WoS İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12514/3595

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3D biomechanical analysis of targeted and non-targeted drag flick shooting technique in field hockey
(Drustvo Pedagoga Tjelesne & Zdravstvene Kulture, 2018) Eskiyecek, Canan Gülbin; Bingül, Bergun Meriç; Bulgan, Ciğdem; Aydın, Mensure
The aim of this study was to compare targeted and non-targeted drag flick field hockey shooting techniques in the penalty corner area, using a three-dimensional kinematic analysis. Eleven male field hockey players playing in the super league (mean age: 19,82 +/- 1,40 years) participated voluntarily. Seven high-speed cameras (Oqus 7+) with 120Hz refresh rates were used. Field calibration was completed via the wand method. The data were evaluated in two phases: start and finish. Players undertook three drag flick shots to the box using targeted and non-targeted techniques. The angular kinematics and stroke force applied to the stick were analyzed using the Qualisys Track Manager Program V2.12, and ball velocity statistics were gathered with the SPSS 18.0 program. To compare between the targeted and non-targeted shots of the drag flick shooting techniques, t-test was applied. At the drag flick of the players, significant differences were noticed at the angular speed of the right shoulder and the left knee, and the angular acceleration of the right hip in the starting phase, and also at the right hip angular acceleration at the finish phase. When the ball speed data considered, a significant decrease was observed between the targeted and non-targeted drag flick shots. Significant correlation was found out between some variables, at the angular kinematics and both force applied on the stick and the ball speed values (p <= 0.05). In conclusion, to make an accurate target shot the players maximize their targeted shooting rates, particularly by decreasing the speed of their lower extremities.
Abluted capitalism: Ali Shariati's critique of capitalism in his reading of Islamic Economy
(Sage, 2015) Şengül, Serdar
Islamic sociologist Ali Shariati is a leading figure of the reconstruction of religious thought in the Islamic world known especially for his anti-capitalist stance and leftist reading of Islamic history. In the philosophy of history that he developed, he classified religions as religions of tawheed (unicity of God) and religions of shirk (multiple gods). According to this new reading of history, the main struggle is not between religion and secularism but between religions of tawheed and of sheerk. The issue of the gaining and the distribution of the property is central to his classification. Shariati argued that followers of tawheed and of sheerk can be found in all religions including Islam. To support his argument Shariati explored how capitalistic understanding of Islam has been developed and legalised while anti-capitalist messages and orders of Islam were marginalised and illegalised just after the death of the Prophet Mohammed. He analysed the rivalry between his close companions over the content of a proper Islamic economic order and how this rivalry gave way to two contradicting understanding of Islam, marks of which can be seen today in the contemporary Muslim world. He coined the term abluted capitalism' to define the economic policies of Muslim sovereigns to make Islam compatible with capitalist economic principles.
Activity of nanosized copper-boron alloys against Phytophthora species
(Springer Science and Business Media Deutschland GmbH, 2023) Yiğit, Uğur; Türkkan, Muharrem; İlhan, Hasan; Şimşek, Tuncay; Güler, Ömer; Derviş, Sibel
This study aimed to evaluate the antifungal activity of copper-boron (Cu-B) nanoalloys against a range of Phytophthora species, including P. capsici, P. citrophthora, P. palmivora, P. cinnamomi, P. nicotianae, P. cactorum, P. plurivora, P. inundata, and P. megasperma. The nanoalloys were synthesized via mechanical alloying under an argon atmosphere, resulting in the formation of nanocrystalline Cu-B nanoalloys with irregular morphology and particle sizes ranging from 50 to 240 nm. At a concentration of 250 µg mL−1, the Cu-B nanoalloys demonstrated complete inhibition of mycelial growth, sporangium production, and zoospore germination in all tested Phytophthora species. The EC50 values for mycelial growth ranged from 28.02 to 120.17 µg mL−1, while for sporangium production and zoospore germination, they were below 10 µg mL−1. Furthermore, the nanoalloys exhibited fungicidal activity against specific Phytophthora species, such as P. capsici, P. citrophthora, P. inundata, and P. megasperma, at concentrations of 100, 250, 250, and 250 µg mL−1, respectively. Notably, the Cu-B nanoalloys displayed significant protective and curative effects on tuber rot severity in P. nicotianae-inoculated potatoes, resulting in reductions of 94.13% and 92.61% compared to the control, respectively, at a concentration of 10 µg mL−1 (P < 0.05). These findings highlight the potential of Cu-B nanoalloys as a promising fungicide for the management of plant diseases caused by Phytophthora spp.
