Scopus İndeksli Yayınlar Koleksiyonu

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Citation - Scopus: 17
Academic achievement and its relationships with psychological resilience and socio-demographic characteristics
(Routledge, 2018) Sakız, Halis; Aftab, Raiha
This study focused on academic achievement among a sample of 810 students studying in vocational and nonvocational high schools in Turkey. It specifically investigated (a) the current levels of academic achievement and psychological resilience, (b) the relationships between levels of academic achievement and psychological resilience, (c) whether levels of academic achievement and psychological resilience will change based on sociodemographic variables, and (d) whether psychological resilience had a mediating effect on the relationship between sociodemographic variables and academic achievement. Quantitative data were collected through student records and questionnaires and analyzed via descriptive, correlational, and regression analysis and tests of difference (ANOVA). Findings indicated that academic achievement and psychological resilience were significantly related and they changed based on sociodemographic factors, namely income level and school type. In addition, psychological resilience had a significant mediating effect between academic achievement and sociodemographic factors. Findings indicate that the prevailing emphasis on enhancing academic achievement requires consideration of students’ psychological and sociodemographic conditions, while further research needs to investigate ways of carrying out this task. © 2018, © 2018 International School Psychology Association.
Citation - WoS: 18
Citation - Scopus: 21
Activated Carbon-Coated Iron Oxide Magnetic Nanocomposite (ionps@ctac) Loaded With Morin Hydrate for Drug-Delivery Applications
(Frontiers Media Sa, 2024) Dogan, Yusuf; Ozic, Cem; Ertas, Erdal; Baran, Ayse; Rosic, Gvozden; Selakovic, Dragica; Eftekhari, Aziz
Cancer is a major disease that affects millions of people around the world every year. It affects individuals of all ages, races, and backgrounds. Since drugs used to treat cancer cannot distinguish between cancerous and healthy cells, they cause systemic toxicity along with serious side effects. Recently, controlled drug-release systems have been developed to reduce the side effects caused by anticancer drugs used for treatment. Morin is an anticancer drug with a flavonol structure. It has been extensively researched for its antioxidant, anti-inflammatory, antitumoral, and antibacterial properties, especially found in Chinese herbs and fruits, and its multiple positive effects on different diseases. In this study, a nanocomposite with magnetic properties was synthesized by coating biocompatible activated carbon obtained using the fruits of the Celtis tournefortii plant on the surface of iron oxide magnetic nanoparticles. Characterization of the synthesized activated carbon-coated iron oxide magnetic nanocomposite was confirmed by Fourier transform infrared, scanning electron microscopy, energy-dispersive X-ray spectrometry, X-ray diffraction, dynamic light scattering, zeta potential, and vibrating sample magnetometry. The cytotoxic effects of the drug-loaded magnetic nanocomposite were examined in HT-29 (colorectal), T98-G (glioblastoma) cancer cell lines, and human umbilical vein endothelial cell (HUVEC) healthy cell line. The morin loading and release behavior of the activated carbon-coated iron oxide magnetic nanocomposite were studied, and the results showed that up to 60% of the adsorbed morin was released within 4 h. In summary, activated carbon-coated iron oxide magnetic nanocomposite carriers have shown promising results for the delivery of the morin drug.
Citation - Scopus: 1
Activity of nanosized copper-boron alloys against Phytophthora species
(Springer Science and Business Media Deutschland GmbH, 2023) Yiğit, Uğur; Türkkan, Muharrem; İlhan, Hasan; Şimşek, Tuncay; Güler, Ömer; Derviş, Sibel
This study aimed to evaluate the antifungal activity of copper-boron (Cu-B) nanoalloys against a range of Phytophthora species, including P. capsici, P. citrophthora, P. palmivora, P. cinnamomi, P. nicotianae, P. cactorum, P. plurivora, P. inundata, and P. megasperma. The nanoalloys were synthesized via mechanical alloying under an argon atmosphere, resulting in the formation of nanocrystalline Cu-B nanoalloys with irregular morphology and particle sizes ranging from 50 to 240 nm. At a concentration of 250 µg mL−1, the Cu-B nanoalloys demonstrated complete inhibition of mycelial growth, sporangium production, and zoospore germination in all tested Phytophthora species. The EC50 values for mycelial growth ranged from 28.02 to 120.17 µg mL−1, while for sporangium production and zoospore germination, they were below 10 µg mL−1. Furthermore, the nanoalloys exhibited fungicidal activity against specific Phytophthora species, such as P. capsici, P. citrophthora, P. inundata, and P. megasperma, at concentrations of 100, 250, 250, and 250 µg mL−1, respectively. Notably, the Cu-B nanoalloys displayed significant protective and curative effects on tuber rot severity in P. nicotianae-inoculated potatoes, resulting in reductions of 94.13% and 92.61% compared to the control, respectively, at a concentration of 10 µg mL−1 (P < 0.05). These findings highlight the potential of Cu-B nanoalloys as a promising fungicide for the management of plant diseases caused by Phytophthora spp.
