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Article Müzakere, Hız, Politika: Uluslararası Arabuluculukta Digital Teknolojilerin Kullanımı(Istanbul Univ, 2023) Burc, Safiye AtesThe super -accelerated (high-speed) life experiences and coercive practices of the new world order (Covid and post-Covid periods) have affected and changed the negotiation and conflict resolution skills of international actors. Today, with the pandemic and technological developments, acceleration has become a necessity in many fields. Many international mediators, especially the United Nations (UN), have also benefited greatly from digital technologies that pierce space and time during the most severe times of the Covid-19 pandemic. So, in today's world, where economic, social and technological development continues at high speed, should negotiations and policies keep pace? If so, how should accelerated and virtualised political practices be discussed over conflict resolution? What is the impact of digitalisation on international mediation? This article critically discusses the relationship between digitalisation, speed, politics and conflict resolution through content and discourse analysis of political reports on peacemaking practices of different UN missions, especially during the most traumatic period of the pandemic (March 2020 -March 2021). The study concludes that politics and negotiations need speed barriers because they need time, but they cannot be isolated from the developments and space of the high-speed society, so they need to follow the virtual space at all times and get involved when needed. As the analyses of the missions' reports show, the effective use of digital technologies, especially during the pandemic, has led to a rapid transformation in mediation (from traditional to cyber-mediation) and conflict resolution activities have been able to continue uninterrupted, but the dangers of digitalisation have not disappearedArticle Relationship Between Lymph Node Metastasis and Lymph Node Density and Preoperative Neutrophil-Lymphocyte Ratio in Patients Undergoing Radical Cystectomy(UROONKOLOJI BULTENI-BULLETIN OF UROONCOLOGY, 2021) Kölükçü, Engin; Atılgan, Doğan; Kuyucu, Yunus Emre; Unsal, Velid; Özbek, Latif MustafaObjective: This study aimed to evaluate the relationship between the preoperative neutrophil-lymphocyte ratio (NLR) and lymph node metastasis and lymph node density after radical cystectomy in patients with invasive urinary bladder cancer. Materials and Methods: Data of 89 patients who underwent radical cystectomy were examined. Our study included only cases with stage 2 urothelial bladder cancer. They were classified according to the lymph node status based on the surgical specimen. Patients with negative results were classified as group 1 and those with positive results as group 2. Patients in group 2 were further evaluated in two subgroups according to their lymph node density. Accordingly, group 2A consisted of patients with lymph node density of <20%, and group 2B involved those with lymph node density of ≥20%. Groups were compared statistically according to NLR. Results: Of the patients, 71 (79.8%) were male. The patients’ mean ages and neutrophil and lymphocyte counts were 67.36±8.64 years, 6.89±3.02 K/µL, and 3.08±2.18 K/µL, respectively. NLRs of groups 1 and 2 were 2.80±2.25 and 4.59±2.97, respectively. The relationship between group 1 and 2 tumors was significant (p=0.008). NLR values were 3.82±2.49 and 5.20±3.25 in groups 2A and 2B, respectively. However, no significant relationship was found between these values (p=0.235). Conclusion: Although no positive correlation was found between NLR and lymph node density, we think that this inflammation marker is an invaluable parameter to predict lymph node metastasisArticle Citation - WoS: 1Citation - Scopus: 1Oxidative Stress Enzyme NOX1 Is a New and Important Biomarker for Childhood Appendicitis?