Determination of Trace Manganese Contents in Real Samples and Interference Studies by Combining Coated Magnetic Nanoparticle-Assisted Solid-Phase Microextraction With Slotted Quartz Tube-Flame Atomic Absorption Spectrometry

Abstract

This study aimed to propose a sensitive analytical method to determine trace levels of manganese by combining magnetic nanoparticle (MNP)-assisted solid-phase microextraction (SPME) with slotted quartz tube flame atomic absorption spectrometry (SQT-FAAS). MNP was used as an absorbent in the extraction processes, univariately optimizing parameters such as pH, buffer volume, MNP amount, eluent concentration and volume, mixing type and duration, and interaction time to improve extraction efficiency. The limits of detection and quantification values for the developed MNP-SPME-SQT-FAAS method were identified as 108 and 359 μg/dm3, respectively. The coefficient of determination, percentage relative standard deviation, and percentage recovery values were also calculated as 0.9995, 3.84, and 96.73, respectively. As a result, the developed MNP-SPME-SQT-FAAS method improved the detection power of the traditional FAAS method by 16.91-fold. This method is the first to accurately and sensitively determine trace manganese content in nut samples. The developed MNP-SPME-SQT-FAAS method was confirmed that have a high sensitivity to determine the trace amounts of manganese and displayed potential applicability for real samples. © Springer-Verlag GmbH Austria, part of Springer Nature 2025.