Hemşirelik Bölümü Koleksiyonu
Permanent URI for this collectionhttps://hdl.handle.net/20.500.12514/222
Browse
Browsing Hemşirelik Bölümü Koleksiyonu by Scopus Q "Q4"
Now showing 1 - 7 of 7
- Results Per Page
- Sort Options
Article Citation - WoS: 5Citation - Scopus: 4Biosynthesis of AgNPs by extract from waste leaves of Citrullus lanatus sp. (watermelon); characterization, antibacterial and antifungal effects(Progress in Nutrition, 2021) Aktepe, Necmettin; Baran, AyşeSilver nanoparticles (AgNPs) are valuable materials with a large number of sectors used. Green synthesis is very important for biomedical applications as they show biocompatible properties. In this study, AgNPs were easily synthesized using the environmentally friendly green synthesis approach using agricultural waste parts of Citrullus lanatus sp. plant grown in Diyarbakır region. Characterization of synthesized AgNPs was made. Fourier Transform Infrared Spectroscopy (FTIR) analysis was used to evaluate the phytochemicals responsible for effective reduction in the formation of AgNPs. UV-visible spectrophotometer (UV-Vis.) Spectra were also used to determine the presence of AgNPs. X-Ray Diffraction Diffractometer (XRD), Scanning Electron Microscope (SEM), Transmission Electron Microscope, Zeta potential analyzes were performed to define the crystal structures, dimensions and surface charges of AgNPs, respectively. In these data, it was determined that AgNPs showed maximum absorbance at 460 nm, spherical appearance, 21.27 crystal nano size and -30.05 mV zeta potential. Antimicrobial effects of AgNPs on gram positive Staphylococcus aureus (S. aureus) and Bacillus subtilis (B. subtilis) bacteria, gram negative Escherichia coli (E. coli) and Pseudomonas aeruginosa (P. aeruginosa) bacteria, as well as on fungus C. albicans pathogenic microorganisms It was analyzed by specifying the Minimum Inhibition Concentration (MIC) by microdilution.Article Citation - WoS: 2ERUCA SATIVA MILL SEEDS OIL ALLEVIATES HYPERLIPIDEMIA AND NON-ALCOHOLIC FATTY LIVER DISEASE IN SYRIAN HAMSTER(2022) Alhilal, M; Sulaiman, Y A M; Subuh, A M; Habra, N; Alhilal, SThe impact of oils rich in long chain monounsaturated fatty acids (LCMUFA) against hyperlipidemia and non-alcoholic fatty liver disease (NAFLD) has been inadequately described. In addition, the chemical solvents and the high temperature used in vegetable oils extraction process from seeds cause severe loss of many vital compounds. So the goal of this paper was to examine the effect of cold pressed Eruca sativa Mill seeds oil (ESSO), as a source of LCMUFA, on hyperlipidemia and NAFLD in Syrian hamster. The ESSO content of fatty acids was analyzed using chromatographic methods. Fifty two (52) healthy male golden Syrian hamsters used in this experiment were randomly divided into 4 groups (Completely Randomized Design). Negative control group, CHD group, positive control group and ESSO group. This experiment was achieved in two periods. The first period continued 4 weeks, in which hyperlipidemia and NAFLD were induced in CHD, positive control and ESSO groups through feeding on a hyperlipidemic diet. The second period also lasted 4 weeks, in which ESSO was orally gavaged at 2 g/kg of the body weight daily to animals of ESSO group. The levels of total cholesterol (TC), triglycerides, HDL-C and glucose and the activities of ALT, AST, ALP, LDH and CK were analysed in the serum. One way analysis of variance (ANOVA) followed by Duncan's multiple range test was used for statistical analysis. The consumption of hyperlipidemic diet for 4 weeks caused a significant raise (P<0.05) of triglycerides, glucose, ALT, AST, LDH, CK and a significant reduction (P<0.05) of the HDL-C/TC ratio, at the same time created lipid accumulation in liver cells in CHD, positive control and ESSO groups in comparison with negative control group at the end of the first period. These negative influences were alleviated in ESSO group by administration