Scopus İndeksli Yayınlar Koleksiyonu
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Article Citation - Scopus: 3A Rare Cause of Dysphagia: A Giant Ganglioneuroma in Parapharyngeal Space(Springer, 2022) Aslan, Mehmet; Dogukan, Fatih MertParafarengeal ganglioneuroma is a very rare benign tumor originating from the sympathetic nervous system that produces mass and functional effects. Ganglioneuroma is most commonly caused by the posterior mediastinal, retroperitoneal area and adrenal glands. Generally, they do not present any additional signs or symptoms other than mass. Horner’s syndrome may sometimes occur due to the compression of the sympathetic chain. A 41-year-old male patient with a long-standing mass in the lateral compartment of the left neck was admitted to our clinic. The patient was operated, and the pathological result of the mass was reported as ganglioneuroma. We present a rare case of ganglioneuroma in paraphryngeal space by reviewing the current literature. © 2022 Elsevier B.V., All rights reserved.Article Citation - Scopus: 4A Rare Cause of Dysphagia: Giant Lipoma in Parapharyngeal Space(Lippincott Williams and Wilkins, 2020) Aslan, Mehmet; Ozer Ozturk, Ebru; Dogukan, Fatih MertBackground: Parapharyngeal area is one of the most complex areas of head and neck anatomy. Tumors of the parapharyngeal region are very rare among head and neck tumors. Lipomas also constitute a tiny proportion of parapharyngeal tumors so parapharyngeal area lipomas are very rare in the literature. Due to anatomical location, these tumors treatment is challenging. Clinical Report: A 20-year-old male patient admitted to our department with complaints of swallowing difficulty and a mass on the right side of the neck. Magnetic resonance imaging was performed, and it was reported as a 6 4.5 cm lipoma. He underwent excision of parapharyngeal area lipoma by a transoral approach. Conclusion: Parapharyngeal lipomas are very rare, and difficult to diagnose before they turn out symptomatic. The primary treatment approach in tumors of the parapharyngeal area is surgery and the surgical approach should be chosen according to the anatomical location of the lesion. © 2021 Elsevier B.V., All rights reserved.Article Ability of Cha2ds2-vasc/R2cha2ds2-vasc Scores To Predict Complications Related To Cardiac Implantable Electronic Devices(Wiley, 2025) Aktan, Adem; Kilic, Raif; Guzel, Hamdullah; Tastan, Ercan; Oksul, Metin; Guzel, Tuncay; Soner, SerdarBackgroundGlobally, the number of cardiac implantable electronic devices (CIEDs) is increasing. In our study, we aimed to investigate whether CHA(2)DS(2)-VASc and R(2)CHA(2)DS(2)-VASc scores are predictive of CIED-related complications. MethodsOur investigation was carried out with a multicenter retrospective design. Patients who underwent CIED surgery at two cardiac centers in Turkey between January 2011 and May 2023, 1676, were evaluated. The patients were divided into two groups according to their R(2)CHA(2)DS(2)-VASc scores. Patients with R(2)CHA(2)DS(2)-VASc >= 5 were included in group 1 (380 patients), and patients with R(2)CHA(2)DS(2)-VASc < 5 (1296 patients) were included in group 2. The primary outcome was defined as the cumulative events. Each component of cumulative events, such as hematoma, pericardial effusion, pneumothorax, and infection, was also defined as a secondary outcome. ResultsThe study's patient population had an average age of 62.9 +/- 14 years. Pneumothorax (1.8% vs. 1.3%, p = 0.444), pericardial effusion or tamponade (0.35% vs. 0.2%, p = 0.659), and clinically significant hematoma (1.1% vs. 0.6%, p = 0.376) were comparable between the groups. Infection-related devices and cumulative events classified as primary outcomes were higher in the R(2)CHA(2)DS(2)-VASc >= 5 group (6.1% vs. 1.2%, p < 0.001; 7.6% vs. 3.2%, p < 0.001, respectively). Modeling analyses showed that the CHA(2)DS(2)-VASc score and HT were also independent predictors of device-related infection and cumulative events. ConclusionIn the R(2)CHA(2)DS(2)-VASc >= 5 groups, infection related to the device system and cumulative events were higher. Patients with an R(2)CHA(2)DS(2)-VASc score of 5 or more and a high CHA(2)DS(2)-VASc score should be evaluated more carefully regarding infection and cumulative events before and after the operation.Article Acute Cyanide Intoxication Due To Apricot Seed Ingestion(Soc Argentina Pediatria, 2024) Talay, Mehmet N.; Gungor, Emre; Orhan, OzhanIntroduction : Cyanide poisoning, whether it be accidental or intentional, remains a significant danger to adults and children, especially in societies where agriculture is a primary source of income. We examined the clinical follow-up, complications, and results of cyanide poisoning cases that occurred after eating the pits and seeds of plants containing cyanide glycosides, such as apricot kernels and almonds. Methods : Between 01/01/2017 and 01/08/2022, 14 children aged 1-18 years who were followed up with a prediagnosis of cyanide poisoning in our Paediatric Intensive Care Unit (PICU) were retrospectively analysed. Results : Eight of the patients followed with a preliminary diagnosis of cyanide poisoning were female and six were male. The most common admission month was July (42.8%) coinciding with the agricultural season. The most common symptoms at presentation were weakness and fatigue (n = 7). In the PICU, 4 patients presented lip cyanosis; 3, altered level of consciousness. Vomiting, seizure, headache, dizziness and palpitatons were less frequent. Four patients were treated with hydroxocobalamin (Cyanokit (R) ) as an antidote due to acidosis in their blood gases. All patients treated for cyanide poisoning were discharged. Conclusions : Cyanide poisoning should be considered in paediatric patients with suspicious findings, sudden loss of consciousness, increased anion gap acidosis and lactic acidosis. The history of eating the seeds of plants such as apricot and almonds should be investigated .Article Citation - WoS: 6Citation - Scopus: 9Adaptions in subsistence strategy to environment changes across the Younger Dryas-Early Holocene boundary at Kortiktepe, Southeastern Turkey(Sage Journals, 2022) Emra, Stephanie; Benz, Marion; Sıddıq, Abu Bakar; Özkaya, VecihiThe site of Körtiktepe in southeastern Turkey is one of few sites in the Upper Mesopotamia basin that attests continuous, permanent occupation across the boundary from end of the colder, drier Younger Dryas (YD) into the comparatively wetter and warmer Early Holocene (EH). This allows for the study of the degree of environmental change experienced on a local level over this boundary as well as for the study of the adaptations that the occupants of the site undertook in response to these changes. The mammal assemblage of Körtiktepe remains relatively stable across the YD – EH transition with the main contributors to diet being mouflon (Ovis orientalis) and red deer (Cervus elaphus) in approximately the same quantities, although the contribution of aurochs (Bos primigenius) increases in the EH. The most significant changes can be seen in the shift in avifauna remains, with a sharp increase of waterbirds during the EH. It is proposed that these shifts reflect changes in the local environment with an increase in woodland cover as well as expansion of local waterways, which is generally consistent with previously published archaeobotanical studies. In terms of species exploited, mortality profiles as well as size distribution of mammals, a great deal of continuity is observed. This suggests that over this particular period the local impact of the beginning of the Early Holocene was not overly dramatic, allowing for cultural continuity of previously established subsistence strategies.Article Citation - WoS: 19Citation - Scopus: 20The Adsorption and Inhibition Efficiency of 2-Amino for Corrosion of Mild Steel in Hydrochloric Acid Solution(Emerald Group Publishing Ltd, 2023) Okten, Veysi; Yildiz, Resit; Sigircik, GoekmenPurposeThis study aims to prevent mild steel (MS) against corrosion in 0.5 M HCl solution, 2-amino-4-methoxy-6-methyl-1,3,5-triazine was used. The effectiveness of the compound as a corrosion inhibitor was studied via electrochemical, surface and theoretical calculation techniques. Design/methodology/approachFor concentrations ranging from 0.5 to 10.0 mM, almost similar polarization resistances were obtained from electrochemical impedance spectroscopy (EIS) and linear polarization resistance tests. It also investigated inhibitive activity of 2-amino-4-methoxy-6-methyl-1,3,5-triazine on the steel surface using scanning electron and atomic force microscope instruments. Langmuir adsorption is the best matched isotherm for the adsorption of the inhibitor to the steel surface. FindingsEIS method was used to determine inhibition efficiency, which was determined to be 95.7% for 10.0 mM inhibitor containing acid solution. Density