Citation - WoS: 19
Citation - Scopus: 19
Acute Toxicity of Deltamethrin on the Fatty Acid Composition of Phospholipid Classes in Liver and Gill Tissues of Nile Tilapia
(Springer Int Publ Ag, 2017) Cengiz, E. I.; Bayar, A. S.; Kizmaz, V.; Bashan, M.; Satar, A.
Deltamethrin is a pyrethroid pesticide contaminating aquatic ecosystems. The purpose of this study was to clarify the acute toxicity of deltamethrin on the fatty acids of phospholipid (PL) classes in liver and gill of Nile tilapia. The fatty acids of PL classes were analyzed by gas chromatography. Deltamethrin brought about differences in the fatty acids of the PL classes in the liver and gill. In the liver of exposed fish, 16:0, 18:2(n-6), 22:6(n-3) in phosphatidylcholine (PC); 16:0, 18:1(n-9), 18:2(n-6), 20:4(n-6), 22:6(n-3) in phosphatidylethanolamine (PE); 16:0, 18:0, 18:1(n-9), 20:4(n-6), 22:6(n-3) in phosphatidylinositol (PI) and in phosphatidylserine (PS) 16:0, 18:1(n-9), 20:4(n-6), 22:6(n-3) were the affected fatty acids. There were significant alterations in Sigma MUFAs (monounsaturated fatty acids), a(n-3)PUFAs (polyunsaturated fatty acids) and Sigma(n-6)PUFAs in PC; Sigma SFAs (saturated fatty acids), Sigma MUFAs, Sigma PUFAs, Sigma(n-3)PUFAs and Sigma(n-6)PUFAs in PE; Sigma SFAs, Sigma MUFAs, Sigma(n-3)PUFAs and Sigma(n-6)PUFAs in PI and Sigma SFAs, Sigma MUFAs,Sigma PUFAs and Sigma(n-3)PUFAs in PS. In the gill, 18:2(n-6), 20:4(n-6), 22:6(n-3) in PC; 16:0, 18:1(n-9), 20:4(n-6), 22:6(n-3) in PE; 16:0, 18:0, 18:1(n-9), 18:2(n-6) in PI and in PS 16:0, 18:0,18:1(n-9), 20:3(n-6), 20:5(n-3), 22:6(n-3) affected. The alterations in Sigma SFAs, Sigma MUFAs, Sigma PUFAs and Sigma(n-6)PUFAs in PC; Sigma SFAs, Sigma MUFAs, Sigma PUFAs, Sigma(n-3)PUFAs and Sigma(n-6)PUFAs in PE; Sigma(n-3)PUFAs and Sigma(n-6)PUFAs in PI; Sigma SFAs, Sigma MUFAs, Sigma PUFAs, Sigma(n-3) PUFAs and Sigma(n-6)PUFAs in PS were significant in gill. The changes in the fatty acids of the PL classes in response to deltamethrin can influence structure and functions of the membrane systems. Changes in fatty acids may be one defense mechanism against the deltamethrin.
