The Effect of Aortic Angulation on Clinical Outcomes of Patients Undergoing Transcatheter Aortic Valve Replacement

dc.contributor.author Aktan, Adem
dc.contributor.author Demir, Muhammed
dc.contributor.author Aslan, Burhan
dc.contributor.author Guzel, Tuncay
dc.contributor.author Karahan, Mehmet Zulkuf
dc.contributor.author Kilic, Raif
dc.contributor.author Ertas, Faruk
dc.date.accessioned 2025-02-15T19:39:14Z
dc.date.accessioned 2025-09-17T14:28:26Z
dc.date.available 2025-02-15T19:39:14Z
dc.date.available 2025-09-17T14:28:26Z
dc.date.issued 2024
dc.description.abstract Introduction: The aim of this study was to assess the impact of aortic angulation (AA) on periprocedural and in -hospital complications as well as mortality of patients undergoing Evolut (TM) R valve implantation. Methods: A retrospective study was conducted on 264 patients who underwent transfemoral-approach transcatheter aortic valve replacement with self-expandable valve at our hospital between August 2015 and August 2022. These patients underwent multislice computer tomography scans to evaluate AA. Transcatheter aortic valve replacement endpoints, device success, and clinical events were assessed according to the definitions provided by the Valve Academic Research Consortium -3. Cumulative events included paravalvular leak, permanent pacemaker implantation, new-onset stroke, and in -hospital mortality. Patients were divided into two groups, AA <= 48(degrees) and AA > 48(degrees), based on the mean AA measurement (48.3 +/- 8.8) on multislice computer tomography. Results: Multivariable logistic regression analysis was performed to identify predictors of cumulative events, utilizing variables with a P-value < 0.2 obtained from univariable logistic regression analysis, including AA, age, hypertension, chronic renal failure, and heart failure. AA (odds ratio [OR]: 1.73, 95% confidence interval [CI]: 0.89-3.38, P=0.104), age (OR: 1.04, 95% CI: 0.99-1.10, P=0.099), hypertension (OR: 1.66, 95% CI: 0.82-3.33, P=0.155), chronic renal failure (OR: 1.82, 95% CI: 0.92-3.61, P=0.084), and heart failure (OR: 0.57, 95% CI: 0.27-1.21, P=0.145) were not found to be significantly associated with cumulative events in the multivariable logistic regression analysis. Conclusion: This study demonstrated that increased AA does not have a significant impact on intraprocedural and periprocedural complications of patients with new generation self-expandable valves implanted. en_US
dc.identifier.citationcount 0
dc.identifier.doi 10.21470/1678-9741-2022-0436
dc.identifier.issn 0102-7638
dc.identifier.issn 1678-9741
dc.identifier.scopus 2-s2.0-85186311284
dc.identifier.uri https://doi.org/10.21470/1678-9741-2022-0436
dc.identifier.uri https://hdl.handle.net/20.500.12514/9616
dc.language.iso en en_US
dc.publisher Soc Brasil Cirurgia Cardiovasc en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Aortic Angulation en_US
dc.subject Aortic Stenosis en_US
dc.subject Transcatheter Aortic Valve Replacement en_US
dc.subject Logistic Models en_US
dc.title The Effect of Aortic Angulation on Clinical Outcomes of Patients Undergoing Transcatheter Aortic Valve Replacement en_US
dc.type Article en_US
dspace.entity.type Publication

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