functional theory's predictions for quantum chemistry agreed well with the other experimental results. Originality/valueThe methods used in this study are effective and applicable; the used organic inhibitor is 2-amino-4-methoxy-6-methyl-1,3,5-triazine; and protective effectiveness is important, which is crucial for the task of MS corrosion prevention.Article Citation - WoS: 14Citation - Scopus: 13Adsorption of nickel(II) ions from aqueous solutions using Malatya clay: Equilibrium, kinetic, and thermodynamic studies(Environmental Progress & Sustainable Energy, 2023) Baran, Ayşe; Dal, Mehmet Can; Onursal, Nilgün; Altunkaynak, YalçınThis paper evaluates Malatya clay (MC) for the removal of Ni(II) ions from aqueous solutions. For adsorption efficiency, the impacts of several factors, such as pH, starting metal ion concentration, and contact duration, were examined. The optimal initial Ni(II) ion concentration was determined to be 5 mg/L, the adsorption contact duration was 360 min, and the solution's pH was 6.27. Using scanning electron microscopy, energy dispersive spectroscopy, and Fourier transform infrared spectroscopy, the surface characteristics of Malatya clay were examined. The isotherm data fit the Langmuir isotherm model, indicating chemical adsorption and likely irreversibility of the process, according to the results. At 298, 308, and 318 K, the adsorption capacities of Ni(II) were determined to be 10.267, 11.834, and 12.285 mg/g, respectively. Adsorption kinetic data revealed that the adsorption of Ni(II) metal ions followed the pseudosecond-order kinetic model. According to thermodynamic studies, Ni(II) ion adsorption on the MC is spontaneous and endothermic. MC has proven to be an effective and alternative material for the removal of Ni(II) ions from aqueous media due to its excellent removal ability, availability, and low cost, as well as its features such as being able to be used without any chemical treatment and being environmentally friendly.Article Citation - WoS: 22Citation - Scopus: 22Aflatoxin M1 in Human Breast Milk in Southeastern Turkey(Springer Heidelberg, 2017) Altun, Serap Kilic; Gurbuz, Semra; Ayag, EminThis study was performed to determine aflatoxin M-1 (AFM(1)) in human breast milk samples collected in AanlA +/- urfa, located in Southeastern region of Turkey, and to investigate a possible correlation between AFM(1) occurrence (frequency and levels) and sampling seasons. Human breast milk samples collected in December 2014 and in June 2015 from a total of 74 nursing women, both outpatient and inpatient volunteers in hospitals located in AanlA +/- urfa, Turkey, were analyzed using competitive enzyme-linked immunosorbent assay (ELISA) for the presence of AFM(1). AFM(1) was detected in 66 (89.2%) out of 74 samples at an average concentration of 19.0 +/- 13.0 ng/l (min.-max., 9.6-80 ng/l). There was a statistically significant difference between December and June concerning AFM(1) levels (p < 0.05). Further detailed studies will be needed to determine the main sources of aflatoxins in food, to establish protection strategies against maternal and infant exposure to these mycotoxins.Article Citation - WoS: 7Citation - Scopus: 8Air Quality Forecasting Using Machine Learning: Comparative Analysis and Ensemble Strategies for Enhanced Prediction(Springer Int Publ Ag, 2025) Ozupak, Yildirim; Alpsalaz, Feyyaz; Aslan, EmrahAir pollution poses a critical challenge to environmental sustainability, public health, and urban planning. Accurate air quality prediction is essential for devising effective management strategies and early warning systems. This study utilized a dataset comprising hourly measurements of pollutants such as PM2.5, NOx, CO, and benzene, sourced from five metal oxide sensors and a certified analyzer in a polluted urban area, totaling 9,357 records collected over one year (March 2004-February 2005) from the Kaggle Air Quality Data Set. A comprehensive comparison of ten machine learning regression models XGBoost, LightGBM, Random Forest, Gradient Boosting, CatBoost, Support Vector Regression (SVR) with Bayesian Optimization, Decision Tree, K-Nearest Neighbors (KNN), Elastic Net, and Bayesian Ridge was conducted. Model performance was enhanced through Bayesian optimization and randomized cross-validation, with stacking employed to leverage the strengths of base models. Experimental results showed that hyperparameter optimization and ensemble strategies