Actors: Kurdish National, Religious and Economic Blocs
(I B Tauris & Co Ltd, 2017) Cicek, Cuma
[No Abstract Available]
Acute Cyanide Intoxication Due To Apricot Seed Ingestion
(Soc Argentina Pediatria, 2024) Talay, Mehmet N.; Gungor, Emre; Orhan, Ozhan
Introduction : Cyanide poisoning, whether it be accidental or intentional, remains a significant danger to adults and children, especially in societies where agriculture is a primary source of income. We examined the clinical follow-up, complications, and results of cyanide poisoning cases that occurred after eating the pits and seeds of plants containing cyanide glycosides, such as apricot kernels and almonds. Methods : Between 01/01/2017 and 01/08/2022, 14 children aged 1-18 years who were followed up with a prediagnosis of cyanide poisoning in our Paediatric Intensive Care Unit (PICU) were retrospectively analysed. Results : Eight of the patients followed with a preliminary diagnosis of cyanide poisoning were female and six were male. The most common admission month was July (42.8%) coinciding with the agricultural season. The most common symptoms at presentation were weakness and fatigue (n = 7). In the PICU, 4 patients presented lip cyanosis; 3, altered level of consciousness. Vomiting, seizure, headache, dizziness and palpitatons were less frequent. Four patients were treated with hydroxocobalamin (Cyanokit (R) ) as an antidote due to acidosis in their blood gases. All patients treated for cyanide poisoning were discharged. Conclusions : Cyanide poisoning should be considered in paediatric patients with suspicious findings, sudden loss of consciousness, increased anion gap acidosis and lactic acidosis. The history of eating the seeds of plants such as apricot and almonds should be investigated .
Acute Cyanide Poisoning Due To Ingestion of Apricot Seeds
(Soc Argentina Pediatria, 2024) Talay, Mehmet N.; Gungor, Emre; Orhan, Ozhan
[No Abstract Available]
Adaptation of the Vicarious Resilience Scale To Turkish: a Validity and Reliability Study
(American Psychological Association, 2025) Topçu, F.; Boz, C.; Şeneldir-Patolo, A.; Kitapçıoğlu, S.; Işıker-Bedir, D.; Sanyar, S.
