Araştırma Çıktıları | TR-Dizin | WoS | Scopus | PubMed

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2023-2024 Excavations at Boğaziye Höyüğü: a Recently Discovered Mound Settlement in the Upper Khabur Region
(Istanbul Univ, 2025) Gene, Bulent; Sahin, Muaviye; Isik, Senem; Abakay, Ayda; Kaya, Semsihan; Konyar, Erkan; Tan, Armagan
Boğaziye Höyük lies at the northwestern end of the vast and fertile Upper Khabur Region, which stretches along the southern foothills of the Kašiari Mountains. Material culture remains unearthed at the mound by two seasons of excavations (2023-2024) shows significant similarities to assemblages known from other Upper Khabur sites. Our excavations in Trenches BE18-BE17 and BF18 on the northern slope of the mound focused on revealing the stratigraphic sequence in this area. Architectural remains of Building Levels I and II and finds from these contexts in Trench BE18 are dateable to the mid-3rd millennium BC. In Trench BE17, Building Level I also revealed finds that can be dated to the 3rd (especially mid-3rd) millennium BC, and in Trench BF18, ceramic sherds dateable to the 3rd millennium BC were found in Building Level III. This article presents new findings from Boğaziye Höyük and discusses their significance in comparison with the results of surveys and excavations in the Upper Khabur Region, which have continued increasingly since the mid-1930s. We evaluate the significance of Boğaziye Höyük as a regional center within the Upper Khabur basin, and we elucidate its habitation sequence and building levels in the light of our recent excavations. Based on a comparative evaluation of its material culture remains within a regional perspective, we contextualize Boğaziye Höyük in relationship to the cultural horizons of the early and mid-3rd millennium BC in the Upper Khabur Valley.
6. Sınıf Türkçe Dersinde Yaratıcı Yazma Yaklaşımının Öğrencilerin Yazmaya Yönelik Tutumlarına ve Yazma Becerilerine Etkisi
(T.C. Milli Eğitim Bakanlığı, 2023) Akto, Akif; Kıran Ölmez, Ela; Bindak, Recep; 02.04. Department of Educational Sciences / Eğitim Bilimleri Bölümü; 02. Faculty of Letters / Edebiyat Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Bu araştırma, 6. sınıf Türkçe dersinde yaratıcı yazma yaklaşımının öğrencilerin yazmaya yönelik tutumlarına ve yazma becerilerine etkisini tespit etmek amacıyla yapılmıştır. Araştırma 2021-2022 eğitim-öğretim yılı 2. Dönem içerisinde Mardin ili Artuklu ilçesine bağlı bir ortaokulun 6. Sınıfında okuyan 20 öğrenciyle yürütülmüştür. Araştırmada veri toplama aracı olarak yarı deneysel yöntemle tek grup ön test/son test modeli uygulanmıştır. Etkinlikler haftada iki saat olmak üzere 8 hafta boyunca toplam 16 saat uygulanmıştır. Araştırmada veri toplama aracı olarak deneysel işlem öncesinde ve sonrasında yazmaya yönelik tutum ölçeği kullanılmıştır. Deneysel çalışma boyunca yaratıcı yazma etkinlik yaprakları kullanılmıştır. Veri toplama araçları çalışma grubunda ön test ve son test olarak uygulanmıştır. Çalışma kapsamında nicel verilerin analizinde SPSS 22.0 istatistik paket programı kullanılmıştır. Araştırma boyunca uygulanan yaratıcı yazma çalışmaları, betimsel analiz yöntemiyle analiz edilmiştir. Araştırmada şu sonuçlara ulaşılmıştır: • Yaratıcı yazma çalışmalarının neticesinde elde edilen son test puanları ön test puanlarına göre yüksek çıkmıştır. Çalışma grubunun ön test ve son test puanları eşleştirilmiş t-testi analizi uygulanarak karşılaştırılmış ve ön test ve son test puanları arasında anlamlı bir farklılık olduğu bulunmuştur. Buna göre Türkçe derslerinde uygulanan yaratıcı yazma uygulamalarının öğrencilerin yazma tutum ve becerilerinde anlamlı bir artışa neden olduğu tespit edilmiştir (p<0,05). • Betimsel analiz yöntemi sonucunda elde edilen verilere göre yaratıcı yazma çalışmaları, öğrencilerin yazma tutumlarını ve yazma becerilerini olumlu yönde geliştirmiştir.