significantly improved accuracy, with the SVR model optimized via Bayesian optimization achieving the highest performance: an R2 score of 99.94%, MAE of 0.0120, and MSE of 0.0005. These findings underscore the methodology's efficacy in precisely capturing the spatial and temporal dynamics of air pollution.Article Citation - WoS: 1Citation - Scopus: 1The Ameliorative Effects of Hesperidin in Rats Developed Hepatotoxicity With Deltamethrin(Mashhad Univ Med Sciences, 2025) Karabekir, Seda Cetinkaya; Sozen, Mehmet Enes; Ayan, Ilknur Cinar; Savas, Hasan Basri; Cuce, Gokhan; Kalkan, SerpilObjective(s): Deltamethrin (DLM) is a widely used insecticide in agriculture; however, exposure to it can lead to serious health problems. This study aimed to evaluate the protective effects of hesperidin (HSP), a natural antioxidant, against DLM-induced liver toxicity. Materials and Methods: Thirty-two male Wistar Albino rats (250-300 g, 4 months old) were divided into four groups. The control group received 1 ml of corn oil via oral gavage for 30 days. The DLM group received 1.28 mg/kg DLM in corn oil for 30 days. The DLM+HSP 100 mg/kg and DLM+HSP 300 mg/kg groups received 1.28 mg/kg DLM followed by 100 mg/kg or 300 mg/kg HSP in distilled water, respectively, 30 min after DLM administration for 30 days. Liver tissues were examined histopathologically. Masson's trichrome staining and PCR assessed fibrosis. Caspase 3 and 9 expressions in liver tissues were determined by immunohistochemistry and PCR. Biochemical analyses were conducted on serum samples. Results: HSP supplementation led to a dose-dependent decrease in aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels. DLM exposure decreased antioxidant capacity, while HSP supplementation increased it dose-dependently. Histopathological evaluations showed increased liver damage in the DLM group, while HSP administration reduced liver toxicity. Masson's trichrome staining and analysis of collagen I (COL1A1) and collagen III (COL3A1) gene expression revealed increased fibrosis in the DLM group, which was attenuated with HSP treatment. Conclusion: The potential prevention of DLM-induced liver toxicity and apoptosis by HSP may be an alternative protective strategy.Article Citation - WoS: 7Citation - Scopus: 7Analysis of bioactive compounds using LC-ESI-MS/MS, cytotoxic, antimicrobial effects, and enzyme activities from Cyclotrichium origanifolium(Wiley Online Library, 2022) Aktepe, Necmettin; Baran, Ayşe; Atalar, Mehmet Nuri; Baran, Mehmet Fırat; Keskin, Cumali; Taşkin, Abdullah; Yavuz, Ömer; Demirtaş, İbrahim; Oğuz, Ercan; Jahan, IsratCyclotrichium origanifolium is a medicinal plant belonging to the Lamiaceae family. In this study, phenolic content analysis, antimicrobial effects, and cytotoxic effects of extracts of C. origanifolium were investigated. In the extracts, phenolic compound analysis by the liquid chromatography–electrospray ionization– tandem mass spectrometry method, antimicrobial effect by the minimum inhibition concentration method, and cytotoxic effect on human dermal fibroblasts (HDF), glioblastoma cell (U87), ovarian adenocarcinoma cell (Skov-3), and human colorectal adenocarcinoma cell (CaCo-2) cancer cell lines were investigated. Cytotoxicity analyses were performed by the MTT method. In addition, the GST and AChE enzyme activities of the extracts were also measured. Around 18 compounds were detected in both the methanol and ethanol extract. It was found that the best antimicrobial effect on Gram-negative Pseudomonas aeruginosa was on methanol extract, while the ethanol extract was on Candida albicans fungus (respectively, 2.50mg/ml, 5.0 μg/ml). A 500μg/ml of methanol extract has been shown to have cytotoxic activity high effect on HDF cells. GST and AChE activity were found to decrease in a concentration-dependent manner.Article Citation - WoS: 2Citation - Scopus: 2Analysis of Lipid Classes and the Fatty Acid Composition of Fresh and the Salted Fish, Alburnus Tarichi(Taylor & Francis Ltd, 2022) Kizmaz, VeysiThis study was carried out to determine the distribution of total, phospholipid and triacylglycerol fatty acid composition in salted and fresh fish of pearl mullet. Fatty acid analyses were performed in muscle tissues of the fish samples. Eicosapentaenoic acid (EPA), Docosahexaenoic acid (DHA), Omega-3 (n-3), Omega-6 (n-6) which are important for health, were determined in the analyses. The distribution of total and TAG fatty acids in males