WoS İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.12514/3595

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Citation - WoS: 8
Citation - Scopus: 8
Hydrogel burn dressing effectiveness in burn pain
(Elsevier Sci Ltd, 2024) Celik, Enes; Akelma, Hakan
Severe burns are painful and dramatic injuries. Studies show that pain is underestimated and often not adequately treated. This study aims to evaluate the analgesic efficacy of hydrogel burn dressing and silver sulfadiazine, which are two agents commonly used in first-aid dressings for burn patients. This study, designed as a prospective, observational, and cross-sectional study. Study included 64 pediatric patients admitted to our burn center between 01.03.2020 and 01.09.2020 who were examined by our burn service after their first treatment in the emergency dressing room. Two groups of patients were included in the study. Pain level was assessed in the dressing room before and 10 min after the procedure using the Visual Analog Scale and FLACC (Face, Legs, Activity, Cry, Consolability) pain assessment scales.During the study period, Burnaid (R) was applied to 62.5% of patients (40 patients) and silver sulfadiazine to 37.5% (24 patients). In terms of pain scores, pre-dressing FLACC values were higher in Group B (p = 0.039); post-dressing VAS and FLACC values were significantly lower in group B (p 0.001; p 0.001). In terms of additional analgesia, we found more patients in Group S received analgesics (p 0.001).We believe that its effect on burn wound pain is superior to that of silver sulfadiazine.(c) 2023 Elsevier Ltd and ISBI. All rights reserved.
Citation - WoS: 5
Citation - Scopus: 11
Determinants of Mediation Success in Post-Conflict Bosnia: A Focused Comparison
(Routledge Journals, Taylor & Francis Ltd, 2015) Zenelaj, Reina; Beriker, Nimet; Hatipoglu, Emre
The main goal of this study is to look at factors determining mediation success in post-conflict environments. More specifically, the authors focus on the level of involvement of the mediator in a post-conflict setting and argue that relational mediation strategies should fare better in such environments. A most similar systems comparison of the European Union/USA and Turkish mediation efforts in Bosnia-Herzegovina, both of which started in October 2009, renders support for the authors' argument. Their analysis of these two cases suggests that Turkey's relational mediation strategy delivered concrete outcomes in post-Dayton Bosnia compared to the structural intervention style adopted by the European Union/USA. The authors conclude that a relational mediation strategy facilitates the achievement of constructive solutions by helping third parties to make broader assessments of the conflict situation, and by offering flexible options in issue selection and process design.
The Role of Statins in Modulating Subclinical Inflammatory Markers in Coronary Slow Flow Phenomenon
(Lippincott Williams & Wilkins, 2025) Demirci, Murat; Mustafayev, Urfan; Atas, Halil; Oguz, Mustafa; Kilic, Raif; Sunbul, Murat
Coronary slow flow phenomenon (CSFP) is characterized by slow coronary blood flow in the absence of significant stenosis, and its pathophysiology is associated with endothelial dysfunction, microvascular abnormalities, and inflammation. This study aimed to investigate the effects of statin therapy on subclinical inflammatory markers in CSFP patients. This retrospective cohort study included patients diagnosed with CSFP by using coronary angiography. The patients were divided into statin and control groups based on the initiation of statin therapy. Inflammatory markers, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune-inflammation index (SII), and systemic inflammation response index (SIRI) were assessed at baseline and 3 months later. At baseline, NLR, PLR, SII, and SIRI levels were comparable between the 2 groups. After 3 months, these markers were significantly lower in the statin group. In the statin group, the NLR, PLR, SII, and SIRI levels significantly decreased from baseline, whereas no significant changes were observed in the control group. The reduction in inflammatory marker levels was more pronounced in patients receiving high-dose statins. Statin therapy is associated with reduced subclinical inflammation in CSFP, supporting the inflammatory basis and therapeutic value of statins.