A Comparison of Native and Syrian Immigrant Women Students' Genital Hygiene Behaviors: A Cross-Sectional Study
(Univ Sao Paolo, 2025) Icke, Sibel; Cifci, Sema
Objective: This study aims to compare the genital hygiene behaviors of native and Syrian immigrant women students. Method: This was cross-sectional research. The sample size of the study was determined via power analysis and G*Power software. A total sample size of 330 individuals was equally distributed to both groups. Sociodemographic Characteristics Questionnaire" and the 'Genital Hygiene Behaviors Scale' were used as data collection tools. Results: There was a significant difference between the mean scores of the scales of both student groups (p < 0.05). The mean scores of native students were found to be higher. The variables "how to clean the genital area", "material used for genital hygiene", "washing method of underwear", "pretoilet hand washing habits" and "regular menstruation" were found to be most effective in terms of the mean scores of the Genital Hygiene Behaviors Scale and its subscales for immigrant students. Conclusion: Social security status and nationality were the most influential sociodemographic factors affecting genital hygiene behaviors. It would be beneficial to raise awareness and promote behavioral changes regarding genital hygiene through seminars, conferences, workshops, and similar events targeting all women university students.
Citation - Scopus: 3
A Rare Cause of Dysphagia: A Giant Ganglioneuroma in Parapharyngeal Space
(Springer, 2022) Aslan, Mehmet; Dogukan, Fatih Mert
Parafarengeal ganglioneuroma is a very rare benign tumor originating from the sympathetic nervous system that produces mass and functional effects. Ganglioneuroma is most commonly caused by the posterior mediastinal, retroperitoneal area and adrenal glands. Generally, they do not present any additional signs or symptoms other than mass. Horner’s syndrome may sometimes occur due to the compression of the sympathetic chain. A 41-year-old male patient with a long-standing mass in the lateral compartment of the left neck was admitted to our clinic. The patient was operated, and the pathological result of the mass was reported as ganglioneuroma. We present a rare case of ganglioneuroma in paraphryngeal space by reviewing the current literature. © 2022 Elsevier B.V., All rights reserved.
Citation - Scopus: 4
A Rare Cause of Dysphagia: Giant Lipoma in Parapharyngeal Space
(Lippincott Williams and Wilkins, 2020) Aslan, Mehmet; Ozer Ozturk, Ebru; Dogukan, Fatih Mert
Background: Parapharyngeal area is one of the most complex areas of head and neck anatomy. Tumors of the parapharyngeal region are very rare among head and neck tumors. Lipomas also constitute a tiny proportion of parapharyngeal tumors so parapharyngeal area lipomas are very rare in the literature. Due to anatomical location, these tumors treatment is challenging. Clinical Report: A 20-year-old male patient admitted to our department with complaints of swallowing difficulty and a mass on the right side of the neck. Magnetic resonance imaging was performed, and it was reported as a 6 4.5 cm lipoma. He underwent excision of parapharyngeal area lipoma by a transoral approach. Conclusion: Parapharyngeal lipomas are very rare, and difficult to diagnose before they turn out symptomatic. The primary treatment approach in tumors of the parapharyngeal area is surgery and the surgical approach should be chosen according to the anatomical location of the lesion. © 2021 Elsevier B.V., All rights reserved.