and females was similar. It was determined that the changes were in the Phospholipid. N-3/n-6 ratio showed a similar distribution in both female and male individuals. In particular, the results obtained may benefit the fisheries industry, nutritionists and researchers, as the nutritional value of the fish is high.Article Citation - WoS: 23Citation - Scopus: 31Analysis of Promising Barley (Hordeum Vulgare L.) Lines Performance by AMMI and GGE Biplot in Multiple Traits and Environment(Aloki Applied Ecological Research and Forensic Inst Ltd, 2019) Tekdal, S.; Dogan, S.; Kendal, E.; Karaman, M.The development of stable and adaptable new cultivars are based only on positive results obtained from the interaction between the genotype and the environment. Therefore, the study aimed to test the stability and general adaptability of promising barley lines in terms of grain yield and traits in multi -environments. For this purpose, twelve barley genotypes were used in the study. The trials were carried out with four replications in a random design at seven environments in years 2012-13 and 2013-14. The superior and stable genotypes were identified with GGE biplot and AMMI (Additive main effects and multiplicative interaction) models. The AMMI analysis showed that the major treatment sum of squares was affected by environments (80.6%), GE (14.0%) and genotypes (5.4%), respectively. On the other hand, the first two principal component axes (PCA 1 and PCA 2) contributed to the complete interaction with 88.1%, whereas, PCA 3 and PCA 4 axes only with 12.0%. The GGE biplot indicated that G4 is adaptable for all environments, while Altikat, G2 and G3 showed specific adaptation to El, E3 and E5, G6, G7 and G8 to E6, respectively. According to both techniques, G2, G3, G6, G7, G8 and Altikat were the best genotypes with high yield, whereas G4 was the best with high yield, and stable and general adaptation. The results of biplot indicated that G4 (ARUPO /K8755//MORA/3/CERISE/SHYRIHALEL I/4/CANELA/5/HART-BAR) was recommended for release and it was released as HEVSEL in 2017. On the other hand; G7 and G6 were protected as genetic material to use as parent in breeding programs for yield stability and quality respectively.Article Analysis of Pyrolysis Liquid From Green Walnut Shells (Juglans Regia L.) and Its Antifungal Activity Against Pathogenic Fungi in Ornamental Plants(Corvinus University of Budapest, 2025) Koç, İ.Pathogenic fungi damage ornamental plant production in both quality and quantity. Organic fungicides are significantly needed for the control of these pathogens. This study was carried out to analyze the content of pyrolysis liquid (PL) obtained from green walnut shells (Juglans regia L.) and to evaluate its antifungal activity against Fusarium oxysporum and Verticillium dahliae. This research was carried out under in vitro conditions with 5%, 10%, 15%, 20% and 25% (v/v) PL solution applications in a Randomized Plot Design with four replications. The Poisoned Food Method was used to determine the antifungal activity of PL. As a result of chemical content analysis of PL, 53 components were detected by GC-MC, and the major components were propanoic acid, 2-hydroxy-(CAS) (21.69%), e-2-undecenal (7.11%), and nonanal (5.76%). Twelve components were detected by LC-MS/MS, with vanillic acid (393.28 µg/L), vanillin (334.34 µg/L), and syringic acid (222.80 µg/L) identified as the major components. Total phenolic content (201.76 ± 12.50 mg GAE/mL) and total flavonoid content (114.74 ± 4.50 mg QE/mL) were determined. Therefore, the effect of concentration on colony size varied depending on the species. It was determined that PL showed stronger antifungal activity at higher concentrations, with the highest activity observed at the 25% (v/v) solution. © 2025, ALÖKI Kft., Budapest, Hungary.Article Anason (Pimpinella anisum L.) ve kimyon (Cuminum cyminum L.) tohumlarının uçucu yağ kompozisyonu ile antimikrobiyal ve antioksidan özelliklerinin belirlenmesi(2014) Haşimi, Nesrin; Tolan, Veysel; Kızıl, Süleyman; Kılınç, ErsinBu çalışmada, anason (Pimpinella anisum L.) ve kimyon (Cuminum cyminum L.) tohumlarının uçucu yağ bileşenleri ile bu yağların antimikrobiyal ve antioksidan özelliklerinin belirlenmesi amaçlanmıştır. Uçucu yağ bileşenleri GC/MS cihazı ile belirlenmiştir. Yağların antimikrobiyal özellikleri disk difüzyon yöntemi ile Gram pozitif (Staphylococcus aureus ATCC 25923, Streptococcus pyogenes ATCC 19615), Gram negatif (Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853) bakterileri ve maya (Candida albicans ATCC 10231) kullanılarak, antioksidan özellikler ise DPPH yöntemiyle belirlenmiştir. Anason uçucu yağının esas bileşeninin trans-anetol (% 52.94) olduğu, bunu iso-anetol (% 13.89), karyofillen oksit (% 8.55) ve karyofillen (% 4.29)’in izlediği; kimyon uçucu yağının ise sırası ile ?