Objective: The 27-item Vicarious Resilience Scale (VRS) is the first tool developed to measure vicarious resilience in mental health professionals working with trauma survivors. Given that the VRS measures the positive impact on therapists resulting from observing the healing process of trauma victims, it is especially significant to evaluate its validity and reliability in Turkish culture. This study aims to adapt the VRS to Turkish and examine its psychometric properties. Method: VRS was adapted and administered via electronic survey to 337 mental health professionals from around the globe working with survivors of severe traumas, such as earthquake survivors. The validity of the VRS was examined using different techniques: confirmatory factor analysis (CFA) and criterion-related validity. Results: CFA yielded seven factors that were consistent with the original form: changes in life goals and perspective, client-inspired hope, increased recognition of clients’ spirituality as a therapeutic resource, increased capacity for resourcefulness, increased self-awareness and self-care practices, increased consciousness of power and privilege relative to clients’ social location, and increased capacity for remaining present while listening to trauma narratives. The Cronbach’s α reliability of the VRS was found to be.95; it displayed positive correlations with posttraumatic growth, psychological resilience, and quality of life, indicating convergent validity. However, it had a negative correlation with depression, anxiety, and stress, indicating discriminant validity. Conclusion: The VRS is a valid and reliable measurement scale by professionals working with trauma survivors to aid the recognition and cultivation of vicarious resilience in Turkish mental health professionals. © 2025 American Psychological Association
Adsorption and inhibition effect of 2,4-diamino-6-hydroxypyrimidine for mild steel corrosion in HCl medium: experimental and theoretical investigation
(SPRINGER HEIDELBERG, 2019) Yildiz, Resit; Yıldız, Reşit
2,4-Diamino-6-hydroxypyrimidine (2D6H) was examined as corrosion inhibitor of mild steel (MS) in 0.1M HCl using potentiodynamic measurements, linear polarization resistance (LPR), scanning electron microscopy, electrochemical experiments, and quantum chemical calculations. All measurements show that the corrosion inhibition effectiveness is forthright compared to the concentration of 2D6H ranging from 0.5 to 10.0mM. Adsorption of 2D6H on the MS surface in the presence of HCl is determined to obey Langmuir adsorption isotherm. The electronic features elucidated by quantum chemical calculations were associated with the experimental inhibition productivities. The mechanism of inhibition was revealed by E-pzc measurements.
The Adsorption and Inhibition Efficiency of 2-Amino for Corrosion of Mild Steel in Hydrochloric Acid Solution
(Emerald Group Publishing Ltd, 2023) Okten, Veysi; Yildiz, Resit; Sigircik, Goekmen; Yıldız, Reşit
PurposeThis study aims to prevent mild steel (MS) against corrosion in 0.5 M HCl solution, 2-amino-4-methoxy-6-methyl-1,3,5-triazine was used. The effectiveness of the compound as a corrosion inhibitor was studied via electrochemical, surface and theoretical calculation techniques. Design/methodology/approachFor concentrations ranging from 0.5 to 10.0 mM, almost similar polarization resistances were obtained from electrochemical impedance spectroscopy (EIS) and linear polarization resistance tests. It also investigated inhibitive activity of 2-amino-4-methoxy-6-methyl-1,3,5-triazine on the steel surface using scanning electron and atomic force microscope instruments. Langmuir adsorption is the best matched isotherm for the adsorption of the inhibitor to the steel surface. FindingsEIS method was used to determine inhibition efficiency, which was determined to be 95.7% for 10.0 mM inhibitor containing acid solution. Density functional theory's predictions for quantum chemistry agreed well with the other experimental results. Originality/valueThe methods used in this study are effective and applicable; the used organic inhibitor is 2-amino-4-methoxy-6-methyl-1,3,5-triazine; and protective effectiveness is important, which is crucial for the task of MS corrosion prevention.
Adsorption of nickel(II) ions from aqueous solutions using Malatya clay: Equilibrium, kinetic, and thermodynamic studies
(Environmental Progress & Sustainable Energy, 2023) Baran, Ayşe; Dal, Mehmet Can; Onursal, Nilgün; Altunkaynak, Yalçın
This paper evaluates Malatya clay (MC) for the removal of Ni(II) ions from aqueous solutions. For adsorption efficiency, the impacts of several factors, such as pH, starting metal ion concentration, and contact duration, were examined. The optimal initial Ni(II) ion concentration was determined to be 5 mg/L, the adsorption contact duration was 360 min, and the solution's pH was 6.27. Using scanning electron microscopy, energy dispersive spectroscopy, and Fourier transform infrared spectroscopy, the surface characteristics of Malatya clay were examined. The isotherm data fit the Langmuir isotherm model, indicating chemical adsorption and likely irreversibility of the process, according to the results. At 298, 308, and 318 K, the adsorption capacities of Ni(II) were determined to be 10.267, 11.834, and 12.285 mg/g, respectively. Adsorption kinetic data revealed that the adsorption of Ni(II) metal ions followed the pseudosecond-order kinetic model. According to thermodynamic studies, Ni(II) ion adsorption on the MC is spontaneous and endothermic. MC has proven to be an effective and alternative material for the removal of Ni(II) ions from aqueous media due to its excellent removal ability, availability, and low cost, as well as its features such as being able to be used without any chemical treatment and being environmentally friendly.