Ability of Cha2ds2-vasc/R2cha2ds2-vasc Scores To Predict Complications Related To Cardiac Implantable Electronic Devices
(Wiley, 2025) Aktan, Adem; Kilic, Raif; Guzel, Hamdullah; Tastan, Ercan; Oksul, Metin; Guzel, Tuncay; Soner, Serdar
BackgroundGlobally, the number of cardiac implantable electronic devices (CIEDs) is increasing. In our study, we aimed to investigate whether CHA(2)DS(2)-VASc and R(2)CHA(2)DS(2)-VASc scores are predictive of CIED-related complications. MethodsOur investigation was carried out with a multicenter retrospective design. Patients who underwent CIED surgery at two cardiac centers in Turkey between January 2011 and May 2023, 1676, were evaluated. The patients were divided into two groups according to their R(2)CHA(2)DS(2)-VASc scores. Patients with R(2)CHA(2)DS(2)-VASc >= 5 were included in group 1 (380 patients), and patients with R(2)CHA(2)DS(2)-VASc < 5 (1296 patients) were included in group 2. The primary outcome was defined as the cumulative events. Each component of cumulative events, such as hematoma, pericardial effusion, pneumothorax, and infection, was also defined as a secondary outcome. ResultsThe study's patient population had an average age of 62.9 +/- 14 years. Pneumothorax (1.8% vs. 1.3%, p = 0.444), pericardial effusion or tamponade (0.35% vs. 0.2%, p = 0.659), and clinically significant hematoma (1.1% vs. 0.6%, p = 0.376) were comparable between the groups. Infection-related devices and cumulative events classified as primary outcomes were higher in the R(2)CHA(2)DS(2)-VASc >= 5 group (6.1% vs. 1.2%, p < 0.001; 7.6% vs. 3.2%, p < 0.001, respectively). Modeling analyses showed that the CHA(2)DS(2)-VASc score and HT were also independent predictors of device-related infection and cumulative events. ConclusionIn the R(2)CHA(2)DS(2)-VASc >= 5 groups, infection related to the device system and cumulative events were higher. Patients with an R(2)CHA(2)DS(2)-VASc score of 5 or more and a high CHA(2)DS(2)-VASc score should be evaluated more carefully regarding infection and cumulative events before and after the operation.
Citation - WoS: 11
Citation - Scopus: 20
Activity of Metalaxyl-M plus mancozeb, Fosetyl-Al, and Phosphorous Acid against Phytophthora Crown and Root Rot of Apricot and Cherry Caused by Phytophthora palmivora
(CZECH ACADEMY AGRICULTURAL SCIENCES, 2017) Türkölmez, Şahimerdan; Derviş, Sibel; 16.01. Department of Organic Agriculture / Organik Tarım Bölümü; 16. School of Vocational Higher School of Kızıltepe/ Kızıltepe Meslek Yüksekokulu; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Crown and root rot, caused by the Oomycete pathogen Phytophthora palmivora, has become a destructive disease of apricot and cherry in eastern Turkey. There are no currently registered fungicides labeled for its control. In greenhouse experiments conducted in 2012 and 2013, 1-year-old potted apricot rootstock Zerdali and cherry rootstock Mahaleb plants were treated either with foliar spray of fosetyl-Al (140, 160, and 180 g a.i./100 l) or phosphorous acid (187.5, 200, and 215 g a.i./100 l) or soil drench of 100 ml of metalaxyl-M (= mefenoxam)+mancozeb (12+192, 16+256, and 20+320 g a.i./100 l) one day after wound inoculation of crowns and roots. In both years, phosphorous acid at 200 and 215 g a.i./100 l, fosetyl-Al at 160 and 180 g a.i./100 l, and metalaxyl-M+mancozeb at 20+320 g a.i./100 l significantly reduced the root rot severity on Zerdali by 70.68-80.00% and crown rot severity on both Zerdali and Mahaleb, by 68.32-91.96 and 74.21-82.60%, respectively, compared with phosphorous acid at 187.5 g a.i./100 l, fosetyl-Al at 140 g a.i./100 l, metalaxyl-M+mancozeb at 12+192 and 16+256 g a.i./100 l and control. Moreover, fosetyl-Al at 180 g a.i./100 l and metalaxyl-M+mancozeb at 20+320 g a.i./100 l significantly reduced the root rot severity on Mahaleb compared to fosetyl-Al at 140 and 160 g a.i./100 l, metalaxyl-M+mancozeb at 12+192 and 16+256 g a.i./100 l, phosphorous acid treatments and control in 2012, providing the best control of the disease by 88.00-90.68%. Two/three phosphorous acid foliar applications at 200 g a.i./100 l suppressed symptom development when field applications were made on a curative basis in 2014 and 2015.