-pinen (% 15.77), ?- terpinen (% 15.52), 1-fenil-1-butanol (% 15.13) ve kuminik aldehit (% 12.74) içerdiği saptanmıştır. Anason uçucu yağının mikroorganizmalar üzerinde düşük, kimyon uçucu yağının ise orta derecede antimikrobiyal aktivite gösterdiği saptanmıştır. Kimyon uçucu yağı C. albicans’a karşı 22±0.9 mm’lik inhibisyon zon çapı ile yüksek antimikrobiyal aktivite göstermiştir. P. aeruginosa her iki uçucu yağa karşı direnç göstermiştir. Kimyon uçucu yağının antioksidan aktivitesi (% 75.60) askorbik asit aktivitesine (% 78.75) yakın, BHA (% 50.45) ve BHT (% 23.54) aktivitesinden daha yüksek bulunmuştur. Anason düşük antioksidan aktivite (% 23.24) göstermiş olmasına rağmen BHT ile benzer aktivite göstermiştir. Çalışmada kullanılan örneklerin aktivite sıralaması askorbik asit>kimyon>BHA>BHT>anason şeklinde gerçekleşmiştir.Article Citation - WoS: 4Citation - Scopus: 4Animal Remains of Alaybeyi Hoyuk(Tubitak Scientific & Technological Research Council Turkey, 2019) Siddiq, Abu BakarThis paper presents the zooarchaeological observations on animal remains of Alaybeyi Hoyuk unearthed from 2016 and 2017 excavation sessions. Dated to 4721-4553 cal. BC, Alaybeyi stands so far as the oldest archaeological settlement discovered in northeast Anatolia. Therefore, the faunal assemblage at Alaybeyi offers great opportunity to study the status of animals and their relationships with humans in the largely unexplored Kars-Erzurum plateau covering a period from the Chalcolithic to Late Iron Age. Taxonomic and osteometric analyses show that, like the present day, cattle were dominant over caprines, revealing extensive cattle pastoralism in the region for at least about 7 millennia. While caprines too were significant in the subsistence strategy of local humans, there was not any sign of raising pigs. Significant numbers of wild species including carnivores, aquatic mammals, and rodents, as well as resident and migratory birds, were also hunted by Alaybeyi people. Additionally, horse burials, horse cult, dog burials, and a rich number of dog bones present animals as versatile actors in various ritual and symbolic practices at the site.Article Citation - Scopus: 1Ankara huseyin gazi tomb in the context of mountain, water, and cave cults;(Gazi Universitesi, Turk Kulturu ve Haci Bektas Veli, 2017) Akyüz, Ç.Mountain is believed to keep the earth "stand straight" and conceived as a space of God to carve out the highest point of the earth. They shape traditional practices and social life as a cult in the old Turkish belief system. It contains rushing rivers, the springs and the sources of rivers. Water is the source of the material and spiritual life and it is considered to be sacred. In this regard, it can be said that many sacred narrative formed around the mountains and the water. Mountain and cave are also contemplation places for divine personality. Huseyin Gazi, one of the saints in Anatolia, who is believed to live in Mamak, Ankara, there is a mountain and a tomb by his name and stories associated with his sacred personality. Water metaphor is also noteworthy in a dialectical interaction with both mountain and Huseyin Gazi is blessed in this stories. In this regard, such stories refer naming the places in the context of the sacred mountain and cave metaphores and providing information about the origin of water resources in the context of the metaphor of holy water. In this study, stories that talk about Huseyin Gazi are handled in the context of mountain, water, and cave cults by analyzing printed materials and interviewing people. The issues of evolvement of historical personalities into phenomenon and mythical place names are also studied.Within this faremework in the foregoing verbal data about Huseyin Gazi indicates that his holy personality passes ahead of his historical personality.Article Citation - WoS: 7Citation - Scopus: 10Antecedents of Gastronomy Destination Brand Equity: an Examination of Gastronomy Experience, Motivation, and Destination Satisfaction(Akdeniz Univ, Tourism Fac, 2023) Kodas, Davut; Ozel, cagil