Adsorption Performance of bacillus Licheniformis Sp. Bacteria Isolated From the Soil of the Tigris River on Mercury in Aqueous Solutions
(Taylor & Francis Ltd, 2022) Baran, M. Firat; Yildirim, Ayfer; Acay, Hilal; Keskin, Cumali; Aygun, Husamettin
Mercury is known to be one of the most toxic heavy metals in the environment and is released into the water systems in significant quantities through natural events and industrial process activities. Many chemical materials are used as adsorbents in the removal of toxic metals from the environment and wastewaters. However, using microorganisms as bio-sorbents instead of chemical materials has become common recently due to their low cost, easy availability and presence in nature. In this study, Bacillus licheniformis in the soil isolated from the Tigris River was used as bio-sorbent. The mercury (Hg(II)) absorption behaviour of Bacillus licheniformis bacteria (BLB) was investigated using inductively coupled plasma mass spectrometry. The effects of equilibrium of adsorption time, temperature, adsorbent dosage and pH on the adsorption of Hg (II) onto BLB were determined. The maximum adsorption capacity of Hg (II) onto BLB was determined as 82.12 mg/g (T = 25 degrees C, pH 5, Co = 50 mg/L, m = 25 mg). The BLB was characterised using Fourier transform infrared spectroscopy analysis, thermal gravimetric analysis/differential thermal analysis, scanning electron microscopy analysis and energy-dispersive X-ray spectroscopy analysis. In addition, pseudo-first-order and pseudo-second-order kinetic models were applied. The equilibrium data for the adsorption of Hg(II) onto BLB were examined by the Langmuir and Freundlich isotherm models. The activation energy was calculated using the pseudo-second-order rate constant. These results suggested the BLB can be used as an efficient adsorbent for the removal of Hg(II) metal ions from wastewater. When the results of bio-sorption studies were examined, it was found that the bio-sorbent could be reused easily. The present study suggests that microorganism bio-sorbents are useful for the efficient removal of mercury from aqueous solutions.
AFLATOXIN M-1 IN TRADITIONAL HOMEMADE YOGHURTS MARKETED IN SOUTHEASTERN TURKEY
(PARLAR SCIENTIFIC PUBLICATIONS (P S P), 2019) Gürbüz, Semra; Kılıç Altun, Serap
This study was performed to determine the presence and levels of aflatoxin M-1 (AFM(1)) in yoghurt produced by traditional methods in small scale enterprises in Mardin and Sanliurfa provinces located in Southeastern Turkey and to evaluate the yoghurt in terms of food safety. A total of 90 yoghurt samples, 42 from Mardin and 48 from $anhurfa were collected from small-scale retailers and tested for AFM(1) by enzyme-linked immunosorbent assay (ELISA). AFM(1) was detected in 34 (37.8 %) of 90 yoghurt samples at the levels ranging from 10 to 515 ng/kg. Five (11.9 %) samples (ranging from 10 to 515 ng/kg) from Mardin and 29 (60.4 %) samples (ranging from 10 to 101 ng/kg) from Sanliurfa were found to be contaminated with AFM(1). There was a statistically significant difference between the samples collected Mardin and Sanliurfa concerning the presence frequency of AFM(1) (p=0.000). The AFM(1) levels of 16 (17.8 %) positive yoghurt samples were higher than the legal limits. The results of this study have revealed that the traditionally produced homemade yoghurt is contaminated with AFM(1) and poses health risk for consumers.
Aflatoxin M1 in Human Breast Milk in Southeastern Turkey
(Springer Verlag, 2017) Kılıç Altun, S.; Gürbüz, S.; Ayağ, E.