Acute Cyanide Intoxication Due To Apricot Seed Ingestion
(Soc Argentina Pediatria, 2024) Talay, Mehmet N.; Gungor, Emre; Orhan, Ozhan; Department of Internal Medical Sciences / Dahili Tıp Bilimleri Bölümü; 10. Faculty of Medicine / Tıp Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Introduction : Cyanide poisoning, whether it be accidental or intentional, remains a significant danger to adults and children, especially in societies where agriculture is a primary source of income. We examined the clinical follow-up, complications, and results of cyanide poisoning cases that occurred after eating the pits and seeds of plants containing cyanide glycosides, such as apricot kernels and almonds. Methods : Between 01/01/2017 and 01/08/2022, 14 children aged 1-18 years who were followed up with a prediagnosis of cyanide poisoning in our Paediatric Intensive Care Unit (PICU) were retrospectively analysed. Results : Eight of the patients followed with a preliminary diagnosis of cyanide poisoning were female and six were male. The most common admission month was July (42.8%) coinciding with the agricultural season. The most common symptoms at presentation were weakness and fatigue (n = 7). In the PICU, 4 patients presented lip cyanosis; 3, altered level of consciousness. Vomiting, seizure, headache, dizziness and palpitatons were less frequent. Four patients were treated with hydroxocobalamin (Cyanokit (R) ) as an antidote due to acidosis in their blood gases. All patients treated for cyanide poisoning were discharged. Conclusions : Cyanide poisoning should be considered in paediatric patients with suspicious findings, sudden loss of consciousness, increased anion gap acidosis and lactic acidosis. The history of eating the seeds of plants such as apricot and almonds should be investigated .
Acute Cyanide Poisoning Due To Ingestion of Apricot Seeds
(Soc Argentina Pediatria, 2024) Talay, Mehmet N.; Gungor, Emre; Orhan, Ozhan; Department of Internal Medical Sciences / Dahili Tıp Bilimleri Bölümü; 10. Faculty of Medicine / Tıp Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
[No Abstract Available]
Citation - WoS: 18
Citation - Scopus: 19
The Adsorption and Inhibition Efficiency of 2-Amino for Corrosion of Mild Steel in Hydrochloric Acid Solution
(Emerald Group Publishing Ltd, 2023) Okten, Veysi; Yildiz, Resit; Sigircik, Goekmen; 09.03. Department of Nutrition and Dietetics/ Beslenme ve Diyetetik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
PurposeThis study aims to prevent mild steel (MS) against corrosion in 0.5 M HCl solution, 2-amino-4-methoxy-6-methyl-1,3,5-triazine was used. The effectiveness of the compound as a corrosion inhibitor was studied via electrochemical, surface and theoretical calculation techniques. Design/methodology/approachFor concentrations ranging from 0.5 to 10.0 mM, almost similar polarization resistances were obtained from electrochemical impedance spectroscopy (EIS) and linear polarization resistance tests. It also investigated inhibitive activity of 2-amino-4-methoxy-6-methyl-1,3,5-triazine on the steel surface using scanning electron and atomic force microscope instruments. Langmuir adsorption is the best matched isotherm for the adsorption of the inhibitor to the steel surface. FindingsEIS method was used to determine inhibition efficiency, which was determined to be 95.7% for 10.0 mM inhibitor containing acid solution. Density functional theory's predictions for quantum chemistry agreed well with the other experimental results. Originality/valueThe methods used in this study are effective and applicable; the used organic inhibitor is 2-amino-4-methoxy-6-methyl-1,3,5-triazine; and protective effectiveness is important, which is crucial for the task of MS corrosion prevention.