(SpringerLink, 2023) Avcı, Veli; Ayengin, Kemal; Huyut, Zubeyir; Huyut, Mehmet Tahir; Soysal, Lokman; Bilici, SalimDelayed appendicitis diagnosis may result in perforation and an increased risk of mortality. This study aimed to assess the diagnostic value of ischemia-modifed albumin, nicotinamide adenine dinucleotide phosphate oxidase 1, 2, and 4 levels in the diagnosis of non-complicated and complicated appendicitis. The study included 60 pediatric patients who presented to our clinic with a complaint of abdominal pain and underwent surgery with a diagnosis of appendicitis between November 2020 and December 2021 and also included 30 controls. Cases were divided into three groups: (i) non-complicated appendicitis (n = 30), (ii) complicated appendicitis (n = 30), and (iii) control (n = 30). The nicotinamide adenine dinucleotide phosphate oxidase 1 and 4 and ischemia-modifed albumin levels were higher in non-complicated and complicated appendicitis compared to the control (p < 0.001). In addition, considering the odds ratio values, the most efective biomarkers in the diagnosis were nicotinamide adenine dinucleotide phosphate oxidase 1 and 2, and procalcitonin, while the most efective biomarkers in the prognosis were nicotinamide adenine dinucleotide phosphate oxidase 1 and 2, and neotrophil/lymphocyte ratios. The data suggested that since the most successful biomarker nicotinamide adenine dinucleotide phosphate oxidase 1, with a value of 0.98- area under the curve, is the most successful biomarker in both diagnosis and prognosis of the disease, it can be used as an important biomarker in childhood appendicitis.Article Could the Umbilical Cord Suggest the Method of Anesthesia?(Galenos Publishing House, 2023)Objective: We aimed to investigate changes in aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), creatine kinase-myocardial band (CK-MB), and troponin I levels, which were biochemical parameters that gave an idea regarding clinical conditions such as tissue damage and asphyxia, according to the anesthesia type, to compare their levels in mothers who gave birth with normal spontaneous vaginal delivery (NSVD) and to investigate whether the type of anesthesia applied caused a change in biochemical parameters. Methods: Of the 90 patients included in the present study, 30 (33.3%) underwent general anesthesia, while 30 (33.3%) underwent spinal anesthesia, and 30 (33.3%) gave birth with NSVD. AST, ALT, LDH, CK-MB, and troponin I levels were measured in all pregnant women before they were taken to the operating room or delivery room. After the baby was delivered, a blood sample was taken from the umblical artery to measure AST, ALT, LDH, CKMB, and troponin I levels. The APGAR scores, the need for oxygen, positive pressure ventilation, and intubation after delivery of the newborns were recorded. Results: Statistically significant increases were found in AST, ALT, LDH, and troponin I levels in umblical artery in all groups when compared with their levels in pregnant women before delivery. Conclusion: An increase in umbilical artery CK-MB and ALT levels was observed in the NSVD group. Due to the increase in umbilical artery CK-MB and ALT levels in the NSVD group, it was found that it was not appropriate to evaluate the effects of anesthesia on the newborn with these markersArticle Citation - WoS: 1Citation - Scopus: 1Isocarpine as A New Peperidine Alkaloid from Adenocarpus Complicatus with Anticandidal Activity(Ingenta Connect, 2022) Alhilal, Mohammad; Alhilal, Suzan; Gomha, SobhiBackground: Adenocarpus complicatus L. is one of Adenocarpus genus, which has about 50 species, from Fabaceae (Papilionaceae) family. This plant is found in the Mediterranean basin as a southern west part of Europe and North Afric forestes. Objective: Isolation of Isocarpine From Adenocarpus