Effects of Carvacrol on Oxidative Stress and Fibrosis in Streptozotocin-Induced Diabetic Nephropathy: Histological, Gene Expression, and Biochemical Insights
(MDPI, 2025) Canbaz, Halime Tuba; Sozen, Mehmet Enes; Cinar Ayan, Ilknur; Savas, Hasan Basri; Canbaz, Furkan Adem; Cuce, Gokhan; Kalkan, Serpil
Diabetes mellitus (DM) leads to renal damage through oxidative stress. Carvacrol (CAR), a monoterpenoid phenol, possesses anti-inflammatory and antioxidant properties. We investigated the potential effects of CAR on histological, gene expression, and biochemical parameters in a rat model of DM. Four groups were created: group 1, control; group 2 (n = 9), DM; group 3 (n = 9), DM + dimethyl sulfoxide (DMSO); and group 4 (n = 9), DM + CAR. DM was created by injecting streptozotocin (STZ). CAR (20 mg/kg) was prepared through dissolution in 0.1% DMSO. CAR and 0.1% DMSO were administered daily for 4 weeks to groups 4 and 3, respectively. At the end of this study, urea, creatinine, paraoxonase-1 (PON-1), and arylesterase (ARES) were measured in serum samples. Histopathological changes and expression of Nuclear factor erythroid 2-related factor 2 (Nrf-2) in renal tissues were assessed. Immunohistochemical(ihc) staining and RT-qPCR analysis were performed to evaluate apoptosis, focusing on Bax and Bcl-2gene expression. Masson's trichrome(MT) staining and RT-qPCR analysis of COL1A1 and COL3A1 mRNA levels were used to assess fibrosis. Increased urea and creatinine levels in DM were significantly decreased after CAR administration. CAR application also improved reduced levels of PON 1 and ARES, which are associated with diabetes. Both immunohistochemistry and RT-qPCR analyses revealed that CAR therapy mitigated the diabetes-induced elevation in Bax and reduction in Bcl-2 expression. CAR treatment improved histopathological findings and renal Nrf-2 immunofluorescence(if) intensity. Furthermore, gene expression analysis demonstrated that COL1A1 and COL3A1 were upregulated in DM, while CAR administration downregulated them. In conclusion, CAR has a protective role in decreasing renal impairment linked to DM by regulating Bax and Bcl-2 levels and rectifying histological damage.
Retrospective Evaluation of Patients Admitted to the Intensive Care Unit Due to Obstetric Reasons in Terms of Maternal Near-Miss, a Five-Year Case-Control Study
(BMC, 2025) Erdem, Ozgur; Oglak, Suleyman Cemil; Toktas, Izzettin; Baydemir, Seher; Yosunkaya, Ahmet; Erdem, Ali
Background Maternal Near-Miss (MNM) has become globally recognized as an indicator of pregnancy, birth and the first 42 days of postpartum care services. The World Health Organization has taken a new approach to detail and better analyze maternal deaths. The clinic-based criteria to evaluate maternal care and the quality of related care services have been developed. Methods This is a retrospective case-control study that was conducted in a tertiary hospital. In the study, the medical files of all patients admitted to the intensive care unit during the five-year period between 2018 and 2022 were examined. All patients who met the MNM criteria of WHO during pregnancy, birth and puerperium were included in the case group of the study. Meanwhile, the participants in the control group were selected from mothers who gave birth in the same hospital between August 15 and October 31, 2023 and did not develop any complications during puerperium, using the systematic sampling method. Data collection was performed using an interviewer-administered structured questionnaire and data abstraction. Results In this five-year period, 198 mothers were diagnosed with MNM. In our study, the prevalence of MNM was found as 218/100.000. The most common laboratory changes that met the MNM criteria were elevated lactate levels (38.89%), acidosis (24.24%) and acute thrombocytopenia. Patients were most frequently admitted to the intensive care unit due to hemorrhage (23.74%), placental abruption (18.18%), pre-eclampsia (15.66%) and cesarean Sect. (10.10%), respectively. The frequency of co-morbidities (Diabetes mellitus, Hypertension, Asthma, Hypothyroidism, etc.) in patients diagnosed with MNM (n = 48; 26.67%) was found to be 5.5 times that of the control group (n = 25; 6.20%) (p < 0.001). Conclusions It can be said that co-morbidities directly affect the course of motherhood. the education level and family income were found higher in the MNM group compared to the control group. In this regard, the results of our study differ from the studies in the literature in terms of the effects of the education level of mothers and the economic status of families. The effects of socioeconomic and cultural factors on MNM may vary.