of ESSO at the end of second period. In conclusion, The examined cold pressed ESSO has effective hypolipidemic and hepatoprotective effects in Syrian hamsters with hyperlipidemia and NAFLD.Article Citation - WoS: 2Citation - Scopus: 2ERUCA SATIVA MILL SEEDS OIL ALLEVIATES HYPERLIPIDEMIA AND NONALCOHOLIC FATTY LIVER DISEASE IN SYRIAN HAMSTER(Journal of Animal & Plant Sciences, 2022) Alhilal, M.; Sulaiman, Y.A.M.; Subuh, A.M.; Habra, N.; Alhilal, S.The impact of oils rich in long chain monounsaturated fatty acids (LCMUFA) against hyperlipidemia and non-alcoholic fatty liver disease (NAFLD) has been inadequately described. In addition, the chemical solvents and the high temperature used in vegetable oils extraction process from seeds cause severe loss of many vital compounds. So the goal of this paper was to examine the effect of cold pressed Eruca sativa Mill seeds oil (ESSO), as a source of LCMUFA, on hyperlipidemia and NAFLD in Syrian hamster. The ESSO content of fatty acids was analyzed using chromatographic methods. Fifty two (52) healthy male golden Syrian hamsters used in this experiment were randomly divided into 4 groups (Completely Randomized Design). Negative control group, CHD group, positive control group and ESSO group. This experiment was achieved in two periods. The first period continued 4 weeks, in which hyperlipidemia and NAFLD were induced in CHD, positive control and ESSO groups through feeding on a hyperlipidemic diet. The second period also lasted 4 weeks, in which ESSO was orally gavaged at 2 g/kg of the body weight daily to animals of ESSO group. The levels of total cholesterol (TC), triglycerides, HDL-C and glucose and the activities of ALT, AST, ALP, LDH and CK were analysed in the serum. One way analysis of variance (ANOVA) followed by Duncan's multiple range test was used for statistical analysis. The consumption of hyperlipidemic diet for 4 weeks caused a significant raise (P<0.05) of triglycerides, glucose, ALT, AST, LDH, CK and a significant reduction (P<0.05) of the HDL-C/TC ratio, at the same time created lipid accumulation in liver cells in CHD, positive control and ESSO groups in comparison with negative control group at the end of the first period. These negative influences were alleviated in ESSO group by administration of ESSO at the end of second period. In conclusion, The examined cold pressed ESSO has effective hypolipidemic and hepatoprotective effects in Syrian hamsters with hyperlipidemia and NAFLD.Article Citation - WoS: 1Citation - Scopus: 2Evaluation of the organizational innovation and self-efficiency levels of health workers(Acta Scientiarum. Health Sciences, 2023) Bayram Değer, Vasfiye; Vural Doğru, Birgül; Arslan, NurgülThe aim of this study was determine whether the personal features of the participants create a difference in terms of organizational innovation. This study was conducted with 1234 nurses and midwives. A multiple regression model was created to see and predict the effect on individuals' total innovative scores and self-efficacy scores. The total innovative and the self-efficacy score are predicted with multiple regression analyses. It was observed that the variable that most affected both the total innovative score and the self-efficacy score of the individuals was the education level of the individuals. The fact that midwives and nurses have a certain level of innovative and self-confidence is important for the society to receive better and faster health services. In this study, it was observed that the education level was important for the development of innovative and self-confidence in both groups.Article Citation - WoS: 13Citation - Scopus: 13Fast and Low-Cost Biosynthesis of AgNPs with Almond Leaves: Medical Applications with Biocompatible Structures(Progress in Nutrition, 2021) Aktepe, Necmettin; Baran, AyşeIn this study, silver nanoparticles (AgNPs) were obtained in a low cost, easy and simple way by using the leaf extract of Prunus