evidence", not the established meaning in the methodology as "removal of a shar'i ruling with a later shar'i proof". In this context, naskh is also used for the allocation of public, the denial of the absolute, the statement of conciseness, the correction of a wrong understanding and the exception made from a general rule. This is known as the understanding of naskh among the companions, tabi`in and early convert scholars. However, although Ebu Ubeyd is at the same age as Imam Shafii and has copied and benefited from his works, it is noteworthy that he preferred the predecessor's approach to the subject rather than the naskh understanding he adopted. It is important to investigate this. He adopted the approach of the public regarding the Shari'a evidences of Ebu Ubeyd that could naskh each other. According to him, the verses of the Qur'an can naskh each other. He gave many examples of this. Another point that draws attention here is to ascribe the concept of naskh used for the verse of the Qur'an by Ebu Ubeyd, from the Lawh-i Mahfuz, in the form of a verse whose recitation is lasting and its meaning is naskhed, and a verse that is removed from people's hearts by canceling both its recitation and used in different meanings. Ebu Ubeyd stated that sunnah can be naskhed with sunnah, without making any distinction between ahad and mutawatir about sunnah and its naskh. However, despite giving many examples of the naskh of the ahad sunnah with its own like, no example has been encountered of the naskh of the ahad sunnah with its own like or with ahad and the ahad sunnah with the mutawatir sunnah. As it can be understood from my statements on the subject, Ebu Ubeyd saw that it is permissible to naskh both mutawatir and ahad sunnah with the Qur'an. However, while there is an example for the naskh of the ahad sunnah with the Qur'an in his related works, there is no example for the other. Although there is no clear statement on the issue that the Qur'an can be naskhed with the sunnah, it is understood from some examples that he gives permission for this.
Citation - WoS: 6
Citation - Scopus: 11
Activated Carbon-Coated Iron Oxide Magnetic Nanocomposite (ionps@ctac) Loaded With Morin Hydrate for Drug-Delivery Applications
(Frontiers Media Sa, 2024) Dogan, Yusuf; Ozic, Cem; Ertas, Erdal; Baran, Ayse; Rosic, Gvozden; Selakovic, Dragica; Eftekhari, Aziz; 06.02. Department of Plant Protection / Bitki Koruma Bölümü; 06. Faculty of Agricultural Sciences and Technologies in Kızıltepe / Kızıltepe Tarım Bilimleri ve Teknolojileri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Cancer is a major disease that affects millions of people around the world every year. It affects individuals of all ages, races, and backgrounds. Since drugs used to treat cancer cannot distinguish between cancerous and healthy cells, they cause systemic toxicity along with serious side effects. Recently, controlled drug-release systems have been developed to reduce the side effects caused by anticancer drugs used for treatment. Morin is an anticancer drug with a flavonol structure. It has been extensively researched for its antioxidant, anti-inflammatory, antitumoral, and antibacterial properties, especially found in Chinese herbs and fruits, and its multiple positive effects on different diseases. In this study, a nanocomposite with magnetic properties was synthesized by coating biocompatible activated carbon obtained using the fruits of the Celtis tournefortii plant on the surface of iron oxide magnetic nanoparticles. Characterization of the synthesized activated carbon-coated iron oxide magnetic nanocomposite was confirmed by Fourier transform infrared, scanning electron microscopy, energy-dispersive X-ray spectrometry, X-ray diffraction, dynamic light scattering, zeta potential, and vibrating sample magnetometry. The cytotoxic effects of the drug-loaded magnetic nanocomposite were examined in HT-29 (colorectal), T98-G (glioblastoma) cancer cell lines, and human umbilical vein endothelial cell (HUVEC) healthy cell line. The morin loading and release behavior of the activated carbon-coated iron oxide magnetic nanocomposite were studied, and the results showed that up to 60% of the adsorbed morin was released within 4 h. In summary, activated carbon-coated iron oxide magnetic nanocomposite carriers have shown promising results for the delivery of the morin drug.