Complicatus as Anticandidal Agent. Methods: A new piperidine alkaloid Isocarpine was isolated from the aerial parts of Adenocarpus complicatus L., which is gross in Syria. The structure of the new compound was determined by UV, IR, EI-Ms, 1H-NMR, 13C-NMR, DEPT-135, DQF-COSY and HMQC. Results: The anticandidal activity of isocarpine was screened against 38 Candida strains and showed remarkable inhibitory effect compared with fluconazole as an antifungal reference drug. Conclusion: Isocarpine is antifungal agent.Article Citation - WoS: 6Citation - Scopus: 3Protective effects of apocynin and melatonin on ovarian ischemia/reperfusion injury in rats(Clinical and Experimental Obstetrics and Gynecology, 2021) Unsal, Velid; İşgüder, Çiğdem Kunt; Can, Özlem Koşar; Pektaş, Mine Kanat; Arici, AkgülObjective: This study aims to determine the protective effects of apocynin, a NADPH oxidase inhibitor, and melatonin, an endogenous anti-oxidant, in an animal model of ovarian ischemia/reperfusion (I/R) injury. Materials/Methods: Thirty-five female rats were randomly divided into five groups, namely group I (sham), group II (I/R), group III (I/R + 10 mg/kg apocynin), group IV (I/R + 20 mg/kg apocynin), and group V (I/R + 10 mg/kg melatonin). Ovarian tissue and serum superoxide dismutase (SOD) and catalase (CAT) activities and malondialdehyde (MDA) and protein carbonyl (PC) levels were measured. Ovarian histopathology was examined and Bax, caspase 3, and iNOS immunoreactivities were evaluated. Results: Preoperative apocynin and melatonin significantly increased SOD and CAT activities (P < 0.05, P < 0.05, P < 0.01, P < 0.01, P < 0.01, P < 0.05, P < 0.05, and P<0.01, respectively, for both apocynin and melatonin). In addition, preoperative apocynin and melatonin significantly decreased the ovarian I/R injury score (P < 0.01 for both). Bax, caspase 3, and iNOS immunoreactivities were significantly lower in the I/R + 10 mg/kg apocynin and I/R + 10 mg/kg melatonin groups than in the I/R group (P<0.01, P<0.01, P<0.01, P<0.01, P<0.05, and P<0.01, respectively). Conclusions: Apocynin and melatonin are powerful antioxidant agents with considerable bioavailability and safety. Preoperative apocynin and melatonin administration might protect ovarian tissue from I/R injury after surgical adnexal detorsion.Article Evaluation of Nurses' and Midwives' Knowledge and Attitudes Towards Recognizing Violence Against Women(Womens Health & Action Research Centre, 2024) Donmez, Ayseguel; Yesil, YesimThe study was cross-sectional research that surveyed 410 nurses and midwives from March 2020 to March 2021 in Turkey. The aim of this study was to evaluate the knowledge and attitudes of nurses and midwives towards recognizing violence against women. The "Scale for Nurses' and Midwives' Recognition of the Symptoms of Violence against Women" were used. The average total scale score was 20.3 +/- 3.2. The score of participants who are receiving postgraduate education, working in the field of gynaecology and obstetrics, and considering intervention as a professional responsibility when encountering a woman who has experienced violence was found to be significantly higher than the other groups (p<.05). It is important for midwives and nurses to be aware of signs of violence to identify violence against women. Providing education to midwives and nurses regarding signs of violence against women will contribute to the recognition, prevention, and awareness of violence. (Afr J Reprod Health 2024; 28 [2]: 116-124)Book Review The Plain of Saints and Prophets: The Nusayri-Alawi Community of Cilicia (Southern Turkey) and its Sacred Places(Cambridge University Press, 2011) Soileau, MarkGisela Procházka-Eisl and Stephan Procházka. The Plain of Saints and Prophets: The Nusayri-Alawi Community of Cilicia (Southern Turkey) and its Sacred Places. Wiesbaden: Harrassowitz Verlag, 2010. 