Predictive Value of Nutritional Scores in Non-Valvular Atrial Fibrillation Patients: Insights From the After-2 Study

dc.contributor.author Soner, Serdar
dc.contributor.author Guzel, Tuncay
dc.contributor.author Aktan, Adem
dc.contributor.author Kilic, Raif
dc.contributor.author Arslan, Bayram
dc.contributor.author Demir, Muhammed
dc.contributor.author Ertas, Faruk
dc.date.accessioned 2025-02-15T19:39:43Z
dc.date.accessioned 2025-09-17T14:28:27Z
dc.date.available 2025-02-15T19:39:43Z
dc.date.available 2025-09-17T14:28:27Z
dc.date.issued 2025
dc.description Soner, Serdar/0000-0002-2807-6424 en_US
dc.description.abstract Background and aim: Many scoring systems are used to evaluate malnutrition, but there is no consensus on which scoring system would be more appropriate. We aimed to investigate the effect of malnutrition in patients with non-valvular atrial fibrillation (NVAF) and to compare three scoring systems. Methods and results: A total of 2592 patients with non-valvular AF from 35 different centers in Turkey were included in this prospective study. All participants were divided into two groups: 761 patients who died and 1831 patients who were alive. The malnutrition status of all participants was evaluated with three scoring systems. The primary outcome was all-cause mortality. The mean age of the population was 68.7 +/- 11.1 years, and 55.5 % were female. According to Cox regression analysis, the geriatric nutritional risk index (GNRI) (HR = 0.989, 95 % CI: 0.982-0.997, p = 0.007), controlling nutritional status (CONUT) score (HR = 1.121, 95 % CI: 1.060-1.185, p < 0.001), and prognostic nutritional index (PNI) (HR = 0.980, 95 % CI: 0.962-0.999, p = 0.036) were found to be significant mortality predictors. ROC curve analysis indicated GNRI (AUC = 0.568), CONUT (AUC = 0.572), and PNI (AUC = 0.547) had moderate predictive values. Kaplan-Meier analysis showed that increasing the risk class based on GNRI (p < 0.001) and CONUT (p < 0.001) was associated with decreased survival, while PNI staging had no statistically significant effect (p = 0.266). Conclusions: Malnutrition, determined by three scoring systems, was found to be an independent predictor of all-cause mortality in NVAF patients. Nutritional examination may provide useful information for prognosis and risk stratification in patients with NVAF. en_US
dc.identifier.citationcount 0
dc.identifier.doi 10.1016/j.numecd.2024.103794
dc.identifier.issn 0939-4753
dc.identifier.issn 1590-3729
dc.identifier.scopus 2-s2.0-85214135176
dc.identifier.uri https://doi.org/10.1016/j.numecd.2024.103794
dc.identifier.uri https://hdl.handle.net/20.500.12514/9632
dc.language.iso en en_US
dc.publisher Elsevier Sci Ltd en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Atrial Fibrillation en_US
dc.subject Malnutrition en_US
dc.subject Controlling Nutritional Status en_US
dc.subject Geriatric Nutritional Risk Index en_US
dc.subject Prognostic Nutritional Index en_US
dc.title Predictive Value of Nutritional Scores in Non-Valvular Atrial Fibrillation Patients: Insights From the After-2 Study en_US
dc.type Article en_US
dspace.entity.type Publication

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