Citation - WoS: 11
Citation - Scopus: 20
Activity of Metalaxyl-M plus mancozeb, Fosetyl-Al, and Phosphorous Acid against Phytophthora Crown and Root Rot of Apricot and Cherry Caused by Phytophthora palmivora
(CZECH ACADEMY AGRICULTURAL SCIENCES, 2017) Türkölmez, Şahimerdan; Derviş, Sibel; 16.01. Department of Organic Agriculture / Organik Tarım Bölümü; 16. School of Vocational Higher School of Kızıltepe/ Kızıltepe Meslek Yüksekokulu; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Crown and root rot, caused by the Oomycete pathogen Phytophthora palmivora, has become a destructive disease of apricot and cherry in eastern Turkey. There are no currently registered fungicides labeled for its control. In greenhouse experiments conducted in 2012 and 2013, 1-year-old potted apricot rootstock Zerdali and cherry rootstock Mahaleb plants were treated either with foliar spray of fosetyl-Al (140, 160, and 180 g a.i./100 l) or phosphorous acid (187.5, 200, and 215 g a.i./100 l) or soil drench of 100 ml of metalaxyl-M (= mefenoxam)+mancozeb (12+192, 16+256, and 20+320 g a.i./100 l) one day after wound inoculation of crowns and roots. In both years, phosphorous acid at 200 and 215 g a.i./100 l, fosetyl-Al at 160 and 180 g a.i./100 l, and metalaxyl-M+mancozeb at 20+320 g a.i./100 l significantly reduced the root rot severity on Zerdali by 70.68-80.00% and crown rot severity on both Zerdali and Mahaleb, by 68.32-91.96 and 74.21-82.60%, respectively, compared with phosphorous acid at 187.5 g a.i./100 l, fosetyl-Al at 140 g a.i./100 l, metalaxyl-M+mancozeb at 12+192 and 16+256 g a.i./100 l and control. Moreover, fosetyl-Al at 180 g a.i./100 l and metalaxyl-M+mancozeb at 20+320 g a.i./100 l significantly reduced the root rot severity on Mahaleb compared to fosetyl-Al at 140 and 160 g a.i./100 l, metalaxyl-M+mancozeb at 12+192 and 16+256 g a.i./100 l, phosphorous acid treatments and control in 2012, providing the best control of the disease by 88.00-90.68%. Two/three phosphorous acid foliar applications at 200 g a.i./100 l suppressed symptom development when field applications were made on a curative basis in 2014 and 2015.
Adapting To Conflict: Iran's Proxy Warfare Strategy in
(Kafkas University Iibf, 2025) Kazdal, Melıh; 04.03. Department of Political Science and International Relations / Siyaset Bilimi ve Uluslararası İlişkiler Bölümü; 04. Faculty of Economics and Administrative Sciences / İktisadi ve İdari Bilimler Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Bu çalışma İran’ın, Suriye ve Yemen’de vekalet savaşını nasıl kullandığını incelemektedir. Çalışmada vekalet savaşı kavramsal çerçevesi kullanılmış ve sahadaki uygulaması Andrew Mumford’un ortaya koyduğu dörtlü çerçeve olan, insan gücü temini, askeri malzeme temini, finansal yardım ve askeri olmayan yardım üzerinden incelenmiştir. Çalışmada, hem vakalar içindeki hem de vakalar arasındaki durumların incelenmesine olanak tanıyan çoklu vaka analizi yöntemi kullanılmıştır. Bu yaklaşımı kullanarak vakaların benzerliklerini, farklılıklarını ve altında yatan nedenleri ortaya koymak amaçlanmıştır. Suriye ve Yemen’in vaka analizi için seçilmesi, İran’ın bölgedeki vekalet savaşı stratejisinin değerlendirilmesine olanak tanıyan farklı çevresel ve sosyo-politik faktörlere dayanmaktadır. Çalışmanın zaman aralığı Arap Baharı sürecinin başlangıcından sonraki on yılı kapsamakta ve Kasım Süleymani'nin öldürülmesi ile sona ermektedir. Bu çalışma, İran’ın, esnek bir vekalet savaşı stratejisi kullandığını, değişen savaş dinamikleri ve çatışma noktalarına göre yaklaşımını değiştirdiğini göstermektedir.
