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Citation - WoS: 5
Citation - Scopus: 5
1-6 Years Aged Childrens Mothers' First Aid for Burns Observation in Mardin City Center
(derman Medical Publ, 2013) Demir, Cemil; Sahin, Deniz Say; Battaloğlu İnanç, Betül; Department of Medical Services and Techniques / Tıbbi Hizmetler ve Teknikleri Bölümü; Department of Nursing / Hemşirelik Bölümü
Aim: In this study, we aimed to determine the mothers knowledge levels about burns and first aid. When they encounter burns, what will they do in the first instance and emergency application. At the end of this research correct information given to mothers. Aimed to supply the deficiency information. Material and Method: 25-49 age group of mothers who have 1-6 years aged childrens in the study were choisen ramdomly. After being informed about the study, only volunteries for questionnaires were used. There were a thousand mothers. Results: Children 21.6 % have burns. 81.4% burns were in their house , 18.6 % burns were out of their house. Often burns case were 2-4 years aged group children. 89.6 % mothers found themselves have no true knowledge about first aid for burns. Discussion: Mothers knowledge more deficient about the first aid for the burns. In this regard mothers lack of knowledge must be correct with the training activities to be applied. Prime necessity of the mothers were informed about the right applications.
19. Yüzyıl Vanı’nda Âyan Bir Aile: Timurpaşazâdeler
(2022) Çiftçi, Erdal; Department of Architecture and Urban Planning / Mimarlık ve Şehir Planma Bölümü
Bu çalışma 18. yüzyılın son çeyreğinden 19. yüzyılın ortasına kadar Van yönetiminde bulunan ve bu tarihten sonra da Van’da etkili olmaya devam eden ayan bir ailenin yerel siyasetteki rolüne odaklanmaktadır. Ayanlar çağı olarak bilinen 18. yüzyılda Osmanlı imparatorluğunda güçlenmiş olan ayanlarla ilgili literatüre mikro bir çalışma ile Van örneği üzerinden katkı sunulması amaçlanmaktadır. Van’da Timurpaşazadeler ismi ile ayanlaşan bir ailenin güçlenerek ortaya çıkışı, Tanzimat öncesi ve sırasında yaşanan tepkiler ve Tanzimat sonrasında bu ayan ailenin yeni düzen içerisindeki aktif yer alışı incelenmektedir. Tanzimat düzeninin bu gibi ayan aileleri yaptırımcı, tek taraflı ve üstten bir yaklaşımla izale ederek uygulamaya dökülebildiği görüşü son dönemlere kadar literatürün baskın tezlerinden biriydi. Fakat son dönemlerde yapılan yeni çalışmalardan ve Van örneğinden de görüleceği üzere Tanzimat merkezileşmesi yerel ayan ailelerin mülki idari güçlerine belirli oranda bir sınır uygulamış olsa da Timurpaşazadeler yeni düzenin uygulanmasında aktif rol oynamaya devam etmişlerdir. Timurpaşazadelerin bir eşraf olarak kendi rol ve çıkarlarını yeni düzen içerisinde aramaya devam ettikleri anlaşılmaktadır. Dersaadet’in Timurpaşazadeleri Van’dan kaldırmamış olması ve Timurpaşazadelerin bazı Van valileri ile yakın ilişkilerini sürdürmesi bu durumun önünü açan sebeplerden birkaçıdır.
1933 Londra Para ve İktisat Konferansı’nda Türkiye
(2024) Meraklı, Erdem; Meraklı, Erdem; Department of History / Tarih Bölümü
Bu çalışmanın amacı, 1929 Dünya Ekonomik Krizi’ne karşı uluslararası ortak çözümler bulunması düşüncesiyle Milletler Cemiyeti tarafından toplanan 1933 Londra Para ve İktisat Konferansı’nın gündem maddelerini ve sonuçlarını, Türkiye’de Cumhuriyet’in ilk yıllarında izlenen ekonomi politikaları açısından değerlendirmektir. Büyük Buhran’ın etkili olduğu yıllarda devletler, krize karşı mücadele ederken birbirlerinden bağımsız iktisat politikaları izliyorlardı. Fakat bu durum sorunları çözmediği gibi, ekonomik krizi daha da derinleştiriyordu. Bu noktada konferanstan beklenen; ABD, Büyük Britanya ve Fransa gibi büyük devletlerin para politikaları ile gümrük duvarları üzerindeki anlaşmazlıklarının sona erdirilmesi ve küresel ekonomik krize karşı ortak önlemlerin alınmasıydı. Ancak konferans sonunda para politikalarında bir uzlaşmaya varılamadı ve konferansta imzalanan Gümrük Ateşkesi’nin ömrü ise sadece birkaç ay oldu. Diğer yandan konferansın katılımcı ülkelerinden Türkiye, bu dönemde gümrük duvarlarını yüksek tutuyor ve para politikalarında devalüasyon karşıtı bir siyaset benimsiyordu. Bu politika esasen, “merkezdeki” sanayileşmiş devletlerin aleyhine, Birinci Dünya Savaşı’ndan sonra dünya genelinde işleyen sürecin bir parçasıydı. Çalışma ile ulaşılan sonuçlardan biri, Londra Konferansı’ndaki görüş ayrılıklarının, uluslararası konjonktürde Türkiye gibi bağımsız iktisat politikaları izlemek arzusunda olan “çevre” ülkelere avantaj sağladığı yönündedir. Makale ile varılan bir başka sonuç ise, küresel ekonomide Birinci Dünya Savaşı ile başlayıp 1929 Krizi ile hızlanan değişim sürecinin 1933’te Londra Konferansı’nda gün yüzüne çıkmış olmasıdır.