Citation - WoS: 1
Citation - Scopus: 1
Adaptation of the Vicarious Resilience Scale To Turkish: a Validity and Reliability Study
(Educational Publishing Foundation - American Psychological Assoc, 2025) Topcu, Feyza; Boz, Canahmet; Seneldir Patolo, Ayse; Kitapcioglu, Sureyyanur; Isiker-Bedir, Deniz; Sanyar, Sema
Objective: The 27-item Vicarious Resilience Scale (VRS) is the first tool developed to measure vicarious resilience in mental health professionals working with trauma survivors. Given that the VRS measures the positive impact on therapists resulting from observing the healing process of trauma victims, it is especially significant to evaluate its validity and reliability in Turkish culture. This study aims to adapt the VRS to Turkish and examine its psychometric properties. Method: VRS was adapted and administered via electronic survey to 337 mental health professionals from around the globe working with survivors of severe traumas, such as earthquake survivors. The validity of the VRS was examined using different techniques: confirmatory factor analysis (CFA) and criterion-related validity. Result: CFA yielded seven factors that were consistent with the original form: changes in life goals and perspective, client-inspired hope, increased recognition of clients' spirituality as a therapeutic resource, increased capacity for resourcefulness, increased self-awareness and self-care practices, increased consciousness of power and privilege relative to clients' social location, and increased capacity for remaining present while listening to trauma narratives. The Cronbach's alpha reliability of the VRS was found to be .95; it displayed positive correlations with posttraumatic growth, psychological resilience, and quality of life, indicating convergent validity. However, it had a negative correlation with depression, anxiety, and stress, indicating discriminant validity. Conclusion: The VRS is a valid and reliable measurement scale by professionals working with trauma survivors to aid the recognition and cultivation of vicarious resilience in Turkish mental health professionals.
Citation - WoS: 19
Citation - Scopus: 20
The Adsorption and Inhibition Efficiency of 2-Amino for Corrosion of Mild Steel in Hydrochloric Acid Solution
(Emerald Group Publishing Ltd, 2023) Okten, Veysi; Yildiz, Resit; Sigircik, Goekmen
PurposeThis study aims to prevent mild steel (MS) against corrosion in 0.5 M HCl solution, 2-amino-4-methoxy-6-methyl-1,3,5-triazine was used. The effectiveness of the compound as a corrosion inhibitor was studied via electrochemical, surface and theoretical calculation techniques. Design/methodology/approachFor concentrations ranging from 0.5 to 10.0 mM, almost similar polarization resistances were obtained from electrochemical impedance spectroscopy (EIS) and linear polarization resistance tests. It also investigated inhibitive activity of 2-amino-4-methoxy-6-methyl-1,3,5-triazine on the steel surface using scanning electron and atomic force microscope instruments. Langmuir adsorption is the best matched isotherm for the adsorption of the inhibitor to the steel surface. FindingsEIS method was used to determine inhibition efficiency, which was determined to be 95.7% for 10.0 mM inhibitor containing acid solution. Density functional theory's predictions for quantum chemistry agreed well with the other experimental results. Originality/valueThe methods used in this study are effective and applicable; the used organic inhibitor is 2-amino-4-methoxy-6-methyl-1,3,5-triazine; and protective effectiveness is important, which is crucial for the task of MS corrosion prevention.
Advanced Fault Classification in Induction Motors for Electric Vehicles Using a Stacking Ensemble Learning Approach
(MDPI, 2025) Benkaihoul, Said; Khadar, Saad; Ozupak, Yildirim; Aslan, Emrah; Almalki, Mishari Metab; Mossa, Mahmoud A.
This study proposes an innovative stacking ensemble learning framework for classifying faults in induction motors utilized in Electric Vehicles (EVs). Employing a comprehensive dataset comprising motor data, such as speed, torque, current, and voltage, the analysis encompasses six distinct conditions: normal operating mode, over-voltage fault, under-voltage fault, overloading fault, phase-to-phase fault, and phase-to-ground fault. The proposed model integrates Gradient Boosting (GB), K-Nearest Neighbors (KNN), Gradient Boosting (XGBoost), Support Vector Machine (SVM), Decision Tree (DT), and Random Forest (RF) algorithms in a synergistic manner. The findings reveal that the RF-GB-DT-XGBoost combination achieves a remarkable accuracy of 98.53%, significantly surpassing other methods reported in the literature. Performance is evaluated through metrics including accuracy, precision, sensitivity, and F1-score, with results analyzed in comparison to practical applications and existing studies. Validated with real-world data, this study demonstrates that the proposed model offers a groundbreaking solution for predictive maintenance systems in the EV industry, exhibiting high generalization capacity despite complex operating conditions. This approach holds transformative potential for both academic research and industrial applications. The dataset used in this study was generated using a MATLAB 2018/Simulink-based Variable Frequency Drive (VFD) model that emulates real-world EV operating conditions rather than relying solely on laboratory data. This ensures that the developed model accurately reflects practical electric vehicle environments.