Citation - WoS: 5
Citation - Scopus: 8
Adaptions in subsistence strategy to environment changes across the Younger Dryas-Early Holocene boundary at Kortiktepe, Southeastern Turkey
(Sage Journals, 2022) Emra, Stephanie; Benz, Marion; Sıddıq, Abu Bakar; Özkaya, Vecihi; 02.01. Department of Anthropology / Antropoloji Bölümü; 02. Faculty of Letters / Edebiyat Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
The site of Körtiktepe in southeastern Turkey is one of few sites in the Upper Mesopotamia basin that attests continuous, permanent occupation across the boundary from end of the colder, drier Younger Dryas (YD) into the comparatively wetter and warmer Early Holocene (EH). This allows for the study of the degree of environmental change experienced on a local level over this boundary as well as for the study of the adaptations that the occupants of the site undertook in response to these changes. The mammal assemblage of Körtiktepe remains relatively stable across the YD – EH transition with the main contributors to diet being mouflon (Ovis orientalis) and red deer (Cervus elaphus) in approximately the same quantities, although the contribution of aurochs (Bos primigenius) increases in the EH. The most significant changes can be seen in the shift in avifauna remains, with a sharp increase of waterbirds during the EH. It is proposed that these shifts reflect changes in the local environment with an increase in woodland cover as well as expansion of local waterways, which is generally consistent with previously published archaeobotanical studies. In terms of species exploited, mortality profiles as well as size distribution of mammals, a great deal of continuity is observed. This suggests that over this particular period the local impact of the beginning of the Early Holocene was not overly dramatic, allowing for cultural continuity of previously established subsistence strategies.
Citation - WoS: 48
Citation - Scopus: 51
Adolescent Transport and Unintentional Injuries: a Systematic Analysis Using the Global Burden of Disease Study 2019
(Elsevier Sci Ltd, 2022) Peden, Amy E.; Cullen, Patricia; Francis, Kate Louise; Moeller, Holger; Peden, Margaret M.; Ye, Pengpeng; Ivers, Rebecca Q.
Background Globally, transport and unintentional injuries persist as leading preventable causes of mortality and morbidity for adolescents. We sought to report comprehensive trends in injury-related mortality and morbidity for adolescents aged 10-24 years during the past three decades. Methods Using the Global Burden of Disease, Injuries, and Risk Factors 2019 Study, we analysed mortality and disability-adjusted life-years (DALYs) attributed to transport and unintentional injuries for adolescents in 204 countries. Burden is reported in absolute numbers and age-standardised rates per 100 000 population by sex, age group (10-14, 15-19, and 20-24 years), and sociodemographic index (SDI) with 95% uncertainty intervals (UIs). We report percentage changes in deaths and DALYs between 1990 and 2019. Findings In 2019, 369 061 deaths (of which 214337 [58%] were transport related) and 31.1 million DALYs (of which 16.2 million [52%] were transport related) among adolescents aged 10-24 years were caused by transport and unintentional injuries combined. If compared with other causes, transport and unintentional injuries combined accounted for 25% of deaths and 14% of DALYs in 2019, and showed little improvement from 1990 when such injuries accounted for 26% of adolescent deaths and 17% of adolescent DALYs. Throughout adolescence, transport and unintentional injury fatality rates increased by age group. The unintentional injury burden was higher among males than females for all injury types, except for injuries related to fire, heat, and hot substances, or to adverse effects of medical treatment. From 1990 to 2019, global mortality rates declined by 34.4% (from 17.5 to 11.5 per 100 000) for transport injuries, and by 47.7% (from 15.9 to 8.3 per 100000) for unintentional injuries. However, in low-SDI nations the absolute number of deaths increased (by 80.5% to 42 774 for transport injuries and by 39.4% to 31 961 for unintentional injuries). In the high-SDI quintile in 2010-19, the rate per 100 000 of transport injury DALYs was reduced by 16.7%, from 838 in 2010 to 699 in 2019. This was a substantially slower pace of reduction compared with the 48.5% reduction between 1990 and 2010, from 1626 per 100 000 in 1990 to 838 per 100 000 in 2010. Between 2010 and 2019, the rate of unintentional injury DALYs per 100 000 also remained largely unchanged in high-SDI countries (555 in 2010 vs 554 in 2019; 0.2% reduction). The number and rate of adolescent deaths and DALYs owing to environmental heat and cold exposure increased for the high-SDI quintile during 2010-19. Interpretation As other causes of mortality are addressed, inadequate progress in reducing transport and unintentional injury mortality as a proportion of adolescent deaths becomes apparent. The relative shift in the burden of injury from high-SDI countries to low and low-middle-SDI countries necessitates focused action, including global donor, government, and industry investment in injury prevention. The persisting burden of DALYs related to transport and unintentional injuries indicates a need to prioritise innovative measures for the primary prevention of adolescent injury. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd.