(3 + 1) Boyutlu B Tipi Kadomtsev-petviashvili Denklemi için Geliştirilmiş Bernoulli Alt Denklem Fonksiyon Yöntemi ile Elde Edilmiş Tam Çözümler
(2019) Düşünceli, Faruk; Department of Economics / İktisat Bölümü
Bu çalışmada (3 + 1) boyutlu B tipi Kadomtsev-Petviashvili denkleminin tam çözümleri için geliştirilmiş Bernoulli alt denklem fonksiyon yöntemini kullandık. Bazı yeni çözümler elde ettik. Bütün hesaplamaları ve grafik çizimlerini Wolfram Mathematica programı yardımıyla yaptık.
Citation - WoS: 1
Citation - Scopus: 3
A hybrid approach consisting of 3D depthwise separable convolution and depthwise squeeze‑and‑excitation network for hyperspectral image classifcation
(Springer Heidelberg, 2024) Asker, Mehmet Emin; Güngör, Mustafa; Gungor, Mustafa; Department of Electricity / Elektrik Bölümü
Hyperspectral image classification is crucial for a wide range of applications, including environmental monitoring, precision agriculture, and mining, due to its ability to capture detailed spectral information across numerous wavelengths. However, the high dimensionality and complex spatial-spectral relationships in hyperspectral data pose significant challenges. Deep learning, particularly Convolutional Neural Networks (CNNs), has shown remarkable success in automatically extracting relevant features from high-dimensional data, making them well-suited for handling the intricate spatial-spectral relationships in hyperspectral images.This study presents a hybrid approach for hyperspectral image classification, combining 3D Depthwise Separable Convolution (3D DSC) and Depthwise Squeeze-and-Excitation Network (DSENet). The 3D DSC efficiently captures spatial-spectral features, reducing computational complexity while preserving essential information. The DSENet further refines these features by applying channel-wise attention, enhancing the model's ability to focus on the most informative features. To assess the performance of the proposed hybrid model, extensive experimental studies were carried out on four commonly utilized HSI datasets, namely HyRANK-Loukia and WHU-Hi (including HongHu, HanChuan, and LongKou). As a result of the experimental studies, the HyRANK-Loukia achieved an accuracy of 90.9%, marking an 8.86% increase compared to its previous highest accuracy. Similarly, for the WHU-Hi datasets, HongHu achieved an accuracy of 97.49%, reflecting a 2.11% improvement over its previous highest accuracy; HanChuan achieved an accuracy of 97.49%, showing a 2.4% improvement; and LongKou achieved an accuracy of 99.79%, providing a 0.15% improvement compared to its previous highest accuracy. Comparative analysis highlights the superiority of the proposed model, emphasizing improved classification accuracy with lower computational costs.
Abelmoschus Esculentus Yaprağı Kullanılarak Gümüş Nanopartiküllerin Yeşil Sentezi ve Bazı Gıda Patojenleri Üzerindeki Antimikrobiyal Etkileri
(2021) Hatipoğlu, Abdulkerim; Department of Nutrition and Dietetics/ Beslenme ve Diyetetik Bölümü
Bu çalışmada, Abelmoschus esculentus (AE) yaprağı özütü kullanılarak düşük maliyetli, çevre dostu ve kolay bir şekilde gümüş nanopartiküller (AgNP’ler) sentezlendi. Ultraviyole-görünür (UV-vis.) Spektrofotometre analiz verilerine göre, nanokristaller 431 nm'de karakteristik bir tepe noktası gösterdi. Taramalı Elektron Mikroskobu (SEM), Transmisyon Elektron Mikroskobu (TEM) ve enerji dağılımlı X-Işını Spektroskopisi (EDX) analizleri, biyolojik yolla sentezlenen AgNP'lerin morfolojik yapılarının küresel olduğunu ortaya koydu. XRD analizi sonuçlarına göre AgNP'lerin kristal yapılarının kübik olduğu görüldü. Nanopartiküllerin boyutu, Debye-Scherrer denklemi ile 19.05 nm olarak hesaplandı. Sentezlenen nanomalzemenin zeta potansiyeli -9.83 mV ve zeta boyutu da 142.2 nm olarak ölçüldü. AgNP'lerin, gıda patojenlerinden Staphylococcus aureus ATCC 29213, Escherichia coli ATCC25922, Bacillus subtilis ATCC11774, Pseudomonas aeruginosa ATCC27833 ve Candida albicans üzerindeki Minimum İnhibitör Konsantrasyonu (MİK) değerlerinin (mg/mL) sırasıyla 0.125, 0.50, 0.0312, 0.125 ve 0.125 düzeyinde olduğu tespit edildi.