Citation - WoS: 22
Citation - Scopus: 22
Aflatoxin M1 in Human Breast Milk in Southeastern Turkey
(Springer Heidelberg, 2017) Altun, Serap Kilic; Gurbuz, Semra; Ayag, Emin
This study was performed to determine aflatoxin M-1 (AFM(1)) in human breast milk samples collected in AanlA +/- urfa, located in Southeastern region of Turkey, and to investigate a possible correlation between AFM(1) occurrence (frequency and levels) and sampling seasons. Human breast milk samples collected in December 2014 and in June 2015 from a total of 74 nursing women, both outpatient and inpatient volunteers in hospitals located in AanlA +/- urfa, Turkey, were analyzed using competitive enzyme-linked immunosorbent assay (ELISA) for the presence of AFM(1). AFM(1) was detected in 66 (89.2%) out of 74 samples at an average concentration of 19.0 +/- 13.0 ng/l (min.-max., 9.6-80 ng/l). There was a statistically significant difference between December and June concerning AFM(1) levels (p < 0.05). Further detailed studies will be needed to determine the main sources of aflatoxins in food, to establish protection strategies against maternal and infant exposure to these mycotoxins.
Citation - WoS: 3
Citation - Scopus: 3
Aging and cardiac implantable electronic device complications: is the procedure safe in older patients?
(Springer, 2023) Güzel, Tuncay; Aktan, Adem; Kılıç, Raif; Günlü, Serhat; Arslan, Bayram; Arpa, Abdulkadir; Güzel, Hamdullah; Tatlı, İsmail; Aydın, Saadet; Suzan, Veysel; Demir, Muhammed
Background: In this study, we investigated whether there is a higher incidence of cardiac implantable electronic devices (CIED) procedures related complications in older (≥ 75 years) than in younger (< 75 years) patients. Methods: This retrospective cohort study enrolled patients who had undergone CIED procedures (de novo implantation, system upgrade, generator substitution, pocket revision or lead replacement) at two heart centers in Turkey between January 2011 and May 2023. The primary composite endpoint included clinically significant hematoma (CSH), pericardial effusion or tamponade, pneumothorax, and infection related to the device system. Secondary outcomes included each component of the composite end point. Results: The overall sample included 1923 patients (1419 < 75 years and 504 aged ≥ 75 years). There was no difference between the groups in terms of cumulative events defined as primary outcome (3.5% vs. 4.4%, p = 0.393). Infection related to device system was significantly higher in the ≥ 75 age group (1.8% vs. 3.4%, p = 0.034). There was no significant difference between the groups in terms of clinically significant hematoma and pneumothorax (0.7% vs. 0.4%, p = 0.451, 1.4% vs. 1.0%, p = 0.477, respectively). In multivariate model analysis, no association was found between age ≥ 75 years and infection related to the device system. Conclusion: Infection rates were relatively higher in the patient group aged ≥ 75 years. This patient group should be evaluated more carefully in terms of infection development before and after the procedure.
Citation - WoS: 7
Citation - Scopus: 8
Air Quality Forecasting Using Machine Learning: Comparative Analysis and Ensemble Strategies for Enhanced Prediction
(Springer Int Publ Ag, 2025) Ozupak, Yildirim; Alpsalaz, Feyyaz; Aslan, Emrah
Air pollution poses a critical challenge to environmental sustainability, public health, and urban planning. Accurate air quality prediction is essential for devising effective management strategies and early warning systems. This study utilized a dataset comprising hourly measurements of pollutants such as PM2.5, NOx, CO, and benzene, sourced from five metal oxide sensors and a certified analyzer in a polluted urban area, totaling 9,357 records collected over one year (March 2004-February 2005) from the Kaggle Air Quality Data Set. A comprehensive comparison of ten machine learning regression models XGBoost, LightGBM, Random Forest, Gradient Boosting, CatBoost, Support Vector Regression (SVR) with Bayesian Optimization, Decision Tree, K-Nearest Neighbors (KNN), Elastic Net, and Bayesian Ridge was conducted. Model performance was enhanced through Bayesian optimization and randomized cross-validation, with stacking employed to leverage the strengths of base models. Experimental results showed that hyperparameter optimization and ensemble strategies significantly improved accuracy, with the SVR model optimized via Bayesian optimization achieving the highest performance: an R2 score of 99.94%, MAE of 0.0120, and MSE of 0.0005. These findings underscore the methodology's efficacy in precisely capturing the spatial and temporal dynamics of air pollution.