Adsorptive Performance of Magnetic Nano-Biosorbent for Binary Dyes and Investigation of Comparative Biosorption
(Springer Nature, 2019) Tural, B.; Boga, K.; Tural, S.; Tarhan, T.
The individual and competitive biosorption capacities of Metanil Yellow (MY) and Reactive Black 5 (RB5) by glutaraldehyde cross-linked magnetic chitosan nanoparticles (GMCNs) were studied. Competitive biosorption of the MY and RB5 dyes by the GMCNs has never been reported previously. Fourier transform infrared technique has been used to show the biosorbed MY and RB5 dyes onto GMCNs. During the studies, various essential factors influencing the biosorption, like adsorbate concentration, pH of the solution and contact time have been monitored. The equilibrium was achieved within 17 h for single dyes and 3 h for binary mixture at pH 3. The biosorption capacities were 620 mg/g for dye MY and 2549 mg/g for dye RB5 at pH 3, 30 °C. The second-order kinetic model has good compatibility with the dynamical biosorption behavior of a single dye and binary mixture. In order to study the competition biosorption of the RB5 and MY dyes in mixture solutions, the intraparticle diffusion model was used. Competition biosorption through analysis of the intraparticle diffusion model apparently favored the RB5 dye more than the MY dye on the GMCNs in mixture solutions. The biosorbent was regenerated efficiently through the alkaline solution and was then reused ten times for biosorption–desorption cycles. © 2018, Springer Nature Switzerland AG.
Citation - WoS: 2
Advanced Detection of Retinal Diseases Via Novel Hybrid Deep Learning Approach
(int information & Engineering Technology Assoc, 2023) Aykat, Sukru; Senan, Sibel; 08.01. Department of Computer Engineering / Bilgisayar Mühendisliği Bölümü; 08. Faculty of Engineering and Architecture / Mühendislik Mimarlık Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Diabetic drusen, choroidal neovascularization (CNV), and macular edema (DME) are some retinal diseases that can cause severe blindness and vision loss. Early diagnosis of retinal diseases is vital to prevent this irreversible damage to the eye. The problem statement of this study can be given as presenting new deep learning based results for detecting these retinal diseases. For this purpose, OCT dataset was used to detect CNV, DME and Drusen patients. This data set, which is frequently used in the literature, consists of CNV, DME, Drusen and Normal retina images. RestNet50, InceptionV3, InceptionResnetV2, MobileNet, DenseNet-201, Xception, EfficentNetB4, EfficentNetB7 and EfficentNetV2S models of the CNN architecture were applied to the data set and the performance results of these models were obtained. Then, in order to increase the classification performance of each of these models, hyperparameter tuning was performed by reducing the learning rate by half in each epoch. Later, a hybrid version of the EfficientNetV2S and Xception convolutional neural network models, the most successful of these hyperparameter-tuned models, was developed. The performance analysis results of our proposed hybrid deep learning model are given by comparing them with traditional deep learning models in the literature. These comparison results show that the classification success of the proposed model is higher than the success of traditional deep learning models in the literature. Thus, the proposed hybrid model can shorten the clinical diagnosis time. In addition, the costs of healthcare services can be reduced by intervening in treatable diseases earlier, instead of more costly interventions in the advanced stages of the disease.
Citation - WoS: 2
Citation - Scopus: 2
Air Quality Forecasting Using Machine Learning: Comparative Analysis and Ensemble Strategies for Enhanced Prediction
(Springer Int Publ Ag, 2025) Ozupak, Yildirim; Alpsalaz, Feyyaz; Aslan, Emrah; 08.01. Department of Computer Engineering / Bilgisayar Mühendisliği Bölümü; 08. Faculty of Engineering and Architecture / Mühendislik Mimarlık Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Air pollution poses a critical challenge to environmental sustainability, public health, and urban planning. Accurate air quality prediction is essential for devising effective management strategies and early warning systems. This study utilized a dataset comprising hourly measurements of pollutants such as PM2.5, NOx, CO, and benzene, sourced from five metal oxide sensors and a certified analyzer in a polluted urban area, totaling 9,357 records collected over one year (March 2004-February 2005) from the Kaggle Air Quality Data Set. A comprehensive comparison of ten machine learning regression models XGBoost, LightGBM, Random Forest, Gradient Boosting, CatBoost, Support Vector Regression (SVR) with Bayesian Optimization, Decision Tree, K-Nearest Neighbors (KNN), Elastic Net, and Bayesian Ridge was conducted. Model performance was enhanced through Bayesian optimization and randomized cross-validation, with stacking employed to leverage the strengths of base models. Experimental results showed that hyperparameter optimization and ensemble strategies significantly improved accuracy, with the SVR model optimized via Bayesian optimization achieving the highest performance: an R2 score of 99.94%, MAE of 0.0120, and MSE of 0.0005. These findings underscore the methodology's efficacy in precisely capturing the spatial and temporal dynamics of air pollution.