Citation - WoS: 5
Citation - Scopus: 6
Air Quality Forecasting Using Machine Learning: Comparative Analysis and Ensemble Strategies for Enhanced Prediction
(Springer Int Publ Ag, 2025) Ozupak, Yildirim; Alpsalaz, Feyyaz; Aslan, Emrah; 08.01. Department of Computer Engineering / Bilgisayar Mühendisliği Bölümü; 08. Faculty of Engineering and Architecture / Mühendislik Mimarlık Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Air pollution poses a critical challenge to environmental sustainability, public health, and urban planning. Accurate air quality prediction is essential for devising effective management strategies and early warning systems. This study utilized a dataset comprising hourly measurements of pollutants such as PM2.5, NOx, CO, and benzene, sourced from five metal oxide sensors and a certified analyzer in a polluted urban area, totaling 9,357 records collected over one year (March 2004-February 2005) from the Kaggle Air Quality Data Set. A comprehensive comparison of ten machine learning regression models XGBoost, LightGBM, Random Forest, Gradient Boosting, CatBoost, Support Vector Regression (SVR) with Bayesian Optimization, Decision Tree, K-Nearest Neighbors (KNN), Elastic Net, and Bayesian Ridge was conducted. Model performance was enhanced through Bayesian optimization and randomized cross-validation, with stacking employed to leverage the strengths of base models. Experimental results showed that hyperparameter optimization and ensemble strategies significantly improved accuracy, with the SVR model optimized via Bayesian optimization achieving the highest performance: an R2 score of 99.94%, MAE of 0.0120, and MSE of 0.0005. These findings underscore the methodology's efficacy in precisely capturing the spatial and temporal dynamics of air pollution.
Ameliorative Effects of Agomelatine Against Doxorubicin-Induced Hepatotoxicity
(BMC, 2025) Savas, Hasan Basri; Sozen, Mehmet Enes; Cuce, Gokhan; Batur, Tuba
Drug-induced hepatotoxicity is a significant impediment to the use of doxorubicin, a commonly employed chemotherapeutic agent with established efficacy in cancer treatment. The present study aimed to determine the potential protective effects of agomelatine against doxorubicin hepatotoxicity in rat toxicity models. Thirty-two rats were divided into four groups: control (with saline administration), Doxo (with 40 mg/kg doxorubicin administration), Doxo + Ago20, and Doxo + Ago40 (with 20 and 40 mg/kg agomelatine administration and 40 mg/kg doxorubicin administration). On the day of 14 rats were sacrificed, samples were collected for comparison of immunohistochemical, hematological, and biochemical analysis. There were statistically significant differences between the study groups in terms of immunohistochemical, hematological, and biochemical parameters. Agomelatine administration reduced the TNF-alpha, and caspase-3, which increased by doxorubicin, and reversed levels of oxidative stress markers altered by doxorubicin (p < 0.05). Doxorubicin induces oxidative stress, apoptosis, and hepatotoxicity. Agomelatine may be favored as a primary antidepressant to mitigate hepatic damage induced by doxorubicin.