Ameliorative Effects of Agomelatine Against Doxorubicin-Induced Hepatotoxicity
(BMC, 2025) Savas, Hasan Basri; Sozen, Mehmet Enes; Cuce, Gokhan; Batur, Tuba
Drug-induced hepatotoxicity is a significant impediment to the use of doxorubicin, a commonly employed chemotherapeutic agent with established efficacy in cancer treatment. The present study aimed to determine the potential protective effects of agomelatine against doxorubicin hepatotoxicity in rat toxicity models. Thirty-two rats were divided into four groups: control (with saline administration), Doxo (with 40 mg/kg doxorubicin administration), Doxo + Ago20, and Doxo + Ago40 (with 20 and 40 mg/kg agomelatine administration and 40 mg/kg doxorubicin administration). On the day of 14 rats were sacrificed, samples were collected for comparison of immunohistochemical, hematological, and biochemical analysis. There were statistically significant differences between the study groups in terms of immunohistochemical, hematological, and biochemical parameters. Agomelatine administration reduced the TNF-alpha, and caspase-3, which increased by doxorubicin, and reversed levels of oxidative stress markers altered by doxorubicin (p < 0.05). Doxorubicin induces oxidative stress, apoptosis, and hepatotoxicity. Agomelatine may be favored as a primary antidepressant to mitigate hepatic damage induced by doxorubicin.
Citation - WoS: 1
Citation - Scopus: 1
The Ameliorative Effects of Hesperidin in Rats Developed Hepatotoxicity With Deltamethrin
(Mashhad Univ Med Sciences, 2025) Karabekir, Seda Cetinkaya; Sozen, Mehmet Enes; Ayan, Ilknur Cinar; Savas, Hasan Basri; Cuce, Gokhan; Kalkan, Serpil
Objective(s): Deltamethrin (DLM) is a widely used insecticide in agriculture; however, exposure to it can lead to serious health problems. This study aimed to evaluate the protective effects of hesperidin (HSP), a natural antioxidant, against DLM-induced liver toxicity. Materials and Methods: Thirty-two male Wistar Albino rats (250-300 g, 4 months old) were divided into four groups. The control group received 1 ml of corn oil via oral gavage for 30 days. The DLM group received 1.28 mg/kg DLM in corn oil for 30 days. The DLM+HSP 100 mg/kg and DLM+HSP 300 mg/kg groups received 1.28 mg/kg DLM followed by 100 mg/kg or 300 mg/kg HSP in distilled water, respectively, 30 min after DLM administration for 30 days. Liver tissues were examined histopathologically. Masson's trichrome staining and PCR assessed fibrosis. Caspase 3 and 9 expressions in liver tissues were determined by immunohistochemistry and PCR. Biochemical analyses were conducted on serum samples. Results: HSP supplementation led to a dose-dependent decrease in aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels. DLM exposure decreased antioxidant capacity, while HSP supplementation increased it dose-dependently. Histopathological evaluations showed increased liver damage in the DLM group, while HSP administration reduced liver toxicity. Masson's trichrome staining and analysis of collagen I (COL1A1) and collagen III (COL3A1) gene expression revealed increased fibrosis in the DLM group, which was attenuated with HSP treatment. Conclusion: The potential prevention of DLM-induced liver toxicity and apoptosis by HSP may be an alternative protective strategy.
An Unexpected Cause of Tension Pneumothorax: A Case Report
(John Wiley and Sons Inc, 2025) Talay, M.N.; Sızlanan, A.; Gungor, E.; Kalkan, F.; Orhan, Ö.; Nayir-Buyuksahin, H.
Citation - WoS: 201
Citation - Scopus: 338
Analysis and Mitigation of Power Quality Issues in Distributed Generation Systems Using Custom Power Devices
(IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC, 2018) Hossain, Eklas; Tur, Mehmet Rida; Padmanaban, Sanjeevikumar; Ay, Selim; Khan, Imtiaj
This paper discusses the power quality issues for distributed generation systems based on renewable energy sources, such as solar and wind energy. A thorough discussion about the power quality issues is conducted here. This paper starts with the power quality issues, followed by discussions of basic standards. A comprehensive study of power quality in power systems, including the systems with dc and renewable sources is done in this paper. Power quality monitoring techniques and possible solutions of the power quality issues for the power systems are elaborately studied. Then, we analyze the methods of mitigation of these problems using custom power devices, such as D-STATCOM, UPQC, UPS, TVSS, DVR, etc., for micro grid systems. For renewable energy systems, STATCOM can be a potential choice due to its several advantages, whereas spinning reserve can enhance the power quality in traditional systems. At Last, we study the power quality in dc systems. Simpler arrangement and higher reliability are two main advantages of the dc systems though it faces other power quality issues, such as instability and poor detection of faults.