Citation - WoS: 0
Citation - Scopus: 0
Ability of Cha2ds2-vasc/R2cha2ds2-vasc Scores To Predict Complications Related To Cardiac Implantable Electronic Devices
(Wiley, 2025) Soner, Serdar; Aktan, Adem; Aktan, Adem; Kilic, Raif; Guzel, Hamdullah; Tastan, Ercan; Oksul, Metin; Guzel, Tuncay; Department of Internal Medical Sciences / Dahili Tıp Bilimleri Bölümü
BackgroundGlobally, the number of cardiac implantable electronic devices (CIEDs) is increasing. In our study, we aimed to investigate whether CHA(2)DS(2)-VASc and R(2)CHA(2)DS(2)-VASc scores are predictive of CIED-related complications. MethodsOur investigation was carried out with a multicenter retrospective design. Patients who underwent CIED surgery at two cardiac centers in Turkey between January 2011 and May 2023, 1676, were evaluated. The patients were divided into two groups according to their R(2)CHA(2)DS(2)-VASc scores. Patients with R(2)CHA(2)DS(2)-VASc >= 5 were included in group 1 (380 patients), and patients with R(2)CHA(2)DS(2)-VASc < 5 (1296 patients) were included in group 2. The primary outcome was defined as the cumulative events. Each component of cumulative events, such as hematoma, pericardial effusion, pneumothorax, and infection, was also defined as a secondary outcome. ResultsThe study's patient population had an average age of 62.9 +/- 14 years. Pneumothorax (1.8% vs. 1.3%, p = 0.444), pericardial effusion or tamponade (0.35% vs. 0.2%, p = 0.659), and clinically significant hematoma (1.1% vs. 0.6%, p = 0.376) were comparable between the groups. Infection-related devices and cumulative events classified as primary outcomes were higher in the R(2)CHA(2)DS(2)-VASc >= 5 group (6.1% vs. 1.2%, p < 0.001; 7.6% vs. 3.2%, p < 0.001, respectively). Modeling analyses showed that the CHA(2)DS(2)-VASc score and HT were also independent predictors of device-related infection and cumulative events. ConclusionIn the R(2)CHA(2)DS(2)-VASc >= 5 groups, infection related to the device system and cumulative events were higher. Patients with an R(2)CHA(2)DS(2)-VASc score of 5 or more and a high CHA(2)DS(2)-VASc score should be evaluated more carefully regarding infection and cumulative events before and after the operation.
Citation - WoS: 0
Citation - Scopus: 0
Abnormal Heart Sound Detection Using Ensemble Classifiers
(Institute of Electrical and Electronics Engineers Inc., 2019) Zan, H.; Yildiz, A.; Zan, Hasan; Department of Computer Engineering / Bilgisayar Mühendisliği Bölümü
Phonocardiogram is used for ambulatory diagnostic to assess health status of heart and detect cardiovascular disease. The goal of this study is to develop automatic classification method of PCG recordings collected from different databases and recorded in a different way. For this purpose, after various time and frequency domain features are extracted from PCG recordings obtained from two databases, recordings are subjected to pre-classification in order determine which database they are obtained from. Before final classification, various time, frequency and time-frequency domain features of classified recordings are extracted. These features are fed into four different classification ensembles trained with training dataset. With final decision rule, proposed algorithm achieved an accuracy of 98.9%, a sensitivity of 93.75% and a specify of 99.5%. © 2018 IEEE.