Citation - WoS: 1
Citation - Scopus: 1
The Ameliorative Effects of Hesperidin in Rats Developed Hepatotoxicity With Deltamethrin
(Mashhad Univ Med Sciences, 2025) Karabekir, Seda Cetinkaya; Sozen, Mehmet Enes; Ayan, Ilknur Cinar; Savas, Hasan Basri; Cuce, Gokhan; Kalkan, Serpil; Department of Basic Medical Sciences / Temel Tıp Bilimleri Bölümü; 10. Faculty of Medicine / Tıp Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Objective(s): Deltamethrin (DLM) is a widely used insecticide in agriculture; however, exposure to it can lead to serious health problems. This study aimed to evaluate the protective effects of hesperidin (HSP), a natural antioxidant, against DLM-induced liver toxicity. Materials and Methods: Thirty-two male Wistar Albino rats (250-300 g, 4 months old) were divided into four groups. The control group received 1 ml of corn oil via oral gavage for 30 days. The DLM group received 1.28 mg/kg DLM in corn oil for 30 days. The DLM+HSP 100 mg/kg and DLM+HSP 300 mg/kg groups received 1.28 mg/kg DLM followed by 100 mg/kg or 300 mg/kg HSP in distilled water, respectively, 30 min after DLM administration for 30 days. Liver tissues were examined histopathologically. Masson's trichrome staining and PCR assessed fibrosis. Caspase 3 and 9 expressions in liver tissues were determined by immunohistochemistry and PCR. Biochemical analyses were conducted on serum samples. Results: HSP supplementation led to a dose-dependent decrease in aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels. DLM exposure decreased antioxidant capacity, while HSP supplementation increased it dose-dependently. Histopathological evaluations showed increased liver damage in the DLM group, while HSP administration reduced liver toxicity. Masson's trichrome staining and analysis of collagen I (COL1A1) and collagen III (COL3A1) gene expression revealed increased fibrosis in the DLM group, which was attenuated with HSP treatment. Conclusion: The potential prevention of DLM-induced liver toxicity and apoptosis by HSP may be an alternative protective strategy.
Analysis of Bioactive Compounds Using Lc-esi-ms/Ms, Cytotoxic, Antimicrobial Effects, and Enzyme Activities From Cyclotrichium Origanifolium (Vol 101, Pg 740, 2023)
(Wiley, 2024) Aktepe, N.; Baran, A.; Atalar, M. N.; Baran, F.; Keskin, C.; Taskin, A.; Jahan, I; 21.02. Department of Medical Services and Techniques / Tıbbi Hizmetler ve Teknikleri Bölümü; 09.01. Department of Nursing / Hemşirelik Bölümü; 9. Faculty of Health Sciences / Sağlık Bilimleri Fakültesi; 21. Vocational School of Health Services / Sağlık Hizmetleri Meslek Yüksekokulu; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Citation - WoS: 23
Citation - Scopus: 30
Analysis of Promising Barley (Hordeum Vulgare L.) Lines Performance by AMMI and GGE Biplot in Multiple Traits and Environment
(Aloki Applied Ecological Research and Forensic Inst Ltd, 2019) Tekdal, S.; Dogan, S.; Kendal, E.; Karaman, M.
The development of stable and adaptable new cultivars are based only on positive results obtained from the interaction between the genotype and the environment. Therefore, the study aimed to test the stability and general adaptability of promising barley lines in terms of grain yield and traits in multi -environments. For this purpose, twelve barley genotypes were used in the study. The trials were carried out with four replications in a random design at seven environments in years 2012-13 and 2013-14. The superior and stable genotypes were identified with GGE biplot and AMMI (Additive main effects and multiplicative interaction) models. The AMMI analysis showed that the major treatment sum of squares was affected by environments (80.6%), GE (14.0%) and genotypes (5.4%), respectively. On the other hand, the first two principal component axes (PCA 1 and PCA 2) contributed to the complete interaction with 88.1%, whereas, PCA 3 and PCA 4 axes only with 12.0%. The GGE biplot indicated that G4 is adaptable for all environments, while Altikat, G2 and G3 showed specific adaptation to El, E3 and E5, G6, G7 and G8 to E6, respectively. According to both techniques, G2, G3, G6, G7, G8 and Altikat were the best genotypes with high yield, whereas G4 was the best with high yield, and stable and general adaptation. The results of biplot indicated that G4 (ARUPO /K8755//MORA/3/CERISE/SHYRIHALEL I/4/CANELA/5/HART-BAR) was recommended for release and it was released as HEVSEL in 2017. On the other hand; G7 and G6 were protected as genetic material to use as parent in breeding programs for yield stability and quality respectively.