404 pages, 61 color pictures. Cloth €68 ISBN 978–3-447–06178-0.Article Citation - Scopus: 1The interaction methylene blue and glutathione-S-transferase purified from human erythrocytes(Journal of Planar Chromatography - Modern TLC, 2020) Acay, Hilal; Uzan, Serhat; Baran, Mehmet Fırat; Bilden, Alican; Aygün, HüsamettinIt is known that textile dyes have various risks on human health. Glutathione-S-transferase enzymes play a critical role in the detoxification of xenobiotics in living systems. This study aimed to examine the interaction of methylene blue with human erythrocyte glutathione-S-transferase purified in one step. Human erythrocyte glutathione-S-transferase was purified with approximately 750-fold purification and 30% efficiency by glutathione agarose affinity chromatography. The results showed that the enzyme was inhibited by methylene blue with an IC50 value of 1.40 mmol/L. The Ki constant of methylene blue was 1.17 mmol/L. The Lineweaver–Burk graph of the methylene blue showed that the type of inhibition was compatible with mixed type inhibition. A new third spot was also detected by thin-layer chromatography. Furthermore, the cytotoxicity of methylene blue on human erythrocytes was evaluated and it was found that the haemolysis per cent of methylene blue on erythrocytes was approximately 14%.Article Citation - WoS: 7Citation - Scopus: 5Sağlam çocuk polikliniğine başvuran 0-1 yaş bebeği olan annelerde depresyon taraması ve depresyonda etkili risk faktörlerini belirleme(2012) Battaloğlu İnanç, Betül; Aydemir, Nurcihan; Hatipoğlu, SamiSağlam çocuk polikliniğine başvuran 0-1 yaş bebeği olan annelerde Edinburgh Postnatal Depresyon Skalası (EPDS) ölçeğini kullanarak, depresyon oranlarını saptamayı ve etkili olan sosyodemografik faktörleri belirleyerek, elde edilen sonuçların diğer çalışmalarla korelasyonunu değerlendirmeyi amaçladık. Gereç ve Yöntem: 20 Temmuz- 20 Eylül 2007 tarihleri arasında, 0-1 yaş arası bebeği olan anneler çalışmaya dâhil edildi. 211 anne çalışmaya katıldı, postpartum sosyodemografik veri formu ile EPDS kullanıldı. Çalışmaya katılmayı kabul etmeyen 28 annenin, 7’sinde EPDS puanlaması depresyon için anlamlı değerlerde idi. Toplam 183 annenin verileri değerlendirmeye alındı. Annelerin sosyodemografik özelliklerini belirlemek için toplam 51 sorudan oluşan postpartum sosyodemografik veri formu kullanıldı. Depresyon yaygınlığını saptamak amacıyla annelere 10 sorudan oluşan EPDS ölçeği uygulandı. Değerlendirme 30 puan üzerinden yapıldı ve kesme puanı 13 ve üzeri ( ?13) olarak alındı. Bulgular: EPDS kesme puanı ?13 alınarak hesaplanan depresyon semptomatoloji skoru %30.6’dır. Çalışmaya katılan kadınların yaş ortalaması 27.5±5.45, yaş dağılımı 18 ile 43 arasında değişmektedir. EPDS puanı yüksek olanlarda evlilikten memnuniyet düzeyinin iyi olma oranı anlamlı düzeyde düşük; evlilikten memnuniyetleri orta ve kötü düzeyde olanlarda, psikiyatrik özgeçmişi olan annelerde ise EPDS puanları anlamlı düzeyde yüksek olarak saptanmıştır (p<0.01). Eşi çalışmayan, planlanmamış gebeliği olan, doğumda annede sağlık sorunu olan,gece doğum yapan annelerde EPDS puanlaması yüksek olarak görülmektedir (p<0.05). Bebekte sağlık sorunu olduğunu belirten, bebek bakımını güç olarak tarifleyenlerde, bebeğini emzirmeyen kadınlarda EPDS puanlaması istatistiksel olarak anlamlı düzeyde yüksek olarak saptanmıştır (p<0.01). Sonuç: Doğum sonrası depresyon birçok anneyi ve bebeği olumsuz etkileyen ciddi bir sorundur. Etkin bir tedavinin mümkün olmasına rağmen, olguların yarısından azı fark edilebilmektedir. Kitlelerin taranması, antenatal dönem, doğum sonrası erken dönem ve normal sağlam çocuk izlemleri döneminde, doğum sonrası depresyon tanısı koyabilme imkanını mümkündür. Toplumu temsil eden, büyük kitlelere yapılacak topluma dayalı çalışmalar ile geçerli, etkin bir doğum sonrası depresyon taramasının tanımlanmasına ve bu