Citation - WoS: 0
Citation - Scopus: 0
Abu Ubayd’s Understanding Of Naskh;
(Hitit University, 2022) Yaşar, Mehmet Aziz; Nas, Taha; Department of Basic Islamic Sciences / Temel İslam Bilimleri Bölümü
In the period when Islamic sciences were formed, a large number of scholars with absolute ijtihad capacity were trained. One of the scholars mentioned is Abu ‘Ubayd al-Qāsim ibn Sallām al-Khurāsānī al-Harawī who was educated by many famous scholars of the period, had a great influence on both the scientific and political circles. For this reason, he could not be shared by different sect biographers. As a matter of fact, some Shafi’i tabaqat writers counted Ebû Ubeyd as a follower of Imam Shafii. On the other hand, some Hanbali scholars have mentioned Ebû Ubeyd among the class of Hanbali scholars. However, it was concluded that it would be more correct to see Ebû Ubeyd as an independent mujtahid rather than a follower of any madhhab. For, in his own works, the fact that he refers more to Imam Malik rather than Imam Shafii and Ahmad ibn Hanbal and sometimes refers to the views of Abu Hanifa and Imamey indicates this. Ebû Ubeyd, who came to the forefront with his faqih and muhaddis aspects, had a deep knowledge of the subject of naskh, which has a close relationship with these two sciences, and in this regard, he wrote a rare work called en-Nâsiḫ ve’l-mensûḫ fi’l-Ḳurʾâni’lʿazîz ve mâ fîhi mine’l-ferâʾiż ve’s-sünen. While revealing Ebû Ubeyd’s understanding of naskh, his work en-Nâsiḫ ve’l-mensûḫ was used as the main source. In addition to this, his other works related to the subject, especially his work called Kitâbu’l-emvâl, were among the first hand sources that were consulted. It has been tried to determine his approach to naskh based on the statements he made on the subject and the examples he gave in this regard. In this context, Ebû Ubeyd’s approach to the nature and framework of naskh and his views on the evidences that can abrogate each other are examined in this study. Ebû Ubeyd discussed the abrogation in a broader sense as “the modification of a shar’i ruling by a later evidence”, not the established meaning in the methodology as “removal of a shar’i ruling with a later shar’i proof”. In this context, naskh is also used for the allocation of public, the denial of the absolute, the statement of conciseness, the correction of a wrong understanding and the exception made from a general rule. This is known as the understanding of naskh among the companions, tābi‘īn and early convert scholars. However, although Ebû Ubeyd is at the same age as Imam Shafii and has copied and benefited from his works, it is noteworthy that he preferred the predecessor’s approach to the subject rather than the naskh understanding he adopted. It is important to investigate this. He adopted the approach of the public regarding the Shari’a evidences of Ebû Ubeyd that could naskh each other. According to him, the verses of the Qur’an can naskh each other. He gave many examples of this. Another point that draws attention here is to ascribe the concept of naskh used for the verse of the Qur’an by Ebû Ubeyd, from the Lawh-i Mahfuz, in the form of a verse whose recitation is lasting and its meaning is naskhed, and a verse that is removed from people’s hearts by canceling both its recitation and used in different meanings. Ebû Ubeyd stated that sunnah can be naskhed with sunnah, without making any distinction between ahad and mutawatir about sunnah and its naskh. However, despite giving many examples of the naskh of the âhâd sunnah with its own like, no example has been encountered of the naskh of the âhâd sunnah with its own like or with âhâd and the âhâd sunnah with the mutawatir sunnah. As it can be understood from my statements on the subject, Ebû Ubeyd saw that it is permissible to naskh both mutawatir and ahad sunnah with the Qur’an. However, while there is an example for the naskh of the ahad sunnah with the Qur’an in his related works, there is no example for the other. Although there is no clear statement on the issue that the Qur’an can be naskhed with the sunnah, it is understood from some examples that he gives permission for this. © Published by Hitit Ü niversitesi İlahiyat Fakültesi – Hitit University Divinity Faculty, Çorum, Turkey. All rights reserved.
Açık Bir Ekonomide Toplam İstikrarsızlığın Test Edilmesi
(2022) Yılmaz, Yusuf Ömür; Department of Economics / İktisat Bölümü
Bu makale, alternatif para politikası kuralları altında pozitif uzun vadeli enflasyon oranı ve güneş lekesi şoku içeren küçük bir açık ekonomi Yeni-Keynesyen modeli kullanarak 2010 ve 2016 yılları arasında Türk ekonomisinin istikrarını ampirik olarak test etmektedir. Belirsizlik olasılıklarının bire çok yakın olduğu bulunmuştur. Bu dönemde ekonominin istikrarsız olduğu sonucuna varılabilir çünkü Merkez Bankası'nın enflasyona zayıf tepki vermesine rağmen uzun vadeli enflasyon oranı yüksek tek hanelidir. Bu durum ekonomiyi genel istikrarsızlığa sürüklemiştir.