dulcis L. (almond tree) growing in the Mardin region. Characterization of AgNPs obtained by biosynthesis: Fourier Transform Infrared Spectroscopy (FTIR), X-Ray Diffractometer (XRD), UV-visible spectrophotometer (UV-Vis.), Scanning Electron Microscope (SEM), Transmission Electron Microscope(TEM), Zeta potential and Zeta size analysis was done through data. It was determined that AgNPs have maximum absorbance at 443 nm wavelength, they exhibit 14.67 crystal nano size, -19.9 mV zeta potential in spherical appearance. The Minimum Inhibition Concentration (MIC) of the obtained AgNPs was determined by using microdilution method on the growth of pathogen strains.Article Hastanelerde Görevli Sağlık Çalışanlarının Bireysel İş Yükü Algıları(Sağlık ve Hemşirelik Yönetim Dergisi, 2018) Çiftçioğlu, Gülcan; Tunç, Gülistan; Güneş, Aynur; Değer, Vasfiye; Çifçi, SemaGİRİŞ: İş yükü bireysel açıdan işi yapmak için geçen zamanı ve enerjiyi, örgüt açısından verimliliği göstermektedir. İş yükü, çalışanlar ve örgütler bakımdan çok önemli bir değişkendir. AMAÇ: Bu araştırmanın amacı, bir devlet hastanesinde çalışan sağlık çalışanlarının çalışma ortamlarına ilişkin iş yükü algı düzeylerini ortaya koymaktır. YÖNTEM: Araştırmada veri toplama aracı olarak, sağlık çalışanlarının çalışma ortamlarına ilişkin algılarını belirlemeye yönelik “Bireysel İş Yükü Algı Ölçeği” ve “Kişisel Bilgi Formu” kullanılmıştır. Bu ölçek Cox tarafından 2003 yılında geliştirilmiş ve Cox ve arkadaşları tarafından 2006 yılında geçerlilik ve güvenirliği test edilmiştir. Saygılı tarafından 2008 yılında Türkçeye uyarlanmıştır. Araştırmanın evrenini araştırma izni alınabilen devlet hastanesinde görev yapan tüm sağlık personeli (421 kişi) oluştururken, örneklemini bu hastanede çalışan tüm sağlık çalışanlarından araştırmaya katılımda gönüllü olan 220 kişi oluşturmuştur. Yüz doksan beş sağlık çalışanından kullanılabilir veri toplanmıştır. Araştırmanın verileri Ekim- Kasım 2016 tarihleri arasında toplanmıştır. Araştırma verileri Istatistical Package for Social Science for Windows 16.0 programı kullanılarak sayı, yüzdelik ve ortalama-standart sapma, bağımsız değişkenler ile ölçek alt boyutları arasındaki ilişkilerinin değerlendirilmesinde ise bağımsız gruplarda t- Student testi analizleri kullanarak incelenmiştir. BULGULAR: Bu araştırmada, ölçeğin toplamından alınan puan ortalaması 103,7±22,07’dir. Ölçeğin alt boyutlarından alınan puan ortalamaları ise; yönetim desteği alt boyutu puan ortalaması 3,63±0,66, ortalama meslektaş desteği alt boyutu puan ortalaması 3,73±0,71, birim desteği alt boyutu puan ortalaması 2,77±0,58, çalışma ortamı algısı alt boyutu puan ortalaması 3,52±0,84, ve mevcut işi sürdürme niyeti alt boyutu puan ortalaması 1,04±0,30 olarak bulunmuştur. SONUÇ: Araştırma sonucunda, sağlık çalışanlarının iş yükü desteğini en çok meslektaşlarından aldıkları ve sağlık çalışanların aynı işi sürdürme niyetine ilişkin puanın en düşük puan olduğu bulunmuştur.Article Citation - WoS: 1Citation - Scopus: 1Isocarpine as A New Peperidine Alkaloid from Adenocarpus Complicatus with Anticandidal Activity(Ingenta Connect, 2022) Alhilal, Mohammad; Alhilal, Suzan; Gomha, SobhiBackground: Adenocarpus complicatus L. is one of Adenocarpus genus, which has about 50 species, from Fabaceae (Papilionaceae) family. This plant is found in the Mediterranean basin as a southern west part of Europe and North Afric forestes. Objective: Isolation of Isocarpine From Adenocarpus Complicatus as Anticandidal Agent. Methods: A new piperidine alkaloid Isocarpine was isolated from the aerial parts of Adenocarpus complicatus L., which is gross in Syria. The structure of the new compound was determined by UV, IR, EI-Ms, 1H-NMR, 13C-NMR, DEPT-135, DQF-COSY and HMQC. Results: The anticandidal activity of isocarpine was screened against 38 Candida strains and showed remarkable inhibitory effect compared with fluconazole as an antifungal reference drug. Conclusion: Isocarpine is antifungal agent.