Al-Ikhwan Al-Safa' On The Ethical Dimensions Of Art: An Analysis On Music
(Ilahiyat Bilimleri Arastirma Vakfi, 2018) Kilic, Muhammet Fatih; 02.06. Department of Philosophy / Felsefe Bölümü; 02. Faculty of Letters / Edebiyat Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Since Ancient Geek philosophy, one of the most fundamental problems of the aesthetics has been the relationship between ethics and aesthetics. At the beginning of the questions that determine the nature of this relationship is the question of whether an object which is subjected to the judgment of beauty should have an ethically related content. Until modern times, this question has been answered to the point that, an object which is subjected to the judgment of beauty must also bear an ethical value. This answer states that in order to qualify an object or thing as beautiful in aesthetic sense, it should be connected to the good in ethical sense. From Ancient Greek philosophy to Islamic thought, we can clearly see the ideas and theories about this close relationship between ethics and aesthetics. This study aims to reveal the integrity between ethics and aesthetics in the philosophy of the al-Ikhwan al-Safa', a group of philosophers living in Basra and its environs during 4th/10th century, through the art of music. For this purpose, it is discussed in this article how music influences on human morality in their philosophy. The relationship between music and morality could be established in two ways in the philosophy of the al-Ikhwan: metaphysical and physical ways. When they connect music to metaphysics, they argue that music is a door to metaphysics, unlike the other arts. They refer to the strong effect of music in the human soul when they compare it with the other arts. As an auditory art, music has a richness of meaning that transcends the boundaries of the physical world and language. Through the sense of sight, one knows only what is at his side, but through the sense of hearing he may know the metaphysical truths that transcend time-space dimensions. As an art based on the sense of hearing, music can convey metaphysical truths to the audience differently from the other arts based on the sense of sight. Accordingly, music is a door for humans to direct them to the metaphysical truths and to enrich their morality. The al-Ikhwan al-Safa' assert that music has a divine and prophetic sources. These sources render it in relation to the wisdom. This thought about the source of the music also provides an explanation of the legitimacy of music. In order to emphasize this ground of legitimacy, they give some examples of usage of music used during religious rituals. They also argue that music in these rituals enriches human's morality. Another dimension as a metaphysical level for the relation between music and ethics in the philosophy of the al-Ikhwan is the mathematical basis of music. According to them, mathematics is the first path to the discovery of divine wisdom. This is because God has created the world in a harmony with the supreme proportions that describe the specific relation between the world and the numbers. Music is an art that is located in mathematics and that these supreme proportions could be obviously seen. Accordingly, music presents definitively the truth, divine wisdom and secrets. The al-Ikhwan argue that music is similar and harmonious with the sounds that emerge from the movements of stars and planets. The happiness in the celestial world where there is no generation and corruption is reproduced by the artist in the world of generation and corruption through music. Thus, music increases the desire to rise to the celestial world. This desire is described by the al-Ikhwan as trying to resemble to God. This description demonstrate that they evaluate the nature of music in a metaphysical context. Consequently, performing music, according to them, creates a result that redirects the human to the metaphysics. This metaphysical redirection does not only have a theoretical dimension in the sense that one acquires knowledge of the truth, but also has a practical content in the act of human in the sense of the resemblance to God. This practical content concerns the moral development of a person. Regarding the relation between music and morality, the al-Ikhwan al-Safa' offer a physics-based explanation in addition to these metaphysical bases. They argue that music creates psycho-physiological effects on humans and that the melodies coming out of the strings of the lute influence the four elements; blood, yellow bile, black bile, and phlegm in the human body. The background of this explication is the Hippocratic-Galician medical theory, which has become widespread in the Islamic world since the ninth century. Within this theory, they reveal that music influences the physical and psychological states of human and that it can create permanent moral virtues such as courage, generosity, chastity, and mercifulness.