Acil Servis Kalabalıklığının Nedenleri ve Çözüm Önerileri: Sağlık Personeli Perspektiflerinin Nitel Bir Çalışması
(2023) Bütün, Ahmet; Department of Nursing / Hemşirelik Bölümü
Giriş: Acil servislerin aşırı kalabalıklığı küresel bir sorundur. Bu durum uzun bekleme süresi, hastaların ve sağlık personelinin memnuniyetinin azalması, acil bakıma en çok ihtiyaç duyan hastaların tedavisinin gecikmesi, sağlanan sağlık hizmetinin kalitesinin düşmesi ve sağlık bakım maliyetlerinin artması gibi birçok olumsuz sonuca yol açmaktadır. Bu çalışmanın amacı, hastaların acil servisleri neden kullanmayı tercih ettiklerini, acil sağlık hizmetlerinin güncel sorunlarını belirlemek ve acil servislerin kalabalıklığını ve buna bağlı sorunları hafifletmek için acil servis sağlık personelinin bakış açılarından çözüm geliştirmektir. Yöntem: Bu çalışmada nitel desen kullanılmıştır. 20 Aralık 2021-18 Şubat 2022 tarihleri arasında 22 acil servis sağlık personeli ile derinlemesine yarı yapılandırılmış görüşmeler gerçekleştirilmiştir. Verilerin analizinde tematik analiz yöntemi kullanılmıştır. Bulgular: 22 acil servis sağlık personeli ile mülakat yapıldı; 16'sı erkek, 6'sı kadındı. Acil servis sağlık personeli görüşmeleri, acil serviste en az 1 yıllık iş deneyimine sahip 14 acil servis hemşiresi, 6 acil servis doktoru ve 2 acil tıp uzmanı ile cinsiyetleri veya yaşları dikkate alınmadan gerçekleştirilmiştir. Veri analizi sonucunda 5 ana tema belirlenmiştir: Yetersiz sağlık sistemi, hastayla ilgili sorunlar, acil servislerin avantajları, acil servislerin aşırı kalabalıklığının sonuçları ve acil servis kalabalıklığı için çözümler. Sonuç: Sağlık sistemindeki çeşitli yetersizlikler, acil servislerin avantajlarının olması ve hastaların sağlık hizmetlerini kullanma konusundaki algıları acil servislerin hastalar tarafından kullanımını arttırmış ve bu durum acil servislerde kalabalıklaşmaya sebep olmuştur. Acil servislerin kalabalıklığını hafifletmek için etkili çözümlere ihtiyaç vardır. Acil olmayan acil servis ziyaretlerini azaltmaya yönelik önlemler yeterli değildir. Acil servislerdeki kalabalıklığı azaltmak için birçok faktörün göz önünde bulundurulması ve hepsinin birlikte uygulanması gerekmektedir.
Citation - WoS: 2
Citation - Scopus: 3
Activated Carbon-Coated Iron Oxide Magnetic Nanocomposite (ionps@ctac) Loaded With Morin Hydrate for Drug-Delivery Applications
(Frontiers Media Sa, 2024) Dogan, Yusuf; Ozic, Cem; Ertas, Erdal; Baran, Ayse; Rosic, Gvozden; Selakovic, Dragica; Eftekhari, Aziz; Doğan, Yusuf; Baran, Ayşe; Department of Plant Protection / Bitki Koruma Bölümü
Cancer is a major disease that affects millions of people around the world every year. It affects individuals of all ages, races, and backgrounds. Since drugs used to treat cancer cannot distinguish between cancerous and healthy cells, they cause systemic toxicity along with serious side effects. Recently, controlled drug-release systems have been developed to reduce the side effects caused by anticancer drugs used for treatment. Morin is an anticancer drug with a flavonol structure. It has been extensively researched for its antioxidant, anti-inflammatory, antitumoral, and antibacterial properties, especially found in Chinese herbs and fruits, and its multiple positive effects on different diseases. In this study, a nanocomposite with magnetic properties was synthesized by coating biocompatible activated carbon obtained using the fruits of the Celtis tournefortii plant on the surface of iron oxide magnetic nanoparticles. Characterization of the synthesized activated carbon-coated iron oxide magnetic nanocomposite was confirmed by Fourier transform infrared, scanning electron microscopy, energy-dispersive X-ray spectrometry, X-ray diffraction, dynamic light scattering, zeta potential, and vibrating sample magnetometry. The cytotoxic effects of the drug-loaded magnetic nanocomposite were examined in HT-29 (colorectal), T98-G (glioblastoma) cancer cell lines, and human umbilical vein endothelial cell (HUVEC) healthy cell line. The morin loading and release behavior of the activated carbon-coated iron oxide magnetic nanocomposite were studied, and the results showed that up to 60% of the adsorbed morin was released within 4 h. In summary, activated carbon-coated iron oxide magnetic nanocomposite carriers have shown promising results for the delivery of the morin drug.