tip bir taramanın klinik olarak anne -bebek açısından hizmetin artırılmasına, olan etkisinin belirlenmesine gereksinim vardır.Article Citation - WoS: 17Citation - Scopus: 23Rapid green synthesis of gold nanoparticles: synthesis, characterization, and antimicrobial activities(Progress in Nutrition, 2021) Hatipoğlu, AbdulkerimIn this research, an easy and environmentally friendly method was presented for the biosynthesis of gold nanoparticles (AuNPs) with Allium ampeloprasum (AA) leaf extract as a reducing and stabilizing agent. The maximum absorption peak was found to be around 535 nm with ultraviolet (UV)-visible spectrophotometer. When the Transmission Electron Microscopy (TEM), Emission Scanning Electron Microscopy (FE-SEM) and energy dispersive X-ray (EDX) analyzes were examined, it was seen that the crystal size of the synthesized AuNPs was between 6.02-17.36 nm and their shape was mostly spherical. The size of the crystal structures of AuNPs was calculated as 22.76 nm from the X-ray diffraction (XRD) analysis data. Fourier Transform Infrared (FT-IR) Spectroscopy results showed that phenolics, aromatic compounds and proteins were effective in the reduction and stabilization of AA-AuNPs. The average size of AuNPs was determined as 96.46 nm with Zetasizer. It was determined that AuNPs have a very strong inhibitory effect on pathogenic bacteria (Escherichia coli, Staphylococcus aureus, Bacillus subtillis and Pseudomonas aeruginosa) and Candida albicans by the minimum inhibitory concentration (MIC) method.Article Citation - WoS: 6Mediator Role of Metacognitive Awareness in the Relationship between Educational Stress and School Burnout among Adolescents(2017) Sarıçam,Hakan; Çelik, İsmail; Halis SakızBireyin görev ve stratejiler hakkındaki bilgilere ek olarak öğrenmeyi planlama, kullanma, düzenleme ve öğrenme stratejilerini değerlendirme gibi üstbiliş becerilerinden oluşan metabiliş, öğrencilerin öğrenmelerini doğrudan etkileyen bir süreç olarak kabul edilir. Eğitim stresi öğrencilerin okulda ya da okul dışındaki başarısını etkileyen, okul ile ilgili görevleri yerine getirmek için karşılaştıkları problemlere verilen bir reaksiyondur. Okul tükenmişliği ise bir öğrenci olarak yetersiz hissetme, okula karşı soğuma ve okul gerekliliklerine karşı tükenmeye dayanan bir kavramdır. Bu çalışmanın amacı eğitim stresi, okul tükenmişliği ve üstbiliş arasındaki ilişkiyi belirlemek ve eğitim stresi ile okul tükenmişliği arasındaki ilişkide üstbilişsel farkındalığın aracı rolünü incelemektir. Çalışmanın örneklemi, Ağrı ilinde ortaokula devam eden 7. ve 8. sınıflardan seçilmiş 303 öğrenciden oluşmaktadır. Veri toplamak amacıyla "Ortaokul Üstbilişsel Farkındalık Envanteri" ile "Eğitim Stresi ve Okul Tükenmişliği Ölçeği" kullanılmıştır. Değişkenler arası ilişkileri saptamak için Pearson Momenler Çarpımı Korelasyon analizi ve okul tükenmişiği üzerinde üstbiliş ve eğitim stresinin yordama gücünü tespit etmek için basit ve Çoklu/Aşamalı Regresyon analizi kullanılmıştır. Korelasyon analizi sonucuna göre; üstbiliş, eğitim stresi ve okul tükenmişliği arasında istatistiksel olarak önemli ilişkilerin olduğu, aşamalı regresyon analizi sonucuna göre ise; üstbilişsel farkındalığın, eğitim stresi ve okul tükenmişliği arasında aracı role sahip olduğu ve eğitim stresinin okul tükenmişliğinin güçlü bir yordayıcısı olduğu tespit edilmiştirArticle Understanding new consumer trends in Turkey through coffee production and consumption in Mardin(Anthropological Notebooks, 2022) Cengiz, Alim Koray; Uygur, Hatice KübraCoffee which helps us to learn about the cultural practices of a society, is an important consumption commodity not only in Turkey but also in the world. In this study, various specialty coffees produced by coffee producers in Artuklu, the historical district of Mardin, the rapid change of cafes and the purchasing practices of consumers have