HaleThis paper aims to test the relationships among gastronomic experience, motivation, destination satisfaction, and gastronomy destination brand equity. Data (n:600) was gathered from domestic visitors visiting Gaziantep in March, April to May 2018. Scale development to measure gastronomy experiences and scale adaptation process of destination brand equity were carried out. The relationships among the variables were examined with structural equation modeling. According to the findings, except H5 and H8, all hypotheses are significant in the research model. At the end of the study, significant theoretical and managerial implications were provided for the tourism providers and destination marketers, and managers.Article Antifungal Activity of Endophytic Bacillus Spp. Bacteria and Its Effect on Root and Coleoptile Length During Germination Period(Centenary University, 2025) Güney, İnci GülerIn this study, endophytic bacteria were isolated from roots and crowns of rosemary (Rosmarinus officinalis L.), olive (Olea europaea L.), and loquat (Eriobotrya japonica L.) plant samples. The morphological and physiological properties of nine isolated endophytic bacteria were determined. All isolates were identified as Gram-positive, oxidase-positive and catalase-positive. Amylase, cellulase, and carbohydrate tests gave positive results. Antagonistic activities of the isolates against fungal pathogens varied between 85.7% and 52.9% against Fusarium culmorum and between 86.0% and 65.1% against Neoscytalidium dimidiatum. BMBA2 isolate gave the best results both in Petri dish antagonistic activity and in wheat seed germination in terms of root length and coleoptile length. BMBA2 isolates gave the best results with a coleoptile length of 7.58 cm and root length of 8.33 cm. In wheat seeds treated with F. culmorum and bacteria, the BMBA2 isolate gave the best result with a coleoptile length of 6.98 and a root length of 7.30 cm. For the identification of bacteria, in vitro BiBA1 and ND3BA were determined as Bacillus amyloliquefaciens subsp. plantarum; BiBA2 and YDBA as Bacillus subtilis; NDBA, ND2BA, BMBA1, BMBA2, and BMBA3 as Bacillus mojavensis. Since this is the first study to use endophytic Bacillus mojavensis as a biological agent against F. culmorum and N. dimidiatum pathogens, the results obtained from this study are thought to be important and promising in terms of application.Article Citation - Scopus: 20Antioxidant, anticancer and anticholinesterase activities of flower, fruit and seed extracts of hypericum amblysepalum HOCHST(Asian Pacific Organization for Cancer Prevention, 2015) Keskin, CumaliBackground: Cancer is an unnatural type of tissue growth in which the cells exhibit unrestrained division, leading to a progressive increase in the number of dividing cells. It is now the second largest cause of death in the world. The present study concerned antioxidant, anticancer and anticholinesterase activities and protocatechuic, catechin, caffeic acid, syringic acid, p-coumaric acid and o-coumaric concentrations in methanol extracts of flowers, fruits and seeds of Hypericum amblysepalum. Materials and Methods: Antioxidant properties including free radical scavenging activity and reducing power, and amounts of total phenolic compounds were evaluated using different tests. Protocatechuic, catechin, caffeic acid, syringic acid, p-coumaric acid and o-coumaric concentrations in extracts were determined by HPLC. Cytotoxic effects were determined using the MTT test with human cervix cancer (HeLa) and rat kidney epithelium cell (NRK-52E) lines. Acetyl and butyrylcholinesterase inhibitory activities were measured by by Ellman method. Results: Total phenolic content of H. amblysepalum seeds was found to be higher than in fruit and flower extracts. DPPH free radical scavenging activity of the obtained extracts gave satisfactory results versus butylated hydroxyanisole and butylated hydroxytoluene as controls. Reducing power activity was linearly proportional to the studied concentration range: 10-500 µg/mL LC50 values for H. amblysepalum seeds were 11.7 and 2.86 respectively for HeLa and NRK-52E cell lines. Butyryl-cholinesterase inhibitory activity was 76.9 ± 0.41 for seed extract and higher than with other extracts. Conclusions: The present results suggested that H. amblysepalum could be a potential candidate anti-cancer drug for the treatment of human cervical cancer, and good source of natural antioxidants.