Citation - WoS: 0
Actors: Kurdish National, Religious and Economic Blocs
(I B Tauris & Co Ltd, 2017) Çiçek, Cuma; Department of Political Science and International Relations / Siyaset Bilimi ve Uluslararası İlişkiler Bölümü
[No Abstract Available]
Citation - WoS: 0
Citation - Scopus: 0
Acute Cyanide Intoxication Due To Apricot Seed Ingestion
(Soc Argentina Pediatria, 2024) Talay, Mehmet Nur; Orhan, Özhan; Orhan, Ozhan; Department of Internal Medical Sciences / Dahili Tıp Bilimleri Bölümü
Introduction : Cyanide poisoning, whether it be accidental or intentional, remains a significant danger to adults and children, especially in societies where agriculture is a primary source of income. We examined the clinical follow-up, complications, and results of cyanide poisoning cases that occurred after eating the pits and seeds of plants containing cyanide glycosides, such as apricot kernels and almonds. Methods : Between 01/01/2017 and 01/08/2022, 14 children aged 1-18 years who were followed up with a prediagnosis of cyanide poisoning in our Paediatric Intensive Care Unit (PICU) were retrospectively analysed. Results : Eight of the patients followed with a preliminary diagnosis of cyanide poisoning were female and six were male. The most common admission month was July (42.8%) coinciding with the agricultural season. The most common symptoms at presentation were weakness and fatigue (n = 7). In the PICU, 4 patients presented lip cyanosis; 3, altered level of consciousness. Vomiting, seizure, headache, dizziness and palpitatons were less frequent. Four patients were treated with hydroxocobalamin (Cyanokit (R) ) as an antidote due to acidosis in their blood gases. All patients treated for cyanide poisoning were discharged. Conclusions : Cyanide poisoning should be considered in paediatric patients with suspicious findings, sudden loss of consciousness, increased anion gap acidosis and lactic acidosis. The history of eating the seeds of plants such as apricot and almonds should be investigated .
Citation - WoS: 0
Acute Cyanide Poisoning Due To Ingestion of Apricot Seeds
(Soc Argentina Pediatria, 2024) Talay, Mehmet Nur; Orhan, Özhan; Orhan, Ozhan; Department of Internal Medical Sciences / Dahili Tıp Bilimleri Bölümü
[No Abstract Available]
Citation - WoS: 17
Citation - Scopus: 18
Acute Toxicity of Deltamethrin on the Fatty Acid Composition of Phospholipid Classes in Liver and Gill Tissues of Nile Tilapia
(Springer int Publ Ag, 2017) Kızmaz, Veysi; Bayar, A. S.; Kizmaz, V.; Bashan, M.; Satar, A.; Department of Medical Services and Techniques / Tıbbi Hizmetler ve Teknikleri Bölümü
Deltamethrin is a pyrethroid pesticide contaminating aquatic ecosystems. The purpose of this study was to clarify the acute toxicity of deltamethrin on the fatty acids of phospholipid (PL) classes in liver and gill of Nile tilapia. The fatty acids of PL classes were analyzed by gas chromatography. Deltamethrin brought about differences in the fatty acids of the PL classes in the liver and gill. In the liver of exposed fish, 16:0, 18:2(n-6), 22:6(n-3) in phosphatidylcholine (PC); 16:0, 18:1(n-9), 18:2(n-6), 20:4(n-6), 22:6(n-3) in phosphatidylethanolamine (PE); 16:0, 18:0, 18:1(n-9), 20:4(n-6), 22:6(n-3) in phosphatidylinositol (PI) and in phosphatidylserine (PS) 16:0, 18:1(n-9), 20:4(n-6), 22:6(n-3) were the affected fatty acids. There were significant alterations in Sigma MUFAs (monounsaturated fatty acids), a(n-3)PUFAs (polyunsaturated fatty acids) and Sigma(n-6)PUFAs in PC; Sigma SFAs (saturated fatty acids), Sigma MUFAs, Sigma PUFAs, Sigma(n-3)PUFAs and Sigma(n-6)PUFAs in PE; Sigma SFAs, Sigma MUFAs, Sigma(n-3)PUFAs and Sigma(n-6)PUFAs in PI and Sigma SFAs, Sigma MUFAs,Sigma PUFAs and Sigma(n-3)PUFAs in PS. In the gill, 18:2(n-6), 20:4(n-6), 22:6(n-3) in PC; 16:0, 18:1(n-9), 20:4(n-6), 22:6(n-3) in PE; 16:0, 18:0, 18:1(n-9), 18:2(n-6) in PI and in PS 16:0, 18:0,18:1(n-9), 20:3(n-6), 20:5(n-3), 22:6(n-3) affected. The alterations in Sigma SFAs, Sigma MUFAs, Sigma PUFAs and Sigma(n-6)PUFAs in PC; Sigma SFAs, Sigma MUFAs, Sigma PUFAs, Sigma(n-3)PUFAs and Sigma(n-6)PUFAs in PE; Sigma(n-3)PUFAs and Sigma(n-6)PUFAs in PI; Sigma SFAs, Sigma MUFAs, Sigma PUFAs, Sigma(n-3) PUFAs and Sigma(n-6)PUFAs in PS were significant in gill. The changes in the fatty acids of the PL classes in response to deltamethrin can influence structure and functions of the membrane systems. Changes in fatty acids may be one defense mechanism against the deltamethrin.