Citation - WoS: 7
Citation - Scopus: 7
Analysis of bioactive compounds using LC-ESI-MS/MS, cytotoxic, antimicrobial effects, and enzyme activities from Cyclotrichium origanifolium
(Wiley Online Library, 2022) Aktepe, Necmettin; Baran, Ayşe; Atalar, Mehmet Nuri; Baran, Mehmet Fırat; Keskin, Cumali; Taşkin, Abdullah; Yavuz, Ömer; Demirtaş, İbrahim; Oğuz, Ercan; Jahan, Israt
Cyclotrichium origanifolium is a medicinal plant belonging to the Lamiaceae family. In this study, phenolic content analysis, antimicrobial effects, and cytotoxic effects of extracts of C. origanifolium were investigated. In the extracts, phenolic compound analysis by the liquid chromatography–electrospray ionization– tandem mass spectrometry method, antimicrobial effect by the minimum inhibition concentration method, and cytotoxic effect on human dermal fibroblasts (HDF), glioblastoma cell (U87), ovarian adenocarcinoma cell (Skov-3), and human colorectal adenocarcinoma cell (CaCo-2) cancer cell lines were investigated. Cytotoxicity analyses were performed by the MTT method. In addition, the GST and AChE enzyme activities of the extracts were also measured. Around 18 compounds were detected in both the methanol and ethanol extract. It was found that the best antimicrobial effect on Gram-negative Pseudomonas aeruginosa was on methanol extract, while the ethanol extract was on Candida albicans fungus (respectively, 2.50mg/ml, 5.0 μg/ml). A 500μg/ml of methanol extract has been shown to have cytotoxic activity high effect on HDF cells. GST and AChE activity were found to decrease in a concentration-dependent manner.
Citation - WoS: 2
Citation - Scopus: 2
Analysis of Lipid Classes and the Fatty Acid Composition of Fresh and the Salted Fish, Alburnus Tarichi
(Taylor & Francis Ltd, 2022) Kizmaz, Veysi
This study was carried out to determine the distribution of total, phospholipid and triacylglycerol fatty acid composition in salted and fresh fish of pearl mullet. Fatty acid analyses were performed in muscle tissues of the fish samples. Eicosapentaenoic acid (EPA), Docosahexaenoic acid (DHA), Omega-3 (n-3), Omega-6 (n-6) which are important for health, were determined in the analyses. The distribution of total and TAG fatty acids in males and females was similar. It was determined that the changes were in the Phospholipid. N-3/n-6 ratio showed a similar distribution in both female and male individuals. In particular, the results obtained may benefit the fisheries industry, nutritionists and researchers, as the nutritional value of the fish is high.
Anatomical Examination of Intraparotid Lymph Nodes in Various Tumors of Parotid Gland Using Magnetic Resonance Imaging
(Elsevier Science Inc, 2025) Selcuk, Mehmet; Dogan, Nadire Unver; Onal, Merih; Batur, Abdussamet; Karabulut, Ahmet Kagan; Fazliogullari, Zeliha
Objective. This retrospective study aimed to anatomically compare the morphometric measurements of intraparotid lymph nodes across different parotid gland tumors and a control group. Study Design. The study used retrospective images of patients admitted to the Department of Otorhinolaryngology over the past 10 years from the Radiology Department archive at Sel,cuk University Medical Faculty Hospital. A total of 160 individuals were included in our study.Long-axis diameter (LAD) and short-axis diameter (SAD) were measured in axial section on magnetic resonance images. Results. In all patients, the mean SAD and LAD were significantly higher on the lesion (+) side compared to the lesion (-) side (P < .05). The mean SAD and LAD were significantly larger on the lesion (+) side compared to the control group (P < .05). Conclusions. In our findings, if the SAD exceeded 3.51 mm and the LAD exceeded 4.85 mm in the control group, it can be considered suspicious in terms of lymph node abnormality, potential pathologic evaluation, and indications for further examination. (Oral Surg Oral Med Oral Pathol Oral Radiol 2025;140:759-768)
Citation - WoS: 24
Citation - Scopus: 31
Antibiotic Removal from the Aquatic Environment with Activated Carbon Produced from Pumpkin Seeds
(Molecules, 2022) Alacabey, İhsan