been examined. Ethnographic interviews have also been conducted with coffee producers, cafe owners and consumers. Coffee producers produce various coffees such as Turkish, Assyrian, Kurdish, Dibek and cardamom reflecting the multicultural structure of the city. Cafe owners and producers use expressions and images that emulate antiquity in their brands and logos. The cafes as “third place” become flamboyant spacious spaces leaving their traditional appearance. The consumption of new products by visitors of Mardin, an important place for domestic tourists, indicates a new class that seeks pleasure and experience in Turkey.Article Mediator Role of Metacognitive Awareness in the Relationship between Educational Stress and School Burnout among Adolescents(2017) Sarıçam, Hakan; Çelik, İsmail; Sakız, HalisMetacognition is accepted as a process that affect learning of students directly and is composed of metacognitive skills such as planning of learning, use, regulation and evaluation of learning strategies as well as information on the individual, duty and strategy variables. Educational stress is defined as reactions given by all individuals in the school to the problems they encounter as they carry out their duties and it has an impact on their success both at and outside of school. School burnout is handled in the dimensions of exhaustion against school demands, scornful attitude towards school and the inadequacy felt as a student. The aim of this study is to investigate the relationship between metacognition, educational stress and school burnout and the mediator role of metacognitive awareness in the relationship between educational stress and school burnout. The sample of 303 students was selected from 7th, and 8th grade students who were at 13, 14 and 15 years old at middle schools in Ağrı, Turkey. The Junior Metacognitive Awareness Inventory, the Educational Stress Scale and the School Burnout Scale were used for data collection. Pearson Product Moment Correlation Analysis was applied in order to determine relationship between the variables and simple, multiple/stepwise regression analysis were used to determine predictor roles of metacognition and educational stress on the school burnout. In correlation analysis, there are statistical significant correlations between metacognition, educational stress and school burnout. In stepwise regression analysis, metacognition is a mediator in relationship between educational stress and school burnout, and educational stress was strongest predictor of school burnout.Article Common and atypical otorhinolaryngological findings of Covid-19(Cukurova Medical Journal, 2021) Sarı, Neslihan; Arslan, Nurgül; Bayram Değer, VasfiyePurpose: Several atypical presentations of COVID-19 like anosmia, conjuctivitis, and gastrointestinal findings are seen in the literature. The purpose of this study was to investigate the common and atypical symptoms of COVID-19 among the patients admitted to the otorhinolaryngology (ENT) outpatient clinic. Materials and Methods: This case series was conducted with 49 patients who applied to hospital between April 1, 2020 and April 30, 2020. Common and atypical otolaryngological findings were recorded. Sociodemographic findings and blood parameters were also evaluated. Results: Of the patients, 59.18% were aged 40 and over, 46.94% were of the A blood group, 55.10% were male and 24.49% were smokers, 51.02% had a chronic disease. Among typical symptoms; fever (71.43%), a dry cough (46.94%), shortness of breath (42.86%) was seen. Diarrhea (48.98%), runny nose (51.02%), nasal congestion (42.85%), sore throat (22.44%), headaches (32.65%), 18.36% olfactory disorder, 26.53% gustatory disturbance were noted. Olfactory and gustatory disturbances are found to be related to good prognosis and mild clinical course. The difference between Hg and D–dimer levels of the