Citation - WoS: 10
Citation - Scopus: 11
Comparison of Lipid Contents and Fatty Acid Profiles of Freshwater Fish from the Atatürk Dam Lake
(Walter de Gruyter GmbH, 2016) Bashan, Mehmet; Kacar, Semra
Objective: The objective of the study was to examine the lipid levels, fatty acid profiles (especially EPA and DHA which play an important role in the prevention of a wide variety disorders such as; coronary heart disease, hypertension, rheumatoid arthritis, breast and colon cancer, Alzheimer disease, inflammation and autoimmune disorders) and n-3/n-6 ratio of some freshwater fish in Ataturk Dam Lake. Methods: Samples of 12 fish species from the Ataturk Dam Lake (Turkey) were investigated for their fat content and fatty acid composition (Aspius vorax, Carasobarbus luteus, Carassius gibelio, Liza abu, Acanthobrama marmid, Barbus xanthopterus, Cyprinion macrostomum, Carassius auratus, Calcalburnus mossulensis, Capoeta trutta, Mastacembelus simack, Chondrostoma regium). Total lipids were extracted with 10 ml of chloroform-methanol (2/1v/v). Samples containing muscle lipid were transesterified with acidified methanol. The fatty acid methyl esters were extracted with hexane. Fatty acids were detected by gas chromatography (GC). Results: The lipid content of species ranged from 0.78% to 2.51%. The highest lipid content was found in female C. trutta (2.51%). The major SFAs were myristic acid (C14:0), palmitic acid (C16:0) and stearic acid (C18: 0). Oleic acid (C18:1 n-9) and palmitoleic acid (C16:1 n-7) were the prominent MUFA. The dominant PUFAs were linoleic acid (LA, C18:2 n-6), linolenic acid (ALA, C18:3 n-3), arachidonic acid (AA, C20:4 n-6), eicoesapentaenoic acid (EPA, C20: 5 n-3) and docoesahexaenoic acid (DHA, C22:6 n-3). The ratio of n-3/n-6 PUFAs ranged from 1.22 to 4.71. Conclusion: In this study, the fatty acid composition varied between different species In addition, the highest n-3/n-6 ratios were observed in female C. trutta, C. mossulensis, C. regium and A. vorax. Therefore, these species are economically important fish considering n-3 fatty acids and n-3/n-6 ratios.
Citation - Scopus: 4
Evaluation of Breastfeeding Behaviors and Complementary Feeding Practices of Turkish and Syrian Refugee Mothers
(Soc Argentina Pediatria, 2023) Orhan, Ozhan; Elci, Huseyin
Objectives: The purpose of this study was to compare breastfeeding and related factors (age, level of education, age at first pregnancy, etc.), and complementary feeding practices between Syrian refugee and native Turkish mothers.Material and methods: This descriptive-comparative study examined the nutritional characteristics of infants aged 9 to 60 months whose mothers were Turkish or Syrian refugees who attended Kiziltepe Results: 204 mothers (126 Turkish and 78 Syrian) who had a child aged 9-60 months were included. The average age of the mothers was 27.60 & PLUSMN; 5.17 years for Turkish citizens and 28.91 & PLUSMN; 5.62 for Syrian refugees, without significant difference between the two groups (p: 0.091). Postpartum breastfeeding was 91.3% and breastfeeding duration was 12 (0-24) months in Turkish citizens; in Syrian refugees, breastfeeding was 84.6% and average breastfeeding time was 9 (0- 24) months (respectively, breast milk intake p: 0.144, uptake time p: 0.161; no statistical difference). Breastfeeding training was received by 23.8% of Turkish citizens and 5.1% of Syrian refugees; there was a significant difference between the two groups (p: 0.001).Conclusion: In refugee groups, infant and maternal nutrition practices are disrupted. Working in conjunction with local and international organizations and state agencies that give help to refugee groups, the appropriate interventions, initiatives, supports, and awareness-raising activities would strive to improve practices in mother and baby nutrition and narrow gaps.