This study was performed to determine aflatoxin M1 (AFM1) in human breast milk samples collected in Şanlıurfa, located in Southeastern region of Turkey, and to investigate a possible correlation between AFM1 occurrence (frequency and levels) and sampling seasons. Human breast milk samples collected in December 2014 and in June 2015 from a total of 74 nursing women, both outpatient and inpatient volunteers in hospitals located in Şanlıurfa, Turkey, were analyzed using competitive enzyme-linked immunosorbent assay (ELISA) for the presence of AFM1. AFM1 was detected in 66 (89.2%) out of 74 samples at an average concentration of 19.0 ± 13.0 ng/l (min.-max., 9.6–80 ng/l). There was a statistically significant difference between December and June concerning AFM1 levels (p < 0.05). Further detailed studies will be needed to determine the main sources of aflatoxins in food, to establish protection strategies against maternal and infant exposure to these mycotoxins. © 2016, Society for Mycotoxin Research and Springer-Verlag Berlin Heidelberg.
Aging and cardiac implantable electronic device complications: is the procedure safe in older patients?
(Springer, 2023) Güzel, Tuncay; Aktan, Adem; Kılıç, Raif; Günlü, Serhat; Arslan, Bayram; Arpa, Abdulkadir; Güzel, Hamdullah; Tatlı, İsmail; Aydın, Saadet; Suzan, Veysel; Demir, Muhammed
Background: In this study, we investigated whether there is a higher incidence of cardiac implantable electronic devices (CIED) procedures related complications in older (≥ 75 years) than in younger (< 75 years) patients. Methods: This retrospective cohort study enrolled patients who had undergone CIED procedures (de novo implantation, system upgrade, generator substitution, pocket revision or lead replacement) at two heart centers in Turkey between January 2011 and May 2023. The primary composite endpoint included clinically significant hematoma (CSH), pericardial effusion or tamponade, pneumothorax, and infection related to the device system. Secondary outcomes included each component of the composite end point. Results: The overall sample included 1923 patients (1419 < 75 years and 504 aged ≥ 75 years). There was no difference between the groups in terms of cumulative events defined as primary outcome (3.5% vs. 4.4%, p = 0.393). Infection related to device system was significantly higher in the ≥ 75 age group (1.8% vs. 3.4%, p = 0.034). There was no significant difference between the groups in terms of clinically significant hematoma and pneumothorax (0.7% vs. 0.4%, p = 0.451, 1.4% vs. 1.0%, p = 0.477, respectively). In multivariate model analysis, no association was found between age ≥ 75 years and infection related to the device system. Conclusion: Infection rates were relatively higher in the patient group aged ≥ 75 years. This patient group should be evaluated more carefully in terms of infection development before and after the procedure.
Ahmed Anzavur: Soldier, Governor, and Rebel. a Reevaluation of a Late Ottoman Military Man
(Oriental inst Czech Acad Sci, 2023) Yelbasi, Caner
Following the Russian conquest of the North Caucasus, many Muslims from the region were exiled to the Ottoman Empire from the 1860s onwards. They were settled in different parts of the empire from the Balkans to Anatolia to the Syria and Iraq vilayets. By following this policy, the Ottoman state ensured that many Circassians would become part of the Ottoman army, ruling elites, harems and agricultural workforce. Anzavur Ahmed's family was one of them. Although he did not graduate from military school, he participated in the army during the war in Libya (1911), the Balkan Wars (1912-1913), and the First World War (1914-1918). He was also appointed as the governor of Izmit (1920). Anzavur Ahmet is portrayed as a rebel by Turkish official historiography, but in reality, he was much more than that. He was an Ottoman Governor, and supported by Ottoman administrators such as Damad Ferid and Ali Kemal, who were against the Kuvayi Milliye because they believed that the empire would eventually emerge from the chaotic atmosphere of the post-First World War period and make an agreement with the British. This article argues that although Ahmed Anzavur has been labeled a rebel and a traitor according to the official historiography, it is difficult to use these labels given the circumstances of his time.