Analysis of Pyrolysis Liquid From Green Walnut Shells (Juglans Regia L.) and Its Antifungal Activity Against Pathogenic Fungi in Ornamental Plants
(Aloki Applied Ecological Research and Forensic Inst Ltd, 2025) Koc, I
Pathogenic fungi damage ornamental plant production in both quality and quantity. Organic fungicides are significantly needed for the control of these pathogens. This study was carried out to analyze the content of pyrolysis liquid (PL) obtained from green walnut shells (Juglans regia L.) and to evaluate its antifungal activity against Fusarium oxysporum and Verticillium dahliae. This research was carried out under in vitro conditions with 5%, 10%, 15%, 20% and 25% (v/v) PL solution applications in a Randomized Plot Design with four replications. The Poisoned Food Method was used to determine the antifungal activity of PL. As a result of chemical content analysis of PL, 53 components were detected by GC-MC, and the major components were propanoic acid, 2-hydroxy-(CAS) (21.69%), e-2-undecenal (7.11%), and nonanal (5.76%). Twelve components were detected by LC-MS/MS, with vanillic acid (393.28 mu g/L), vanillin (334.34 mu g/L), and syringic acid (222.80 mu g/L) identified as the major components. Total phenolic content (201.76 +/- 12.50 mg GAE/mL) and total flavonoid content (114.74 +/- 4.50 mg QE/mL) were determined. Therefore, the effect of concentration on colony size varied depending on the species. It was determined that PL showed stronger antifungal activity at higher concentrations, with the highest activity observed at the 25% (v/v) solution.
Citation - WoS: 1
Citation - Scopus: 1
Anatolian Medicinal Plants as Potential Antiviral Agents: Bridging Traditional Knowledge and Modern Science in the Fight Against Covid-19 and Related Viral Infections
(Tubitak Scientific & Technological Research Council Turkey, 2024) Tilkat, Engin; Jahan, Israt; Hoser, Ayse; Kaplan, Alevcan; Ozdemir, Oguzhan; Onay, Ahmet; 21.01. Department of Health and Nursing Services / Sağlık ve Bakım Hizmetleri Bölümü; 21. Vocational School of Health Services / Sağlık Hizmetleri Meslek Yüksekokulu; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was the cause of the coronavirus 2019 (COVID-19), commonly known as the coronavirus pandemic. Since December 2020, COVID-19 vaccines have been extensively administered in numerous countries. In addition to new antiviral medications, the treatment regimen encompasses symptom management. Despite sustained research efforts, the outbreak remains uncontrolled, with affected patients still lacking proper treatment. This review is a valuable asset for researchers and practitioners aiming to delve into the yet unexplored potential of Anatolian flora in the fight against COVID-19 and other viral infections. Numerous medicinal plants in Anatolia, such as thyme, sage, cannabis, oregano, licorice root, and Origanum sp., contain bioactive compounds with proven antiviral properties that have been used in the region for centuries. The rich legacy of traditional Anatolian medicine (TAM), has significantly influenced modern medicine; thus, the profusion of medicinal plants native to Anatolia holds promise for antiviral drug development, making this review essential for researchers and practitioners.