Automated Mucormycosis Diagnosis from Paranasal CT Using ResNet50 and ConvNeXt Small
(MDPI, 2025) Toprak, Serdar Ferit; Dedeoglu, Serkan; Kozan, Gunay; Ayral, Muhammed; Can, Sermin; Turk, Omer; Akdag, Mehmet
Purpose: Mucormycosis is a life-threatening fungal infection, where rapid diagnosis is critical. We developed a deep learning approach using paranasal computed tomography (CT) images to test whether mucormycosis can be detected automatically, potentially aiding or expediting the diagnostic process that traditionally relies on biopsy. Methods: In this retrospective study, 794 CT images (from patients with mucormycosis, nasal polyps, or normal findings) were analyzed. Images were resized and augmented for training. Two transfer learning models (ResNet50 and ConvNeXt Small) were fine-tuned to classify images into the three categories. We employed a 70/30 train-test split (with five-fold cross-validation) and evaluated performance using accuracy, precision, recall, F1-score, and confusion matrices. Results: The ConvNeXt Small model achieved 100% accuracy on the test set (precision/recall/F1-score = 1.00 for all classes), while ResNet50 achieved 99.16% accuracy (precision approximate to 0.99, recall approximate to 0.99). Cross-validation yielded consistent results (ConvNeXt accuracy similar to 99% across folds), indicating no overfitting. An ablation study confirmed the benefit of transfer learning, as training ConvNeXt from scratch led to lower accuracy (similar to 85%) Conclusions: Our findings demonstrate that deep learning models can accurately and non-invasively detect mucormycosis from CT scans, potentially flagging suspected cases for prompt treatment. These models could serve as rapid screening tools to complement standard diagnostic methods (histopathology), although we emphasize that they are adjuncts and not replacements for biopsy. Future work should validate these models on external datasets and investigate their integration into clinical workflows for earlier intervention in mucormycosis.
The Sea in the Novels Aganta Burina Burinata by the Fisherman of Halicarnassus and Sail and Storm by Hanna Mina
(Sirnak Univ, 2021) Alsibli, Ibrahim
This research aims to explain the sea image in Aganta Burina Burinata by the Fisherman of Halicarnassus and Sail and Storm by Hanna Mina in a comparative way. In this sense, the American Literature School approach, which shows the aesthetics of the similarities and differences between the sea images in the two narratives, was taken as a basis in this study. The reason for this is that the American school focuses on the aesthetic cooperations between the literatures of different nations and does not attach importance to the issues of influence. The research is in four parts, the first of which is the narrative language and the role of the sea image in the fictional depiction of words, sentences, and narrative passages in two novels, and the forms of conflict between man and nature. The second part discusses the role of the land in shaping the sea territory while analyzing the existence of closed and open spaces and the effect of open spaces in the two novels. The focus is on the ability of the narrative style to express the sea territory where the events in both novels take place. The third part compares the techniques of the narrative time, the role of flashbacks in shedding light on the background of the characters, and the techniques such as foreshadowing, which means predicting some future events to arouse the reader's curiosity. The fourth part focuses on the comparison of the sea vision from the perspectives of the protagonists in the novels Purinata and Sail and Storm. This article reveals the similarity of the narrative in the two novels in terms of describing the lives of sailors, dockers and fishermen, and also contributed to the understanding of history. The research showed th analyzing at the open places were more present than the closed ones, and the sea appeared as a haven for the hero of the two novels to resort to escape from the world of land and its contradictions and conflicts that occur in it as a result of human greed, and their desire to adapt nature to achieve their goals, while the sea was a field for self-search, dreaming, and contemplation.
Citation - WoS: 7
Citation - Scopus: 10
Is There Any Effect of Non-Suitable Pull Technique in Back & Leg Dynamometers on the Leg Strength Test Results
(Carbone Editore, 2019) Aslan, Cem Sinan; Karakulak, Izzet; Sahin, Fatma Nese; Eyuboglu, Ender
Introduction: Dynamometers are valid and reliable test instruments that have been used for many years to measure strength. However, there are excessive differences in leg strength scores in different studies with similar groups. This situation suggests a non-conformity to testing procedures occurred during the practice of the tests. The purpose of this study was to determine the effect of non-suitable pulling technique on the leg strength test results. Materials and methods: A total of 127 healthy subjects (24 female athletes and 41 male athletes, 22 sedentary females and 40 sedentary males) were included in the study. A back & leg Dynamometer was used to determine the leg strength of the participants. The participants pulled up the dynamometer's grab handle with and without contact with their upper leg. Results: The results showed that there was a significant difference (p=0.000) between contacted and non-contact pulling trials of all participants. The percentage difference of leg strength between contacted and non-contact pull was 51.69% (43.25 kg) for female athletes, 54.78 (73.46 kg) for male athletes, 5631% (37.52 kg) for sedentary females, and 50.69% (65.55 kg) for sedentary males. Conclusion: There were significant differences between contacted and non-contact pull trials. It was determined that during the pulling phase if the dynamometer's grab-handle contacted the upper leg of a subject, the strength measurement's score increased considerably. In this case, it can be said that non-suitable pulling technique in the "back & leg dynamometers" affects the leg strength test scores.