Ali Al-tusi's Contributions To the Seventeenth Discussion of Al-ghazali's Tahafut
(Beytulhikme Felsefe Cevresi, 2016) Kilic, Muhammet Fatih
In this paper, I analyze the 17th chapter of a 15th century Tahafut work by Ali al-Tusi which is devoted to the problem of causality. This analysis argues that Ali al-Tusi agrees with alGhazali's 17th discussion of causality and presents a number of conceptual and argumentative structures. Like al-Ghazali, Ali al-Tusi argues that the ontological relationship between cause and effect is not necessary and that this non-necessity does not weaken the certainty of our knowledge of the causal order. Ali al-Tusi differs from al-Ghazali by utilizing the concept of nafs al-amr in order to deny causal necessity, applying the distinction between true and ordinary causality for the two realms of causality (i.e. physical and metaphysical), and focusing on the contradictions between the physical and metaphysical explanations of the philosophers' theories of motion. Consequently, Ali al-Tusi's Tahafut cannot be considered as a commentary in the narrow sense, because he goes beyond the original context of al-Ghazali by taking into account post-classical thought on causality.
Alternaria alternata causing inner black rot of lemon (Citrus limon) fruits in Turkey: Genetic diversity and characterisation
(ScienceDirect, 2023) Güney, İnci Güler; Derviş, Sibel; Fatih Tekin, Tacettin Utku Günen, Göksel Özer
The market sales of symptomless lemons in 2020 revealed a persistent and severe internal black rot with browning of the membrane wall and juice sac. To investigate the causal agent, externally symptom-free lemons from Mediterranean locations were sampled from supermarkets, local markets, and bazaars in three southeastern Turkish provinces. Internal black rot symptoms were observed in 13.69% of the 1300 externally symptomless fruits, and Alternaria was isolated from 96.63% of those exhibiting these symptoms. Morphological analysis confirmed the identity of Alternaria alternata in 26 representative isolates collected from various markets and bazaars. To examine genetic diversity or polymorphisms, start codon targeted (SCoT) markers were used. Species identification was based on the sequences of translation elongation factor 1-alpha (TEF 1-α), RNA polymerase second largest subunit (RPB2), and glyceraldehyde-3-phosphate dehydrogenase (GAPDH). SCoT 29 exhibited the highest amount of polymorphic amplicons, with 18 polymorphic bands scored when compared to the other six scoreable markers. The 26 representative isolates from various markets and bazaars were divided into four clades by SCoT 29. However, multilocus sequence analyses confirmed the identification of a single species, A. alternata. In terms of virulence and the impact of temperature on growth, representative isolates from four SCoT clusters were evaluated. Data suggests that SCoT markers can be used to evaluate virulence-based polymorphism in A. alternata; nonetheless, all clades showed comparable temperature responses, with 25 ◦C being the optimum. There was also no association between individual morphotypes and SCoT clade membership. Due to the lack of obvious signs on lemon fruits, producers, merchants, and consumers are unable to identify black rot, and the widespread presence of A. alternata in lemons may pose a significant risk that must be avoided at all costs.
Ameloriate Effect of Glucose Monohydrate on Nicotine Sulfate-induced Toxicity and Teratogenicity in Xenopus embryos: an Experimental Study
(Koszalin University of Technology, 2023) Pekmezekmek, Ayper Boğa; Emre, Mustafa; Tunç, Erdal; Sertdemir, Yaşar
It is well documented that nicotine causes low birth weight, preterm birth, pregnancy difficulties, lower fertility, inhibition of spermatogenesis, and decreased steroidogenesis and potassium channels conductance of Xenopus oocytes. Lung cancer is the most well-known adverse impact of nicotine. This work used a 96-hour FETAX test to examine how concurrent administration of glucose monohydrate modifies the effects of exposure to nicotine, nicotine sulfate, and/or glucose on ion channels and membrane potential in Xenopus leavis embryos at an early stage of development. In-vitro fertilised embryos were treated with nicotine and glucose alone or in combination for this aim, and the effects of those treatments were then assessed for potential teratogenic effects. At the conclusion of the FETAX technique, the ratios of healthy, abnormal, and dead embryos were calculated, and the length of embryos in each treatment group was assessed. The ratios of abnormal and dead embryos were considerably higher with nicotine treatment alone compared to controls. Compared to the results of the nicotine-alone treatment group, the ratio of aberrant embryos was marginally reduced by concurrent glucose and nicotine therapy. In contrast, the ratio of normal embryos was raised. Additionally, treatments with glucose, nicotine, and Nic+Glu significantly altered the resting membrane potentials of fertilised oocytes (p < 0.001). Our findings indicated that the simultaneous treatment groups that also received glucose had a protective impact on embryos. Such structured, more sophisticated research is required to confirm these findings.