female and male patients were found to be statistically significant. The D-dimer levels determined in the present study were higher than those reported in the literature. Conclusion: While COVID-19 present with common symptoms, sometimes atypical symptoms can be the only finding during initial application to the hospital. Olfactory and gustatory disturbances point to the effects of COVID-19 on neurons. Neuronal effects like olfactory and gustatory disturbances should be closely monitored in COVID-19 patients in long term.Article Evaluation Of The Relationship Between Foreign Trade Liberalization And Unemployment Within The Framework Of The Heterogeneous Firm Model;(Sosyoekonomi Soc, 2022) Cirkin, Zeynep; Goksel, TurkmenThis study investigates how foreign trade liberalization affects unemployment by using the Melitz model (2003), which is one of the intra-industry trade models expressing trade between countries with similar technologies, preferences, and cost structures that make up a large part of international trade. The Melitz model (2003) is remodelled by efficiency wage theory to endogenize unemployment. The model is solved by numerical method. It is assumed that market expansion and competition in the market occur simultaneously. The effect of liberalization on unemployment varies depending on which of two factors, market expansion or competition, dominates the other. According to the results, unemployment decreases when market expansion dominates the competition, while unemployment increases if competition dominates market expansion. In addition, it has been observed that there is an increase in the total amount of production, productivity, and unemployment insurance when market expansion is dominant. Also, it has been observed that there is a decrease in the total amount of production, productivity level, and unemployment insurance when competition in the market is dominant.Article Citation - WoS: 14Citation - Scopus: 16Green synthesis of gold nanoparticles from prunus cerasifera pissardii nigra leaf and their antimicrobial activities on some food pathogens(Progress in Nutrition, 2021) Hatipoğlu, AbdulkerimIn this study, a new and easy method for the biosynthesis of gold nanoparticles (AuNPs) with Prunus cerasifera pissardii nigra (PC) leaf extract as a reducing and stabilizing agent was presented. The nanoparticles were demonstrated a characteristic peak at the maximum wavelength of 535 nm with colour change as a result of the ultraviolet (UV)-visible spectrophotometer analysis data. Emission Scanning Electron Microscopy (FE-SEM), Transmission Electron Microscopy (TEM) and energy-dispersive X-ray spectroscopy (EDX) analyzes revealed that the crystal size of the synthesized AuNPs was below 20 nm and the morphological structure was mostly spherical. The size of the crystal structures of AuNPs was calculated as 17.94 nm from the X-ray diffraction (XRD) analysis data. Fourier Transform Infrared (FT-IR) Spectroscopy results confirmed the involvement of various biomolecules in the reduction and stabilization of PC-AuNPs. The zeta potential of the synthesized nanomaterial was measured as -27 mV. The average size of AuNPs was determined as 103.8 nm with Zetasizer. It was determined that AuNPs have strong inhibitory activity against Escherichia coli, Staphylococcus aureus, Bacillus subtillis and Pseudomonas aeruginosa and Candida albicans.Article Citation - WoS: 6Citation - Scopus: 6Cranial size and shape sexual dimorphism in the Kangal dog from Turkey(Scientific and Technological Research Council of Turkey (TÜBİTAK), 2020) Pars-Casanova, Pere M.; Sıddıq, Abu Bakar; Onar, VedatThis study has so far been the first attempt to characterize and quantify skull sexual variation in Kangal dog, by means of geometric morphometric techniques. A sample of 16 adult Kangal crania has been analyzed with this purpose. To obtain