Citation - WoS: 18
Citation - Scopus: 14
In-Vitro Antioxidant, Cytotoxic, Cholinesterase Inhibitory Activities and Anti-Genotoxic Effects of Hypericum Retusum Aucher Flowers, Fruits and Seeds Methanol Extracts in Human Mononuclear Leukocytes
(Iranian Journal of Pharmaceutical Research, 2017) Keskin, C.; Keskin, Cumali; Aktepe, N.; Aktepe, Necmettin; Yükselten, Y.; Asuman,; Boğa, M.; 21.02. Department of Medical Services and Techniques / Tıbbi Hizmetler ve Teknikleri Bölümü; 09.01. Department of Nursing / Hemşirelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 21. Vocational School of Health Services / Sağlık Hizmetleri Meslek Yüksekokulu; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
The present study investigates the antioxidant, anticancer, anticholinesterase, anti-genotoxic activities and phenolic contents of flower, fruit and seed methanol extracts of Hypericum retusum AUCHER. The amounts of protocatechuic acid, catechin, caffeic acid and syringic acid in methanol extracts were determined by HPLC. Total phenolic content of H. retusum seed extract was found more than fruit and flower extracts. The DPPH free radical scavenging activity of flower and seed methanol extracts showed close activity versus BHT as control. Among three extracts of H. retusum only flower methanol extract was exhibited considerable cytotoxic activities against to HeLa and NRK-52E cell lines. Moreover, seed methanol extract showed both acetyl and butyrl-cholinesterase inhibitory activity. The highest anti-genotoxic effects were seen 25 and 50 μg/mL concentrations. In this study, the extracts showed a strong antioxidant and anti-genotoxic effect. The seed extract was more efficient- than extracts of fruit and flowers. Our results suggest that the antioxidant and anti-genotoxic effects of extracts depend on their phenolic contents. Further studies should evaluate the in-vitro and in-vivo the benefits of H. retusum seed methanol extracts. © 2017 by School of Pharmacy.
Citation - WoS: 22
Citation - Scopus: 19
Effect of Silver Nanopowder Addition on Mechanical Properties of Silver-Copper Alloy Used in the Jewellery Industry
(Sage Publications Ltd, 2025) Adin, Hamit; Akgul, Sabahattin; Adin, Mehmet Sukru
In this research, silver nanopowder (at rates of 0%, 0.5%, 1%, 1.5% and 2%) was added to 925-carat silver-copper alloy used in manufacturing silver jewellery to increase its durability and to observe its mechanical properties occurred. In this context, different mechanical tests (tensile, bending and hardness) were performed on exclusively produced silver-copper alloys. Moreover, mechanical simulation tests were conducted via ANSYS software using the data obtained from the experimental results. In the tensile tests, it was observed that the use of nanopowder at the rates of 0.5% and 1% positively affected the tensile strength and strain values, while when the nanopowder rate exceeded 1%, both parameters were negatively affected. According to tensile test results, the ductility of the alloy material decreases as the rates of nanopowder addition rise. In the bending tests, it was observed that the addition of 1% nanopowder increased the bending strength significantly; however, other addition rates had a negative effect. Hardness measurements showed that the 1% nanopowder ratio had a much higher effect (in terms of increasing the hardness value) on the hardness value than 0.5%, 1.5% and 2% nanopowder ratios. In order to verify the numerical analysis model, the results of both experimental and numerical analyses were compared. The success of numerical modelling was found to be similar to 96% in terms of both tensile strength and displacement. Many methods are used in the jewellery industry, especially in silver jewellery. To easily shape the material to be used in filigree, repousse, and tattoo techniques, the material must be somewhat soft and pliable. Therefore, if production is carried out using these techniques, it is not advisable to add large amounts of nanopowder to the alloy. Furthermore, adding quite low amounts (0.1%, 0.5% etc.) of nanopowder to the silver-copper alloy will provide efficient results in shaping-based production techniques.