An Animal Model of Reperfusion in Ischemic Corporal Tissue and the Effect of Sugammadex on Oxidative Injury Parameters
(MRE Press, 2025) Kolukcu, Vildan; Yalcin, Kenan; Eroglu, Askin; Gevrek, Fikret; Gurpinar, Ahmet Burak; Unsal, Velid
Background: The aim of this study was to analyze the effect of sugammadex on ischemia-reperfusion injury in corporal tissue. Methods: Eighteen male Wistar Albino strain rats were divided into three groups. Group 1 served as the control group. A priapism model was induced in rats in Group 2 and 3. Rats in Group 3 were additionally administered 4 mg/kg sugammadex intravenously immediately after reperfusion. All rats underwent penectomy for histopathological and biochemical evaluations, and blood samples were collected. Results: In Group 2, total oxidant status (TOS) and malondialdehyde (MDA) levels were significantly higher compared to other groups (p < 0.001 and p = 0.009, respectively). A substantial reduction in both TOS and MDA levels was found in Group 3 (p <0.001 and p = 0.043, respectively). Group 2 exhibited significantly lower activities of a glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) compared to Group 1 (p = 0.043 and p = 0.024, respectively). In contrast, Group 3 showed significant increases in both antioxidant enzyme activities (p = 0.036 and p = 0.034, respectively). Similarly, the total antioxidant status (TAS) was dramatically higher in Group 3 compared to Group 2 (p < 0.001). Microscopic examinations revealed improvements in vasocongestion, edema, desquamation and inflammation scores in Group 3 compared to Group 2 (p < 0.001). Conclusions: Biochemical and histopathological findings suggest that, sugammadex significantly mitigates oxidative damage parameters in corporal tissue affected by ischemia-reperfusion injury.
Citation - WoS: 4
Citation - Scopus: 4
Animal Remains of Alaybeyi Hoyuk
(Tubitak Scientific & Technological Research Council Turkey, 2019) Siddiq, Abu Bakar; 02.01. Department of Anthropology / Antropoloji Bölümü; 02. Faculty of Letters / Edebiyat Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
This paper presents the zooarchaeological observations on animal remains of Alaybeyi Hoyuk unearthed from 2016 and 2017 excavation sessions. Dated to 4721-4553 cal. BC, Alaybeyi stands so far as the oldest archaeological settlement discovered in northeast Anatolia. Therefore, the faunal assemblage at Alaybeyi offers great opportunity to study the status of animals and their relationships with humans in the largely unexplored Kars-Erzurum plateau covering a period from the Chalcolithic to Late Iron Age. Taxonomic and osteometric analyses show that, like the present day, cattle were dominant over caprines, revealing extensive cattle pastoralism in the region for at least about 7 millennia. While caprines too were significant in the subsistence strategy of local humans, there was not any sign of raising pigs. Significant numbers of wild species including carnivores, aquatic mammals, and rodents, as well as resident and migratory birds, were also hunted by Alaybeyi people. Additionally, horse burials, horse cult, dog burials, and a rich number of dog bones present animals as versatile actors in various ritual and symbolic practices at the site.
Citation - Scopus: 1
Ankara huseyin gazi tomb in the context of mountain, water, and cave cults;
(Gazi Universitesi, Turk Kulturu ve Haci Bektas Veli, 2017) Akyüz, Ç.; 02.15. Department of Turkish language and Literature / Türk Dili ve Edebiyatı Bölümü; 02. Faculty of Letters / Edebiyat Fakültesi; 01. Mardin Artuklu University / Mardin Artuklu Üniversitesi
Mountain is believed to keep the earth "stand straight" and conceived as a space of God to carve out the highest point of the earth. They shape traditional practices and social life as a cult in the old Turkish belief system. It contains rushing rivers, the springs and the sources of rivers. Water is the source of the material and spiritual life and it is considered to be sacred. In this regard, it can be said that many sacred narrative formed around the mountains and the water. Mountain and cave are also contemplation places for divine personality. Huseyin Gazi, one of the saints in Anatolia, who is believed to live in Mamak, Ankara, there is a mountain and a tomb by his name and stories associated with his sacred personality. Water metaphor is also noteworthy in a dialectical interaction with both mountain and Huseyin Gazi is blessed in this stories. In this regard, such stories refer naming the places in the context of the sacred mountain and cave metaphores and providing information about the origin of water resources in the context of the metaphor of holy water. In this study, stories that talk about Huseyin Gazi are handled in the context of mountain, water, and cave cults by analyzing printed materials and interviewing people. The issues of evolvement of historical personalities into phenomenon and mythical place names are also studied.Within this faremework in the foregoing verbal data about Huseyin Gazi indicates that his holy personality passes ahead of his historical personality.

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