Antibiotics are among the most critical environmental pollutant drug groups. Adsorption is one of the methods used to eliminate these pollutants. In this study, activated carbon was produced from pumpkin seed shells and subsequently modified with KOH. The adsorbent obtained through this procedure was used to remove ciprofloxacin from aqueous systems. Fourier Transform-Infrared Spectroscopy (FT-IR), Scanning Electron Microscopy (SEM), elemental, X-ray Photoelectron Spectroscopy (XPS), Brunauer–Emmett–Teller (BET) and Zeta analyses were used to characterize the adsorbent. The surface area, in particular, was found to be a very remarkable value of 2730 m2/g. The conditions of the adsorption experiments were optimized based on interaction time, adsorbent amount, pH and temperature. Over 99% success was achieved in removal operations carried out under the most optimal conditions, with an absorption capacity of 884.9 mg·g−1. In addition, the Langmuir isotherm was determined to be the most suitable model for the adsorption interaction
Citation - WoS: 1
Citation - Scopus: 1
Antidepressant-Like Effects of Ashwagandha (Withania Somnifera) on Chronic Unpredictable Mild Stress-Induced Depression in Adolescent Rats
(Springer, 2025) Gokdemir, Gul Sahika; Seker, Ugur; Baksi, Nazan; Baylan, Mukadder; Demirtas, Berjan; Gokdemir, Mehmet Tahir
RationaleAdolescent depression is often linked to biological changes associated with stress. However, new approaches and treatment strategies for early intervention and prevention of depression in children and adolescents are still limited. Ashwagandha is an Ayurvedic herb widely used in the management of anxiety and stress. However, there is no information in the current literature on its potential effect on adolescent depression.ObjectivesThis study aimed to investigate the effects of depression on proapoptotic proteins and neuroinflammation and the antidepressant effect of Ashwagandha on depression-like symptoms in adolescent rats exposed to the Chronic Unpredictable Mild Stress (CUMS) model.MethodsIn the study, CUMS model was used to induce depression in adolescent rats. Rats were treated with Ashwagandha or Sertraline. To evaluate the antidepressant effects, behavioral tests as well as biochemical and histological analyses were performed. Forced Swim Test (FST), Sucrose Test and Elevated Plus Maze Test were performed as behavioral tests. Brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) were measured by the ELISA method in the fronto-parietal cortex. Proapoptotic proteins (Bax and Caspase-3) and inflammatory markers (TNF-alpha and IL-1 beta), as well as glial fibrillary acidic protein (GFAP), were evaluated immunohistochemically in the fronto-parietal cortex.ResultsProapoptotic proteins (Bax and Caspase-3) and inflammatory markers (TNF-alpha and IL-1 beta) were increased in the CUMS group. BDNF and GFAP levels were decreased. Ashwagandha treatment was more effective than Sertraline in reducing the levels of these proteins and markers. Additionally, Ashwagandha prevented weight loss.ConclusionsAshwagandha showed antidepressant-like effects in adolescent rats, reducing apoptosis, inflammation, and neuroinflammation, suggesting potential for treating adolescent depression.
Citation - WoS: 22
Citation - Scopus: 22
Antioxidant Properties of Cultured Mycelia from Four Pleurotus Species Produced in Submerged Medium
(TAYLOR & FRANCIS INC, 2013) Dundar, Abdurrahman; Okumus, Veysi; Ozdemir, Sadin; Yildiz, Abdunnasir
The ethanolic extracts of dried cultured mycelia of Pleurotus ostreatus, Pleurotus eryngii, Pleurotus florida, and Pleurotus sajor-caju were analyzed for antioxidant activity in different systems. Tests used are as follows: reducing power, free radical scavenging, superoxide anion radical scavenging, total antioxidant activity, metal chelating activitiy, etc.; total phenolic content was determined. The percentage inhibition of P. ostreatus, P. eryngii, P. florida, and P. sajor-caju at 20 mg/mL concentration on peroxidation in a -carotenelinoleic acid system was 57.19, 60.68, 62.12, and 58.81%, respectively. The reducing power of P. eryngii was higher than the other samples, and its value was 0.86 at 10 mg/mL concentration. P. ostreatus and P. sajor-caju proved to be better at scavenging superoxide anion radicals than the P. eryngii and P. florida. In the scavenging effect of DPPH radical test, P. ostreatus showed the highest activity potential and P. sajor-caju showed the strongest metal chelating capacity.

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