Citation - WoS: 1
Citation - Scopus: 1
Confounding Factors in the Tear Break-Up Time Test. Influence of Sequential Measurements
(Taylor & Francis Ltd, 2025) Acet, Yakup; Dag, Yasar
Clinical relevance The tear break-up time (BUT) test is important in diagnosing and monitoring tear film stability, and understanding potential changes in tear film dynamics during repeated measurements could improve the accuracy and reliability of the test in clinical practice. Background The study aimed to examine the changes in BUT value caused by subsequent measurements made in BUT test. Methods A total of 120 female participants were divided into groups (30 individuals each). Participants were divided into four groups based on the interval between two non-invasive tear break-up time (NI-BUT) tests: Group 1 (1-minute interval), Group 5 (5-minute interval), Group 10 (10-minute interval), and Group 15 (15-minute interval). The first NI-BUT test was called Initial NI-BUT (NI-BUT(I)), and the second test was called Subsequent NI-BUT (NI-BUT(S)). The first BUTvalue (BUT1st), the second BUT value (BUT2nd), the third BUT value (BUT3rd), the fourth BUT value (BUT4th), the fifth BUT value (BUT5th), and the average value of the first three BUTs (BUTA3) were compared between the NI-BUT(1) and NI-BUT(S) tests. Results Participant ages ranged from 18 to 36 years, with a mean of 25.1 +/- 3.2 years. The mean values of BUT1st, BUT2(nd), BUT3(rd), BUT4(th), BUT5(th), and BUTA3 in the NI-BUT(I) test were statistically significantly shorter than those in the NI-BUT(S) test for all groups (p < 0.05). The changes in the parameters were statistically significantly greater in Group 1 compared to the other groups (p < 0.05). Conclusions Subsequent measurements cause increased BUT values. The longer the interval between two measurements, the smaller the differences between the subsequent measurements. When performing the BUT test, a single measurement should be preferred if possible. If the clinician finds the results of a single measurement unsatisfactory and wishes to consider the average of multiple measurements, the interval between tests should be longer than 15 minutes.
Skin Lesion Classification Using Focal Modulation Networks
(John Wiley and Sons Inc, 2025) Zan, H.
The automatic classification of dermoscopic images is essential for the early diagnosis and treatment of skin cancer. However, this task remains challenging due to high visual similarity among lesion types, variations in lesion appearance across progression stages, and the presence of artifacts in the images. While deep learning-based approaches have outperformed traditional machine learning methods, many existing models are computationally intensive and offer limited interpretability. These limitations hinder their integration into clinical workflows where efficiency and transparency are critical. In this study, I propose a framework based on focal modulation networks (FMNs) for skin lesion classification. FMNs are designed to efficiently capture both local and global features, addressing the limitations of transformer-based models in processing high-resolution medical images. I evaluate four FMN variants, namely, Tiny, Small, Base, and Large, on three public datasets: ISIC 2017, ISIC 2018, and ISIC 2019. The highest classification accuracy was obtained on ISIC 2019 with 97.8%, followed by 96.4% on ISIC 2018, and 88.1% on ISIC 2017. These results match or exceed those reported in several previous studies. Additionally, FMNs offer model interpretability through modulator visualization. Overall, the proposed method provides an accurate, efficient, and transparent solution for automated skin lesion classification. © 2025 The New York Academy of Sciences.
Evolving Policies of the EU Towards Israeli-Palestinian Conflict: Changing Actor Identities and Geostrategic Interests
(Seta Foundation, 2025) Acar, Necmettin; Kızılkan, Zelal
From the 1980s onwards, the EU took a balanced approach to the Israeli-Palestinian conflict. In the last two decades, the EU has abandoned its role as a normative and neutral player. It appeared to address the Israe- li-Palestinian conflict within the context of security. On this basis, the paper aims to assess changing policies of the EU towards the Israeli-Palestinian conflict since the early 1970s. By revisiting constructivist theories, the study attempts to find out the role of the identities in the EU’s policies toward the Israeli-Palestinian conflict. It concludes that the shift in the identities of the major political actors from the Palestine Liberation Organization to Hamas led to the reformulation of its policy toward Israeli-Palestinian conflict.