Alman Oryantalizmi ve İslami Dönem Fars Edebiyatı: Bir Literal Geçişkenlik Örneği Olarak Josef von Hammer-Purgstall (1774–1856)
(2019) Avcı, Remzi; 02.14. Department of History / Tarih Bölümü; 02. Faculty of Letters / Edebiyat Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Avrupa‘da İslami dönem Fars dili, kültür ve edebiyatına duyulan ilginin tarihi oldukça eski bir geleneğe dayanmaktadır. Çeviri hareketleri bağlamında düşünüldüğünde İslami dönem Fars edebiyatının Avrupa ile metinsel temasının 17. yüzyılda başladığı söylenebilir. Coğrafya ve kültüre duyulan yakın ilgi seyyahların dil ve edebiyata ilgisini de beraberinde getirmiştir. Bu dönemde birçok Alman seyyah Safevi ülkesine seyahat etmiş ve tarih, kültür, dil ve İslami dönem Fars edebiyat üzerine geniş bilgiler toplayarak bunları Batı’ya aktarmıştır. 1634 yılında Fars edebiyatı klasiklerinden olan Şeyh Sa‘dî-i Şîrâzî’nin Gülistan adlı eseri Fransız oryantalist André du Ryer (1580-1660) tarafından Fransızcaya çevrilmiştir. Friedrich Ochsenbach (1606–1658), söz konusu çeviriyi 1636 yılında Fransızcadan Gulistan, das ist, Königlicher Rosengarten/Gülistan, Kraliyet Gül Bahçesi başlığı ile Almancaya çevirmiştir. Safevi ülkesinde medreselerde Farsça öğrenerek Sa‘dî’nin eserleri ile tanışmış olan Adam Olearius/Ölschläger (1600–1671), Almanya’ya döndükten sonra Safevi elçisinin yardımıyla Gülistan’ı 1654 yılında Persianische Rosenthal/Fars Güller Vadisi adıyla Almancaya çevirmiştir. 18. yüzyılın sonlarına doğru Avrupa’da Hâfız-ı Şîrâzî ve Şeyh Sa‘dî-i Şîrâzî gibi İslami dönem Fars şairlerinden Batı dillerine yapılan edebi metin çevirilerdeki artış oryantalistlerden şairlere kadar Almanca konuşulan dünyada da etkisini göstermiştir. Bu zaman dilimi Doğu ve Batı arasında ilişkide bir dönüm noktası olarak düşünülebilir. 19. yüzyılın ise ilk yıllarında diplomat, seyyah, tüccar ve oryantalistlerin yaptıkları çeviriler ile başlayan ve gelişen edebî oryantalizm Almanca konuşulan dünyada Doğu’dan Batı’ya bir Fars şiiri çeviri külliyatı bırakmıştır. Söz konusu külliyatın oluşumunda oldukça önemli bir yerde duran Avusturyalı oryantalist Josef von Hammer-Purgstall (1774-1856), Vinzenz Rosenzweig von Schwannau (1791-1865), Valentin von Huszár (1788-1850), Johann Wolfgang von Goethe (1749-1832), Friedrich Rückert (1788-1866) ve August von Platen (1796-1835) gibi aydınlanmacı, klasik ve romantik akımdan ve birçok düşünür şair ve oryantalistin Fars dili ve şiirine ilgi duymalarında önemli bir etki bırakmıştır. Hammer-Purgstall’ın İslami dönem Fars şiiri çevirilerinden literal bir ağ yarattığınıiddia eden bu çalışma, onun çevirilerinin Alman edebi oryantalizminin inşa ve kurumsallaşmasında nasıl bir rol oynadığını incelemektedir
Citation - WoS: 17
Citation - Scopus: 15
Alpha-lipoic acid may ameliorate testicular damage by targeting dox-induced altered antioxidant parameters, mitofusin-2 and apoptotic gene expression
(Andrologia, 2021) Güzel, Elif Erdem; Kaya Tektemur, Nalan; Tektemur, Ahmet; 09.02. Department of Midwifery/ Ebelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
In the study, the ameliorating effects of alfa lipoic acid (ALA) against doxorubicin-induced testicular apoptosis, oxidative stress and disrupted mitochondrial fusion were investigated in male rats. Rats were divided into four groups as control, doxorubicin (DOX), DOX + ALA and ALA. A single dose of 15 mg/kg DOX was administered i.p to the DOX and DOX + ALA groups. 