A Study To Assess the Pharmacological Agent Potential of Gold Nanoparticles and Their Effects on Human Cancer Cells and Hospital Pathogens Using in Vitro Methods

dc.contributor.author Baran, Ayşe
dc.date.accessioned 2025-02-15T19:36:06Z
dc.date.available 2025-02-15T19:36:06Z
dc.date.issued 2025
dc.description.abstract Interest in metal nanoparticles synthesised using green methods is growing steadily. Metal nanoparticles can be synthesised inexpensively and effortlessly using extracts derived from different plants and their diverse components. Gold nanoparticles (Au NPs) were rapidly synthesised from Broccoli (Brassica oleracea L.) agricultural waste using a novel, cost-effective, and eco-friendly method in this work. Analysed data from various techniques including UV-vi, TEM, FESEM, XRD, AFM, FTIR, TGA-DT, EDX, and DLS to assess the properties of the synthesised Au NPs. The characterisation data revealed that the Au NPs had a peak absorbance at 553.10 nm, a surface charge of -19.7 mV, an average hydrodynamic size of 78.75 nm, a monodisperse spherical shape, and were found to be stable. The inhibitory effects of Au NPs with these properties on hospital pathogens and human cancer cells were evaluated by microdilution, disk diffusion and MTT techniquesAs a result of the findings, it was determined that Au NPs have antibacterial, antifungal and anticancer potential as pharmacological agents under in vitro conditions. en_US
dc.identifier.citationcount 0
dc.identifier.doi 10.3389/fphar.2024.1498734
dc.identifier.issn 1663-9812
dc.identifier.scopus 2-s2.0-85215309258
dc.identifier.uri https://doi.org/10.3389/fphar.2024.1498734
dc.identifier.uri https://hdl.handle.net/20.500.12514/6082
dc.language.iso en en_US
dc.publisher Frontiers Media Sa en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Anticancer en_US
dc.subject Antimicrobial en_US
dc.subject Au Nps en_US
dc.subject Broccoli en_US
dc.subject Pharmacological Agent en_US
dc.title A Study To Assess the Pharmacological Agent Potential of Gold Nanoparticles and Their Effects on Human Cancer Cells and Hospital Pathogens Using in Vitro Methods en_US
dc.type Article en_US
dspace.entity.type Publication
gdc.author.institutional Baran, Ayse
gdc.author.scopusid 57224737336
gdc.description.department Artuklu University en_US
gdc.description.departmenttemp [Baran, Ayse] Mardin Artuklu Univ, Grad Educ Inst, Dept Biol, Mardin, Turkiye en_US
gdc.description.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
gdc.description.scopusquality Q1
gdc.description.volume 15 en_US
gdc.description.woscitationindex Science Citation Index Expanded
gdc.description.wosquality Q1
gdc.identifier.pmid 39834814
gdc.identifier.wos WOS:001399309700001
gdc.scopus.citedcount 0
gdc.wos.citedcount 0
relation.isAuthorOfPublication 3bf56afd-8586-4d9c-99d5-d5e66c4c6b15
relation.isAuthorOfPublication.latestForDiscovery 3bf56afd-8586-4d9c-99d5-d5e66c4c6b15

Files