Chemometric Differentiation of Organic Honeys From Southeastern Türkiye Based on Free Amino Acid and Phenolic Profiles
(MDPI, 2025) Gurbuz, Semra; Kivrak, Seyda
Verifying the geographical origin of honey is crucial for its market value and for preventing fraudulent practices. This study aimed to characterize the chemical profiles of organic honeys from three distinct regions in Southeastern T & uuml;rkiye-& Scedil;& imath;rnak Fara & scedil;in, Siirt Merkez, and Siirt Pervari-to establish a robust method for geographical authentication. A total of 51 multifloral honey samples were analyzed. The concentrations of 20 free amino acids (FAAs) and 16 phenolic compounds were quantified using (UPLC-ESI-MS/MS). The resulting data were subjected to both an unsupervised (PCA, CA) and supervised (PLS-DA, RF, SVM) chemometric analysis to identify biochemical markers for each region. The results revealed a distinct chemical fingerprint for each region. Based on the FAA profiles, the PLS-DA method provided the best overall classification, achieving an excellent discrimination with a total accuracy of 94.1% in the & Scedil;& imath;rnak Fara & scedil;in honeys. For the phenolic compound profiles, the RF method achieved the highest correct classification rate for & Scedil;& imath;rnak Fara & scedil;in honeys at 88.2%. This study demonstrates that an integrated approach, combining FAA and phenolic profiles with supervised chemometric methods, provides a successful and reliable model for determining the geographical origin of these multifloral honeys.
Comparison of the Gonadoprotective Functions of Nigella Sativa Oil, Metformin and Vitamin E on Streptozotocin-Induced Diabetic Testis
(Edizioni Minerva Medica, 2025) Kaya, Seval; Seker, Ugur; Ozmen, Mehmet F.; Ayaz, Hayat; Erdogan, Gamze; Nergiz, Yusuf
BACKGROUND: Changes in blood glucose levels in DM cause many complications. We aimed to make a detailed comparison study on the protective effects of Nigella sativa oil, metformin, and vitamin E on the histopathologic effects of diabetes on the male reproductive system. METHODS: In the experiment, 30 rats were divided equally into 5 groups: Control, DM, DM+NS, DM+M and DM+E. To induce diabetes in the experimental groups, a one-time injection of 45 mg/kg Streptozotocin was administered. Rats with blood glucose levels above 250 mg/dl were included in the experiment. The experiment period lasted 8 weeks. Weekly body weight of the rats, reproductive organ weights at the end of the experiment, spermatologic data, immunohistochemical staining, TUNEL assay staining and morphometric evaluation were performed. RESULTS: According to Johnsen Biopsy Score and Seminiferous Tubule diameter data, the DM+NS group had similar results to the control group, indicating that Nigella sativa oil preserved the seminiferous tubule diameter structure better than vitamin E and metformin. There were head, neck and tail defects in the diabetes group. Based on the results of the applications carried out to evaluate apoptosis and proliferation in testicular tissue, it can be concluded that the treated diabetic groups, especially the Nigella sativa oil, improved the structure of spermatogenic tubules and also reduced the number of apoptotic cells, as shown by the results of the TUNEL test (P<0.05). CONCLUSIONS: We think that Nigella sativa oil is more effective on the mechanism of diabetes than other active substances and regulates metabolic changes and may be an effective therapeutic agent for diabetes treatment.
Citation - WoS: 8
Citation - Scopus: 8
Enhancing Vehicle Fault Diagnosis Through Multi-View Sound Analysis: Integrating Scalograms and Spectrograms in a Deep Learning Framework
(Springer London Ltd, 2025) Akbalik, Ferit; Yildiz, Abdulnasir; Ertugrul, Omer Faruk; Zan, Hasan
This study presents a comprehensive framework for vehicle fault diagnosis using engine sound signals, leveraging deep learning models and a multi-view approach. Traditional methods for vehicle fault diagnosis often rely on the expertise of mechanics or diagnostic tools, which can be costly, time-consuming, and may not always provide accurate results. To address these limitations, we propose CarFaultNet, a multi-view model that processes both scalograms and spectrograms simultaneously to capture complementary information from these time-frequency representations. Our approach incorporates transfer learning with pretrained convolutional neural networks, including AlexNet, GoogLeNet, ShuffleNet, SqueezeNet, and MobileNet v2, as well as CarFaultNet, which combines two MobileNet networks. The results demonstrate that CarFaultNet outperforms traditional machine learning methods and single-view deep learning models, achieving a precision of 95.32%, recall of 94.83%, F1-score of 94.99%, and accuracy of 95.00%. Class activation mapping visualizations provide valuable insights into the model's decision-making process, highlighting the regions of the input images that are most influential for the classification of different vehicle faults. By leveraging a large, diverse dataset encompassing various vehicle models and real-world operating conditions, our approach addresses the drawbacks of previous studies and demonstrates the potential of deep learning for practical and effective vehicle fault diagnosis.