50 mg/kg ALA was given to the DOX + ALA and ALA groups by oral gavage every other day. After 28 days, rat testes and serum samples were collected and analysed. Administration of DOX alone caused a decrease in body and relative testicular weights, seminiferous tubule diameter and germinal epithelium thickness, Johnsen's score and serum testosterone levels. DOX treatment led to severe testicular damage such as tubular degeneration, and atrophic tubules. Also, the activities of superoxide dismutase and glutathione peroxidase were reduced, while the level of malondialdehyde was increased in the testis. The mRNA levels of apoptotic-related genes (CASP3, TP53, BAX, BCL2) and apoptotic index were increased, while mitofusin-2 decreased. DOX caused an increase in CASP3 and a decrease in mitofusin-2 immunoreactivities. Treatment with ALA markedly improved all of DOX-induced biochemical, histochemical and molecular alterations in rat testis. Consequently, ALA has a therapeutic role in ameliorating DOX-induced testicular damage in rats.
Altın Nanopartiküllerin Yeşil Sentezi, Karakterizasyonu ve Biyouyumlu Yapılarının Biyomedikal Uygulamalarda (antibakteriyel, Antifungal ve Antikanser) Değerlendirilmesi
(Kahramanmaras Sutcu Imam Univ Rektorlugu, 2023) Baran, Ayse; Keskin, Cumali
Gold nanoparticles (AuNPs) stand out due to their low toxicity and high compatibility, and the large and modifiable surface areas they provide. In this study, the leaves of Celtis tournefortii Lam. (CT) were used for the green synthesis of gold nanoparticles (AuNPs) first time. The size, shape, surface charge, and functionality of the synthesized AuNPs are described in detail. The suggested mechanisms of action on the tested target cells are highlighted. The biological activities (antibacterial, antifungal, and anticancer) of "green" AuNPs and their further biomedical application possibilities are also discussed. Synthesized AuNPs displayed a spherical appearance, surface plasmon resonance band at 553.67 nm wavelength, and surface charge of -16.53 mV. Particle morphology, size, and surface charge were observed to be affected by the leaf extract used in the reduction reaction. FTIR and TGA-DTA data revealed that functional groups from the CT extract participate in the synthesis and stabilization of AuNPs. AuNPs showed antibacterial and antifungal effects on all the strains and yeast tested by microdilution method (MIC). AuNPs showed dose-dependent cytotoxic activity on cancerous cell lines (SKOV-3, CaCo2, and U118). The obtained results highlight a potentially low-cost green synthesis method using CT leaf extract to synthesize AuNPs showing important biological properties.
Ameliorative Effects of Agomelatine Against Doxorubicin-Induced Hepatotoxicity
(BMC, 2025) Savas, Hasan Basri; Sozen, Mehmet Enes; Cuce, Gokhan; Batur, Tuba
Drug-induced hepatotoxicity is a significant impediment to the use of doxorubicin, a commonly employed chemotherapeutic agent with established efficacy in cancer treatment. The present study aimed to determine the potential protective effects of agomelatine against doxorubicin hepatotoxicity in rat toxicity models. Thirty-two rats were divided into four groups: control (with saline administration), Doxo (with 40 mg/kg doxorubicin administration), Doxo + Ago20, and Doxo + Ago40 (with 20 and 40 mg/kg agomelatine administration and 40 mg/kg doxorubicin administration). On the day of 14 rats were sacrificed, samples were collected for comparison of immunohistochemical, hematological, and biochemical analysis. There were statistically significant differences between the study groups in terms of immunohistochemical, hematological, and biochemical parameters. Agomelatine administration reduced the TNF-alpha, and caspase-3, which increased by doxorubicin, and reversed levels of oxidative stress markers altered by doxorubicin (p < 0.05). Doxorubicin induces oxidative stress, apoptosis, and hepatotoxicity. Agomelatine may be favored as a primary antidepressant to mitigate hepatic damage induced by doxorubicin.

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