Amino Acid Profile, Nutrients Content and Yield of Chickpea (Cicer Arietinum L.) Genotypes
(Scibulcom Ltd., 2015) Dogan, Y.; Doğan, Yusuf
Chickpea has significant amounts of all the essential amino acids except sulphur-containing types. It was found that chickpea is a rich source of protein and minerals. The experiments were conducted in a Randomised Complete Block Design with three replications 2013 and 2014 years in South-Eastern Turkey. A total of fifteen varieties, lines and populations were used as materials. In the study were investigated different parameters such as amino acids of protein, seed yield, protein and fat rate in seed, phosphorus, potassium, calcium, manganese, zinc, copper and iron contents and of seeds. The essential amino acid leucine (8.43 mg/100 g in 2013 and 8.59 mg/100 g in 2014) was found in highest concentration, followed by lysine (7.14 mg/100 g in 2013 and 7.27 mg/100 g in 2014) and phenylalanine (5.99 mg/100 g in 2013 and 6.07 mg/100 g in 2014) in the chickpea. Mineral composition of chickpea genotypes showed that they contribute sufficient amount of Ca, P, K, Cu, Zn and Mg in human diets to meet the recommended dietary allowance. According to the average of two years, the highest grain yield was obtained from Diyar-95 variety with 1618 kg ha–1, the lowest grain yield was obtained from M-1 local population with 1104 kg ha–1. © 2015, Scibulcom Ltd. All rights reserved.
Analysis of bioactive compounds using LC-ESI-MS/MS, cytotoxic, antimicrobial effects, and enzyme activities from Cyclotrichium origanifolium
(Wiley Online Library, 2022) Aktepe, Necmettin; Baran, Ayşe; Atalar, Mehmet Nuri; Baran, Mehmet Fırat; Keskin, Cumali; Taşkin, Abdullah; Yavuz, Ömer; Demirtaş, İbrahim; Oğuz, Ercan; Jahan, Israt
Cyclotrichium origanifolium is a medicinal plant belonging to the Lamiaceae family. In this study, phenolic content analysis, antimicrobial effects, and cytotoxic effects of extracts of C. origanifolium were investigated. In the extracts, phenolic compound analysis by the liquid chromatography–electrospray ionization– tandem mass spectrometry method, antimicrobial effect by the minimum inhibition concentration method, and cytotoxic effect on human dermal fibroblasts (HDF), glioblastoma cell (U87), ovarian adenocarcinoma cell (Skov-3), and human colorectal adenocarcinoma cell (CaCo-2) cancer cell lines were investigated. Cytotoxicity analyses were performed by the MTT method. In addition, the GST and AChE enzyme activities of the extracts were also measured. Around 18 compounds were detected in both the methanol and ethanol extract. It was found that the best antimicrobial effect on Gram-negative Pseudomonas aeruginosa was on methanol extract, while the ethanol extract was on Candida albicans fungus (respectively, 2.50mg/ml, 5.0 μg/ml). A 500μg/ml of methanol extract has been shown to have cytotoxic activity high effect on HDF cells. GST and AChE activity were found to decrease in a concentration-dependent manner.

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