Postharvest Management of Neoscytalidium Dimidiatum Using GRAS Potassium Salts
(Springer, 2025) Yildirim, Elif; Dervis, Sibel; Erper, Ismail; Dalbasti, Nese; Ozer, Goksel; Turkkan, Muharrem
Neoscytalidium dimidiatum is an emerging fungal pathogen of increasing phytosanitary concern due to its wide host range, aggressive postharvest behavior, and expanding geographical distribution, yet comprehensive evaluations of safe, effective control measures such as potassium salts remain limited. This study investigated eight potassium salts-acetate, benzoate, bicarbonate, carbonate, citrate, metabisulfite, phosphate, and sorbate-compared to three commercial fungicides (imazalil, thiophanate-M, and tebuconazole + fluopyram) for their antifungal efficacy against N. dimidiatum in vitro (culture assays) and in vivo (postharvest apple fruit trials). In vitro assessments revealed potassium metabisulfite (EC50 = 4.4 x 10-5 g mL-1) and potassium sorbate (EC50 = 9.0 x 10-5 g mL-1) as the most effective salts, demonstrating antifungal activity comparable to commercial fungicides imazalil, tebuconazole + fluopyram, and thiophanate-M. These two potassium salts consistently inhibited mycelial growth, arthrospore germination, and germ tube elongation even at the lowest tested concentrations, while other potassium salts showed variable and generally lower efficacy. In vivo experiments on apple fruits further confirmed these findings, with potassium metabisulfite providing up to 92.48% lesion reduction in protective applications at 1.0 x 10-2 g mL-1, comparable to thiophanate-M (93.81%) and tebuconazole + fluopyram (98.47%). Notably, potassium metabisulfite outperformed imazalil, which only reached 61.36% protection at its highest concentration. In curative applications, potassium metabisulfite and phosphate achieved approximately 87% lesion reduction at 1.0 x 10-2 g mL-1, matching the performance of commercial fungicides at their recommended concentrations. Interestingly, low concentrations of potassium benzoate and carbonate increased lesion development in both protective and curative applications. These findings suggest potassium metabisulfite as a promising alternative to conventional fungicides for controlling N. dimidiatum infections, with potential applications in sustainable disease management strategies.
Evaluation of Some Corn Genotypes as a Second Crop by Trait (GT) Biplot Method
(Natl information Documentation Cent, Acad Scientific Research & Technology, 2025) Dogan, Serap; Acibuca, Veysi; Dogan, Yusuf
IT is extremely important to grow more than one product in a production season to obtain the maximum income per unit area. Maize is one of the most suitable crops for the second product. This research was carried out in Tilkitepe village of Artuklu district of Mardin province in the 2021 growing season to determine the second crop conditions in the borders of Mardin province using hybrid cultivars with different characteristics. The study was conducted according to a randomised block design with three replications. The data obtained from the traits investigated in this study were subjected to an analysis of variance and interpreted using the GT biplot technique. Significant differences at the 1% level (p<0.01) were found between the genotypes in terms of the traits studied, except for the protein ratio. In the results of the study; plant height (PH) varied between 209-254 cm, height of first ear (HFC) between 59.4-87.7 cm, ear length (CL) between 17.7-21.7 cm, number of rows on ear (NRC) between 39.2-43.8 pieces, 100 grain weight (100 GW) between 30. 3-43.5 g, cob weight (CW) between 186-254 g, number of grains on the cob (NGC) between 584-696 pieces, hectolitre weight (HW) between 75.1-82.2 kg/hl, protein ratio (PR) 6.6-9.5%, grain yield (GY) between 9629-13220 kg/ha. According to the results and biplot graphs, Dekalb-6050(G39) was the most suitable genotype among the genotypes based on grain yield and traits as a second crop. As a result, this variation showed that the maize cultivar had good results as a second crop under the Mardin condition. Therefore, the Dekalb-6050(G39) genotype can be recommended for cultivation as a second crop in the following years under Mardin conditions.

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