Citation - Scopus: 0
Adaptation of the Employee Spirituality Scale Into Turkish: a Study on Healthcare Workers
(Halil Eksi, 2025) Apak, Hıdır; Department of Social Services/ Sosyal Hizmet Bölümü
This study aimed to adapt the Employee Spirituality Scale to Turkish culture for healthcare professionals. A total of 230 healthcare workers participated in the adaptation of the scale, which comprises 24 items. The research data were collected face-to-face with a questionnaire that included demographic characteristics, the Employee Spirituality Scale, and the Spiritual Orientation Scale. Construct validity was analyzed using exploratory and confirmatory factor analyses. The two-factor structure of the Employee Spirituality Scale was confirmed in the Turkish sample and showed acceptable fit values. Because of CFA, 2 items were removed from the scale because they did not fit. For criterion validity, the Pearson Correlation Coefficient between the scale and the Spiritual Orientation Scale was calculated, and a significant positive result was obtained. This study demonstrated that the Turkish version of the Employee Spirituality Scale is a valid and reliable measurement tool for health care workers to assess the various dimensions of human spirituality that give individuals a sense of guidance, facilitate finding meaning and purpose in one’s tasks, enable them to overcome their weaknesses and limitations in the workplace, and assess various dimensions of human spirituality as a relationship with a higher power. © 2025 by Author(s).
Citation - WoS: 0
Citation - Scopus: 0
Adaptation of the Vicarious Resilience Scale To Turkish: a Validity and Reliability Study
(American Psychological Association, 2025) İşıker Bedir, Deniz; Boz, C.; Şeneldir-Patolo, A.; Kitapçıoğlu, S.; Işıker-Bedir, D.; Sanyar, S.; Department of Psychology / Psikoloji Bölümü
Objective: The 27-item Vicarious Resilience Scale (VRS) is the first tool developed to measure vicarious resilience in mental health professionals working with trauma survivors. Given that the VRS measures the positive impact on therapists resulting from observing the healing process of trauma victims, it is especially significant to evaluate its validity and reliability in Turkish culture. This study aims to adapt the VRS to Turkish and examine its psychometric properties. Method: VRS was adapted and administered via electronic survey to 337 mental health professionals from around the globe working with survivors of severe traumas, such as earthquake survivors. The validity of the VRS was examined using different techniques: confirmatory factor analysis (CFA) and criterion-related validity. Results: CFA yielded seven factors that were consistent with the original form: changes in life goals and perspective, client-inspired hope, increased recognition of clients’ spirituality as a therapeutic resource, increased capacity for resourcefulness, increased self-awareness and self-care practices, increased consciousness of power and privilege relative to clients’ social location, and increased capacity for remaining present while listening to trauma narratives. The Cronbach’s α reliability of the VRS was found to be.95; it displayed positive correlations with posttraumatic growth, psychological resilience, and quality of life, indicating convergent validity. However, it had a negative correlation with depression, anxiety, and stress, indicating discriminant validity. Conclusion: The VRS is a valid and reliable measurement scale by professionals working with trauma survivors to aid the recognition and cultivation of vicarious resilience in Turkish mental health professionals. © 2025 American Psychological Association
Adm and Sflt-1 Expression in Placentas With Gestational Diabetes Mellitus
(2023) Şeker, Uğur; Aşır, Fırat; Deveci, Engin; Arslan, Necat; Kaplan, Özge; Şeker, Uğur; Başaran, Süreyya Özdemir; Department of Basic Medical Sciences / Temel Tıp Bilimleri Bölümü
Amaç: Bu çalışmada gestasyonel diyabetes mellitusta (GDM) vasküler regülasyonda rolü saptanan iki yeni protein olan Adrenomedullin (ADM) ve soluble fms-benzeri tirozin kinaz (sFlt-1)’in ekspresyon seviyelerini incelemeyi, hastalığın histopatolojisinde bu proteinlerin ekspresyon seviyelerini karşılaştırmayı ve bu proteinlerin ekspresyon yoğunluğunun hastalıkla korelasyonunu gözlemlemeyi amaçladık. Gereç ve Yöntem: Çalışmamızda 20 Normotansif ve 20 GDM’li plasenta örneği alındı. Histolojik takip yöntemiyle takip edildi. Bu dokulardan 5µm kalınlığında kesitler alınarak Hematoksilen-Eozin, Periodic Acid Schiff (PAS) boyamaları yapıldı. İmmunünohistokimyasal olarak ADM ve sFlt-1 antikorları çalışıldı. Bulgular: GDM grubunda; kök villuslarındaki kan damarlarında dilatasyon ve