a full image of morphological pattern, digital pictures were taken from the ventral, left lateral, and dorsal sides of each skull, and a total of 16, 15, and 16 landmarks respectively were obtained on each image. Skull size and shape differed significantly in all aspects among different sexes, male skulls being bigger. Shape differences were observed mainly on zygomatic arch and muzzle on the dorsal view, pterygoid bone and articular surface to mandibular condyle in the lateral aspect, and cranial width and maxillary bone on the ventral view. Although the sample was comparatively small in number, being the first geometric morphometric approach applied on the Kangal dog, the obtained results will add vital information particularly to understand the cranial shape sexual dimorphism of this unique dog breed in Turkey.Article Türkiye’de Çevresel Kuznets Eğrisi Hipotezinin Ekonomik Büyüme ve Farklı Küreselleşme Türleri Bakımından Analizi(2023) Atay Polat, Melike; Ergün, SuzanÇevre kirliliği günümüzde araştırmacılar, bilim adamları ve politika yapıcılar tarafından geniş çapta üzerinde en fazla durulan konulardan biri haline gelmiştir. Özellikle CO2 salınımının belirleyicilerini araştırmak bilim adamları için önde gelen ilgi alanlarından biridir. Diğer yandan küreselleşme, ülkelerin ekonomik, politik ve sosyal yönlerden birbirleriyle etkileşime geçmesine neden olur ve kaçınılmaz olarak bu etkileşimden çevre etkilenir. Bu nedenle küreselleşme CO2 emisyonlarının önemli bir belirleyicisidir. Bu çalışma, 1970-2018 döneminde Türkiye’de Çevresel Kuznets Eğrisi hipotezinden hareketle farklı küreselleşme türlerinin (ekonomik, sosyal ve politik) çevre kalitesi üzerindeki dinamik etkilerini Vektör Hata Düzeltme Modeli (VECM) ile değerlendirmeyi amaçlamıştır. Türkiye için kişi başı CO2 emisyonu, kişi başı GSYH, ekonomik küreselleşme, sosyal küreselleşme ve politik küreselleşme arasında uzun dönem ilişkinin varlığı Johansen eşbütünleşme testi ile ortaya konmuştur. VECM Granger nedensellik testi sonuçlarına göre kısa dönemde ekonomik küreselleşmeden CO2 emisyonuna ve sosyal küreselleşmeden politik küreselleşmeye doğru tek yönlü nedensellik ilişkisi tespit edilmiştir. Ayrıca, uzun dönem tahmincileri bakımından kişi başı GSYH, ekonomik ve sosyal küreselleşmenin kişi başı CO2 emisyonunu pozitif yönde etkilediği, buna karşılık kişi başı GSYH’nın karesi ve politik küreselleşmenin kişi başı CO2 emisyonunu negatif yönde ve anlamlı olarak etkilediği sonucuna ulaşılmıştır. Bulgular, Türkiye’de politika yapıcıların çevresel kaliteyi iyileştirmesi için iklim değişikliği politikalarını belirlerken ve uygularken farklı küreselleşme türlerini de dikkate almaları gerektiğini göstermektediArticle Citation - WoS: 1Citation - Scopus: 1Effectiveness of Valproic Acid in the Treatment of Sydenham's Chorea and a Literature Review(Sage Publications inc, 2024) Ozgun, Nezir; Akdeniz, OsmanThere is still no evidence-based guideline and consensus on the treatment Sydenham's Chorea (SC). The first-line medication preference of specialists depends on personal experience and is variable. In this study, we evaluate the treatment results of pediatric patients who were treated with valproic acid (VPA). The medical records of 17 patients diagnosed with SC were reviewed retrospectively. The mean time to clinical improvement was found as approximately 5 days, the mean duration of remission as 13.60 & PLUSMN; 3.94 weeks and the mean duration of medication use was found as 17.96 & PLUSMN; 3.81 weeks. No side effects were observed in any of the patients and relapse occurred in 2 patients. A positive correlation was found between the initial C-reactive protein (CRP) level and the duration of medication use. Until evidence-based guidelines are established, VPA can be used as an effective, safe, and inexpensive first-line treatment option, especially in pediatric patients.