konjesyon, endotel hücrelerinde hiperplazi görüldü. Villusların dış kısmındaki sinsitiyal köprülerde artış, mononükleer hücre infiltrasyonu, maternal bölgedeki desidual hücrelerin bazılarında piknotik nükleuslar ve sitoplazma kaybı izlendi. İmmunohistokimyasal incelemede villusların sitotrofoblast ve sinsitiyotrofoblast hücrelerinde ve sinsitiyal düğümlerde negatif ADM ekspresyonu vardı. Küçük villusların bazı sitotrofoblast hücrelerinde, damar endotel hücrelerinde ve desidual hücrelerde pozitif ADM ekspresyonu görüldü. GDM grubunda sFlt-1 ekspresyonu endotel hücrelerinde, mezenşimal bağ doku içindeki bazı Hofbauer hücrelerinde, desidual hücre nükleuslarında ve membranlarında pozitif olarak gözlendi. Sonuç: Desidual hücre membranlarında, sitotrofoblastlarda ADM pozitif ekspresyon gösterdiğinden ADM’nin glikoz yoğunluğunun belirlenmesinde ve bununla ilişkili olarak insülin regülasyonunda önemli bir düzenleyici olabileceğini düşündürmüştür. Yine sFlt-1’in maternal ve fötal bölgelerdeki endotel hücresi üzerindeki etkileri ve Hofbauer hücrelerindeki ekspresyonu, anjiyogenik etkide bu molekülün anahtar rol alabileceği kanısını uyandırmıştır.
Citation - WoS: 49
Citation - Scopus: 46
Adolescent Transport and Unintentional Injuries: a Systematic Analysis Using the Global Burden of Disease Study 2019
(Elsevier Sci Ltd, 2022) Peden, Amy E.; Cullen, Patricia; Francis, Kate Louise; Moeller, Holger; Peden, Margaret M.; Ye, Pengpeng; Ivers, Rebecca Q.
Background Globally, transport and unintentional injuries persist as leading preventable causes of mortality and morbidity for adolescents. We sought to report comprehensive trends in injury-related mortality and morbidity for adolescents aged 10-24 years during the past three decades. Methods Using the Global Burden of Disease, Injuries, and Risk Factors 2019 Study, we analysed mortality and disability-adjusted life-years (DALYs) attributed to transport and unintentional injuries for adolescents in 204 countries. Burden is reported in absolute numbers and age-standardised rates per 100 000 population by sex, age group (10-14, 15-19, and 20-24 years), and sociodemographic index (SDI) with 95% uncertainty intervals (UIs). We report percentage changes in deaths and DALYs between 1990 and 2019. Findings In 2019, 369 061 deaths (of which 214337 [58%] were transport related) and 31.1 million DALYs (of which 16.2 million [52%] were transport related) among adolescents aged 10-24 years were caused by transport and unintentional injuries combined. If compared with other causes, transport and unintentional injuries combined accounted for 25% of deaths and 14% of DALYs in 2019, and showed little improvement from 1990 when such injuries accounted for 26% of adolescent deaths and 17% of adolescent DALYs. Throughout adolescence, transport and unintentional injury fatality rates increased by age group. The unintentional injury burden was higher among males than females for all injury types, except for injuries related to fire, heat, and hot substances, or to adverse effects of medical treatment. From 1990 to 2019, global mortality rates declined by 34.4% (from 17.5 to 11.5 per 100 000) for transport injuries, and by 47.7% (from 15.9 to 8.3 per 100000) for unintentional injuries. However, in low-SDI nations the absolute number of deaths increased (by 80.5% to 42 774 for transport injuries and by 39.4% to 31 961 for unintentional injuries). In the high-SDI quintile in 2010-19, the rate per 100 000 of transport injury DALYs was reduced by 16.7%, from 838 in 2010 to 699 in 2019. This was a substantially slower pace of reduction compared with the 48.5% reduction between 1990 and 2010, from 1626 per 100 000 in 1990 to 838 per 100 000 in 2010. Between 2010 and 2019, the rate of unintentional injury DALYs per 100 000 also remained largely unchanged in high-SDI countries (555 in 2010 vs 554 in 2019; 0.2% reduction). The number and rate of adolescent deaths and DALYs owing to environmental heat and cold exposure increased for the high-SDI quintile during 2010-19. Interpretation As other causes of mortality are addressed, inadequate progress in reducing transport and unintentional injury mortality as a proportion of adolescent deaths becomes apparent. The relative shift in the burden of injury from high-SDI countries to low and low-middle-SDI countries necessitates focused action, including global donor, government, and industry investment in injury prevention. The persisting burden of DALYs related to transport and unintentional injuries indicates a need to prioritise innovative measures for the primary prevention of adolescent injury. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd.

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